http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Characterization of Spermatogonial Stem Cells and Testicular Cells in Chicken
Bo Ram Lee,Young Mok Lee,Tae Sub Park,Jin Geyoung Jung,Yeong Ho Hong,Jeong Mook Lim,Jae Yong Han 한국가금학회 2003 한국가금학회 정기총회 및 학술발표회 Vol.20 No.-
정원세포는 수컷의 정소에 존재하며, 감수분열을 통하여 정자를 형성하고 지속적으로 자신의 복제가 가능한 세포이다. 이러한 정원세포는 마우스를 중심으로 현재 수컷불임 치료의 연구, 멸종위기 종의 보존을 위한 연구 그리고 형질전환 동물 생산 등 다양한 분야에 응용되고 있다. 그러나 조류에서는 정원세포 연구에 있어서 그 세포의 형태적ㆍ면역학적 특성이 아직 구명되지 못하여 연구진행에 어려움이 많다. 따라서 본 연구에서는 전자주사현미경을 이용하여 세포내 구조와 형태의 분석을 진행하였고, 조직염색법을 통하여 특이적 마커를 분석하였다. 이후 본 연구결과를 토대로, 포유류에서 이루어진 정원세포 이식기술의 개발 및 새로운 형질전환 기술의 개발을 조류응용이 가능할 것이다. According to topographical methods, the chicken spermatogonia was located in basal membrane of seminiferous tubules. It has large nuclei and mitochondria and proliferated with cellular bridges. Immunohistochemistry data showed that anti-SSEA-1 antibody specifically reacted with Apr and Aal type spermatogonia. Lectin, STA and integrin-6, -1 were also specific to As type spermatogonia.
Lee, Bo Ram,Lee, Wonho,Nguyen, Thanh Luan,Park, Ji Sun,Kim, Ji-Seon,Kim, Jin Young,Woo, Han Young,Song, Myoung Hoon American Chemical Society 2013 ACS APPLIED MATERIALS & INTERFACES Vol.5 No.12
<P>Highly efficient inverted-type red-emitting hybrid polymeric light-emitting diodes (HyPLEDs) were successfully demonstrated via Förster resonance energy transfer (FRET) and interfacial engineering of metal oxide with a cationic conjugated polyelectrolyte (CPE). Similarly structured green- and red-emissive polyfluorene copolymers, F8BT and F8TBT, were homogeneously blended as a FRET donor (host) and acceptor (dopant). A cationic polyfluorene-based CPE was also used as an interfacial layer for optimizing the charge injection/transport and improving the contact problem between the hydrophilic ZnO and hydrophobic polymer layer. A long Förster radius (<I>R</I><SUB>0</SUB> = 5.32 nm) and high FRET efficiency (∼80%) was calculated due to the almost-perfect spectral overlap between the emission of F8BT and the absorption of F8TBT. A HyPLED containing 2 wt % F8TBT showed a pure red emission (λ<SUB>max</SUB> = 640 nm) with a CIE coordinate of (0.62, 0.38), a maximum luminance of 26 400 cd/m<SUP>2</SUP> (at 12.8 V), a luminous efficiency of 7.14 cd/A (at 12.8 V), and a power efficiency of 1.75 lm/W (at 12.8 V). Our FRET-based HyPLED realized the one of the highest luminous efficiency values for pure red-emitting fluorescent polymeric light-emitting diodes reported so far.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2013/aamick.2013.5.issue-12/am401090m/production/images/medium/am-2013-01090m_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am401090m'>ACS Electronic Supporting Info</A></P>
( Bo Ram Lee ),( Yu Il Kim ),( Chul Min Ahn ),( Ji Ye Jung ),( Ju Ock Kim ),( Jin Young An ),( Hyoung Kyu Yoon ),( Sang Haak Lee ),( Yeong Hun Choe ),( Chang Hoon Han ),( Joo Hun Park ),( Jae Yeol Kim 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: A simple chest x-ray (CXR) is commonly used to examine the chest and lung disease. There are few reports on the prevalence of CXR abnormalities in the general population. We aimed to investigate the prevalence of abnormalities seen on CXR in the general population and risk factors including smoking associated with these abnormalities. Methods: We analyzed the data of the 4th and 5th Korea National Health and Nutrition Examination Survey; a cross-sectional survey in the general population of Korea. A total of 27,936 subjects aged 19 years or more were enrolled in this study. CXR fi ndings were categorized into 5 groups; normal, tuberculosis (active or inactive), lung nodule or cancer or mediastinal disease, active other lung diseases, inactive other lung diseases. The amount of smoking was classifi ed as never, =15 pack-years, and >15 pack-years. Results: The prevalence of CXR abnormalities was 12.8 % (n=3180); 9.5% in never- smokers, 9.9% in smokers who had smoked =15 pack-years, 19.1% in smokers who had smoked >15 pack-years. The most common abnormal fi nding was pulmonary tuberculosis. Signifi cant independent risk factors for CXR abnormalities by multivariate analysis were age (40-59 years: odds ratio [OR], 3.40; 95% confi dence interval [CI], 2.93 - 3.93; = 60 years: OR, 9.81; 95% CI, 8.52 - 11.29), sex (male) (OR, 1.68; 95% CI, 1.50 - 1.88) and smoking amount (>15 pack-years) (OR, 1.19; 95% CI, 1.05 - 1.35). Conclusions: Abnormalities on CXR were more prevalent in moderate to heavy smokers, older subjects and men in the general population. The prevalence increased with increased amount of smoking. Since cigarette smoking is a preventable risk factor for lung disease, efforts are needed for smoking cessation in the community.
