Selection of Fruit Quality Assessment Factors for Peach Genus

Haiying Zhang,Younian Wang 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

Zhang Haiying,Kim Hyeok,Park Bong Woo,Noh Minyoung,Kim Yeomyeong,Park Jeongeun,Park Jae-Hyun,Kim Jin-Ju,Sim Woo-Sup,Ban Kiwon,Park Hun-Jun,Kwon Young-Guen 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Ischemia–reperfusion (I/R) injury accelerates the cardiomyocytes (CMs) death by oxidative stress, and thereby deteriorates cardiac function. There has been a paradigm shift in the therapeutic perspective more towards the prevention or amelioration of damage caused by reperfusion. Cardiac microvascular endothelial cells (CMECs) are more vulnerable to reperfusion injury and play the crucial roles more than CMs in the pathological process of early I/R injury. In this study, we investigate that CU06-1004, as a vascular leakage blocker, can improve cardiac function by inhibiting CMEC’s hyperpermeability and subsequently reducing the neutrophil’s plugging and infiltration in infarcted hearts. CU06-1004 was delivered intravenously 5 min before reperfusion and the rats were randomly divided into three groups: (1) vehicle, (2) low-CU06-1004 (1 mg/kg, twice at 24 h intervals), and (3) high-CU06-1004 (5 mg/kg, once before reperfusion). CU06-1004 treatment reduced necrotic size and cardiac edema by enhancing vascular integrity, as demonstrated by the presence of intact junction proteins on CMECs and surrounding pericytes in early I/R injury. It also decreased the expression of vascular cell adhesion molecule 1 (VCAM-1) on CMECs, resulting in reduced infiltration of neutrophils and macrophages. Echocardiography showed that the CU06-1004 treatment significantly improved cardiac function compared with the vehicle group. Interestingly, single high-dose treatment with CU06-1004 provided a greater functional improvement than repetitive low-dose treatment until 8 weeks post I/R. These findings demonstrate that CU06-1004 enhances vascular integrity and improves cardiac function by preventing lethal myocardial I/R injury. It can provide a promising therapeutic option, as potential adjunctive therapy to current reperfusion strategies.

Progressive Collapse Behavior of Large-span Truss String Structures Subjected to Cable Failure

Haiying Zhang,JinYu Lu,Xiaolong Wu,Na Li 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.4

Cables play an important role in truss string structures, and their sudden failure can lead to massive damage and even collapse of the structures. This paper studies the dynamic response of a 72 m span truss string structure, the progressive collapse numerical simulation of the structure is carried out under different load conditions, the displacement and force responses of the structure after cable failure are investigated, the dynamic amplification factor is calculated, and the collapse mechanism is revealed. The effect of individual factor changes on the structural response is analyzed and compared. Results showed that after cable failure, the stress state of the upper truss changed from an arch to a simply supported beam, when reaching collapse load, the structure collapsed within 5s instead of reaching new equilibrium positions. Moreover, the structure with stiffer elastic support exhibited higher resistance to collapse. The critical member of the truss, which first buckled under compression, shifted from the mid-span to the lower chord at the end, leading to rapid structural collapse. Increasing the cable's cross-sectional area can hardly reduce the structure's dynamic response. However, when the instantaneous failure time of the cable exceeded 0.1s, a significant alleviation of the structure's dynamic response was observed.

Comparison on Postharvest Physiological Changes between Mid-Season and Late-Season Maturing Peaches

Haiying Zhang,Tao Han 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

[특집: 동아시아 상인 열전-상인(商人)의 창을 통해 역사를 보다-] : 14∼18세기 중국-조선의 민간무역과 상인(商人)

