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        • KCI등재

          중국 채소류 생산 관리체계 분석 -산동지역 고추, 마늘, 양파 농가 사례조사 결과-

          하두종 ( Doo Jong Ha ),유창환 ( Chang Whan Yu ),최칠구 ( Chil Ku Choi ),조성주 ( Sung Ju Jo ),이종수 ( Jong Zhu Li ) 한국국제농업개발학회 2015 韓國國際農業開發學會誌 Vol.27 No.5

          1. 본 연구는 중국 산동성의 평도시(平度市) 및 신강성 집단재배농장을 대상으로 주요 채소 농산물인 고추, 마늘, 양파에대하여 한국과 중국의 생산 관리체계 및 기술 수준을 비교ㆍ분석하였다. 2. 고추의 경우 한국은 묘를 구입하여 정식하는 비율이 높지만 중국은 대부분 자가 채종 후 자가 육묘를 하는 체계이다. 가장 특징적인 것은 한국은 수확을 10일 간격으로 5 ~ 6회 하지만, 중국은 일시 수확하여 수확노동력을 줄이고 있다. 고추의 경영비와 생산비 비교에서는 각각 한국이 3,975원/kg,11,686원/kg이며, 중국은 519원/kg, 1,895원/kg으로 한국의 경영비가 7.3배, 생산비는 6.2배 차이가 나는 것으로 조사되었다. 3. 중국의 마늘 파종량은 한국에 비해 3배 이상으로 밀식파종을 한다. 재배 이랑은 한국은 넓은 이랑이며, 중국은 2줄 좁은 이랑에서 재배 하고 있다. 멀칭은 한국이 기계멀칭을 64%하고 있으나 중국은 인력을 이용한 멀칭을 하고 있다 마늘의 경영비와 생산비 비교에서는 각각 한국이 1,128원/kg, 2,049원 /kg이며, 중국은 310원/kg, 686원/kg으로 경영비는 3.6배, 생산비는 3.0배 차이가 나는 것으로 분석되었다. 4. 양파는 중국이 한국보다 경지기반은 좋으나 호당 경지면 적은 0.14 ha로 매우 영세하다. 한국은 복비와 유기질 비료를 사용하고 방제를 3 ~ 5회하는 반면, 중국은 계분을 사용하고, 살균, 살충, 제초 방제는 1회만 실시하고 있다. 육묘는 중국과 한국이 모두 구입종자를 이용한 자가 육묘를 하는 동일한 생산체계이다. 양파의 경영비와 생산비 비교에서는 각각 한국이 199원/kg,334원/kg이며, 중국은 46원/kg, 98원/kg으로 한국보다 경영비는 4.3배, 생산비는 3.4배 차이가 있은 것으로 나타났다. This study was carried out to analyze the Chinese vegetable production system and to compare it with the adopted system in Korea. Farm producing pepper, garlic and onion in Sandong and Singang were surveyed. For pepper production, Korea farm purchased the planting materials while, China farm produced their own seeds and seedlings. Also, the most significant difference was the one time harvesting in China, while Korea usually harvests 5 ~ 6 times within 10 days term per year with an increase in production. The management and production cost were observed to be 3,975 won/kg, 11,686 won/kg for Korean pepper, but China has low cost by 519 won/kg, 1,895 won/kg. An amount of garlic seed in China was more than three times that of Korea. Korea covered the wide furrow with mulching plastic and used machines that raised the production rate by 64%. However, Chinese depends on the human labor and make narrow furrow to increase the productivity. The management and production cost were 1,128 won/kg, 2,049 won/kg for Korean garlic, while China has low cost by 310 won/kg, 686 won/kg respectively. To cultivate onion, the land condition of China was better than Korea having an average farm size of 0.14 ha smaller than Korea. Two nations were compared having the same seedling production system that buy the seed at the market and seedling their own land. Likewise, the management and production cost observed as 199 won/kg, 334 won/kg for Korean onion, while Chinese cost was lower by 46 won/kg, 98 won/kg. It is concluded that the good producing system of China such as pepper one-time harvesting system should be adopted to korean farm system to reduce cost.

