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Krishnan, Hari B.,Kang, Beom Ryong,Hari Krishnan, Ammulu,Kim, Kil Yong,Kim, Young Cheol American Society for Microbiology 2007 Applied and environmental microbiology Vol.73 No.1
<B>ABSTRACT</B><P>Phenazine production was engineered in <I>Rhizobium etli</I> USDA9032 by the introduction of the <I>phz</I> locus of <I>Pseudomonas chlororaphis</I> O6. Phenazine-producing <I>R. etli</I> was able to inhibit the growth of <I>Botrytis cinerea</I> and <I>Fusarium oxysporum</I> in vitro. Black bean inoculated with phenazine-producing <I>R. etli</I> produced brownish Fix<SUP>−</SUP> nodules.</P>
Impact of Upper Limb Joint Fluid Variation on Inflammatory Diseases Diagnosis
Hari Krishnan G,Ananda Natarajan R,Anima Nanda 대한전기학회 2014 Journal of Electrical Engineering & Technology Vol.9 No.6
Joint pain is generally a common disorder not only for the old aged people but also for the immunocompromised patients. The present proposed study reveals the presence of inflammatory diseases in joint generally diagnosed by removing synovial fluid and changes in the volume and composition are examined for the presence of WBC and crystals. This study implement a non-invasive approach to identify the changes in joint fluid by measuring the changes in electrical property of the synovial tissue under the influence of electrical current signal with frequency range between 100 kHz to 300 kHz. The response of tissue for the current signal was measured in terms of potential drop across the tissue. The hardware system design consists of input and output sections. The input section which applies current signal to upper limb joint region is made of ICL8038 function generator IC with amplifier and voltage to current converter. The output section picks voltage variation using metal surface electrode, amplifier, ADC, PIC microcontroller and LCD interface. 100 patient inclusive of normal and disease affected patients where examined for upper limb synovial fluid variation and inflammatory diseases were identified.
Polarization Re-Configurable Antenna with Increase Gain for Small Satellites
Haris Mohammad,Khalil Ruhul Amin,Saeed Nasir 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.6
Future small satellites require the development of reconfi gurable antennas. Designing such antennas, especially single port patch antennas with circular polarization is a challenging task. Therefore, we propose both right-hand/left-hand circularly polarized (RHCP/LHCP) antenna which can reconfi gure. The proposed antenna follows patch topology with E-shape that is single-layer and single-feed with two RF switches. The switches can alter the polarization in real-time. We also show various properties of the proposed antenna, such as radiation pattern, impedance matching, axial ratio, and bandwidth through simulations and measurements. The proposed model shows excellent performance and agrees well with the measurements. The performance of the antenna shows an eff ective bandwidth of 2.45 GHz–2.82 GHz with a maximum gain of 9.88 dB at 2.55 GHz. The symmetry of the antenna radiation is preserved by switching between the LHCP and RHCP polarization modes.
Facile Synthesis of Pyranoxanthones, Dihydropyranoxanthones, and Their Analogues
Hari, Gala Sri,Lee, Yong-Rok Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.suppl8
This paper describes a concise and efficient synthetic route for the biologically interesting pyranoxanthones, dihydropyranoxanthones, and their derivatives. The key strategies involve pyranyl ring formation, methylation, catalytic hydrogenation, and catalytic dihydroxylation starting from 1,3-dihydroxyxanthen-9-one.
