가성 장폐쇄로 발현한 부신경절종 1 예

김용태,이기업,박건춘,송영기,이문호,유은실,이준호,진태선 대한내과학회 1991 대한내과학회지 Vol.40 No.5

Phenochromocytoma is a catecholamine-secreting tumor, most of which grow at the adrenal gland. About 109p Of pheochromocytomas are detected at the extra-adrenal chromaffine tissues and are called paraganglioma. The main symptoms of pheochromacytoma include hypertension, headache, palpitation, and sweating. Gastrointestinal symptoms such as abdominal pain, constipation, and vomiting are found in 20∼40% of patients with pheochromocytoma, but these are usually overlooked because of the severe, prominant cardiovascular symptoms. Intestinal pseudo-obstruction without hypertension in pheochromocytoma is very rarely found. It is caused by the decreased motility of the intestine and the over-contraction of the intestinal sphincter, which are caused by the unbalanced activation of α-and β-adrenal receptors. It can be hypothesized that catecholamine receptors in the cardiovascular system are down-regulated or desensitized, but those in the intestine remain intact. We report herein a case of pheochromocytoma in which intestinal pseudo-obstruction was the main presenting clinical manifestation. Symptoms of intestinal pseudo-obstruction were completely relieved by administration of phenoxybenzamine, an α-receptor blocker, and excisional surgery.

한국에서의 Human T-Cell Leukemia Virus Type-1(HTLV-1)에 대한 혈청학적 및 역학에 관한 연구

이영열,이성열,김은실,이홍복,김병국,이문호,박선양,김노경,서철원,규경채,최강원,조한익,고월청,야마구찌이찌세이 대한내과학회 1986 대한내과학회지 Vol.31 No.2

Type-C retrovirus, human T-cell leukemia virus type-l(HTLV-1), has been shown to be associated etiologically with adult T-cell leukemia, which is an endemic disease in southwestern parts of Japan. We examined the seroepidemiological characteristics of antibody to adult T-cell leukemia virus associated antigen (anti-ATLA-antibody) by the indirect immunofluorescent assay and ELISA from the healthy individuals and various diseased patients in the Republic of Korea, a country adjacent to Japan in which HTLV-1 is endemic. The results were as follows. 24 out of 9,603 individuals(0.25%) were seropiositive. The positve rate was 0.17% in males and 0.36% in females, the sex difference was female predominent relatively. HTLV-1 carriers were found 16 individuals in Seoul, 5 in Kyonggi area, 1 in Chungnam and Jonbuk, respectively, but found only 1 individual in Busan city and Jaejoo area close to southwestern parts of Japan. Positive rate to anti-ATLA-antibody seemed to be high in older age, especially at the 50s(0. 4Yo). In conclusion the prevalence rate of anti-ATLA- antibody seemed to be very low in the Republic of Korea adjacent to Japan in which HTLV-1 is endemic and no patient with adult T-cell leukemia has been found as yet. Also we noted that the Republic of Korea is not an endemic area to HTLV-1.