        • KCI등재

          응급실에서의 확산강조 자기공명 영상

          정성필,이석우,양영모,하영록,김승환,유인술 대한응급의학회 2001 大韓應急醫學會誌 Vol.12 No.3

          Background: This study was designed to review the cases of patients who had undergone diffusion-weighted magnetic resonance imaging(DWI) in the emergency department(ED), and to investigate its clinical usefulness and current indications. Methods: We analyzed the cases of 152 consecutive patients who underwent DWI in the ED from Jan to Mar 2001. DWI was obtained with the use of a multislice, single-shot, spin-echo plana imaging technique(GE SignaR). Imaging time was less than one minute. The medical records, the DWI films and the computed topography results were reviewed. We investigated the chief complaint, initial findings of physical examination, final diagnosis, decision-making department, interval from admission to imaging, and DWI findings. Results: DWI showed positive findings of high signal intensity in 84 patients(55.3%). Among the 68 patients who yielded a negative result, false negative occurred with 12 patients(17.6%): 10 lacunar infarctions, a pons infarction, and a brainstem infarction. Eleven patients were determined as having a cerebral hemorrhage, all of whom showed the abnormal finding of a mixed signal in DWI. The sensitivity and the specificity of DWI to rule out stroke were 85.5% and 98%, respectively. Current indications for DWI in our ED are age older than 60, alert mental status, and one of the symptoms or signs among lateralyzing sign, language disturbance, and dizziness/vertigo. Conclusion: DWI was highly specific to rule out stroke, so emergency care professionals should be familiar with this new technology. Further prospective study is required to determine the proper indications and clinical usefulness of DWI in the ED.

        • 大學 敎養體育 改善方案 硏究

          金永煥,河永俊,文成喆 仁荷大學校 스포츠科學硏究所 1990 論文集 Vol.2 No.-

          The purpose of this study is plan improvement for General Physical Education. The subjects of questionnaire are student of college, director of company and college all over the country. There are two aspects for improvement plan of General Physical Education by curriculum and education environment . 1, The improvement plan for general physical education The purpose of general physical education in college are as follows : (1) Education for independence. (2) Education for devotion to the welfare of mankind. (3) Education for leadership. (4) Education for service of democracy development. (5) Education for ideal realization of mankind. 1) The aspect of curriculum (1) The end of instruction (1) Education for fitness (2) Education for team-work (3) Education for motor-skill (4) Education for body-balance (5) Education for leadership of sports for all (2) The contents of instructions (1) Student can chose an event a) An events of lifetime sport; swimming, Tennis, Bowling, Table tennis, Fencing, Ski Shooting, Basket ball, Golf, Archery, Riding, etc. b) An events of official sport; Soccer, Volley ball, Basket ball, Table tennis, Base ball, Climbing, etc. (2) Set up of instruction for season and intensive course. (3) Management of practical instruction of 3 grade. 1- For fitness. 2- For technique of personal and team. 3- For game management (4) Domain of Sports Science are as follows: (a) Physical Education for man's life. (b) Play, Game, Sports. (c) Recreation. (d) Physical Education for health. (e) Sports physiology. (H) Sports amatomy and Biomechanics. (g) Sports psychology. (h) Sports sociology. (i) Fitness (j) Team-work (k) Body-blance (l) Game rule (3) The method of instruction (1) A class compose less than 40. (2) Students wear sports uniform when practical instruction. (3) Students prepare instrument for practical instruction but expensive instrument lead or aid by authority (4) Students prepare textbook. (5) A supporting instrument for practical instruction prepare as follows. (a) Instrument for audiovisual. (b) Instrument for evaluation and measurement. (c) Instrument for supporting of playing. (e) Utilization of assistant teacher for practical instruction (4) The evaluation of instruction (1) Evaluation time is to be measured at any time, midterm and term examination by items. (2) Evaluation item are as follows? (a) Technique ability. (b) Presense and absense matters. (c) Written examination and report. (d) Attitude for research , (e) Readness of sports uniform and instrument (f) Fitness. (g) Team-work. (h) Body-balance. (i) Independence. (j) Service ship. (3) Reference of mark by each other measure of students-team-work, independence, service-ship 2) Aspect by education environment (1) College rule (1) General physical education is to be considered as required subject (2) Term of general physical education is from 2 to 4 semester. (2) An instrument and institution (1) Gymnasium (2) Instrument for practical instruction (3) Supporting instrument (a) Audiovisual for practical instruction (b) Instrument for evaluation (Motor skill and Fitness) (c) Instrument to support of playing. (4) Aid to use of private possessions. (3) Improvement of management post for, general Education (1) Subdivision and Specility of management post. (2) Manage to control fitness all through life. (3) Management of personal data room.