장해영 ( Haiying Zhang ) 고려대학교 민족문화연구원 2015 民族文化硏究 Vol.69 No.-

明淸時期 중국과 조선의 무역은 朝貢貿易, 使臣貿易, 官의 “和買”貿易 등 官 주도의 다양한 형태의 무역이 있었지만, 民間貿易은 정부정책 등의 요소로 인해 늘 일종의 제한된, 심지어 금지된 형태에 처해 있었다. 명초 동남연해의 海禁 정책으로 인해 조선과의 무역 역시 정부의 엄격한 관리 하에 있었던 것이다. 그렇지만 바로 이 시기에도 다수의 민간 상인들은 최대한 정부 정책을 이용해 허가를 받아 중국과 조선을 왕래하며 여러 가지 형태로 상업 활동을 펼치고 있었다. 또한 일부 상인들은 밀무역의 형식을 통해서 불법적인 무역을 진행하기도 했다. 본고는 明淸 시대를 중심으로 중국-조선 간 民間貿易의 발전 양상과 민간무역에서의 두 나라 商人들의 역할과 運命의 推移를 살펴보았다. 이 부분에 대한 기존 학계의 연구 성과가 매우 적기 때문에, 본 연구는 동북아시아 지역 경제와 관련된 역사를 인식하는 데 적지 않은 의의가 있을 것이다. The bilateral trade between China and Korea was led by the states of the two countries in the period of the 14th - 18th centuries. The trade consisted of two parts: the state-run trade, or official trade, which included the tribute trade, envoy trade, government purchase and sales, etc., and private trade, or non-official trade, was run by common merchants. Subjected to the government policies and other factors, private trade was restricted usually and even forbidden sometimes. In particular, the Korean trade was under the strict control of the Chinese government, partly because of the Chinese maritime prohibition police against the Japanese pirates which was rampant in the period. Even so, however, many private merchants, using the room to the extent permitted by the state policies, plied between China and Korea and carried out their commercial activities of various types. Some of them were even engaged in smuggling and other illegal trade. This private trade was important in the East Asian international trade. It in particular played a significant role in the Sino-Korean trade, which strengthened economic links between the two countries. Through combing out and analyzing historical materials from different sources, this article will focus on the practical performance in the Sino-Korean private trade in this period and the fates of these merchants who were working in this trade. Since few works have been done in this subject in previous scholarship, this study will be important to our understanding of the history of economic relations in East Asia.

Dynamics and Optimized Torque Distribution Based Force/position Hybrid Control of a 4-DOF Redundantly Actuated Parallel Robot with Two Point-contact onstraints

Haiying Wen,Ming Cong,Guifei Wang,Wenlong Qin,Weiliang Xu,Zhisheng Zhang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.5

A 4-DOF redundantly actuated parallel robot (RAPR) for jaw movement achieved by adding two pointcontactconstraints (higher-kinematic-pairs, HKPs) is presented. The inverse dynamics and driving force optimizationmodel based on pseudo-inverse method are established. In order to overcome the disequilibrium of drivingforces of the redundant chains caused by inclusion of point-contact constraints, an optimized torque distributionbased force/position hybrid control (OTDFP control) method for trajectory tracking is proposed for this RAPR. Experiments are carried out to evaluate the OTDFP control. Comparison with the conventional position control isperformed, showing that the OTDFP control can reduce torque fluctuation and tracking errors of the RAPR. Thechewing experiment of silicone shows the RAPR is not only able to track mandibular movement, but also able toemulate chewing force and temporomandibular joint (TMJ) force under the OTDFP control.

Effect of divalent manganese (Mn 2+ ) concentration on the growth and nitrate nitrogen content of lettuce during aeroponic intercropping with cherry radish

Lei Zhang,Linlin Wang,Faqinwei Li,Fei Xiao,Haiye Yu 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.2

Artemisia princeps (Ganghwa wormwood) is a medicinal plant that produces two major fl avonoids, eupatilin and jaceosidin, which are used in the treatment of gastritis and peptic ulcers. A. princeps is primarily fi eld cultivated, which has some drawbacks, including only one cultivation period per year and variations in fl avonoid production due to environmental changes. The objective of this study was to analyze the eff ects of seasonal light variation and artifi cial light treatments on the growth and fl avonoid production of A. princeps grown in greenhouses for year-round production. The plants were cultivated and harvested nine times in one year under natural seasonal light conditions in greenhouses. During the winter growth period (when natural light is substantially lower), four artifi cial light treatments were applied during two cultivation periods, from September 2016 to January 2017: supplemental light, night interruption, low light, and low light with night interruption. The plants grown under the natural light condition in greenhouses were used as a control. After harvest, the growth of the plants was measured, and the contents of eupatilin and jaceosidin were determined. The plants had the highest biomass when the accumulated radiation and duration were highest. The growth and fl avonoid production were signifi cantly associated with accumulated radiation and light duration. The supplemental light and night interruption treatments resulted in signifi cantly higher biomass and fl avonoid production, with the night interruption treatment requiring less energy input than the supplemental light treatment. Therefore, for consistent biomass and fl avonoid production of A. princeps , a night interruption treatment is suggested in greenhouse cultivation during low irradiation and short days (less than 13 h).

