바울해석의 출발점에 관한 논의 : 하나님 중심, 그리스도의 중심의 구속사적 종말론 Theocentric, Christocentric, Redemptive Eschatology

강혜란 한세대학교 1996 敎授論叢 Vol.9 No.-

복합유기용제 장기 노출자들의 골수충실도 평가를 위한 자기공명영상의 계량적 활용

정해관,최대섭,박건욱,윤환중,김정란,하경임,양승오,김양호 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.2

목 적 : 자기공명영상은 골수의 지방세포와 조혈세포간의 분퐁 차이를 신호강도 차이로 구분할 수 있어 골수 충성도에 대한 평가가 가능하다. 저자들은 유기용제에 장기간 노출된 조선업체 도장공 및 대조군을 대상으로 비참습적인 방법으로 골수 충실도를 평가하는 도구를 개발하기위하여 본 연구를 시행하였다. 방 법 : 1998녀 8월부터 2000년 1월까지 조선소 도장공 중 1개 대학병원에서 유기용제 장기간 사용으로 인한 골수검사 결과 저세포성 골수로 진단 받은 환자 6명(남자 5명, 여자 1명; 평균연령 환자군 46.5세)을 대상으로 말초혈액이 혈액학적 검사, 골수검사 및 요추부 자기공명영상을 실시하였다. 대조군으로는 동일 병원에서 요추부 자기공명영상을 촬영한 환자 132명(남 67명, 여자 65명, 연령 평균 42.5세, 범위 30-59세)을 선정하였다. 요추부 자기공명영상은 T1 및 T2 강조영상의 시상 단면에서 제 12 흉추부터 제 1 천추사이의 추체에서 각반드시 신호강도를 기록하였다. 기준 부위로는 동일 단면의 척추주위근 및 지방조직의 산호강도를 이용하여 각 부위에서 측정한 신호강도를 나누어 골수 신호강도지표를 구하였다. 결 과 : 환자군의 골수 충실도는 20.33-33.6 %이었고 혈액검사상 백혈구수는 2,100-7,600/㎣이었다. 환자군과 대조군 모두에서 각 지표는 제 12흉추에서 아래로 내려갈수록 점차 감소하였다가 제 4 요추 이후 다시 증가하는 양상을 보였다. 환자군과 대조군간의 골수 신호강도지표를 비교하였을 때 T1 강조영상에서 척추주위근을 기준으로 한 골수 신호강도지표가 환자군과 대조군간의 차이를 가장 잘 반영하였으며 환자군이 모든 추체에서 유의하게 높았다. (p<0.05, p<0.01). 대조군의 골수 신호강도지표는 T1 강조영상이 척추주위근을 기준으로 측정하였을 때 여성에서 연령 증가에 따라 모든 측정점에서 골수 신호강도지표는 증가하는 양상을 보였으며 30대와 50대간의 차이는 유의하였다. (p<0.05, p<0.01). 성별에 따른 골수 신호강도지표는 근육을 기준으로 한 골수 신호강도지표에서는 보이지 않았으나 비장을 기준으로 한 골수 신호강도지표는 남녀간에 유의한 차이를 보였다. (p<0.05). 다변량 선형회귀분석에서 연령 및 성별을 보정하였을 때 T1 강조영상의 근육을 기준으로 한 골수 신호강도지표는 환자군에서 대조군에 비하여 제 1 천추에서 0.364 더 높았다. 제 1 천추의 T1 근육을 기준으로 한 골수 신호강도지표의 연령 성별 평균+1 표준편차를 기준으로 하였을 때 6명 중 5명이 그 이상이 분포를 보여 두 군간의 차이가 가장 뚜렷하였다. 결 론 : 저자들은 자기공명영상을 이용하여 골수 충실도를 평가하기 위한 지표를 개발하였고 정상 참고치를 제시하였다. 골수 신호강도지표는 지방조직 함량, 골밀도함께 칼슘 등의 영향을 동시에 반영하지만 이러한 영향을 적절히 보정할 경우 고위험집단에서 골수 충실도를 평가하는데 활용할 수 있음을 확인하였다. 보다 좋은 지표의 개발을 위하여 충분한 표본수를 가진 저세포성 골수 환자집단을 대상으로 후속연구를 수행할 필요가 있다. Objectives : To develop a quantitative and noninvasive method of bone marrow cellularity evaluation in solvent exposed painters. Methods : Six painters (mean 46.5 years, 5 males and one female with hypocellular marrow, and 132 controls were examined using magnetic resonance imaging (MRI). A full examination of the peripheral blood and a bone marrow biopsy was done on each patient. Signal intensities were measured at the vertebral bodies from T12 to S1 on both the T1 and the T2-weighted image (T1WI and T2WI). Signal indices were calculated by dividing the signal indeces of the vertebral bodies by that of the paraspinal muscle and the subcutaneous fat in the same view. Results : The Bone marrow cellularities of the cases painters were between 20.3 % and 33.6 %. Signal indices based on the muscle at T1WI were greater in the cases of the painters compared to those of the controls (p<0.05, p<0.01). Signal indices based on the muscle at T1WI were significantly higher in older women compared with men (p<0.05). After adjusting for age and gender, the signal index of cases at S1 based on muscle of T1WI was higher than that of the controls by 0.364. Five of the six cases had a muscle signal index at S1 of T1WI higher than the mean + 1 standard deviation for the same age group and gender. Conclusions : MR signal indices are influenced by constitutional factors such as fat content. bone density, and the presence of other pathology. However, after adequate adjustment, it can be used as a useful indicator of bone marrow cellularity in a high-risk population.

