obIncreased Laterality of the Thalamus in Children and Adolescents with Asperger’s Disorder: An MRI and Proton Spectroscopy Study

Gokce Nur Say,Buyamin Sahin,Kerim Aslan,Seher Akbas,Lutfil Incesu,Meltem Ceyhan 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.3

Objective-Thalamic abnormalities have been reported in people with pervasive developmental disorders (PDD) including Asperger’s Disorder (ASP). The aim of the present study was to compare the volume and volume fraction of the thalamus and the metabolite concentrations in children and adolescents with ASP using the magnetic resonance imaging and proton magnetic resonance spectroscopy. Additionally, the relationships between thalamic abnormalities and clinical features were examined. Methods-Volume and volume fractional and metabolic measurements of bilateral thalamus were collected from 15 boys with ASP with a total IQ over 70 (age range 7–18 years, mean age 11.6±3.79 years), and 15 healthy controls matching age, sex and IQ. The thalamic volumes, hemisphere volumes and total brain volumes (TBV) were estimated using the stereological methods on magnetic resonance images. Chemical metabolites of thalamus were evaluated by 1H spectroscopy. Results-No differences in thalamic volumes, volume fractions and metabolites were observed between the groups. There were significant correlation between thalamic volume and total brain volume in both groups. The ASP group showed a significant left-minus-right thalamus difference as well as a significantly greater laterality index. In addition, a significant correlation between the laterality index and Autism Behavior Checklist language scores was observed. Conclusion-Findings from this investigation point to a significant increase in laterality of the thalamus and a relationship with language problems in individuals with ASP. Our findings suggest that thalamic abnormalities may be related to mild language problems observed in ASP.

The Concept of Emotion and Catharsis in the Cinema Audience in the Context of the Psychoanalytic Approach

Gokce Buluk,윤학로 강원대학교 인문과학연구소 2022 Journal of Humanities Therapy Vol.13 No.2

In this article, the nature of the psychoanalytic film theory in perceiving the film construction and the nature of the audience's emotion transfer will be discussed through the philosophy theory of "catharsis". It is aimed to analyze the cinema in itself, to benefit from the psychoanalyst approach to the relationship between the word, image, symbol, and object of the emotional discharge in the audience. The universality of cinema carries a common language as the journey of “knowing people, and making sense of people”. Despite the different languages, cultures, and fantastic elements, cinema succeeds in reaching common feelings in the audience. People watch movies to live a fantasy. The reflection of the fictionalized fantasies enables them to re-live the adventure they made in their inner world. The movie theater or the place where the movie is watched portrays the inner world of the individual. The film, which reflects one's image, will allow individuals to meet with the inner world again. The purpose of this article is to construct a new world of meaning by experiencing the phenomena such as examining and reviewing their inner world, collective unconscious, symbol, and imagination in emotional discharge. As a result, reactions that emerge in action are now replaced by a new version of emotions. Identification took the new form of emotion into internal memory and left its place to dreams, imaginations, and desires. In this paper, the bond that the person establishes with the work of art is examined through the psychoanalytic theories of Sigmund Freud, Carl Gustav Jung, and Jacques Lacan and emphasized the concept of catharsis as an individual's spiritual need beyond its philosophical dimension. The article consists of three parts. The psychoanalytic approach, the theory of catharsis, and the importance of these two theories in cinema on the audience are discussed. The first part focuses on the basic concepts of Freud, Lacan, and Jung's psychoanalytic theory. To determine the hidden causes of the action, the conditions under which the psychoanalytic approach was put forward and its connection with the films were examined and the second part, the connection of the expression of emotional discharge with the inner world of the individual in the theory of catharsis is examined, and the place of catharsis in the psychoanalytic approach is discussed beyond being just a concept of art philosophy. Lastly, in the third part, the effect of movies on emotions is evaluated.

