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RISS 인기검색어
- 검색키워드
- 저자 : Felipe Fregni (검색결과 3 건)
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한수정(Soo Jeong Han),Felipe Fregni 제어로봇시스템학회 2012 제어로봇시스템학회 합동학술대회 논문집 Vol.2012 No.7
We propose to evaluate cortical activity in athletes with concussions by using single and paired pulse transcranial magnetic stimulation and also by assessing the effects of a single session of transcranial direct current stimulation on cortical excitability. Using non-invasive brain techniques is a feasible and a safe way to assess the effects of concussion as to determine whether treatment approaches are necessary. It will thus directly impact the military by enhancing the understanding of concussion and by providing a possible physiologic tool for diagnosis to explore.
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Matheus Soldatelli,Álvaro de Oliveira Franco,Felipe Picon,Juliana Ávila Duarte,Ricardo Scherer,Janete Bandeira,Maxciel Zortea,Iraci Lucena da Silva Torres,Felipe Fregni,Wolnei Caumo 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.1
Background: Resting-state functional connectivity (rs-FC) may aid in understanding the link between painmodulating brain regions and the descending pain modulatory system (DPMS) in fibromyalgia (FM). This study investigated whether the differences in rs-FC of the primary somatosensory cortex in responders and non-responders to the conditioned pain modulation test (CPM-test) are related to pain, sleep quality, central sensitization, and the impact of FM on quality of life. Methods: This cross-sectional study included 33 females with FM. rs-FC was assessed by functional magnetic resonance imaging. Change in the numerical pain scale during the CPM-test assessed the DPMS function. Subjects were classified either as non-responders (i.e., DPMS dysfunction, n = 13) or responders (n = 20) to CPM-test. A generalized linear model (GLM) and a receiver operating characteristic (ROC) curve analysis were performed to check the accuracy of the rs-FC to differentiate each group. Results: Non-responders showed a decreased rs-FC between the left somatosensory cortex (S1) and the periaqueductal gray (PAG) (P < 0.001). The GLM analysis revealed that the S1-PAG rs-FC in the left-brain hemisphere was positively correlated with a central sensitization symptom and negatively correlated with sleep quality and pain scores. ROC curve analysis showed that left S1-PAG rs-FC offers a sensitivity and specificity of 85% or higher (area under the curve, 0.78, 95% confidence interval, 0.63–0.94) to discriminate who does/does not respond to the CPM-test. Conclusions: These results support using the rs-FC patterns in the left S1-PAG as a marker for predicting CPM-test response, which may aid in treatment individualization in FM patients.
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A Preliminary Study on qEEG in Burn Patients With Chronic Pruritus
Fiorella K. Miraval,Vivian L. Shie,Leon Morales-Quezada,Carolina Santiago,Bianca Fernandes-Marcondes,Deborah Nadler,Colleen M. Ryan,Jeffrey C. Schneider,Felipe Fregni 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.4
Objective To explore and determine the reorganizational changes in the cortical neural circuits associated with pruritis, this study was undertaken to compare the electroencephalography (EEG) changes in burn patients having primary symptoms of chronic itching (pruritis) and their paired healthy subjects. Methods Eight subjects were recruited for this exploratory pilot study: 4 patients with pruritus after burn injury matched by gender and age with 4 healthy subjects. EEG recordings were analyzed for absolute alpha, low beta, high beta, and theta power for both groups. Results The mean age of the burn patients was 41.75 years; while the mean age for the matched healthy subjects was 41.5 years. All subjects were male. A decreased alpha activity was observed in the occipital channels (0.82 vs. 1.4; p=0.01) and a decreased low beta activity in the frontal area (0.22 vs. 0.4; p=0.049) in eyes closed conditions. An overall decreased theta trend was observed in both the eyes open and eyes closed conditions in burn patients, compared to healthy individuals.Conclusion This preliminary study presents initial evidence that chronic pruritus in burn subjects may be associated with brain reorganizational changes at the cortical level characterized by an EEG pattern.
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