        • KCI등재

          넙치 (Paralicthys olivaceus) 치어용 배합사료에 콩비지 첨가가 성장 및 체성분에 미치는 효과

          이상민,김경덕,장현석,이용환,이종관,이종하 한국수산학회 2003 한국수산과학회지 Vol.36 No.6

          This study investigated the effect of soybean-curd residues as an ingredient of the formulated diet for juvenile flounder (Paralichthys olivaceus). Three replicates of juvenile fish (averaging weight 1.5 f 0.04 g) were fed one of four isonitrogenous (50%) diets containing O%, 5%, 10% and 15% soybean-curd residues for 7 weeks. Survival, hepatosomatic index and condition factor of the fish were not affected by dietary soybean-curd residues levels. Weight gain, feed efficiency and protein efficiency ratio of the fish fed the diet containing 5% soybean-curd residues were not significantly different to those of the fish fed the control diet, however these values decreased in the fish fed the 10% and 15% soybean-curd residues (P<0.05). Daily feed and protein intake increased with increasing dietary soybean-curd residues level. Crude protein and lipid contents in the whole body decreased with increasing dietary soybean-curd residues, but no significant differences were observed among control, 5% and 10% soybean-curd residues diets (P>0.05). Plasma total protein concentration of fish was affected by dietary soybean-curd residues levels (P<0.05). It is concluded that the soybean-curd residues as a substitute for wheat flour can be included up to 5% in the diet for juvenile flounder.

        • 탈지 환원유에서 Bifidobacterium longum의 호기성 고농도 배양에 관한 연구

          구동환,하상우,조수현,박기문,김동운,강국희 성균관대학교 생명과학자원연구소 1997 生命資源科學硏究 Vol.4 No.1

          The objectives of this study were to investigate the optimal condition for growth and highly concenterated culture of Bifidobacterium longum (Bif longum). The effects of additives were compared with titratable acidity and viable cell counts, and 10% reconstituted skim milk (no additive) was used as a control. Correlation coefficient for the growth of Bif. longun between CO_2 anaerobic jar method and overalaid medium method was R=0.99. When 1% Bif. longurn was inoculated on 12%, 14%, and 16% reconstituted skim-milk, viable cell counts were 8.60, 8.89, and 8.93 Log CFU/ml, respectively. When Lactose, Glucose, Glucosamine, Fructose, Peptone, N-acethyl-D-glucosamine, D-galactose, and liver extract were added to 16% reconstituted skim-milk, the viable cell counts were 8.61, 9.05, 9.15, 9.24, 8.82, 9.75, 9.17, and 9.64 Log CFU/ml, respectively. Therefore, D-galactose, liver extract, and N-acethyl-D-glucosamine were selected as final additives. When Bif longum was inoculated on Fermentor-I (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% D-galactose and 0.5% liver extract), Fermentor-II (16% reconstituted skim milk containing 0.190% yeast extract, 0.590% N-acethyl-D-glucosamine and 0.5% liver extract), Batch culture-I (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% D-galactose and 0.5% liver extract), and Batch culture-II (16% reconstituted skim milk containing 0.1% yeast extract, 0.5% N-acethyl-D-glucosamine and 0.5% liver extract), viable cell counts were 10.46, 9.37, 9.03, and 8.83 Log CFU/ml, respectively. Although liver extract was the important additive for the highly concentrated culture of Bif. longum in this study, it caused serious off-flavor when liver extract-1 (contained cell mass) was added to Fermentor culture. However, flavor was improved when liver extract-2 which was removed cell mass, was used instead of liver extract-1. Addition of 2% liver extract-II and 1% D-galactose had the similar effect with addition of 0.5% Liver extract-I and 0.5% D-galactose on the growth of Bif. longum.

