어린 알라스카 말라무트의 대퇴골에 발생한 골육종

지향,오상연,비둘,김현욱,최지혜,김대용,Jee, Hyang,Oh, Sang yeon,Pakhrn, Bidur,Kim, Hyun-wook,Choi, Ji-hye,Kim, Dae-yong 대한수의학회 2005 大韓獸醫學會誌 Vol.45 No.3

An 18-month-old male Alaskan malamute was euthanized due to slowly growing mass around the left femur after history of left posterior limb lameness. At necropsy, a firm confluent mass approximately 15cm in diameter was noted surrounding the femur and proximal portion of the tibia/ulna with traumatic ulceration of the overlying skin. On cross sections of the mass, many unencapsulated firm tan coalescing lobules were noted. The neoplasm consisted of closely packed spindle cells with homogenous eosinophilic material (osteoids) between the neoplastic cells. The pulmonary metastasis was confirmed. Based on the gross and histopathologic examinations, the case was diagnosed as juvenile osteosarcoma.

일반 고등학교 직업교육 위탁학생의 대인관계 상담과정에 대한 현상학적 접근

우지향(Jee Hyang Woo),김은영(Eun Young Kim) 학습자중심교과교육학회 2016 학습자중심교과교육연구 Vol.16 No.11

본 연구는 일반고등학교 직업교육 위탁학생을 대상으로 해결중심 상담을 진행하여 대인관계 문제 치유를 돕고, 학생들이 상담과정에서 경험한 것들의 의미와 가치를 질적 연구방법으로 탐색해 보고자 하였다. 직업교육 위탁학생이 상담과정에서 경험한 실체의 본질과 의미를 파악하기 위해 현상학적 연구방법을 적용하였다. 연구참여자는 서울소재 W고등학교 3학년에 재학 중인 직업교육 위탁학생 3명으로, 호소문제는 대인관계의 어려움이었고, 상담은 2015년 4월부터 6월까지 각각 6회기씩 진행하였다. 상담은 50분씩 진행하여 모두 녹음하였고, 비언어적 행동은 관찰일지에 기록하여 분석 자료로 활용하였다. 수집된 자료는 2015월 9월까지 Giorgi(1985)의 현상학적 분석방법과 절차에 따라 분석하였고, 11월까지 전문가 자문과 동료 및 연구참여자 검토를 거쳤다. 연구결과는 다음과 같다. 일반 고등학교 직업교육 위탁학생의 상담경험 분석을 통해 ‘관계회복의 의지와 실천’, ‘다양한 성공경험’, ‘중요한 타인들의 정서적 지지와 지원’, ‘긍정적인 자기상의 회복’이라는 4개의 범주를 도출하였다. 연구결과를 바탕으로 일반고등학교 직업교육 위탁학생의 심리·정서적, 교육적 지원에 대해 논의하였다. The aim of this research was to explore the meanings and values of clients counseling experiences during solution-focused counseling of high school students consigned to vocational education course. Participants for this study had interpersonal problems. Participants were 3 of adolescent clients(2 boys, 1 girls) who were having solution-focused counseling that 6 times at counseling office of school. For methodology, Giorgi’s descriptive phenomenological method was utilized. As a result of this study, it was identified that perceived counseling experience of adolescent clients are composed of 31 formulated meanings, 13 themes, and 4 categories. The results of the analysis revealed five categories of the essential themes of counseling experience : ‘willingness and practice of relationship recovery’, ‘success experience’, ‘emotional support of others’, ‘recovering of self-image’. Based on the results, the various supports of the consigned students in vocational education course were discussed and suggested.

