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        • KCI등재

          Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study

          Elena Maria Yubero-Serrano,Javier Delgado-Lista,Patricia Pena-Orihuela,Pablo Perez-Martine,Francisco Fuentes,Carmen Marin,Isaac Tunez,Francisco Jose Tinahones,Francisco Perez-Jimenez,Helen M Roche,Jos 생화학분자생물학회 2013 Experimental and molecular medicine Vol.45 No.6

          Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of OxS in MetS patients. In this comparative cross-sectional study from the LIPGENE cohort, a total of 91 MetS patients (43 men and 48women; aged between 45 and 68 years) were divided into four groups based on the number of MetS components: subjects with 2, 3, 4 and 5 MetS components (n¼20, 31, 28 and 12, respectively). We measured ischemic reactive hyperemia (IRH),plasma levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), total nitrite, lipid peroxidation products (LPO), hydrogen peroxide (H2O2), superoxide dismutase (SOD) and glutathione peroxidase (GPx) plasma activities. sVCAM-1, H2O2 and LPO levels were lower in subjects with 2 or 3 MetS components than subjects with 4 or 5 MetS components. IRH and total nitrite levels were higher in subjects with 2 or 3 MetS components than subjects with 4 or 5 MetS components. SOD and GPx activities were lower in subjects with 2 MetS components than subjects with 4 or 5 MetS components. Waist circumference,weight, age, homeostatic model assessment-b, triglycerides (TGs), high-density lipoprotein and sVCAM-1 levels were significantly correlated with SOD activity. MetS subjects with more MetS components may have a higher OxS level. Furthermore, association between SOD activity and MetS components may indicate that this variable could be the most relevant OxS biomarker in patients suffering from MetS and could be used as a predictive tool to determine the degree of the underlying OxS in MetS.

        • SCIESCOPUSKCI등재

          Extension of the Rotating Planar Waveguide Model to Formation of Interference Patterns in Optical Fibers

          Pena-Garcia, Antonio,Perez-Ocon, Francisco,Jimenez, Jose Ramon Optical Society of Korea 2011 Journal of the optical society of Korea Vol.15 No.2

          After the successful extension of the rotating planar waveguide model to Wave Optics, where a clear identification between the angular velocity of one hypothetical waveguide and the phase differences between two points on the path of one bounded mode was found, an application of the model to explain the interference theory is presented. We demonstrate that, for two bounded modes to create an interference pattern, a constrain to the relative parameters among both is imposed by the fiber optics. This result, not reported in the literature up to date, provides a new horizon to understand the interaction light-light when propagated within optical fibers.

        • KCI등재

          Extension of the Rotating Planar Waveguide Model to Formation of Interference Patterns in Optical Fibers

          Antonio Pena-Garcia,Francisco Pérez-Ocón,José Ramón Jiménez 한국광학회 2011 Journal of the optical society of Korea Vol.15 No.2

          After the successful extension of the rotating planar waveguide model to Wave Optics, where a clear identification between the angular velocity of one hypothetical waveguide and the phase differences between two points on the path of one bounded mode was found, an application of the model to explain the interference theory is presented. We demonstrate that, for two bounded modes to create an interference pattern, a constrain to the relative parameters among both is imposed by the fiber optics. This result, not reported in the literature up to date, provides a new horizon to understand the interaction light-light when propagated within optical fibers.

        • SCIESCOPUSKCI등재

          Mechanical properties related to the microstructure of seven different fiber reinforced composite posts

          de la Pena, V?ctor Alonso,Darriba, Iria L,Valea, Martin Caserio,Rivera, Francisco Guitian The Korean Academy of Prosthodonitics 2016 The Journal of Advanced Prosthodontics Vol.8 No.6

          PURPOSE. The aim of this in vitro study was to evaluate the mechanical properties (bending strength and hardness) of seven different fiber reinforced composite posts, in relation to their microstructural characteristics. MATERIALS AND METHODS. Two hundred eighty posts were divided into seven groups of 40, one group for each type of post analyzed. Within each group, 15 posts were subjected to three-point bending strength test, 15 to a microhardess meter for the Knoop hardness, and 10 to Scanning Electron Microscope in order to determine the diameter of the fibers and the percentage of fibers embedded in the matrix. To compare the flexural strength in relation to the type of fiber, matrix, and the hardness of the posts, a Kruskal-Wallis H test was used. The Jonckheere-Terpstra test was used to determine if the volume percent of fibers in the post influenced the bending strength. RESULTS. The flexural strength and the hardness depended on the type of fibers that formed the post. The lower flexural strength of a post could be due to deficient bonding between the fiber and the resin matrix. CONCLUSION. According to the results, other factors, besides the microstructural characteristics, may also influence the mechanical properties of the post. The feature that has more influence on the mechanical properties of the posts is the type of fiber.

        • KCI등재

          Operation load estimation of chain-like structures using fiber optic strain sensors

          Armen Derkevorkian,Francisco Pena,Sami F. Masri,W. Lance Richards4 국제구조공학회 2017 Smart Structures and Systems, An International Jou Vol.20 No.3

          The recent advancements in sensing technologies allow us to record measurements from target structures at multiple locations and with relatively high spatial resolution. Such measurements can be used to develop data-driven methodologies for condition assessment, control, and health monitoring of target structures. One of the state-of-the-art technologies, Fiber Optic Strain Sensors (FOSS), is developed at NASA Armstrong Flight Research Center, and is based on Fiber Bragg Grating (FBG) sensors. These strain sensors are accurate, lightweight, and can provide almost continuous strainfield measurements along the length of the fiber. The strain measurements can then be used for real-time shape-sensing and operational load-estimation of complex structural systems. While several works have demonstrated the successful implementation of FOSS on large-scale real-life aerospace structures (i.e., airplane wings), there is paucity of studies in the literature that have investigated the potential of extending the application of FOSS into civil structures (e.g., tall buildings, bridges, etc.). This work assesses the feasibility of using FOSS to predict operational loads (e.g., wind loads) on chain-like structures. A thorough investigation is performed using analytical, computational, and experimental models of a 4-story steel building test specimen, developed at the University of Southern California. This study provides guidelines on the implementation of the FOSS technology on building-like structures, addresses the associated technical challenges, and suggests potential modifications to a load-estimation algorithm, to achieve a robust methodology for predicting operational loads using strain-field measurements.

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