Marine sponge-associated bacteria as a potential source for polyhydroxyalkanoates

Sathiyanarayanan, Ganesan,Saibaba, Ganesan,Kiran, George Seghal,Yang, Yung-Hun,Selvin, Joseph Informa UK (Taylor Francis) 2017 Critical reviews in microbiology Vol.43 No.3

Vibration and stability of fluid conveying pipes with stochastic parameters

Ganesan, R.,Ramu, S. Anantha Techno-Press 1995 Structural Engineering and Mechanics, An Int'l Jou Vol.3 No.4

Flexible cantilever pipes conveying fluids with high velocity are analysed for their dynamic response and stability behaviour. The Young's modulus and mass per unit length of the pipe material have a stochastic distribution. The stochastic fields, that model the fluctuations of Young's modulus and mass density are characterized through their respective means, variances and autocorrelation functions or their equivalent power spectral density functions. The stochastic non self-adjoint partial differential equation is solved for the moments of characteristic values, by treating the point fluctuations to be stochastic perturbations. The second-order statistics of vibration frequencies and mode shapes are obtained. The critical flow velocity is first evaluated using the averaged eigenvalue equation. Through the eigenvalue equation, the statistics of vibration frequencies are transformed to yield critical flow velocity statistics. Expressions for the bounds of eigenvalues are obtained, which in turn yield the corresponding bounds for critical flow velocities.

SFRHPC interior beam-column-slab joints under reverse cyclic loading

Ganesan, N.,Nidhi, M.,Indira, P.V. Techno-Press 2015 Advances in concrete construction Vol.3 No.3

Beam-column joints are highly vulnerable locations which are to be designed for high ductility in order to take care of unexpected lateral forces such as wind and earthquake. Previous investigations reveal that the addition of steel fibres to concrete improves its ductility significantly. Also, due to presence of slab the strength and ductility of the beam increases considerably and ignoring the effect of slab can lead to underestimation of beam capacity and defiance of strong column weak beam concept. The influence of addition of steel fibres on the strength and behaviour of steel fibre reinforced high performance concrete (SFRHPC) interior beam-column-slab joints was investigated experimentally. The specimens were subjected to reverse cyclic loading. The variable considered was the volume fraction of crimped steel fibres i.e., 0%, 0.5% and 1.0%. The results show that the addition of steel fibres improves the first crack load, strength, ductility, energy absorption capacity and initial stiffness of the beam.

Neuroimmunological Aberrations and Cerebral Asymmetry Abnormalities in Schizophrenia: Select Perspectives on Pathogenesis

Ganesan Venkatasubramanian,Monojit Debnath 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.1

Within the wide-ranging gamut of factors that comprise gene-environment interactions postulated to underlie schizophrenia,the crosstalk between environmental factors and feto-maternal immune components has been put forth as one of the importantmechanisms that increase the risk towards schizophrenia in the offspring. Interestingly, immune factors have been shown tocritically modulate the brain development during the prenatal stages. Moreover the past many decades, influential theoreticalpropositions and evidence base (albeit not unequivocally) have compellingly linked prenatal sex hormonal status to criticallyprovoke long lasting immunological changes and subsequently affect developmental programming of cerebral asymmetry inschizophrenia. In this review, we summarize the select perspectives emphasizing the role of neuroimmunoendocrine pathwaysin anomalous cerebral asymmetry in contemporary understanding of schizophrenia pathogenesis.

Effect of hybrid fibers on tension stiffening of reinforced geopolymer concrete

Ganesan, N.,Sahana, R.,Indira, P.V. Techno-Press 2017 Advances in concrete construction Vol.5 No.1

An experimental work was carried out to study the effect of hybrid fiber on the tension stiffening and cracking characteristics of geopolymer concrete (GPC). A total of 24 concentrically reinforced concrete specimens were cast and tested under uniaxial tension. The grade of concrete considered was M40. The variables mainly consist of the volume fraction of crimped steel fibers (0.5 and 1.0%) and basalt fibers (0.1, 0.2 and 0.3%). The load deformation response was recorded using LVDT's. At all the stages of loading after the first cracking, crack width and crack spacing were measured. The addition of fibers in hybrid form significantly improved the tension stiffening effect. In this study, the combination of 0.5% steel fiber and 0.2% basalt fiber gave a better comparison than the other combinations.

