층수돌기 방선균증 : 1예 보고

이범하,이혜경,박성진,차장규,김희경 순천향대학교 의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.2S

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간접 분광광도 검출법을 이용한 비발색 음이온들의 액체 크로마토그래피

吳海範,郭皇來,李承錫 又石大學校 1991 論文集 Vol.13 No.-

The separation of non-chromophoric anions were studied on the ion-cxchange chromatography method by HPLC.a-Naphthalenesulfonic acid(α-NS) was used as a visualization agent as well as ion-exchange agent in this experiments by indirect photometric detection method. Also, several factors affecting to the retention time and the separations of samples were investigated. And, the following results were obtained in this study. 1. These non-chromophoric anions were detected by the indirect photometric detection method at the 285nm for α-NS 2. The capacity factor of samples was influenced by the concentration of α-NS and the strength of organic solvent. 3. Some mixtures of samples were able to separated with good resolution and relatively high sensitivity providing detection limit of 0.1㎍ under optimum condition.

2차원 및 3차원 초음파를 이용한 태아표면의 해부학적 선별 검사에 관한 연구

윤석범,이해혁,이정재,최경훈,이순곤,이임순,이권해 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Objective : Our purpose of this study was to determine the clarity and consuming time of fetal surface screening in thirty-eight fetuses from 24 to 32 weeks of gestation by use of two and three-dimensional ultrasonography. Methods : From May 1998 to July 1998, we performed the fetal surface screening of the fetal face, extremities, and spine. Thirty-eight fetuses of 24-32 weeks of gestation (thirty-seven normal fetuses and one abnormal fetus) were studied by use two-dimensional (AI 5200S, 3.5-5.0MHz; Acoustic Imaging Technologic Cooperation, U.S.A.) and three-dimensional ultrasonography (Volusion 530D, 3.5-5.0 MHz ; Kretz-Medicine, Korea). On the fetal face, we evaluated both orbits, nose, lips and brow. Both hands and feet, five digits and toes should be seen in this study. We evaluated cervical spine and lumbosacral junction of the spine. Results : The maternal average age of 38 patients was 29.9 years and the average gestational age was 29.7 weeks. The results of fetal surface screening were as follows : face (both orbits 89.5%, lips 92.1%, nose 92.1%, and brow 89.5%), extremities (both hands 68.4% and feet 73.7%), and spine (cervical spine 94.7% and lumbosacral junction 97.4%) by use of two-dimensional ultrasonography. By use of three-dimensional ultrasonography, results were as follows : face (both orbits 76.3%, lips 81.6%, nose 81.6%, and brow 78.9%), extremities (both hands 76.3% and feet 78.9%), and spine (cervical spine 71.1% and lumbosacral junction 73.7%). Consuming time for two-dimensional ultrasonography were 4.7 minutes for face, 11.6 minutes for extremities, and 5.7 minutes for spine. Using three-dimensional ultrasonography results were 12.8 minutes for face, 17.9 minutes for extremities, and 11.7 minutes for spine. Average consuming time of all fetal anatomic screening was 22.0 and 42.4 minutes by use of two and three dimensional ultrasonography. In one abnormal fetus had cleft lip and polydactyly of right foot which were detected all by three-dimensional ultrasonography, but we couldn't detect the polydactyly by two-dimensional ultrasonography. Conclusion : Three-dimensional ultrasonography was more time-consuming method, but we suggested that three-dimensional ultrasonography was superior than two-dimensional ultrasonography in fetal surface screening.

