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        A Rare Case of Ectopic Thyroid: Case Report and Literature Review

        Ghattas Souad,Maalouf Hani,Hadeer Ribal Aby,Bitar Jad Al,Youniss Ahmad,Chakif Aya El,Khoury Mansour El 대한내분비외과학회 2024 The Koreran journal of Endocrine Surgery Vol.24 No.1

        An ectopic thyroid is a very rare entity defined as a thyroid not located in the anterior neck region between the 2nd and 5th tracheal rings. An ectopic thyroid can be found anywhere along the line of the obliterated thyroglossal duct, from the base of the tongue to the mediastinum. Herein, we report the case of a 34-year-old female patient with a follicular neoplasm of a thyroid nodule who presented for thyroidectomy. The patient was found to have an aberrant thyroid, localized postoperatively to be lingual. A careful ultrasound evaluation of all neck regions performed preoperatively by surgeons is important to avoid misdiagnosis. Controversies exist about the optimal treatment of ectopic thyroid. Most authors agree that the treatment depends on the patient’s age, location of the ectopic thyroid, size, and the presence of symptoms or complications such as malignancy.

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        Clinical and Prognostic Features of Erionite-Induced Malignant Mesothelioma

        Ersin Demirer,Elamin M. Elamin,Christian F. Ghattas,Mohamed O. Radwan 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.2

        This review analytically examines the published data for erionite-related malignantpleural mesothelioma (E-MPM) and any data to support a genetically predisposedmechanism to erionite fiber carcinogenesis. Adult patients of age ≥18 years with erionite-related pleural diseases and genetically predisposed mechanisms to erionite carcinogenesis were included, while exclusion criteria included asbestos- or tremolite-related pleural diseases. The search was limited to human studies though not limited to a specific timeframe. A total of 33 studies (31042 patients) including 22 retrospective studies, 6 prospective studies, and 5 case reports were reviewed. E-MPM developed in some subjects with high exposures to erionite, though not all. Chest CT was more reliable in detecting various pleural changes in E-MPM than chest X-ray, and pleural effusion was the most common finding in E-MPM cases, by both tests. Bronchoalveolar lavage remains a reliable and relatively less invasivetechnique. Chemotherapy with cisplatin and mitomycin can be administered either alone or following surgery. Erionite has been the culprit of numerous malignantmesothelioma cases in Europe and even in North America. Erionite has a higher degree of carcinogenicity with possible genetic transmission of erionite susceptibilityin an autosomal dominant fashion. Therapeutic management for E-MPM remains very limited, and cure of the disease is extremely rare.

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