세포브러쉬와 면봉도말법에 의한 부인과 세포학적 검사의 효율비교

김정란,김성숙,배한익,김용탁,심재철,임문환,윤혜원,이상식 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

A study was undertaken to evaluate the efficiency of the sytobrush compared with the cotton swab for obtaining cells from the uterine cervix. In 300 patients, the cytobrush technique was employed and in control 300 patients was smeared by the cotton swab. In 12 out of 300 patients(4%) endocervical cells were found on the cotton swab technique. A total of 252 out of 300 cytobrush sampler specimen(84%) contained endocervical cells. With the X²method for statistical comparison, the difference in endocervical cell yield between the cotton swab and the cytobrush sampler was significantly different(p<0.01). This was particularly true in older patients. We conclude from study that the cytobrush sampler is of value for obtaining as adequate cervical cytologic specimen.

알레르기 환자에서 MAST-CLA 검사의 의의

남해선,황규윤,,백병준,정윤영,오천환,조성란,박준수 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

To evaluate usefulness of application of MAST-CLA to indetify allergens, authors conducted MAST-CLA allergen-specific IgE assay and collected allergy related symptoms in 118 allergic patients diagnosed at Soonchunhyang University Chunan Hospital during October 1998 through January 2000. The results were as followings; 1. The mean (SD) age was 23.1 (±12.17) years old and teenagers accounted for 33.1% of patients. 2. The frequent allergic symptoms were sneezing (59.3%), rhinorrhea (53.4%), nasal stiffness (44.1%), itching sensation (24.6%), cough or sputum (16.1%), and eye symptom (8.5%) in order. 3. Among these subjects, 62.7% of patients revealed at least more than one specific allergen and 70.3% showed elevated total IgE levels by MAST-CLA. The three most frequent specific allergens were Dermatophagoides farinae (47.5%), Dermatophagoides pteronyssinus (45.8%), and house dust (30.5%). 4. While age was not significantly related to positive of both specific allergens and total IgE (P>0.05), sneezing and nasal stiffness were significantly associated with positive of specific allergen and total IgE, respectively (both P<0.05). 5. Total IgE increased with the number of specific allergens, but both specific allergen and total IgE were not significantly related to increases of allergic symptoms (P>0.05). In conclusion, our data suggest that MAST-CLA allergen-specific IgE assay is useful measure for identification of causative allergens in allergic patients, however, it is recommended that more specific allergic antigens should be determined and replaced or added to Korean inhalent panel of MAST-CLA.