군항공기사고조사에 관한 연구

김해마중,하홍영,홍상범 한국항공우주법학회 2003 한국항공우주정책·법학회지 Vol.18 No.-

군항공기사고조사의 전문성과 독립성을 제고하기 위하여 상설사고조사기구를 신설하여야 한다. 상설조사기구를 신설함으로써 조사기구의 위상을 높이고 조사의 신뢰성을 확보할 수 있다. 민과 군이 모두 관련된 사고조사 시 민과 군의 조사권한의 주체, 업무협조 등에 관한 규율이 부재하고 있으므로 이를 입법화해야 한다. 군과 관련된 민항공기 사고조사 시 군의 전문가들이 참여함이 바람지하다. 조사의 실효성 보장을 위하여 항공사고에 대한 정보를 직접 수집하는 조사관의 활동을 보장하는 규정을 마련해야 한다. 또한, 사고조사의 목적은 오직 사고예방에만 있으므로 정보의 공개범위를 제한하고 조사결과를 형사절차나 징계절차에서 사용할 수 없도록 하여 조사의 객관성을 확보해야 할 것이다. In an effort to enhance the independence of and expertise in military aircraft accident investigation, a permanet accident investigation board should be established. Estabilishing permanent accident investigation board would render the military accident investigation more reliable and would increase its public esteem. Because there is no provision governing the responsibilities of theinvestigation and cooperation between civil and military authority in case that both civil and military aircraft are involved, it is necessary to fill this gap by enacting appropriate laws. In case of civil aircraft accident investigation involving a military issue, it would be better to allow military authority to be involved in the investigation. For the betterment of investigation, it is also necessary to provide a field investigator an authority to directly coolect relevant information. Since the sole purpose of accident investigation is to prevent the recurrence of aircraft accidents, the scope of information disclosure should be limited and the investigation report shall be used for neither criminal procedure nor disciplinary procedure so that the objectivity of the investigation should be ensured.

이온쌍 크로마토그래피에 의한 벤젠슬폰산과 그 유도체들의 분리

吳海範 又石大學校 1985 論文集 Vol.7 No.-

Dodecyltrimethylammonium bromide (DTAB) was examined as a counter-ion in the separation of aromatic sulfonic acids on alkylmodified silica (ODS) column by reversed-phase ion-pair chromatography. The capacity factor of acids was investigated and separation was attempted. The capacity factor of samples was influenced by the several factors such as a concentration of counter-ion, concentration of methanol, kinds and concentration of electrolyte in mobile phase as well as kind and position of functional group in samples, Some mixtures of samples were able to be separated under optimum condition.

정신분열병 환자에서 통계적 확률 해부학 지도를 이용한 확산텐서영상 연구 : 겉보기 확산 계수 지도를 이용한 고찰

홍순범,신용욱,김대진,문원진,정은철,이재성,박해정,권준수 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

Objectives : Diffusion tensor imaging (DTl) studies of schizophrenia, thus far, have mainly focused on white matter abnormalities reflected in anisotropy indices such as fractional anisotropy (FA), but recently, new implications of apparent diffusion coefficient (ADC) have been proposed. This is. to our knowledge, the first study to analyze ADC maps of schizophrenic Patients using statistical parametric anatomical mapping (SPAM). Methods : DTl was performed in 20 schizophrenic patients and an equal number of age- and sex-matched healthy controls. ADC maps were then generated, from which 98 volumes of interest were extracted using SPAM. Probability-weighted mean values of ADC were calculated from each volume of interest and compared between the two groups. Results : Significantly higher mean ADC values were observed in patients with schizophrenia compared to healthy controls in the following volumes of interest: bilateral hippocampal formation, bilateral uncus, nght thalamus, light temporal lobe white matter, right superior temporal gyrus, bilateral insula and right lateral ventricle. Conclusion : The results support the recently proposed assertion that regionally increased ADC may reflect cortical brain atrophy. In addition, a new possibility is raised that a neuropathological event involving both the gray and the white matter may also play a role.

Sonographic and Clinical Findings of Surgically Managed Small Bowel Intussuception

홍현숙,이범하,박성진,이해경 순천향의학연구소 2010 Journal of Soonchunhyang Medical Science Vol.16 No.1

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비장경색이 동반된 쯔쯔가무시병 1예

오종찬,이범주,장재현,원경준,박경희,김동민,박치영,정춘해 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Tsutsugamushi disease is an acute febrile illness caused by Orientie. tsutsugsmushi. It is characterized by fever, myalgia, lymphadenopathy, and rash. And it can be easily diagnosed by characteristic eschar and serologic testing. Nearly all of the patients with tsutsugamushi disease improve with antibiotics such as doxycycline. However, the fatality rate of untreated cases is seven to ten percent. Splenic infarction is not common disease which is caused by occlusion of the main splenic artery or any of its branches. It is mainly caused by emboli that arise from cardiovascular disease, but sometimes by regional thrombosis associated with leukemia, myeloproliferative disorder, sickle cell anemia, pancreatitis, splenic torsion and septicemia. We experienced one case of tsutsugamushi disease with splenic infarction, which was improved after doxycycline treatment finished.