APPLICATION OF IMPULSIVE DETERMINISTIC SIMULATION OF BIOCHEMICAL NETWORKS VIA SIMULATION TOOLS

GOKCE TUNCER,VILDA PURUTCUOGLU 장전수학회 2017 Proceedings of the Jangjeon mathematical society Vol.20 No.1

In order to understand the possible behaviour of biochemi- cal networks, deterministic and stochastic simulation methods have been developed. However in some cases, these methods should be broaden. For example, if the biochemical system is subjected to the unexpected effects causing abrupt changes in the network, the ordinary simulation algorithms cannot capture these impulsive expressions. In this study, we select the simulations tools, specifically, COPASI and Systems Biology Toolbox for MATLAB among alternatives that en- able us to represent the impulsive changes in the system via impulsive or adaptive deterministic simulation algorithms. Accordingly, we com- pare these tools by applying the two major impulsive scenarios, namely, impulses for fixed times and fixed states, based on their accuracies and computational demands. We evaluate our results for small and large systems, respectively.

Back-reflection Second-harmonic Generation of (111)Si: Theory and Experiment

Gokce, B.,Gundogdu, K.,Adls, E. J.,Aspnes, D. E. Korean Physical Society 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.5

Relationship between Class III malocclusion and hyoid bone displacement during swallowing: a cine-magnetic resonance imaging study

Gokce, Sila Mermut,Gokce, Hasan Suat,Gorgulu, Serkan,Karacay, Seniz,Akca, Eralp,Olmez, Huseyin The Korean Association Of Orthodontists 2012 대한치과교정학회지 Vol.42 No.4

Objective: The displacement of the hyoid bone (HB) is a critical biomechanical component of the swallowing function. The aim of this study was to evaluate the swallowing-induced vertical and horizontal displacements of the HB in subjects with 2 different magnitudes of skeletal Class III malocclusion, by means of real-time, balanced turbo-field-echo (B-TFE) cine-magnetic resonance imaging. Methods: The study population comprised 19 patients with mild skeletal Class III malocclusion, 16 with severe skeletal Class III malocclusion, and 20 with a skeletal Class I relationship. Before the commencement of the study, all subjects underwent cephalometric analysis to identify the nature of skeletal malformations. B-TFE images were obtained for the 4 consecutive stages of deglutition as each patient swallowed 10 mL of water, and the vertical and horizontal displacements of the HB were measured at each stage. Results: At all stages of swallowing, the vertical position of the HB in the severe Class III malocclusion group was significantly lower than those in the mild Class III and Class I malocclusion groups. Similarly, the horizontal displacement of the HB was found to be significantly associated with the severity of malocclusion, i.e., the degree of Class III malocclusion, while the amount of anterior displacement of the HB decreased with an increase in the severity of the Class III deformity. Conclusions: Our findings indicate the existence of a relationship between the magnitude of Class III malocclusion and HB displacement during swallowing.

Serotonin Expression in Lichen Planus Lesions and Its Relationship with Depression/Anxiety

( Gokce Isil Kurmus ),( Muzeyyen Gonul ),( Filiz Canpolat ),( Demet Yilmazer ),( Eylem Sahin Cankurtaran ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.2

Background: Psychological factors such as stress, depression, and anxiety have been documented to contribute to the development of lesions in lichen planus (LP). Objective: To evaluate the relationship between serotonin expression in LP lesions and depression/anxiety. Methods: Forty patients (22 females, 18 males) with LP and 20 healthy control subjects were included in this study. The severity of LP was assessed with the palmar method (using the measurement of affected body surface area [BSA]). The depression and anxiety scores were measured with Beck's depression inventory (BDI) and Beck's anxiety inventory (BAI). The expression of serotonin was determined via immunohistochemistry in LP lesions and in the control group skin using a monoclonal antibody to serotonin. Results: The skin biopsies of the LP patients had significantly higher levels of serotonin than those of the control subjects (p<0.001). In the LP patients, and there was a positive correlation between serotonin expression and LP severity (p=0.022). Based on the results from the BDI and BAI, there was a significant relationship between the severity of depression/anxiety and intensity of serotonin expression (p <0.001). Conclusion: Data from this study suggest that serotonin may have a possible role in the pathogenesis of LP. Further, the relationship between serotonin expression in acute cutaneous lesions and the depression/anxiety scores indicates that serotonin may be a mediator for the association of LP and depression/anxiety simultaneously. There is a need for more specific studies showing the expression of serotonin in the lichen planus to demonstrate the cause or effect. (Ann Dermatol 31(2) 146∼153, 2019)

