An Overview of Deep Learning Algorithms and Their Applications in Neuropsychiatry

Gokhan Guney,Busra Ozgode Yigin,Necdet Guven,Yasemin Hosgoren Alici,Burcin Colak,Gamze Erzin,Gorkem Saygili 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.2

Deep learning (DL) algorithms have achieved important successes in data analysis tasks, thanks to their capability of revealing complex patterns in data. With the advance of new sensors, data storage, and processing hardware, DL algo-rithms start dominating various fields including neuropsychiatry. There are many types of DL algorithms for different data types from survey data to functional magnetic resonance imaging scans. Because of limitations in diagnosing, esti-mating prognosis and treatment response of neuropsychiatric disorders; DL algorithms are becoming promising approaches. In this review, we aim to summarize the most common DL algorithms and their applications in neuro-psychiatry and also provide an overview to guide the researchers in choosing the proper DL architecture for their research.

INITIAL COEFFICIENT BOUNDS FOR SUBCLASSES OF BI-UNIVALENT FUNCTIONS ASSOCIATED WITH THE CHEBYSHEV POLYNOMIALS

HATUN OZLEM GUNEY,G. MURUGUSUNDARAMOORTHY,K. VIJAYA 장전수학회 2018 Advanced Studies in Contemporary Mathematics Vol.28 No.3

In this paper, we introduce and investigate new subclasses of bi-univalent functions defined in the open unit disk, involving special functions associated with Chebyshev Polynomials. Furthermore, we find estimates of first two coeffcients of functions in these classes, making use of the Chebyshev polynomials. Also, we give Fekete-Szego inequalities for these function classes. Several consequences of the results are also pointed out.

Use of UVP to Investigate the Evolution of Bed Configuration

M. Sukru Guney,Gokcen Bombar,Aysegul O. Aksoy,Mustafa Dogan 대한토목학회 2013 KSCE JOURNAL OF CIVIL ENGINEERING Vol.17 No.5

Ultrasonic Velocity Profiler (UVP) is a widely used instrument which allows the determination of the complete velocity profile. UVP can also measure the echo amplitude in the mean time. In this study, it is intended to use the UVP transducers in an indirect way to detect the bottom surface by orienting them vertically downward. Preliminary experiments were conducted with immobile bed by using uniform, non-uniform sediment as well as wooden and plastic surface. It was appeared that the first remarkable peak corresponds to the bottom surface. The time variations of local bed elevations were registered by applying this technique in order to determine the erosion and deposition around a bridge pier and local scour around a horizontal submerged pipe. It was revealed that the so registered scour depths were in good agreement with those observed during the experiments. Consequently, it is demonstrated that time varied bed elevations can be measured via the first peak value of echo amplitudes by placing UVP transducers vertically.

Performance of the Immunoglobulin G Avidity and Enzyme Immunoassay IgG/IgM Screening Tests for Differentiation of the Clinical Spectrum of Toxoplasmosis

Tanyuksel, Mehmet,Guney, Cakir,Araz, Engin,Saracli, M.Ali,Doganci, Levent The Microbiological Society of Korea 2004 The journal of microbiology Vol.42 No.3

Toxoplasmosis has been well known as an important human infection to consider especially in pregnant women. Although many serologic methods are available, the diagnosis of toxoplasmosis can be extremely difficult. The presence of increased levels of Toxoplasma-specific IgG antibodies indicates an infection, but it does not differentiate between a recent and past infection. The purpose of our study was to compare the performance of the ELISA T. gondii IgG/IgM test, a widely used enzyme-linked immunosorbent assay, to the ELISA IgG avidity method. One hundred and four serum samples (from 38 males and 66 females) were tested and evaluated from symptomatic patients (chorioretinitis, lymphadenopathy), and from women in their first trimester of pregnancy who were suspected of having toxoplasmosis, The high IgG avidity and ELISA IgG antibody levels were in agreement for 51 of the specimens (49.0%). Thirty-eight discrepant (borderline) results from the IgG avidity method were positive for IgM (3 specimens) and IgG (37 specimens). Interestingly, out of the eight serum samples that were positive for both IgG and IgM antibodies, two samples were low IgG avidity, and three samples were borderline. There was no statistically significant relation observed between the results of the IgG avidity method and the ELISA IgG test, and the IgG avidity method and ELISA IgM test (X$^2$=1.987; p=0.370 and X$^2$=2.152; p=0.341, respectively). The IgG avidity method was considered easy to perform and an acceptable approach for the differentiation of discrepant results (recent/chronic) and for the current detection of T. gondii antibodies. We concluded that the determination of IgG avidity is a helpful tool for the diagnosis of the ocular form of toxoplasmosis and it is a safe method for screening this disease in the first trimester of pregnancy.

Analysis of Consolidation Settlement of Normally Consolidated Soil by Layering under 3D Conditions

윤찬영,C. Guney Olgun 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.6

This study analyzed the effects of conventional practice of calculating consolidation settlement of soft ground by dividing the ground into one or more layers. Based on a numerical analysis of the accuracy of the calculation and the settlement behavior resulting from layering, this study found that the existing settlement calculation method always underestimates settlement, and that the smaller the number of dividing layers, the smaller the calculated settlement is observed. In addition, when the ground is divided into an infinite number of layers, the settlement is 1.2 to 50 times larger than the case when the ground is considered as a single layer, and the difference grows larger at the lower ratio of an applied pressure to an effective stress (A0), the higher ratio of a layer thickness to a footing width (H/B), and the lower ratio of the length to width of a footing (L/B). The exact settlement can also be obtained under a single-layer condition, even when using the existing settlement calculation method, if the representative depth of calculation of the effective stress is set at a depth of approximately 10-38% from the top of the clay layer.