        • KCI등재

          체외 방사선조사시 인체 말초혈액 임파구의 염색체이상 빈도에 관한 연구

          안용찬,하성환 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.2

          급성 전신 및 부분 피폭시 피해자들에 대한 치료방침의 결정에 있어 참고자료로서 사용하기 위하여 저자들은 체외에서 말초혈액을 60 Coγ-선으로 2Gy에서 12Gy까지 방사선 조사하여 말초 임파구에서 관찰되는 염색체이상의 빈도와 방사선량과의 관계를 실험적으로 연구하였다. 관찰된 세포중 불안정 염색체이상(dicentric 염색체, ring 염색체, acentric fragment쌍)이 나타난 세포의 비율은 2Gy에서 32%, 4Gy에서 47%, 6Gy에서 80%, 8Gy에서 94%, 10Gy이상에서는 100%였다. 급성 전신 피폭시 평균 흡수선량을 반영하는 지표인 Ydr은 2Gy에서 0.373, 4Gy에서 0.669, 6Gy에서 1.734, 8Gy에서 2.773, 10Gy애소 3.746 그리고 12Gy에서 5.454였다. 방사선량(D)과 염색체이상(dicentric 염색체와 ring 염색체의 합) 빈도(Ydr)와의 관계는 Ydr=9.322×10- ²/Gy×D+2.975×10-²/Gy²D²로 나타났다. 신체의 부분피폭시의 선량 및 과거의 피폭선량을 계산할 때 사용하는 지표인 Qdr은 2Gy에서 1.166, 4Gy에서 1.436, 6Gy에서 2.173, 8Gy에서 2.945, 10Gy에서 3.746, 그리고 12Gy에서 5.454였다. 이와 같은 선량측정방법의 신빙도를 검증하기 위하여 신체의 부분에 균일한 선량분포의 1.8Gy, 2.5Gy 및 7.0Gy의 방사선치료를 일회 받은 환자들로부터 구한 Qdr은 각각 1.109, 1.222, 2.222였으며 이로부터 Qdr=Ydr/(1-e -Ydr)의 관계식을 이용하여 계산해 낸 피폭선량은 1.52Gy, 2.48Gy 및 6.54Gy로서 실제 조사한 선량과 매우 근사한 결과를 얻었다. As guides to decision-making in the management of the victims in case of acute whole body or partial body radiation exposure, we studied the relationship between radiation dose and the frequency of chromosomal aberrations observed in peripheral lymphocytes that were irradiated in vitro with ??Co γ-rays at dodws ranging from 2Gy to 12Gy. The yields of cells with unstable chromosomal aberrations (dicentric chromosomes, ring chromosomes, and acentric fragment pairs) were 32% at 2Gy, 47% at 4Gy, 80% at 6Gy, 94% at 8Gy, and 100% at 10Gy and over. Ydr, which reflect average dose to the whole body in case of acute whole body exposure, were 1.373 at 2Gy, 0.669 at 4Gy, 1.734 at 6Gy, 2.773 at 8Gy, 3.746 at 10Gy and 5.454 at 12Gy. The relationship between radiation dose (D) and the friquency of dicentric plus ring chromosomes per cell(Ydr) could be expressed as Ydr=9.322×10-²/Gy×D+2.975×10-²/Gy²×D². Qdr, which are used in estimating dose of partial body exposure and dose of past exposure, were 1.166 at 2Gy, 1.436 at 4Gy, 2.173 at 6Gy, 2.945 at 8Gy, 3.746 at 10Gy and 5.454 at 12Gy. To see how confidently this dosimetry system may be used, we obtained Qdr values from those who received one fraction of homogenous partial body irradiation of 1.8Gy, 2.5Gy, and 7.0Gy therapeutically; in vivo Qdr values were 1.109, 1.222 and 2.222 rewpectively. The estimated doses calculated from these in vivo Qdr values using the equation Qdr=Ydr/(1-eYdr) were 1.52Gy, 2.48Gy, and 6.54Gy respectively, which were very close to the doses actually given.