다이프로피온산 베클로메타손과 부데소니드의 투여 용량에 따른 코르티솔 농도와 변화

이영승,김종구,이양근,최수미,송하숙,이용철 대한내과학회 1993 대한내과학회지 Vol.45 No.6

Background: Topical inhaled steroids, budesonide (Bu) and beclomethasone dipropionate (BDP) is now established in the management of chronic: asthma. These have high topical anti-inflammatory activity but low systemic activity. This study was performed to determine the effects of two inhaled corticosteroids, Bu and BDP, on the adrenocortical supression in thirty patients, eighteen chronic obstructive pumonary diseases and twelve bronchial asthma (aged 33-76 years). Methods: The adrenocortical function was assessed by measurement of plasma cortisol concentration at 8 o' clock in morning and free cortisol in 24-hour urine collection at interval, No steroid was taken during the pretreatment period of 10 days, thereafter each subject inhaled Bu or BDP aerosol, in daily doses of 800 or 1,600 micrograms for 12 days. The dose was delieved by metered dose inhaler (MDI) or diskhaler. No steroid was taken during the final 6 days of the study. Results: The plasma cortisol and 24-hour urinary free cortisol were decreased during the treatment period in patients inhaled Bu in daily doses of 800 and 1,600 micrograms. In contrast, plasma cortisol was decreased on the 12th day of treatment period in patients inhaled RDP, in daily doses of 800 micrograms (P less than 0.05). The plasma cortisol and 24-hour urinary free cortisol were decreased (P less than 0.05) on the 9 and 12 th day of treatment period in patients inhaled BDP in daily doses of 1,600 micrograms. Conclusion: These results suggested that suppression of the endogenous cortisol secretion occurs at inhaled budesonide and beclomethasone dipropionate is less suppressed on the adrenocortical function than budesonide in dose dependent fashion during the early periods,

고 규소강에서 규칙상 소멸조건에 관한 연구

이택동,유지형,신제식,배준수,이진형,이혁모 대한금속재료학회(대한금속학회) 2001 대한금속·재료학회지 Vol.39 No.4

The ordered phase was tried to disappear in 6.5% Si steel to reduce the power loss and enhance the economic interests. They were prepared by the conventional casting or spray forming method, and they were investigated using the transmission electron microscopy(TEM). The variation in the methods of preparing the specimen did not result in any difference in suppressing the ordered B2 phase in the Fe-Si binary system. It was almost impossible to suppress this ordered phase keeping the silicon level as high as 6.5% even after the heat treatment at 1000℃ for 24 hr or after hot rolling. It was necessary to change the silicon level and control the cooling rate to prevent the ordering reaction, especially, in cooling after heat treatments. The silicon level of 5.8% was obtained as a maximum desirable value.

지하철의 사상사고 및 운전장애 분석에 관한 연구

이동훈,목연수,장성록,권혁무,윤원영,옥영석,최용석,배동철 한국산업안전학회 1999 한국안전학회지 Vol.14 No.3

The purpose of this study is to analyze death injuries and operation troubles of urban transit. No difference was shown in death rates between Line 1 of Pusan urban transit and Line 5, 7, and 8 of Seoul metropolitan transit. And relief time by another train did not depend upon the number of crews. We concluded that thorough inspection and preventive maintenance of trains and facilities are necessary for safe and timely service of urban transit.

당뇨병의 병형에 따른 합병증에 관한 연구(예보)

이현철,허갑범,이이형,윤정환,임승길,윤금석,김원중,김현만 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.2

당뇨성망막증에서의 방사성핵종 망막신티그라피의 이용에 관한 연구

이상우,박영태,이형호,최승환,안일민,서순규,진용한,이태수 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.1

Chemical Bath Deposition 방법으로 제작한 CdSe 박마의 특성

신영진,홍광준,이상열,유상하,서상석,문종대,신현길,김택성,송정훈,유기수,정태수 한국센서학회 1993 센서학회지 Vol.2 No.1

Polycrystalline CdSe thin films were grown on ceramic substrate using a chemical bath deposition (CBD) method. They were annealed at various temperature and X-ray diffraction patterns were measured by X-ray diffractometer in order to study CdSe polycrystal structure. Using extrapolation method of X-ray diffraction patterns for the CdSe samples annealed in N₂ gas at 450℃ it was found hexagonal structure whose lattice parameters a_o and c_o were 4.302 A and 7.014 A, respectively. Its grain size was about 0.3 ㎛. Hall effect on this sample was measured by Van der Pauw method and studied on carrier density and mobility depending on temperature. From Hall data, the mobility was likely to be decreased by piezo electric scattering at temperature range of 33 K and 200 K, and by polar optical scattering at temperature range of 200 K and 293 K. We measured also spectral response, sensitivity (γ), maximum allowable power dissipation and response time on these samples.