Association of the KAP 8.1 Gene Polymorphisms with Fibre Traits in Inner Mongolian Cashmere Goats

Liu, Haiying,Yue, Chun-Wang,Zhang, Wei,Zhu, Xiaoping,Yang, Guiqin,Jia, Zhihai Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.10

The objective of this study was to investigate polymorphisms of keratin-associated protein 8.1 (KAP8.1) gene and its effect on fibre traits of Chinese Inner Mongolian Cashmere goats. The fibre traits data investigated were cashmere fibre diameter, combed cashmere weight, cashmere fibre length and guard hair length. Five hundred and forty animals were used to detect polymorphisms in the complete coding sequence of the hircine KAP8.1 gene by means of PCR-SSCP. The results identified six genotypes, AA, BB, CC, AB, AC and BC, coded for by three different alleles A, B and C. Two SNPs in the coding region were confirmed by sequencing, which were T113G and G116C respectively. The relationships between the genotypes and cashmere fibre diameter, combed cashmere weight, cashmere fibre length and guard hair length were analyzed. There were significant differences between the associations of the different genotypes with cashmere weight (p<0.01), cashmere length (p<0.05) and hair length (p<0.01). Cashmere fibre diameter was the only trait that was not associated with the genotypes. The animals of genotype AB and BB had the higher cashmere weight compared with the genotype AA. By further analysis, it appeared that the KAP8.1 genotype effects on fibre traits may be due to a mutation at the 113 locus. These results suggested that polymorphisms in the hircine KAP8.1 gene might be a potential molecular marker for cashmere weight in Cashmere goats.

Homing and Restorative Effects of Bone Marrow-Derived Mesenchymal Stem Cells on Cisplatin Injured Ovaries in Rats

Liu, Jiabin,Zhang, Haiying,Zhang, Yun,Li, Nan,Wen, Yuku,Cao, Fanglei,Ai, Hao,Xue, Xiaoou Korean Society for Molecular and Cellular Biology 2014 Molecules and cells Vol.37 No.12

Premature ovarian failure (POF) is a long-term adverse effect of chemotherapy treatment. However, current available treatment regimens are not optimal. Emerging evidence suggests that bone marrow-derived mesenchymal stem cells (BMSCs) could restore the structure and function of injured tissues, but the homing and restorative effects of BMSCs on chemotherapy injured ovaries are still not clear. In this study, we found that granulosa cell (GC) apoptosis induced by cisplatin was reduced when BMSCs were migrated to granulosa cells (GCs) in vitro. Chemotherapy-induced POF was induced by intraperitoneal injection of cisplatin in rats. BMSCs labeled with enhanced green fluorescent protein (EGFP) were injected into the rats via the tail vein to investigate the homing and distribution of BMSCs in vivo. The number of BMSCs in the ovarian hilum and medulla was greater than in the cortex, but no BMSCs were found in the follicles and corpus lutea. In addition, the BMSCs treatment group's antral follicle count and estradiol levels increased after 30 days, compared with the POF group. Hence, our study demonstrates that intravenously delivered BMSCs can home to the ovaries, and restore its structure and function in POF model rats.

Homing and Restorative Effects of Bone Marrow-Derived Mesenchymal Stem Cells on Cisplatin Injured Ovaries in Rats

Jiabin Liu,Haiying Zhang,Yun Zhang,Nan Li,Yuku Wen,Fanglei Cao,Hao Ai,Xiaoou Xue 한국분자세포생물학회 2014 Molecules and cells Vol.37 No.12

Premature ovarian failure (POF) is a long-term adverse effect of chemotherapy treatment. However, current available treatment regimens are not optimal. Emerging evidence suggests that bone marrow-derived mesenchymal stem cells (BMSCs) could restore the structure and function of injured tissues, but the homing and restorative effects of BMSCs on chemotherapy injured ovaries are still not clear. In this study, we found that granulosa cell (GC) apoptosis induced by cisplatin was reduced when BMSCs were migrated to granulosa cells (GCs) in vitro. Chemo-therapy-induced POF was induced by intraperitoneal injection of cisplatin in rats. BMSCs labeled with enhanced green fluorescent protein (EGFP) were injected into the rats via the tail vein to investigate the homing and distribution of BMSCs in vivo. The number of BMSCs in the ovarian hilum and medulla was greater than in the cortex, but no BMSCs were found in the follicles and corpus lutea. In addition, the BMSCs treatment group’s antral follicle count and estradiol levels increased after 30 days, compared with the POF group. Hence, our study demonstrates that intravenously delivered BMSCs can home to the ovaries, and restore its structure and function in POF model rats.