Hari P. Deka Boruah,Puneet S. Chauhan,Woo-Jong Yim(임우종),Gwang-Hyun Han(한광현),Tong-Min Sa(사동민) 한국토양비료학회 2010 한국토양비료학회지 Vol.43 No.1
무균 및 온실조건에서 indole-3-acetic acid (IAA)의 처리와 1-aminocyclopropane-1-carboxylate deaminase (ACCD) 및 IAA 활성을 갖는 Methylobacterium 균주 접종 시 토마토와 고추의 생장을 비교 평가하였다. 무균조건에서 1.0 ㎍ mL?¹의 IAA는 고추와 토마토의 뿌리생장을 촉진시키는데 비해 10.0 ㎍ mL?¹ 이상의 높은 농도에서는 뿌리생장이 억제되었다. 그러나 높은 ACCD 활성을 갖고, IAA 활성은 낮거나 가지고 있지 않은 Methylobacterium 균주들을 접종하였을 때에는 고추와 토마토 모두 IAA 처리구 보다 뿌리생장이 증진되는 것을 확인하였다. 마찬가지로 온실조건에서 Methylobacterium 균주들을 접종했을 때, 마디길이와 잎의 크기 그리고 단위 면적당 잎의 무게(SLW)에서 유의성 있는 증진효과를 보였다. 전반적인 식물 생장에서 저농도의 IAA 처리 효과는 Methylobacterium의 효과와 비슷한 경향을 나타냈다. 유묘의 지상부 길이는 ACCD 활성과 IAA 생산능을 갖는 Methylobacterium 균주 처리구에서 유의성 있는 증가를 확인할 수 있었으며, 전체 건물중 또한 Methylobacterium 처리 시 유의성 있는 증진 효과를 확인 할 수 있었다. 하지만 고농도의 IAA는 고추와 토마토의 생물량을 억제시켰다. 이러한 결과는 접종 균주의 IAA와 ACCD가 고추와 토마토 유묘의 생장 증진에 영향을 끼친다는 것을 증명한다. A comparative study was performed in gnotobiotic and greenhouse conditions to evaluate the effect of exogenous application of indole-3-acetic acid (IAA) and inoculation of Methylobacterium spp. possessing 1-aminocyclopropane-1-carboxylate deaminase (ACCD) and IAA activity on red pepper and tomato seedling growth and development. Application of 1.0 ㎍ mL?¹ IAA positively influenced root growth while high concentrations (>10.0 ㎍ mL?¹) suppressed root growth of red pepper and tomato under gnotobiotic condition. On the other hand, inoculation of Methylobacterium strains with ACCD activity and IAA or without IAA enhanced root growth in both plants. Similarly, under greenhouse condition the inoculation of Methylobacterium sp. with ACCD activity and IAA enhanced plant fitness recorded as average nodal length and specific leaf weight (SLW) but the effect is comparable with the application of low concentrations of IAA. Seedling length was significantly increased by Methylobacterium strains while total biomass was enhanced by Methylobacterium spp. and exogenous applications of < 10.0 ㎍ mL?¹ IAA. High concentrations of IAA retard biomass accumulation in red pepper and tomato. These results confirm that bacterial strains with plant growth promoting characters such as IAA and ACCD have characteristic effects on different aspects of growth of red pepper and tomato seedlings which is comparable or better than exogenous applications of synthetic IAA.
Expression Profile of Genes Modulated by Aloe emodin in Human U87 Glioblastoma Cells
Haris, Khalilah,Ismail, Samhani,Idris, Zamzuri,Abdullah, Jafri Malin,Yusoff, Abdul Aziz Mohamed Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11
Glioblastoma, the most aggressive and malignant form of glioma, appears to be resistant to various chemotherapeutic agents. Hence, approaches have been intensively investigated to targeti specific molecular pathways involved in glioblastoma development and progression. Aloe emodin is believed to modulate the expression of several genes in cancer cells. We aimed to understand the molecular mechanisms underlying the therapeutic effect of Aloe emodin on gene expression profiles in the human U87 glioblastoma cell line utilizing microarray technology. The gene expression analysis revealed that a total of 8,226 gene alterations out of 28,869 genes were detected after treatment with $58.6{\mu}g/ml$ for 24 hours. Out of this total, 34 genes demonstrated statistically significant change (p<0.05) ranging from 1.07 to 1.87 fold. The results revealed that 22 genes were up-regulated and 12 genes were down-regulated in response to Aloe emodin treatment. These genes were then grouped into several clusters based on their biological functions, revealing induction of expression of genes involved in apoptosis (programmed cell death) and tissue remodelling in U87 cells (p<0.01). Several genes with significant changes of the expression level e.g. SHARPIN, BCAP31, FIS1, RAC1 and TGM2 from the apoptotic cluster were confirmed by quantitative real-time PCR (qRT-PCR). These results could serve as guidance for further studies in order to discover molecular targets for the cancer therapy based on Aloe emodin treatment.