로마서 구조의 재구성 : 롬5장 12-21절의 위치와 관련해서

강혜란 한세대학교 1997 敎授論叢 Vol.10 No.-

바울의 "아담"전승 해석에 대한 연구 : 로마서 5장 12-21절을 중심으로 Romans. Ch. 5:12-21

강혜란 한세대학교 1995 敎授論叢 Vol.6 No.-

동국의대에서 실시한 2002년 전염병관리실무과정에 대한 평가

방미란,임현술,정해관,한영란,정철 대한보건협회 2003 대한보건연구 Vol.29 No.1

Communicable diseases have recently reemerged, with new communicable diseases continually breakmg out on a global scale; threaten the health and economics of populations. The Korean National Institute of Health carries out Field Management Training Prcgrams (FMTP) to address this problem The objectives of this study were the evaluation of the understanding and satisfaction for this program, and recommendation for improvement strategies. We conducted a questionnaire survey of 80 persons who completed the FMTP, at Dongguk University, between March 1 and November 30, 2002. The data collected was analyzed by Student s t-statistics. The understanding of the curriculum was Well in 42 (52.5%) and Moderate in 24 persons (30.0%). The satisfaction with the curriculum was Moderate in 38 (47.5%) and Good in 30 persons (37.5%). The satisfaction for the period of education was Bad for 31 persons (38.7%), which accounted for the majority of cases. The mean scores, by Likert s scale, for the understanding and satisfaction of the curriculum were 3.70 (±0.71) and 3.32 (i0.721, respectively. The mean score for the epidemiological survey was the highest for satisfaction with the course, at 3.78 (±0.62). The mean value of satisfaction for curriculum in education of period was significantly higher in health department group than in nursing department group (P<0.05). From this survey it appears the respondents were satisfied with this program. The FMTP will be systematically revised for curriculums, and effort will be required to develop controls for communicable disease, both by the government and the university.

산상수훈 연구 : “염려에 대한 교훈” (마 6:25-34)의 주석적 연구 An Exegetical Study on "Exhortation about Worry"(Mat. 6:25-34)

강혜란 한세대학교 1994 敎授論叢 Vol.5 No.-

17세기 조선의 규방 현실에 대한 보고(報告)

조혜란 한국고전연구학회 2003 한국고전연구 Vol.9 No.-

This essay is a report about the lives of noble class women in the 17th century of Chosun dynasty. To get close to the lives of noble class women in the 17th century, the perosnal collections of works at <Han-guk-mun-jip-choung-gan(韓國文集總刊)> were examined. The number of the writers lived in the 17th century was 65 persons, the articles reach 386 pieces. And most articles about women were written after their death to praise their virtues. This essay could make an offer menaingful data to understand the old novels of the 17th century of Chosun dynasty. It is because that the ternimology ′Gyu-bnag-susul(閨房小說)′, and the works named ′So-hyun-seong(蘇賢聖錄)′were closely related to the 17th century. For concrete understanding the terminology ′Gyu-bnag-susul(閨房小說)′, the works as ′Sa-ssi-nam-jeong-gi(謝氏南征記)′ and ′So-hyun-seong(蘇賢聖錄)′ or understanding the enforcement of the Confucian patriarchy, the study of lives of nobel class women in the 17th century needs to be preceded. This essay was started by this kind of critical mind. As a result, I could find some characteristics, ′Gyu-bang(閨房) of the 17th century′ were not a close space at all. Married women still kept strong relations with the parent′s home and visited each other. And the women had to carry out several roles. Among those roles, there were some tasks to manage economic problems and keep daily lives. These facts are expected to become a criteria to understand the old novels in the 17th century of Chosun dynasty. To better date, comparisons the articles of the 17th century with those of the 18th and 19th centuries will be followed.

새 천년 시대를 위한 로마서 해석의 전망

강혜란 한세대학교 1999 敎授論叢 Vol.15 No.-