학교상담자의 학교폭력 전담기구 업무와 다중관계 상담윤리 고찰

우지향(Jee-Hyang Woo) 숭실대학교 부부가족상담연구소 2021 가족과 상담 Vol.11 No.1

본 논문은 현행 학교폭력 전담기구 업무의 특성으로 인해 학교상담자가 윤리적 갈등상황에 부딪힐 수 있다는 문제의식에서 출발했다. 그동안 학교상담자의 학교폭력예방 관련 업무에 대해 상담윤리 측면에서 다룬 연구는 드물었다. 이에 법률에 규정된 학교폭력 전담기구의 업무와 학교상담자의 다중관계 윤리에 대해 살펴보았다. 학교폭력 전담기구 업무 수행 시 학교상담자가 부딪힐 수 있는 윤리적 쟁점은 학교폭력 관련 학교상담자 업무의 모호함으로 인한 역할혼선, 다중관계 측면에서 상담자 윤리갈등 촉발, 내담학생과의 상담관계 형성에 미치는 부정적 영향 등이다. 그 보완책으로 학교상담자의 윤리 민감성 제고와 실천 노력의 강조, 학교폭력 전담기구 업무를 상담윤리에 부합하도록 조정, 학교상담자 업무 세분화를 위한 인력재배치 및 확충, 국가 차원의 학교상담법 제정과 한국 실정에 적합한 학교상담자 윤리강령마련 등을 제안하였다. 학교상담 윤리강령에 대한 인식과 활용이 빈약한 현실에서 학교폭력 전담기구의 업무로 인한 다중관계 윤리 쟁점에 대해 살펴보고 보완책과 실태 파악을 위한 후속 연구를 제안했다는 점에 본 논문의 의의가 있다. This paper started from the consciousness of the problem that due to the characteristics of the work of the organization dedicated to school violence, the school counselors may encounter ethical conflict. Until now, there has been little research done on school counselors work related to school violence prevention in terms of counseling ethics. In this regard, the work of the organization dedicated to school violence as prescribed by the law and the counseling ethics of multiple relationships was examined. As a result, the following are the ethical issues that school counselors may encounter; confusion of roles due to unclear work of school counselors related to school violence, triggering counselor ethical conflicts in terms of multiple relationships, and negative effects on the formation of therapeutic relationships with clients. As a supplement to these issues, not only enhancing the ethical sensitivity of school counselors and emphasizing their efforts to practice them, but also adjusting the work of school counselors related to school violence to meet the counseling ethics, and rearranging and expanding manpower for subdividing the work of school counselors are suggested. Also, the enactment of the National School Counseling Act and the establishment of a code of ethics for school counselors suitable for the Korean situation are proposed. The significance of this review is that, in the reality that the recognition and use of the code of ethics for school counseling is poor, the issue of multi-relationship ethics arising from school violence-related work was examined, and supplementary measures and follow-up studies were proposed.

오골계와 백색산란계에서의 난소선암종

하정임,지향,임정묵,한재용,김대용,Ha, Jeong-Im,Jee, Hyang,Lim, Jung-Mook,Han, Jae-Yong,Kim, Dae-Yong 대한수의학회 2008 大韓獸醫學會誌 Vol.48 No.4

Necropsy was performed on a total of twenty three either white leghorn or ogol chickens which were more than 150 weeks of age. Among twenty three chickens examined, fifteen chickens were laying and the rest eight chickens were non-laying. On necropsy, neoplastic mass in the five chickens among non-laying chickens was found. These neoplastic masses were present mostly in the ovaries and one case in the liver and characterized by multifocal to coalescing 1 to 5 mm tan firm nodular formation. On histopathology, ovarian adenocarcinoma with widespread abdominal seeding and hepatic metastasis was diagnosed in the three chickens. Oviductal leiomyoma was also found in two chickens that had a focal well-demarcated nodules in the oviduct. Taken together, the number with ovarian adenocarcinoma among non-laying chickens over 150 week old was 37.5%. As most animal species do rarely develop ovarian tumors, the high rate of spontaneous ovarian adenocarcinoma in non-laying hen suggest that the hen is a proper model for human ovarian cancer study.