비행안전구역 밖에서의 고도제한

하홍영,김해마중,홍상범 한국항공우주법학회 2003 한국항공우주정책·법학회지 Vol.18 No.-

군용항공기지법은 비행안전구역을 설정하여 각 구역별 표면높이 이상의 장애물 설치를 금지하고 있다. 비행안전구역은 항공기의 비행안전을 확보하기 위해서 설정된 것이다. 그러나, 우리의 경우 좁은 국토여건을 감안, 비행안전구역을 6구역까지만 축소 설정하여 계기비행절차와 관련된 비행안전상의 문제점이 있다. 계기비행절차가 수립되어 있는 영역 중 일부에 대하여는 비행안전구역이 설정되지 않아 아무런 고도제한을 가할 수 없는 것이다. 본고에서는 이러한 문제인식을 출발점으로 삼아, 비행안전과 관련된 비행안전구역 외곽에서의 고도제한 문제를 다루고 있다. 우선 군용항공기지법상의 비행안전구역과 각 국의 비행안전구역 설정 현황을 검토하였다. 이를 토대로 현행법이 안고 있는 문제점을 논의하였다. 문제점을 해결하기 위해서는 비행안전ㄱ역 밖의 일정 영역에 대하여도 고도제한을 할 필요성이 있다. 가장 바람직한 방안 검토를 위해 비행안전구역 밖에서도 고도제한에 대한 입례법을 참조하였다. 그 결과 여러 가지 입법안을 상정해 볼 수 있었고, 비행안전구역 밖의 일정 부분에서 일정 높이 이상의 건축을 허용하기 위해서는 비행안전심사를 거치도록 하는 것이 가장 바람직하다는 결론을 내려보았다. The Military Air base Law has designated imaginary surface, restricting the height of structure above the imaginary surface. The purpose of establishment of imaginary surface is to promote safety of aircraft operation. However, given the fact that the land is limited, the Military Airbase Law does not set up outer horizontal surface such that the reduced imaginary surface would undermin the safety of aircraft operations with respect to IFR (Instrument Flight Rules) procedures. The fact that some areas which IFR procedures require are not designated as imaginary surface results in no imposition of height restriction on such area. With regard to aviation safety, this article deals with issue of height restriction on area which is beyond the imaginary surface area. This article also examines the establishment of the imaginary surface in the Military Airbase Law, and conducts case study of imaginary surface systems in other country. Based upon this discussion, the current problems posed in the Military Airbase Law will be discussed. To resolve these problems, it is necessary to establish height restriction zone beyond the current imaginary surface area. The provisions of ICAO, FAA and other counties in relation with this issue are referred as well. As a result, many different proposals are suggested, and it is concluded as the most effective proposal that, in certain zone beyond the imaginary surface area, an aeronautic study should be required for the purpose of ensuring aviation safety before a permit of construction higher than prescribed height is issued.

4,5α-epoxy-3,6-dimethoxy-α-n-butyl-α,17-dimethyl-6,14-ethenomorphinan의 합성에 관한 연구

정순량,김근재,오해범 又石大學校 1983 論文集 Vol.5 No.-

Conformation with a hydrogen bond between the C_6 methoxyl and C_19 hydroxyl group among Diels-Alder adducts of thebaine and thebaine derivatives makes the molecule more rigid. To examine this hypothesis, new compound eliminated the intramolecular hydrogen bonding as a factor in determining the active conformation of the alkyl chain were available. A compound which the C_19 hydroxyl group has been replaced by a hydrogen has been synthesized as follows: Thevinone 3 has been prepared from thebaine by means of Diels-Alder reaction. Primary alcohol 7 has been prepared from Ketone 3 via epoxide 5 and aldehyde 6. This alcohol 7 underwent reaction with mesyl chloride to afford mesylate 8. Further reaction afforded 4, 5 α-epoxy-3, 6-dimethoxy-α-n-butyl-α, 17-dimethyl-6, 14-ethenomorphinan by displacement with propyl lithium cuprate.