Characterization of uncertainties in atmospheric trace gas inversions using hierarchical Bayesian methods

Ganesan, A. L.,Rigby, M.,Zammit-Mangion, A.,Manning, A. J.,Prinn, R. G.,Fraser, P. J.,Harth, C. M.,Kim, K.-R.,Krummel, P. B.,Li, S.,Mü,hle, J.,O&,apos,Doherty, S. J.,Park, S.,Salameh, P. K.,Ste Copernicus GmbH 2014 Atmospheric chemistry and physics Vol.14 No.8

<P>Abstract. We present a hierarchical Bayesian method for atmospheric trace gas inversions. This method is used to estimate emissions of trace gases as well as 'hyper-parameters' that characterize the probability density functions (PDFs) of the a priori emissions and model-measurement covariances. By exploring the space of 'uncertainties in uncertainties', we show that the hierarchical method results in a more complete estimation of emissions and their uncertainties than traditional Bayesian inversions, which rely heavily on expert judgment. We present an analysis that shows the effect of including hyper-parameters, which are themselves informed by the data, and show that this method can serve to reduce the effect of errors in assumptions made about the a priori emissions and model-measurement uncertainties. We then apply this method to the estimation of sulfur hexafluoride (SF6) emissions over 2012 for the regions surrounding four Advanced Global Atmospheric Gases Experiment (AGAGE) stations. We find that improper accounting of model representation uncertainties, in particular, can lead to the derivation of emissions and associated uncertainties that are unrealistic and show that those derived using the hierarchical method are likely to be more representative of the true uncertainties in the system. We demonstrate through this SF6 case study that this method is less sensitive to outliers in the data and to subjective assumptions about a priori emissions and model-measurement uncertainties than traditional methods. </P>

Green Synthesis of Silver Nanoparticles Using the Mushroom Fungus Schizophyllum commune and Its Biomedical Applications

Ganesan Arun,Muthukumarasamy Eyini,Paramasamy Gunasekaran 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.6

Silver nanoparticles, which are small metalliccolloidal particles, ranging 1 ~ 100 nm in size, have severalnano biotechnological applications in medicine, manufacturingand engineering industries. Fungus-mediated synthesis ofsilver nanoparticles is an ecofriendly, green process. Further,extracellular enzymes and proteins elaborated by fungi areinvolved in the synthesis of the silver nanoparticle, whichmakes the downstream processing relatively simpler. In thepresent investigation, Schizophyllum commune, a mushroomfungus, was tested for its ability to synthesize extracellularas well as intracellular silver nanoparticles. When thefungus was challenged with 1 mM silver nitrate, a changein colour of the broth and the mycelium was observed,indicative of extracellular and intracellular synthesis ofsilver nanoparticles. The presence of silver nanoparticleswas confirmed by studying its Surface Plasmon Resonanceabsorption band in the visible wavelength. FTIR spectrumanalysis of the silver nanoparticles indicated the presenceof biomolecules in association with the reduction of silverions. Scanning Electron Microscopic analysis of the silvernanoparticles revealed the nanorange dimensions of boththe extracellular and the intracellular silver nanoparticles. Analysis of biological activities of the silver nanoparticlesdisclosed their significant antibacterial activity againstEscherichia coli, Bacillus subtilis, Klebsiella pneumoniaeand Pseudomonas fluorescens. Additionally, the silvernanoparticles inhibited the growth of the dermatophyticfungal pathogens viz. Trichophyton simii, Trichophytonmentagrophytes and Trichophyton rubrum significantly. Anticancer activity of silver nanoparticles, assayed throughMTT cytotoxicity assay, uncovered that 27.2 and 64%mortality could be obtained in Human Epidermoid LarynxCarcinoma (HEP -2) cell lines at concentrations between10 and 100 μg/mL, respectively. The results obtained indicatethat Schizophyllum commune is capable of synthesizingsilver nanoparticles in shaken broth cultures (120 rpm) at25 ± 2°C and pH 7.