페렛에 발생한 소화기 림프종 1례

서경원,이종복,지향,이소라,권태억,김대용,윤화영,이창우,Seo, Kyoung-won,Lee, Jong-bok,Jee, Hyang,Lee, So-ra,Kwon, Tae-uk,Kim, Dae-yong,Youn, Hwa-young,Lee, Chang-woo 대한수의학회 2007 大韓獸醫學會誌 Vol.47 No.4

A 2-year-old spayed female ferret with the clinical signs of diarrhea and anorexia for about 8 days was presented to Hansung animal hospital. The diarrhea was black and paste form. Three palpable abdominal masses were detected in physical examination. By cytologic examination using fine need aspiration, the patient was tentatively diagnosed as lymphoma. Chemotherapy was started with prednisone, vincristine and cyclophosphamide. However, the client requested stopping the therapy at day 18 and the ferret was euthanized. Autopsy was performed and the masses were confirmed as lymphoma by histopathology. Microscopically, the mass consisted of unencapsulated and infiltrative neoplasm consisted of closely packed monomorphic round cells and also ininvasive lesions observed in duodenum. On the higher magnification, pleomorphic neoplastic cells with distinct cell border and abundant eosinophilic cytoplasm were observed. Finally, the ferret diagnosed as alimentary lymphoma.

개에서 국소형과 범발성형 조직구육종 2예

권효정,박미선,오상연,지향,조두연,김대용,Kwon, Hyo-Jung,Park, Mi-Sun,Oh, Sang-Yeon,Jee, Hyang,Cho, Doo-Youn,Kim, Dae-Yong 대한수의학회 2005 大韓獸醫學會誌 Vol.45 No.3

A male mixed breed dog with unknown age (case 1) and 5-year-old female golden retriever (case 2) were admitted to the Department of Veterinary Pathology at College of Veterinary Medicine, Seoul National University after sudden death. At necropsy, stifle region of case 1 was replaced by coalescing firm tan nodules approximately 1-3 cm in diameter. Neoplastic nodules were also presented in the lung. In case 2, the spleen was enlarged 3-5 times its normal size and numerous firm tan nodules were noted in the kidney, pericardium, diaphragm and lymph nodes. Histopathologically, the neoplastic masses of case 1 consisted of plump spindle cells having abundant cytoplasm and indistinct cell borders that formed interlacing bundle. In case 2, the masses were consisted of round to polygonal cells with abundant eosinophilic cytoplasm and eccentric nuclei. Numerous multinucleated giant cells containing nuclei of various sizes were noted. Immunohistochemically, neoplastic cells of all two cases stained intensely with vimentin and lysozyme. Based on the gross and light microscopic findings together with immunohistochemistry, both cases were diagnosed as localized histiocytic sarcoma with pulmonary metastasis and disseminated histiocytic sarcoma, respectively.

미나리 추출물의 기억력 손상 억제와 산화스트레스 억제 효과 및 Isorhamnetin 분석

원범영(Beom Young Won),신기영(Ki Young Shin),하현지(Hyun Jee Ha),위지향(Ji-Hyang Wee),윤여상(Yeo Sang Yun),김예리(Ye Ri Kim),박용진(Yong Jin Park),정경옥(Kyoung Ok Jung),성혜미(Hea Mi Sung),이형근(Hyung Gun Lee) 한국식품영양과학회 2016 한국식품영양과학회지 Vol.45 No.1

