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RISS 인기검색어
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- 저자 : Hairong Li (검색결과 6 건)
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Fan Yang,Hairong Xiong,Li Duan,Qian Li,Xin Li,Yongqin Zhou 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4
Purpose MicroRNAs (miRNAs) are a group of small non-coding RNAs involved in different cancers, including lung cancer. Here, we aim to investigate the expression profiles of circulating miRNAs and their roles contributed to the progress of lung cancer. Materials and Methods The levels of circulating miRNA in lung cancer patients were investigated by miRNAs assay. Then we predicted the target genes of aberrantly expressing miRNAs by searching genetic databases. Based on the A549 cells transfected with miR-1246 mimics or miR-1246 inhibitor, we further measured the roles of miR-1246 involving in the epithelial-mesenchymal transition (EMT), migration and invasion capacities of lung cancer cells in vitro. Finally, we detected the effects of miR-1246 on glycogen synthase kinase-3β (GSK-3β)/β-catenin pathway by immunofluorescence and Western blot, respectively. Results We identified that 14 miRNAs were aberrantly expressed in the serum of lung cancer patients. Among them, miR-1246 was the most up-regulated. The cell assays indicated that miR-1246 significantly increased the migration and invasion capabilities of A549 lung cancer cells. Meanwhile, immunofluorescence analysis revealed that miR-1246 promoted EMT process of A549 cells accompanying with decreasing E-cadherin expression, while increasing vimentin and transforming growth factor β expression. Furthermore, an online tool predicated that miR-1246 might bind to 3'-untranslated region of GSK-3β, which was confirmed by overexpression and knockdown of miR-1246 assays. Conclusion Taken together, the study illustrates that miR-1246 regulates Wnt/β-catenin pathway through targeting GSK-3β/β-catenin, which partly contributing to tumor metastasis. MiR- 1246 may play an essential role in the diagnosis and therapeutic of lung cancer.
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Study on Half-Bridge Voltage Balancing Circuit with Two Driving Methods
Zhang Xianjin,Zhu Hairong,Wu Di,Li Rui 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.3
A voltage balancing circuit not only can split a two-wire dc grid into a three-wire dc grid, but also can balance the voltages of series capacitors or battery packs. A half-bridge voltage balancing circuit is a simpler topology and is widely introduced. But it has not been deeply analysed. Thus, in this paper the balancing circuit with the complementary driving method is studied in detail, fi rstly. Secondly, for avoiding the reactive current occurred in the complementary driving method, the unipolar current driving method is also proposed. Finally, the prototype is implemented in the lab, and the simulation and experimental results verify the analyses.
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Yao Lu,Zhe Li,Gebremariam Hailu,Derong Xu,Hairong Wu,Wanli Kang 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.72 No.-
The existing downhole oil–water separation (DOWS) technology has disadvantages in terms ofseparation efficiency, cost, complexity, etc. The novelfiltration separation technology using metalmeshes has been investigated and it displays the potential to increase DOWS efficiency. In current study, asuper-hydrophobic copper mesh was fabricated by a simple dip-coating method and then characterized. Focusing on the application in DOWS technology, the separation of the mesh materials in the liftingprocess of produced liquid from the wellbore was simulated and investigated by a designed indoor devicefor thefirst time. The results show that the highly hydrophobic copper mesh with water contact angle of153 can be obtained by oxidizing 40 min, followed by immersing in a 50 g L 1 stearic acid solution for25 min. The mesh can keep super-hydrophobicity and high separation stability after treatment at 100 Cor in the pH range of 5–7, while the separation efficiency is susceptible to the oil viscosity and the claycontents of the producedfluids. The super-hydrophobic copper mesh can be a promising candidate forDOWS in moderate condition. The inherent separation mechanism was further discussed by the variationof wettability and surface structure in microscopic scale.
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Current progress on gold recovery from refractory ore and waste electrical and electronic equipment
Ji Xuran,Shen Zhijie,Xu Wenping,Yao Shimiao,Zhang Hairong,Xiong Lian,Li Hailong,Guo Haijun,Chen Xuefang,Chen Xinde 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.9
The physical and chemical properties of gold promote its application, such as in the high-tech, electronic products, and aerospace industries. The easily leachable ore is gradually depleted. Thus, it becomes necessary to extract gold from other resources such as refractory ore and electrical and electronic equipment. The normal method of leaching for gold is cyanide leaching, but it is very dangerous for both environment and operator. Non-cyanide leaching methods, including thiourea leaching, halide leaching, and sulfate leaching have been developed to substitute cyanide leaching. A variety of methods to enrich gold from leaching solutions are described in this paper, including solvent extraction, electrowinning, activated carbon adsorption, and ion exchange resins. Among those methods, ion exchange resins can adsorb gold with high adsorption efficiency and regenerate easily as well. This paper focuses on the research progress of the recovery of gold from non-cyanide leachates by ion exchange resins, summarizes the existing resin types and elution processes, points out the limitations in the application of current ion exchange resins, and discusses possible solutions.
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Stable Sheet-Beam Transport in Periodic Nonsymmetric Quadrupole Field
Zhanliang Wang,Yubin Gong,Yanyu Wei,Zhaoyun Duan,Huarong Gong,Zhigang Lu,Lingna Yue,Hairong Yin,Jin Xu,Yuanbao Li,Pukun Liu,Gun-Sik Park IEEE 2010 IEEE transactions on plasma science Vol.38 No.1
<P>Stable sheet electron-beam transport is critical for sheet-beam microwave device which is attractive for high-power millimeter wave to terahertz-regime radiation. This paper studies the stable sheet-beam transport in periodic nonsymmetric quadrupole field. First, the conditions for stable round- and sheet-beam transport in periodic magnetic quadrupole field are deduced. In the deduction, we find that the symmetric quadrupole field and the space-charge field of sheet beam are not well matched. In order to settle this problem, we use periodic nonsymmetric quadrupole field instead of periodic symmetric quadrupole field to transport sheet beam. Finally, 3-D PIC simulations verify the conditions for stable sheet-beam transport and show that periodic nonsymmetric quadrupole field is intrinsically well suited for sheet-beam transport.</P>
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