        • KCI등재

          방사선 치료후 시간경과에 따른 염색체이상 빈도의 변화

          송명재,하성환,이춘자,김희근,김미숙 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.1

          임파구의 염색체이상 빈도로부터 피폭자의 흡수선량을 구하는 방법은 사고로 인해 급성피폭을 받는 경우 유용하게 사용될 수 있다. 그러나 방사선 피폭 후 시간이 경과함에 따라 불안정 염색체이상을 가진 임파구는 감소하게 된다. 이에 방사선 치료후 시간 경과에 따른 불안정 염색체이상 빈도의 변화를 규명하고자 한다. 전골반에 50.4 Gy의 방사선 치료를 받은 총 20명의 자궁경부암 또는 자궁내막암 환자를 대상으로 41개의 검체를 얻었다. 채혈의 시기는 방사선 치료후 1일 3주, 6주, 12주, 24주, 52주, 104주, 156주, 208주, 520주로 하였다. 이들 말초혈액의 임파구에 대해 전혈미세배양을 실시한 후 임파구의 불안정 염색체이상을 관찰하여 Ydr, Qdr, Qdra를 얻었다. Ydr 값은 방사선 치료가 끝난 직후부터 3주까지 plateau를 보였고 이후 감소하는 경향이었다. Ydr의 평균값은 치료후 3주에 0.29에서 급격히 감소하여 2년후 0.05로 감소하였으며 이후 5년까지 서서히 감소하였다. 회귀분석을 실시한바 Ydr = 0.259×exp(-0.0429T)+0.0560×exp(-0.00106T)(time in weeks)로 나타났다. Qdr값은 치료 직후부터 24주까지 1.51 전후로 거의 변화가 없었으며 이후 감소하여 52주 이후에는 1.17 전후로 거의 일정하였다. Qdra 값은 치료 직후부터 12주까지 1.10 전후이며 이후 감소하여 52주 이후에는 0.81 전후였다. 피폭 후 시간경과에 따른 Ydr 값의 감소는 두 component exponential 모델을 잘 맞고 이 식을 이용하여 생물학적 선량측정이 가능하다. Qdr 값 및 Qdra 값은 피폭후 시간경과가 짧은 경우 피폭선량을 추정하는 지료로 사용할 수 있다. It is good method to use frequency of chromosome aberration in lymphocytes for a biological dosimetry in cases of accidental exposure to radiation. But in cases of past edposure, biological dosimetry is limited because the friquency of aberration decreases by time after exposure. To provide a basic data for estimationof past radiation exposure, the changing pattern of frequency of unstable chromosome aberration by time interbal after exposure was studied. Observation was made on peripheral lymphocytes of 41 blood samples from 20 patients treated for uterine cervical carcinoma and endometrial caricinoma. The patients received 50.4 Gy radiation to whole pelvis. Elapsed times after the completion of radiation therapy were 1 day, 3, 6, 9, 12, 24, 52, 104, 156, 208, 260 and 520 weeks. All the blood sample were microcultured. The Ydr, Qdr and Qdra were calculated form frequency of unstable aberration. Ydr did not decrease for 3 weeks after radiation therapy, and thereafter, decreased very rapidly and reached 0.05 at two years after radiation therapy and decreased very slowly until 5 years after radiation therapy. Relationship between unstable chromosome aberration and time interval after radiation therapy was described as Ydr = 0.2590.259×exp(-0.0429T)+0.0560×exp(-0.00106T)(time in weeks) Qdr remained constant at 1.51 until 24 weeks after radiation therapy and then decreased to 1.17 at 52 weeks. Therafter, it did not change. Qdra remained constant at 1.10 for 12 weeks after radiation therapy and decreased to 0.81 at 52 weeks. Thereafter, it remanined constant. Two superimposed exponential Ydr disappearance rate wuggests that it is possible to calculate the past exposure dose. When the elapsed time after exposure is short, Qdr and Qdra are useful papameters for biological dosimetry for past radiation exposure.

        • KCI등재후보

          자간전증의 자궁정맥혈장 및 제대정동맥혈장내 항산화능과 항산화 비타민

          김기민,김윤하,안봉환,양성열,김철홍,조문경,송태복 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.4

