편마비 환자의 손 부종시 치료효과에 대한 연구

정복희,임호용,김제환,오명화 최신의학사 2003 最新醫學 Vol.46 No.9-10

제2형 당뇨병 환자에게 적용한 표준진료지침이 혈당, 당화혈색소, 당뇨지식 및 재원일수에 미치는 효과

김희승,윤건호,유양숙,오정아,송민선,신미옥,김경희,송복례 대한당뇨병학회 2002 임상당뇨병 Vol.3 No.1

연구배경 : 당뇨병 환자의 평균 재원기간을 단축시키고, 제한된 입원기간 내에서 질적인 면과 비용효과성을 고려한 총체적인 건강관리체계의 필요성이 요구됨으로써 생겨난 것이 당뇨병 표준진료지침(Critical Pathway: CP)이다. 현재 개발된 당뇨병 CP를 통한 진료가 환자의 당뇨병에 관한 지식을 개선시키고 이에 따라 장기적으로 당뇨병 환자의 혈당조절이 개선되었다는 과학적인 검증은 당뇨병 CP를 여러 병원에 정착시키기이전에 반드시 선행되어야 할 과제이다. 이에 본 연구는 2000년 3월부터 1년간 강남성모병원에 입원하는 당뇨병 환자를 대상으로 현재 개발된 1주일 CP를 적용한 실험군의 혈당, 당뇨병 관련 지식 및 재원일수가 대조군에 비하여 차이가 있는지를 조사하였다. 방법 : 1주일 CP를 적용한 실험군은 내과병동에 입원한 당뇨병 환자 89명이었고, 대조군은 기타병동에 입원한 당뇨병 환자 22명이었으며 CP를 적용하지 않았다. CP를 적용하기 전인 입원시에 실험군과 대조군의 공복혈당, 식후 2시간혈당, 당화혈색소 및 당뇨관련 지식을 측정하였고, 퇴원 시에 실험군과 대조군에게 공복혈당과 당뇨관련 지식을 재측정하고 재원일수를 파악하였다. 그리고 두 군에게 퇴원 3개월 후의 공복혈당, 식후 2시간 혈당 및 당화혈색소를 조사하였다. 결과 : 1) 실험군의 공복혈당은 입원 시 238.7: 1) 실험군의 공복혈당은 입원 시 238.7mg/dL에서 퇴원 시 139.4mg/dL로 감소하는 경향이었으나 퇴원 3개월 후에는 150.6mg/dL로 약간상승하는 경향을 보였다. 대조군은 입원 시 251.5mg/dL에서 퇴원 시 136.2mg/dL로 감소하는 경향이었으나, 퇴원 3개월 후에는 219.3mg/dL로 현저히 증가하는 경향이었다. 2) 실험군의 입원 시 식후 2시간 혈당은 312.5mg/dL에서 퇴원 3개월 후 248.5mg/dL로 감소하는 경향이었다. 대조군도 입원 시 식후 2시간 혈당이 300.1mg/dL에서 퇴원 3개월 후 262.5mg/dL로 감소하는 경향이었으나 실험군보다 감소의 폭이 적은 경향이었다. 3) 실험군과 대조군의 입원 시 당화혈색소는 각각 10.3%와 9.7%로 유의한 차이가 없었으나,퇴원 3개월 후 실험군은 7.5%로 대조군의 9.1% 보다 유의하게 감소하였다. 4) 실험군의 입원 시 당뇨지식 점수는 실험군이 12.1점 대조군은 12.0점으로 유의한 차이가 없었으나 퇴원 시는 실험군이 15.5점으로 대조군의 14.6점 보다 높은 경향이었다. 5) 재원일수는 실험군이 8.4일로 대조군의11.0일 보다 유의하게 적었다. 결론 : 따라서 당뇨병 환자를 위한 CP는 재원일수의 감소뿐만 아니라 환자의 자가관리에 대한 체계적인 교육과 개선의 기회를 가짐으로써 장기적인 혈당 조절의 향상을 도모할 수 있는 효과적인 방법이라고 생각한다. Background: The aim of this study was to examine the effects of the critical pathway for the admitted patients with type 2 dia betes me llitus on glycemic control, the knowledge on the disease, and the length of hospital stay. Methods: 89 diabetic in-patients were applied with the 1 week critical pathwa which was consisted of intensive education program for self-management of diabetes me llitus such as glucose monitoring, excercise prescription, diet control, self-a djustment of the drugs and so on. The results were compared with 22 diabetic inpatients who were treated with conventional way. We assessed the effects of critical pathway on the degree of glycemic control, the knowledge on the disease, and the length of hospital stay. Results: Although fasting and postprandial 2 hours blood g lucose levels did not showed sta tistically significantd ifference between critical pathway group and conventional group on discharge , HbA1c was significantly decreased in critical pathwa group compared with the conventional group (7.5±1.8% vs 9.1±2.6%) on 3 months after discharge . Knowledge on the disease tended to increase in critical pathway group compared with the conventional group on discharge. The Length of hospital stay was significantly decreased in critical pathway group compared with the conventional group (8.4±2.8day vs 11.0±3.9da ) Conclusion: These results showed that critical pathway for the patients with diabetes mellitus might be a usefulway for improving the long term glycemic control through motivation, enhancing the knowledge on the disase as well as reducing the length of hospital stay.