1H-NMR-based Metabolomics Studies of the Toxicity of Mesoporous Carbon Nanoparticles in Zebrafish (Danio rerio )

Ganesan Raja,김시원,윤다혜,윤창신,김석만 대한화학회 2017 Bulletin of the Korean Chemical Society Vol.38 No.2

Mesoporous carbon nanoparticles (MCNs) have been applied in a variety of drug/gene carriers. In addition to their potential benefits, many studies of their potential toxicity have been reported, showing the limitations of metabolic contextualization. In this study, we conducted1H-nuclear magnetic resonance (NMR) profiling combined with statistical methods such as orthogonal partial least squares discriminant analysis and Pearson correlation analysis to assess metabolic alterations in the whole body of zebrafish (Danio rerio) in the presence of various concentrations of MCNs. The MCN exposure influenced numerous metabolites in energy metabolism (e.g., metabolites involved in glycolysis and tricarboxylic acid cycle) and disturbed the balance of neurotransmitters and osmoregulators. Our findings demonstrate the potential applicability of using a metabolomics approach to determine underlying metabolic disturbances caused by MCNs.

Shape Effect on Electrochemical Energy Storage Performance of Nanosized Copper Germanium Selenide Particles

Ganesan Vinoth,Kim Jinkwon 대한화학회 2021 Bulletin of the Korean Chemical Society Vol.42 No.4

Colloidal Cu2GeSe3 nanosheets (NSs) (0.5–1.5 μm) and Cu2GeSe3 nanoparticles (NPs) (8–10 nm) were synthesized for electrochemical performance comparison. The galvanostatic measurements show the maximum capacitance of 118 F/g and 77 F/g for Cu2GeSe3 NSs and NPs, respectively. Each type of nanomaterials exhibits shape dependence in its capacitance reduction behavior with increasing current density due to differences in surface area and electrical conductivity. The cyclic stability tests for Cu2GeSe3 NSs showed a capacity retention of about 90% after 1000 cycles.

Inexpensive electrochemical synthesis of nickel iron sulphides on nickel foam: super active and ultra-durable electrocatalysts for alkaline electrolyte membrane water electrolysis

Ganesan, P.,Sivanantham, A.,Shanmugam, S. Royal Society of Chemistry 2016 Journal of materials chemistry. A, Materials for e Vol.4 No.42

<P>Efficient and durable electrocatalysts for water splitting (both the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER)) are required for the replacement of expensive noble metal-based catalysts used in water electrolysis devices. Herein, we describe the inexpensive synthesis of electrochemically deposited nickel iron sulphides on nickel foam (NiFeS/NF) and their use as highly efficient bi-functional water splitting catalysts that can meet the current energy demands. The NiFeS/NF electrocatalysts exhibited low overpotentials of approximately 231 mV for the OER and 180 mV for the HER in 1 M KOH. Moreover, the NiFeS/NF electrocatalysts exhibited a turnover frequency of one order of magnitude higher than those of state-of-the-art noble metal catalysts (RuO2 and Pt/C) for the OER and HER. In addition to this excellent activity, the bi-functional catalyst also exhibited an outstanding OER and HER electrode stability for over 200 h with minimal loss in activity. Further, it can be directly used in the practical application of alkaline electrolyte membrane water electrolysis. The high performance, prolonged electrode stability, and facile synthesis as an adherent coating on nickel foam suggest that NiFeS/NF electrocatalysts might be suitable for use as alternative commercially viable catalysts.</P>