          목적 : 자간전증시 자궁정맥혈장, 제대정맥혈장 및 제대동맥혈장의 항산화능과 항산화 비타민의 양태를 파악하여 이들이 자간전증시 산모와 태아의 병태생리에 어떤 역할을 하는지 알고자 하였다. 연구 방법 : 임신 34주 이상의 정상 임부 18명과 자간전증 환자 16명으로부터 제왕절개술시 분만전에 자궁정맥혈을 채취하였고, 태아분만시 제대정맥과 동맥혈, 그리고 태반 분만후 자궁정맥혈을 채취하여 혈장을 얻었다. Thiobarbituric acid (TBA)반응을 이용하여 지질과산화물 농도를 측정하였고 Cao 등의 방법으로 항산화능(oxygen-radical absorbance capacity, ORAC)을 측정하였고, high performance liquid chromatography (HPLC)를 이용하여 아스코르빈산 (ascorbic acid), 요산 (uric acid), 레티놀 (retinol), 알파-토코페롤 (α-tocopherol) 및 감마-토코페롤 (γ-tocopherol) 농도를 측정하였다. 결과 : 1. 정상 임신군의 분만전과 분만후 자궁정맥혈장내 지질과산화물은 3.48±0.29와 3.93±0.38 nmol/mg protein이었으며, 자간전증군의 분만전과 분만후 자궁정맥혈장내 지질과산화물은 5.56±0.57과 5.37±0.41 nmol/mg protein으로 자간전증군에서 정상 임신군보다 모두 의의있게 높았다 (p<0.01). 2. 정상 임신군의 재대정맥혈장과 제대동맥혈장내 지질과산화물은 5.18±0.38과 5.14±0.39 nmol/mg protein이었으며, 자간전증군의 제대정맥혈장과 제대동맥혈장내 지질과산화물은 7.32±0.55와 8.21±0.81 nmol/mg protein으로 자간전증군에서 정상 임신군보다 모두 의의있게 높았다 (p<0.01). 또한 자간전증군에서 제대동맥혈장내 지질과산화물이 제대정맥혈장내보다 의의있게 높았다 (p<0.05). 3. 정상 임신군의 분만전과 분만후 자궁정맥혈장내 항산화능은 12596.1±726.1과 11438.9±339.2 U/mL이었으며. 자간전증군의 분만전과 분만후 자궁정맥혈장내 항산화능은 10993.8±622.2와 10651.52±628.1 U/mL로, 자간전증군에서 분만전 자궁정맥혈장내 항산화능이 정상임신군보다 의의있게 낮았으나 (p<0.050, 분만후 자궁정맥혈장내 항산화능은 서로간에 유의한 차가 없었다. 4. 정상 임신군의 제대정맥혈장과 제대동맥혈장내 항산화능은 12804.6±463.7과 13010.1±649.4 U/mL이었고 자간전증군의 제대정맥혈장과 제대동맥혈장내 항산화능은 10515.1±683.4와 11800.0±472.7 U/mL로, 자간전증군에서 제대정맥혈장내 항산화능이 의의있게 낮았으나 (p<0.05) 제대동맥혈장내 항산화능은 서로간에 유의한 차가 없었다. 5. 자궁정맥혈장내 아스코르빈산 농도는 분만전과 분만 후 각각 정상 임신군에서 551.4±57.6와 450.8±33.6 nmol/mL이었고 자간전증군에서 419.2±64.6과 398.1±45.2 nmol/mL로, 자간전증군에서 정상 임신군보다 의의있게 낮았다 (p<0.05). 6. 제대정맥혈장 내 아스코르빈산과 요산 농도는 각각 정상 임신군에서 561.4±53.1, 6419.5±452.2 nmol/mL, 자간전증군에서 401.8±47.8, 7789.2±551.7 nmol/mL로 자간전증군에서 아스코르빈산이 의의있게 낮았는데 (p<0.05) 반하여 요산은 의의있게 높았다 (p<0.05). 7. 제대동맥혈장내 아스코르빈산, 요산, 레티놀, 알파-토코페롤 및 감마-토코페롤 농도는 정상 임신군과 자간전증군에서 모두 유의한 차가 없었다. 결론 : 자간전증군의 자궁정맥혈장과 제대정맥혈장에서 지질과산화물 농도는 정상 임신군보다 높았고 항산화능은 낮았으며 특히 아스코르빈산이 낮았다. 이는 자간전증에서 산화촉진물과 항산화제의 불균형에 의한 산화적 스트레스가 자궁-태반축에서 발생함을 보여주는 소견이며, 이러한 산화적 스트레스가 자간전증 발생과 경과에 중요 인자로 관여하는 것으로 시사되었다. Objective : This study was aimed to investigate lipid peroxide levels, oxygen-radical absorbance capacity(ORAC), and antioxidant vitamin levels in uterine venous plasma, umbilical venous and arterial plasma and to evaluate their roles in the pathophysiology of preeclampsia and effects of oxidative stress on fetus. Methods : Samples of uterine venous plasma before and after delivery, umbilical venous and arterial plasma were collected from 18 normal and 16 preeclamptic women between 34 and 38 weeks gestation during Cesarean section. Lipid peroxide levels were measured thiobarbituric acid reaction. The ORAC values were measured by Cao's method. Ascorbic acid, retinol, α-tocopherol, and γ-tocopherol were measured by high performance liquid chromatography. Results : 1. Lipid peroxide levels in uterine venous plasma before and after delivery of women with preeclampsia were signficantly higher than that of women with normal pregnancy (5.56±0.57 vs. 3.48±0.29, p<0.01, 5.37±0.41 vs. 3.93±0.38 nmol/mg protein, p<0.01). 2. Lipid peroxide levels in umbilical venous and arterial plasma of women with preeclampsia were significantly higher than that of women with normal pregnancy (7.32±0.55 vs. 5.18±0.38, p<0.01, 8.21±0.81 vs 5.14±0.39 nmol/mg protein, p<0.01). Lipid peroxide levels in umbilical arterial plasma were significantly higher than that of umbilical venous plasma of women with preeclampsia (8.21±0.81 vs. 7.32±0.55 nmol/mg protein, p<0.05). 3. The ORAC values in uterine venous plasma before delivery of women with preeclampsia were significantly lower than that of women with normal pregnancy (10993.8±622.2 vs. 125961.1±726.1 U/mL, p<0.05). 4. The ORAC values in umbilical venous plasma of women with preeclampsia were significantly lower than that of women with normal pregnancy (10515.1±683.4 vs. 12804.6±463.7 U/mL, p<0.05). 5. Ascorbic acid levels in uterine venous plasma before and after delivery of women with preeclampsia were significantly lower than that of women with normal pregnancy (419.2±64.6 vs. 551.4±57.6 nmol/mL. p<0.05, 398.1±45.2 vs. 450.8±33.6 nmol/mL, p<0.05). 6. Ascorbic acid levels in umbilical venous plasma of women with preeclampsia were significantly lower than that of women with normal pregnancy (401.8±47.8 vs. 561.4±53.1 nmol/mL p<0.05). Uric acid levels in umbilical venous plasma of women with preeclampsia were significantly higher than that of women with normal pregnancy (7789.2±551.7 vs. 6419.5±452.2 nmol/mL p<0.05). Conclusion : The above results suggest that increased oxidative stress in uteroplacental unit is involved in the pathophysiology of preeclampsia and ascorbic acid may act as an important preventive factor in the development of preeclampsia.