Control of the Oxidation Kinetics of H-terminated (111)Si by Using the Carrier Concentration and the Strain: a Second-harmonic-generation Investigation

B. Gokce,K. Gundogdu,데이비드에스프네스 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.10

We discuss recent results regarding the effects of strain, carrier type and concentration on the oxidation of H-terminated (111)Si. Second-harmonic-generation data show that this is a two-stage process where the H of the “up” bonds of the outermost Si layer is replaced by OH, followed by O insertion into the “back” bonds. These data provide additional detailed information about both stages. In particular, directional control of the in-plane surface chemistry by using the applied uniaxial stress provides new opportunities for interface control.

Perspectives of Women during Reproductive Years for Cervical Cancer Scans and Influencing Factors

Acar, Gokce Banu,Pinar, Gul Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16

Background: This descriptive study was performed in order to assess health perspectives of women, who applied to Yildirim Beyazit University Ataturk Education and Research Hospital, Outpatient Clinic of Obstetrics and Gynecology for cervical cancer scans and were in the reproductive years. Factors influencing their perspectives were also assessed. Materials and Methods: In this study, a simple random sampling formula was adopted to calculate the volume (300) of the targeted sample. Results of the research were obtained through individual diagnosis form and cervical cancer and the Pap smear test health belief model scale (HBMS). Results: It was found that 75.0% of the women heard of the Pap smear test before, and 48.7% had undertaken one. Some 51.4% of the women who had Pap smear test expressed that they had the test at irregular periods. Most of the women stated that they heard about the smear test from the health staff (51.7%). Lack of any health complaints (28.3%) and not having adequate information about the test (21.0%) were among the reasons for not undergoing a Pap smear test. It was found that lower dimension average scores of the women obtained from the cervical cancer and Pap smear test HBMS varied from $7.7{\pm}2.3$ to $33.5{\pm}9.3$. When the lower dimension average scores of women from the HBMS were examined, the perception of usefulness was high but the susceptibility and health motivations were low. Conclusions: In this study, it was determined that the awareness of women about cervical cancer and the Pap smear test was insufficient, and susceptibility and motivation perception towards having a Pap smear test were low.

Back-reflection Second-harmonic Generation of (111)Si: Theory and Experiment

B. Gokce,K. Gundogdu,E. J. Adles,데이비드에스프네스 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.51

We consider second-harmonic generation (SHG) from a (111) surface of a tetrahedrally bonded semiconductor illuminated at normal incidence by a focused pump beam of Gaussian cross section as a model of SHG by focused beams. Calculations are done in the anisotropic bond model (ABM) and the results are applied to Si. The unit-cell configuration is simple enough for the calculations to be done analytically, so the results can be compared directly to similar calculations done for amorphous material. Although the differences in unit-cell symmetry occur on the atomic scale, they lead to large differences in the spatial distribution of the emerging radiation. Lateral focusing, which might be expected to increase the bulk contribution to SHG by increasing the lateral field gradient, has little effect; the spatial-dispersion contribution remains dominated by the phase term. Focusing does not inhibit backscattered SHG from the bulk, although our data on the oxidation of H-terminated (111)Si clearly show that in some cases the interface contribution dominates by a wide margin.

A CLASS OF MÖBIUS ITERATED FUNCTION SYSTEMS

Cakmak, Gokce,Deniz, Ali,Kocak, Sahin Korean Mathematical Society 2020 대한수학회논문집 Vol.35 No.3

We characterize Möbius functions mapping the unit disc of the complex plane contractively into itself. We then give a procedure to produce Möbius iterated function systems on the unit disc.