본 연구는 한국인이 일상생활에서 주로 상용하는 미나리에 대해 기억력 관련 효과와 항산화 효과, 미나리 추출물의 flavonoid 중 isorhamnetin을 분석하여 기능성식품 개발 및 이용에 기여하고자 실시하였다. Acetylcholinesterase의 활성 억제를 측정한 결과 화순미나리 추출물이 28.59%로 가장 높게 나타났으며, 나주미나리 추출물 25.11%와 유의적인 차이가 없었다. SH-SY5Y 세포사멸에 미치는 영향을 측정한 결과 DMSO와 비교하여 화순미나리 추출물 37.23%와 나주미나리 추출물 36.68%로 세포사멸이 유의적으로 감소하였다. 수동회피실험 결과 scopolamine 처리에 의해 기억력이 손상된 동물모델에서 미나리 추출물을 투여하였을 때 vehicle control보다 latency time이 높게 나타났다. DPPH 및 ABTS 라디칼 소거능 측정 결과 화순, 나주, 의령 미나리 추출물 모두 미나리 처리 그룹군 간에도 유의적 차이가 있었고(P<0.05), 화순미나리 추출물이 총 폴리페놀 함량 117 mg/g, 총 플라보노이드 함량 30 mg GAE/g으로 가장 높게 측정되었다. TBARS 측정 결과 미나리 추출물 440μg/mL의 농도에서 화순미나리 추출물이 50.7%의 억제력으로 가장 높았으며, 나주와 의령미나리 추출물보다 유의하게 높았다. 미나리 추출물의 플라보노이드 중 isorhamnetin을 분석한 결과 표준용액과 미나리 추출물의 머무름 시간이 14분대로 피크 유지시간이 일치하였으며, 동일한 spectrum을 나타내어 정확한 isorhamnetin의 분리를 확인하였다. 또한 LC/MS/MS를 통한 분석 결과 표준용액과 미나리 추출물에서 동일 시간대에 TIC를 확인하였고 precursor ion은 317 [M-H]+ m/z, product ion은 302 [M-H]+ m/z로 확인할 수 있었다. 이러한 연구 결과에 기초하여 미나리추출물은 천연 항산화제와 기억력 개선제로써의 활용 가치를 시사한다고 사료된다. 또한 건강기능성 소재로서 식품산업 분야의 이용률 향상에 도움이 될 것으로 판단된다. This study was conducted to investigate effect of the acetylcholinesterase inhibitor activity, the protective effect of the extract on SH-SY5Y cell death by H₂O₂, the memory improvement from scopolamine-induced rat. Moreover, the antioxidant activity of isorhamnetin from the dropwort (Oenanthe javanica) was investigated. Acetylcholinesterase inhibitor activity was highest (28.59%) in Hwasun O. javanica extract (H-OJE). H-OJE and Naju O. javanica extract (N-OJE) were not significantly different. SH-SY5Y cell death deceased to 37.23% and 36.68% for H-OJE and N-OJE, respectively, following treatment with the extracts. O. javanica extracts showed a protective effect against H₂O₂-induced neurotoxicity. Treatment with O. javanica extracts slightly improved scopolamine-induced (1 mg/kg, i.p.) memory impairment in rats. H-OJE contained the highest total phenolic and flavonoid contents of 117 mg/g and 30 mg gallic acid equivalents/g, respectively, and had a DPPH radical scavenging activity (SC50) of 113.8 μg/mL and ABTS radical scavenging activity of 48.2 μg/mL, which was higher than the other extracts. The thiobarbituric acid reactive substances value was highest (50.2%) in H-OJE. Antioxidant activity differed significantly among dropwort extracts. Isorhamnetin was known as one of the flavonoid and for having neuroprotective effect. So we analyzed acid-hydrolyzed O. javanica extract HPLC. The results were that peak at 14 min and spectrum of the extracts was consistent with standard solution. The results of LC/MS/MS analysis were that the extract and standard solution were confirmed total ion chromatogram at identical time, precursor ion was 317 [M-H]+ m/z, product ion was 302 [M-H]+ m/z. Overall, the results showed that the dropwort extract led to memory improvement and had antioxidant activity. Based on these finding, further research to investigate the production of ethanol extract of dropwort as a processed food is warranted.

만성신부전을 동반한 신장의 Oncocytomatosis 1예

이종욱,최현주,한진석,이정상,이창선,김연수,김성권,이서진,안규리,강지향,이공섭,홍종서,황보빈,김승협 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.6

Renal oncocytomas account for approximately 5% of renal parenchymal tumors. Usually it has unilateral solitary oncocytic nodule, but bilateral multifocal renal oncocytomasis is rare. The term renal oncocytoma should be used to characterize a well-differentiated renal epithelial tumor with eosinophilic granular cytoplasm that has benign behavior and favourable progress. Also, multiple oncocytoma distributed diffusely in both kidneys is termed renal oncocytomatosis. Because of the benign nature, multicentricity, possible bilaterality and absence of pathognomonic radiographic features, renal oncocytomas should be considered in differential diagnosis of solid masses, especially renal cell carcinoma. We report a patient with bilaleral multifocal renal oncocytomatosis, who had progressive renal failure. Renal oncocytomatosis was diagnosed pathologically after bilateral nephrectomy.