자기표현 훈련 프로그램의 개발과 효과성에 관한 연구

고희숙,오복희 원광대학교 2006 論文集 Vol.37 No.-

The purpose of this study was to verify the effects of the Assertiveness Training Program which was to improved the self-Assert of victim woman. This study method was conducted by "The pre and post tests, quasi-experimental group design", and "pre-post, improved scores of the measures of assertive test were done. Experimental subject was voluntary 4 woman which were advertised by K sexual violence counseling center. In case of experiment group, during the 7 weeks, a week, every two hours, total 14 hours, the program to Assert the self-Assert was performed. There was an evaluation in the program, program's frequency and used time, 7 sessions were a little longer, and a session, 2 hours were a little shorter. The results show that there was statistically significant improvement for the experimental group in all. In addition, the participants evaluations were generally positive about the program. Above all considering, there was an effectiveness to Assertiveness Training.

全羅南道 地域의 小兒와 개의 Campylobacter jejuni 保菌率

金臣武,吳賢淑,陳福熙 대한임상병리사협회 1984 임상병리사회지 Vol.16 No.1

중환자에서 동맥혈 가스분석 횟수와 그로인한 실혈량에 대한 연구

이석열,전철우,정영수,오희숙,마분란,이정미,정혜영,이만복,이길노 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Arterial blood gas analysis is the most comon exam in intensive care unit. In this study, the frequency of blood gas analysis and the amount of blood loss after Blood Gas Analysis in Intensive Care Unit were observed. Methods : From November 1999 to February 2000, 115 patients admitted to intensive care unit at Soonchunhyang university Kumi hospital were studied prospectively for the frequency of blood gas analysis and the amount of blood loss after blood gas analysis in Intensive Care Unit. Results : The mean value of frequency of blood gas analysis was 6.41±6.49 and the mean value of amount of blood loss after blood gas analysis was 0.78ml. This was lower than that of other foreign reports. The patients with ventilator therapy above 24 hours showed higher frequency of blood gas analysis than that of not applied ventilator patients. Pulse oxymetry was applied to all patients and the frequency of blood gas analysis was decreased due to the use of strict pulse oxymetry. Conclusion : Doctors and nurses in intensive care unit keep in mind that adequate blood sampling is needed for the decrease of blood loss. Education and protocol for the decrease of blood loss after arterial blood gas analysis may be necessary.

Neisseria gonorrhoeae 분리균의 항생제 내성 양상 분석

성원근,정경태,길준영,김석하,오희복 대한감염학회 2001 감염 Vol.33 No.5

Background : The aim of this study was to monitor trends in antimicrobial susceptibilities of Nesseria gonorrhoeae isolates, in particular, to examine the possibility of increasing prevalence of fluoroquinolone resistance in Korea and the relationship between patterns of mutations involving gyrA and parC genes and the ciprofloxacin resistance level. Methods : The antimicrobial susceptibilities of 489 gonoccocal isolates which were nationwide collected from patients visiting Health Centers were determined by NCCLS disk diffusion and agar plate dilution methods. PCR and direct DNA sequencing of the amplicons were performed to identify mutations within the quinolone resistance-determining regions of gyrA and parC genes. Results : The proportion of resistance to penicillin, tetracycline, or both remained as high as 94%. The isolates with ciprofloxacin resistance remarkably increased from 1% in 1999 to 5% in 2000 and also resistance to cefoxitine and ceftriaxone were shown to be increased. The strains resistant to spectinomycin was little reported. Four isolates with 16 ㎍/mL of MIC for ciprofloxacin all showed the same alternations of Ser-91 to Phe, Asp-95 to Gly in GyrA and Ser-87 to Arg in ParC, but ciprofloxacin-susceptible strains have little amino acid substitution. Conclusion : Considering the increasing prevalence of isolates with resistance to ciprofloxacin and ofloxacin, it is likely that the antibiotics such as spectinomycin, or ceftriaxone are recommended as the first-line treatment for gonoccocal infections in Korea. The results from this study suggest that mutation analysis for quinolone resistance-determining regions of gyrA and parC genes are important in epidemiological studies for the spread of ciprofloxacin resistant strains.(Korean J Infect Dis 33:338∼345, 2001)

Idetification of New serovar yeonchon and hongchon belonging to Leptospira interrogans Icterohaemorrhagiae Serogroup

Hee-Bok Oh(오희복),Woo-Hyun Chang(장우현),Min-Kee Cho(조민기),Won-Keun Seong(성원근),Kyung-Suk Park(박경석) 大韓微生物學會 1991 大韓微生物學會誌 Vol.26 No.3