Medicinal leech therapy—an overall perspective

Ali K. Sig,Mustafa Guney,Aylin Uskudar Guclu,Erkan Ozmen 한국한의학연구원 2017 Integrative Medicine Research Vol.6 No.4

Complementary medicine methods have a long history, but modern medicine has just recently focused on their possible modes of action. Medicinal leech therapy (MLT) or hirudotherapy, an old technique, has been studied by many researchers for possible effects on various diseases such as inflammatory diseases, osteoarthritis, and after different surgeries. Hirudo medicinalis has widest therapeutic usage among the leeches, but worldwide, many different species were tested and studied. Leeches secrete more than 20 identified bioactive substances such as antistasin, eglins, guamerin, hirudin, saratin, bdellins, complement, and carboxypeptidase inhibitors. They have analgesic, anti-inflammatory, platelet inhibitory, anticoagulant, and thrombin regulatory functions, as well as extracellular matrix degradative and antimicrobial effects, but with further studies, the spectrum of effects may widen. The technique is cheap, effective, easy to apply, and its modes of action have been elucidated for certain diseases. In conclusion, for treatment of some diseases, MLT is not an alternative, but is a complementary and/or integrative choice. MLT is a part of multidisciplinary treatments, and secretes various bioactive substances. These substances vary among species and different species should be evaluated for both treatment capability and their particular secreted molecules. There is huge potential for novel substances and these could be future therapeutics.

Performance of the Immunoglobulin G Avidity and Enzyme Immunoassay IgG/IgM Screening Tests for Differentiation of the Clinical Spectrum of Toxoplasmosis

Mehmet Tanyuksel,Cakir Guney,Engin Araz,M.Ali Saracli,Levent Doganci 한국미생물학회 2004 The journal of microbiology Vol.42 No.3

Toxoplasmosis has been well known as an important human infection to consider especially in pregnant women. Although many serologic methods are available, the diagnosis of toxoplasmosis can be extremely difficult. The presence of increased levels of Toxoplasma-specific IgG antibodies indicates an infection, but it does not differentiate between a recent and past infection. The purpose of our study was to compare the performance of the ELISA T. gondii IgG/IgM test, a widely used enzyme-linked immunosorbent assay, to the ELISA IgG avidity method. One hundred and four serum samples (from 38 males and 66 females) were tested and evaluated from symptomatic patients (chorioretinitis, lymphadenopathy), and from women in their first trimester of pregnancy who were suspected of having toxoplasmosis. The high IgG avidity and ELISA IgG antibody levels were in agreement for 51 of the specimens (49.0%). Thirty-eight discrepant (borderline) results from the IgG avidity method were positive for IgM (3 specimens) and IgG (37 specimens). Interestingly, out of the eight serum samples that were positive for both IgG and IgM antibodies, two samples were low IgG avidity, and three samples were borderline. There was no statistically significant relation observed between the results of the IgG avidity method and the ELISA IgG test, and the IgG avidity method and ELISA IgM test (χ2=1.987; p=0.370 and χ2=2.152; p=0.341, respectively). The IgG avidity method was considered easy to perform and an acceptable approach for the differentiation of discrepant results (recent/chronic) and for the current detection of T. gondii antibodies. We concluded that the determination of IgG avidity is a helpful tool for the diagnosis of the ocular form of toxoplasmosis and it is a safe method for screening this disease in the first trimester of pregnancy.

SUBORDINATION RESULTS FOR CERTAIN SUBCLASSES BY USING INTEGRAL OPERATOR DEFINED IN THE SPACE OF ANALYTIC FUNCTIONS

Sakar, F. Muge,Guney, H. Ozlem The Honam Mathematical Society 2018 호남수학학술지 Vol.40 No.2

In this study, firstly we introduce generalized differential and integral operator, also using integral operator two classes are presented. Furthermore, some subordination results involving the Hadamard product (Convolution) for these subclasses of analytic function are proved. A number of consequences of some of these subordination results are also discussed.

Artificial NARX Neural Network Model of Wind Speed: Case of Istanbul-Avcilar

Calik Huseyin,Ak Namik,Guney Ibrahim 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.5

Wind farms have a focus role in environmentally friendly energy production. There are short-term estimates of wind speed in planning energy production in wind power plants. In this article, we analyzed the wind speed in the Istanbul Avcılar region by an artifi cial neural network method (ANN) and regression method. One of the methods commonly used in estimation processes is Nonlinear Autoregressive Exogenous (NARX). We divide the data into three parts 70%, 15%, and 15%, respectively, for learning, validation, and testing. We used the Levenberg–Marquardt (LM) algorithm for data network training. We compared the predicted wind speed with the measured and tested values. We used MATLAB software in the analysis of the model. We obtained system outputs and regression models of wind speed with artifi cial neural network simulations. Besides, we calculated the eff ect sizes.

Familial gigantiform cementoma with Ehlers - Danlos syndrome: A report of 2 cases

Nihan Aksakallı,Ceren Guney Tolgay,Fatma unalan,Zeynep Mumcu,Gamze Aren,Olcay sakar 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.2

Ehlers-Danlos syndrome is an autosomal dominant hereditary disorder of connective tissue, while familial gigantiform cementoma is a condition that usually manifests as multiple radiopaque cementum-like masses throughout the jaws. This case report discusses the oral management and prosthetic rehabilitation of two patients presenting familial gigantiform cementoma with Ehlers-Danlos Syndrome.