        • SCOPUSKCI등재

          레이저 박피술의 피부면적 감소효과와 레이저 punch out 병변의 치유에 대한 실험적 연구

          강동희,윤을식,구상환,안덕선,박승하 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

          An experimental study was designed to analyze the surface reduction effect of ultrapulse carbon dioxide laser on the skin of guinea pigs receiving laser resurfacing. Two squares of skin measuring 3x3 ㎠ were designed on each side of the abdomen of guinea pigs(n=10). Five animals received laser resurfacing on their abdomen at energy of 250mJ/5 watt, and five other animals received 500 mJ/5 watt. On each animal, the left side square was treated with one pass of a CO2 laser, and the right side q=square was treated with two passes using a C.P.G. scanner. The size of the resurfacing area was determined by celluloid overlays at 1,2,3,4 and 6 weeks. Immediately following laser resurfacing, the area was decreased to 69%(left side) and 56%(right side) of the designed area in the 250 mJ/5 watt group, and 59% and 40% in the 500mJ/5 watt group. After 6 weeks, the resurfaced area had been reduced to 70% and 56% of the designed area in the 250mJ/5 watt group, and 60% and 40% in the 500mJ/5 watt group. As a result, the effect of surface reduction by CO2 laser resurfacing increased at a higher power and when more passes of the ultrapulse carbon dioxide laser were applied. The laser treated skin continued to maintain its contracted dimensions. These findings suggest that ultrapulse carbon dioxide laser may be an effective treatment method for rhytides. Another experiment was performed on multiple punch-out lesions on guinea pig skin(n=2) with 1,2,3 mm collimated hand pieces for the purpose of determining a new laser treatment method. After 4 weeks, on gross and histological examination, there were no differences in the healing of multiple punch-out lesions and the healing of punch-out lesions was complete without any scarring. These findings suggest that the laser punch-out method can be used for the treatment of acne scars.