방전 플라스마에 의한 CFC-12(CCl2F2)의 분해

황명환,우인성,조정국,강현춘,안형환,이한섭,강안수 한국산업안전학회 1999 한국안전학회지 Vol.14 No.3

Decomposition efficiency, power consumption, and applied voltage of CFC(Chlorofluorocarbon) were investigated by SPCY(surface induced discharge plasma chemical processing) reactor to obtain optimum process variables and maximum decomposition efficiencies. Decomposition efficiency of CFC-12 with various electric frequencies(5∼50㎑). flow rates (100∼1,000mL/min), initial concentrations(100∼1,000ppm), electrode materials(W, Cu. Al), electrode thickness(1, 2, 3mm) and reference gases(N₂, O₂, air) were measured and the products were analyzed with FT-IR. Experimental results showed that at the frequency of 10kHz, the highest decomposition efficiency of 92.7% for CFC-12 were observed at the power consumptions of 29.6W, respectively, and that decomposition efficiency decreased with increasing frequency above 20㎑ and decomposition efficiency per unit power were 3.13%/W for CFC-12. Decomposition efficiency was increased with increasing residence times and with decreasing initial concentration of pollutants. Decomposition efficiency was increased with increasing thickness of discharge electrode and the highest decomposition efficiency was obtained for the electrode diameter of 3mm. As the electrode material, decomposition efficiency was in order that tungsten(W), copper(Cu), aluminum (Al).

가토에서 CCNU 로 유발된 골수 저형성증의 혈액학적 소견과 골수스캔의 변화에 관한 연구

김승택,이명철,최두혁,고창순,김병국,이문호,박선양,최성재,김노경,최영희 대한내과학회 1986 대한내과학회지 Vol.30 No.1

To understand systematically the hematological changes including the bone marrow changes in chemotherapeutic agent-induced bone marrow hypoplasia and to define the relationship between hematological and bone marrow scan findings and prognosis of the hypoplasia, CCNU (lomustine) was given orally to 44 rabbits to induce hypoplasia of the bone marrow. And serial changes of peripheral blood and bone marrow findings and (111)In Cl(3)((111)In scan)/(99m)Tc tin colloid bone marrow scan((99m)Tc scan) were checked before and after induction of hypoplasia. With assessment of 28 evaluable rabbits, the following results were obtained: 1) Significant hypoplasia of the bone marrow developed around day 4 of CCNU administration and recovered around day 14(cellularity 51,4±13.5% and 24. 5±14.97o before and after CCNU respectively, p<005). Megakaryocyte count was significantly depressed from 95.67,26% to 36.7$gt;31.82%(P$lt;0.005). M: E ratio was decreased from 162±1.19 to 0, 0.5$lt;0. 43(p±0.005). Shift to left(475), maturation a(40%), naked nucleus and degenerated cells(20%), increase of lymphocytes(47%), monocytes and reticulum cells were also found. 2) The uptake ratio of the 99(m)Tc tin colloid bone marrow scan was markedly increased in contrast to the depression of the bone marrow(4.4±2.12 and 14.1±7.06 before and 4 days after CCNU, respectively, p40. 005). Tc scan uptake ratio was inversely related to the cellularity(r=-0.442, p$lt;0.05) and megakaryocyte number of the bone marrow(r= 0.89, p< 0.01) and peripheral blood granulocyte (r = 0. 54. Pg0.01) and platelet count(r=0.40, p$lt;0.05). There was not significant correlation between (111)In scan uptake ratio and hematologic parameters. 3) The amplitude of the change of the (99m)Tc scan uptake ratio was significantly related to the prognosis of the rabbits with experimentally induced hypoplasia of the bone marrow(dead 5.1±2,67, survivors 2,5±0.96, P<0.01). The change of the (111)In scan uptake ratio was not related to the prognosis of these rabbits. In experimentally induced rrow hypoplasia, morphologic changes in addition to the numerical changes of the bone marrow elements were observed. And serial (99)Tc scan of the bone marrow appears to be helpful assessing the severity and predicting the outcome of bone marrow hypoplasia.