( Bo Ram Lee ),( Yu Il Kim ),( Chul Min Ahn ),( Ji Ye Jung ),( Ju Ock Kim ),( Jin Young An ),( Hyoung Kyu Yoon ),( Sang Haak Lee ),( Yeong Hun Choe ),( Chang Hoon Han ),( Joo Hun Park ),( Jae Yeol Kim 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Background: A simple chest x-ray (CXR) is commonly used to examine the chest and lung disease. There are few reports on the prevalence of CXR abnormalities in the general population. We aimed to investigate the prevalence of abnormalities seen on CXR in the general population and risk factors including smoking associated with these abnormalities. Methods: We analyzed the data of the 4th and 5th Korea National Health and Nutrition Examination Survey; a cross-sectional survey in the general population of Korea. A total of 27,936 subjects aged 19 years or more were enrolled in this study. CXR findings were categorized into 5 groups; normal, tuberculosis (active or inactive), lung nodule or cancer or mediastinal disease, active other lung diseases, inactive other lung diseases. The amount of smoking was classified as never, =15 pack-years, and >15 pack-years. Results: The prevalence of CXR abnormalities was 12.8 % (n=3180); 9.5% in never-smokers, 9.9% in smokers who had smoked =15 pack-years, 19.1% in smokers who had smoked >15 pack-years. The most common abnormal finding was pulmonary tuberculosis. Significant independent risk factors for CXR abnormalities by multivariate analysis were age (40-59 years: odds ratio [OR], 3.40; 95% confidence interval [CI], 2.93 - 3.93; = 60 years: OR, 9.81; 95% CI, 8.52 - 11.29), sex (male) (OR, 1.68; 95% CI, 1.50 - 1.88) and smoking amount (>15 pack-years) (OR, 1.19; 95% CI, 1.05 - 1.35). Conclusions: Abnormalities on CXR were more prevalent in moderate to heavy smokers, older subjects and men in the general population. The prevalence increased with increased amount of smoking. Since cigarette smoking is a preventable risk factor for lung disease, efforts are needed for smoking cessation in the community.
Real-time detection of chlorine gas using Ni/Si shell/core nanowires
Lee, Dong-Jin,Heo, Kwang,Lee, Hyungwoo,Jin, Joon-Hyung,Chang, Hochan,Park, Minjun,Lee, Han-Bo-Ram,Kim, Hyungjun,Lee, Byung Yang Springer US 2015 NANOSCALE RESEARCH LETTERS Vol.10 No.1
<P>We demonstrate the selective adsorption of Ni/Si shell/core nanowires (Ni-Si NWs) with a Ni outer shell and a Si inner core on molecularly patterned substrates and their application to sensors for the detection of chlorine gas, a toxic halogen gas. The molecularly patterned substrates consisted of polar SiO<SUB>2</SUB> regions and nonpolar regions of self-assembled monolayers of octadecyltrichlorosilane (OTS). The NWs showed selective adsorption on the polar SiO<SUB>2</SUB> regions, avoiding assembly on the nonpolar OTS regions. Utilizing these assembled Ni-Si NWs, we demonstrate a sensor for the detection of chlorine gas. The utilization of Ni-Si NWs resulted in a much larger sensor response of approximately 23% to 5 ppm of chlorine gas compared to bare Ni NWs, due to the increased surface-to-volume ratio of the Ni-Si shell/core structure. We expect that our sensor will be utilized in the future for the real-time detection of halogen gases including chlorine with high sensitivity and fast response.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1186/s11671-015-0729-2) contains supplementary material, which is available to authorized users.</P>
Lee, Han-Bo-Ram,Gu, Gil Ho,Son, Jong Yeog,Park, Chan Gyung,Kim, Hyungjun WILEY-VCH Verlag 2008 Small Vol.4 No.12
<P>A novel fabrication method of Co and Ni metal nanorods (NRs) without catalyst or template, based on the spontaneous formation of NRs during plasma-enhanced atomic layer deposition (PE-ALD) is developed. Pure Co and Ni NRs 9–10 nm in diameter are synthesized on SiO<SUB>2</SUB> and Si substrates by using metal–organic precursors and an NH<SUB>3</SUB> plasma mixed with a suitable amount of SiH<SUB>4</SUB> as a reactant. The lengths of the NRs are controlled on the nanometer scale by changing the number of PE-ALD growth cycles. Superconducting quantum interference device magnetometer measurements confirm the magnetic anisotropy of Co NRs caused by shape anisotropy.</P> <B>Graphic Abstract</B> <P>Nanorods grow up: Co and Ni nanorods (NRs) are fabricated without catalyst or template by the spontaneous formation of NRs during plasma-enhanced atomic layer deposition (PE-ALD; see picture). Pure metal NRs 9–10 nm in diameter are synthesized on SiO<SUB>2</SUB> and Si substrates by using metal–organic precursors and an NH<SUB>3</SUB> plasma mixed with SiH<SUB>4</SUB> as reactant. <img src='wiley_img/16136810-2008-4-12-SMLL200801074-content.gif' alt='wiley_img/16136810-2008-4-12-SMLL200801074-content'> </P>