        • KCI등재

          논문 : 몬순기후와 복잡지형의 특성을 갖는 광릉 산림유역의 물과 탄소순환에 대한 교차규모 연구로부터의 교훈

          이동호 ( Dong Ho Lee ),김준 ( Joon Kim ),김수진 ( Su Jin Kim ),문상기 ( Sang Ki Moon ),이재석 ( Jae Seok Lee ),임종환 ( Jong Hwan Lim ),손요환 ( Yo Whan Son ),강신규 ( Sin Kyu Kang ),김상현 ( Sang Hyun Kim ),김경하 ( Kyong Ha Kim 한국농림기상학회 2007 한국농림기상학회지 Vol.9 No.2

          광릉 슈퍼사이트에서 대기와 식생간의 에너지와 물질교환 규명은 지형과 식생의 복잡성으로 인해 많은 기술적인 어려움에 직면하고 있다. 따라서 KoFlux 연구에서는 상호보완적인 다중 분야의 연구를 통해 이러한 어려움을 극복하기 위한 시도를 해 오고 있다. 본 논문에서는 현재 진행중인 KoFlux 연구의 예비결과 중 특히 광릉사이트에서의 물/탄소수지, 물과 탄소순환의 상호관련성 그리고 몬순기후하의 생태계에서 탄소순환에 미치는 수문학적 요인의 중요성에 대해 중점적으로 논의하고자 한다. 광릉낙엽활엽수림의 순생태생산량 (NEP)은 광범위한 생태학적 연구결과에 따르면 약 ~2.6 t C/ha/y로 예상된다. 이를 미기상 플럭스 관측 결과와 함께 고려할 때 광릉 산림은 탄소의 중요한 육상흡원으로서 기능함을 예상할 수 있다. 다양한 생태수문 관측에 의해 규명된 유역단위 물수지에 의하면 연단위 전체강수량의 약 30-40%가 증발산 (ET)에 해당함을 나타내고 있다. 광릉산림의 대표적인 수종인 졸참과 서어나무의 잎에서 얻어진 탄소 안정동위 원소 조성에 근거하여 계산된 식물 성장기간의 평균 물 이용효율(WUE)은 약 ~12 μmol CO2/mmol H2O에 해당된다. 얻어진 증발산량과 물이용효율은 유역단위의 생태계 생산량을 산출하는데 이용될 수 있다. 나이테 성장량과 토양호흡량의 연단위 변화는 강수량과 강수의 패턴에 의해 크게 영향을 받음을 보이고, 이는 몬순기후에 영향을 받는 동아시아 지역 생태계에서 탄소 순환과정이 수문학적 조건과 밀접한 상관관계를 가짐을 지시한다. 연구지역의 공간적 특성을 정량화하기 위해 관측지의 구조 및 기능적 단위를 규명하기 위한 연구가 진행되고 있고 이를 통해 서로 다른 시공간 규모에서 진행되고 있는 연구의 결과물을 체계적으로 연결 통합하고 나아가 보다 광역적인 규모에서 대표적인 물/탄소 수지를 산출하기 위한 연구가 시도되고 있다. KoFlux Gwangneung Supersite comprises complex topography and diverse vegetation types (and structures), which necessitate complementary multi-disciplinary measurements to understand energy and matter exchange. Here, we report the results of this ongoing research with special focuses on carbon/water budgets in Gwangneung forest, implications of inter-dependency between water and carbon cycles, and the importance of hydrology in carbon cycling under monsoon climate. Comprehensive biometric and chamber measurements indicated the mean annual net ecosystem productivity (NEP) of this forest to be ~2.6 t C ha-1 y-1. In conjunction with the tower flux measurement, the preliminary carbon budget suggests the Gwangneung forest to be an important sink for atmospheric CO2. The catchment scale water budget indicated that 30~40% of annual precipitation was apportioned to evapotranspiration (ET). The growing season average of the water use efficiency (WUE), determined from leaf carbon isotope ratios of representative tree species, was about 12 μmol CO2/mmol H2O with noticeable seasonal variations. Such information on ET and WUE can be used to constrain the catchment scale carbon uptake. Inter-annual variations in tree ring growth and soil respiration rates correlated with the magnitude and the pattern of precipitation during the growing season, which requires further investigation of the effect of a monsoon climate on the catchment carbon cycle. Additionally, we examine whether structural and functional units exist in this catchment by characterizing the spatial heterogeneity of the study site, which will provide the linkage between different spatial and temporal scale measurements.

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