HCV, Acute, LT : Epidemiologic Study for the Risk Factors of HCV Transmission

( Hee Bok Chae ),( Byung Seok Lee ),( An Na Kim ),( Tae Hee Lee ),( Soon Young Ko ),( Hong Soo Kim ),( Il Han Song ),( Jung Il Lee ),( Jeong Heo ),( Ki Tae Yoon ),( Oh Sang Kwon ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Background: In Korea, 1-2% of population is infected, and 15-20% of them have chronic liver diseases from HCV infection. On an annual basis, 3-4 million people are infected through blood transfusion, reckless drug abuse sexual contact, and exposure during childbirth. We want to know what risk factors contribute significantly to HCV infection in Korea. Methods: We surveyed 149 HCV-infected patients and 146 healthy controls (overall group) with a questionnaire to find out the risk factors related to HCV transmission. Results: The results were as follows. The statistically significant factors were ex-drinker, current smoking, history of acute hepatitis, having a HCV-positive family member, history of blood transfusion, acupuncture, moxa cautery, tatooing, sharing a razor, history of IV drug use, history of inhaled hallucinogen, more than one sexual partner, and history of venereal disease. We also performed a subgroup analysis according to their place of residence, inland group and coastal region group. The coastal region group was composed of 40 HCV-infected patients and 40 healthy controls. The statistically significant factors were ex-drinker, history of moxa cautery, tatooing, history of IV drug use, and history of inhaled hallucinogen. The inland group was composed of 106 HCV infected patients and 106 healthy controls. The statistically significant factors of inland group were similar to those of overall group. We found significant factors with multivariate analysis were revealed as follows, IV drug use (OR 14.73), history of acute hepatitis (OR 12.55), history of alcohol drinking (OR 7.46), tatooing (OR 3.64), moxa cautery (OR 3.64). Conclusions: The most important risk factor was IV drug use. The proportion of IV drug use patients in coastal region was two times as that of inland.(25% vs. 11.3%) Eighty seven percent of IV drug use patients experienced sharing of syringe with other people. Needle exchange program is recommended. Also, anti-HCV antibody test should be included in the test list of national health screening program, for people at age 40.

A New Peanut Variety “Daan” with High Yield and Disease Resistance

Suk-Bok Pae,Myung-Hee Lee,Sung-Up Kim,Chung-Dong Hwang,Ki-Won Oh,Chan-Sik Jung,Deuk-Young Song,In-Youl Baek,Young-Hee Lee 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Peanut is grown worldwide in the tropics and temperate zones primarily as an oilseed crop (38-54%) and protein source(25-30%). A new peanut variety “Daan”(Arachis hypogaea ssp. fastigiata L.) with the high yield potential was developed at the Department of Southern Area Crop Science, NICS, in Milyang in 2014. This was developed from the crossing line between cultivar “Sangpyeong” with short stem and high quality and “Dakwang” with large grain. “Daan” which is Shinpung plant type has 44cm of main stem length and 13 branch number per plant. Each pod has two grains with long ellipse shape of brown testa and yield components is composed of 34 mature pods of per plant, 127g of 100-seed weight, 75% of pod shelling ratio in the regional yield trials(RYT). Seed quality showed 47.8% of crude oil and 28.3% of protein content. This variety also showed more resistant to early leaf spot, late leaf spot, web blotch, stem rot and lodging compared with check variety “Daekwang”. In the regional yield trials “Daan” outyielded check variety by 16% with 5.00 MT/ha for kernel yield.

A New Dark Purple Peanut Variety “Heuksaeng”

Suk-Bok Pae,Chan-Sik Jung,Ki-Won Oh,Sung-Up Kim,Myung-Hee Lee,Chung-Dong Hwang,Deuk-Young Song,In-Youl Baek,Young-Hee Lee 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Anthocyanin has antioxidant and radical-scavenging effects which may protect cells from oxidative damage and reduce risk of cardiovascular diseases and cancer. A new peanut variety “Heuksaeng”(Arachis hypogaea ssp. hypogaea L.) with dark purple peanut skin was developed at the Department of Southern Area Crop Science, NICS, in Milyang in 2014. This variety was developed from the crossing line between cultivar “Iksan 31” with short stem and erect plant type and “Iksan35” with large grain and purple skin. “Heuksaeng” which is semi erect Virginia plant type has 32cm of main stem length and 25 branch number per plant. This also show more resistant to late leaf spot, web blotch and lodging, compared with check variety “Daekwang”. Each pod has two grains with ellipse shape of purple testa and its yield components is composed of 60 mature pods of per plant, 69g of 100-seed weight, 77% of pod shelling ratio in the regional yield trials(RYT). For 3 year regional yield trials the average kernel yield of “Heuksaeng” had 4.25 MT/ha similar to that of check variety. Its seed quality show 26.9% of crude protein and 46.0% of crude oil and 53.4% of oleate in fatty acid composition. Peanut skin of variety “Heuksang” consist of 2 kind of anthocyanin compounds such as 4.67mg/100g of delpinidine-3-glucoside (D3G) and 1.18mg/100g of cyanidine-3-glucoside(C3G). Peanut variety with high anthocyanin conent in skin will be useful to the recent preference of colorful food with healthful functional compounds.