Inquire into the Development of Politics and Economy in the Middle East

( Fan Di ),( Ui Sup Shin ) 한국외국어대학교 중동연구소 2008 중동연구 Vol.27 No.2

Under the current globalizing process, the Middle East political system reform is an inevitable historical trend, but it will not be smooth. The economic reformative approaches are necessary and important as well as the political reform. The economic reformation and cooperation in this region will make a breakthrough first in the Gulf region with the efforts of GCC. The Arab free trade region will achieve new successes, and continue to play an active role in this area. The economic and political reformative system in the Middle East are expected to achieve greater development in the middle of globalizing 21st century and to enhance their status and role in the world.

Preparation of 5-fluorouracil-loaded Nanoparticles and Study of Interaction with Gastric Cancer Cells

Fan, Yu-Ling,Fan, Bing-Yu,Li, Qiang,Di, Hai-Xiao,Meng, Xiang-Yu,Ling, Na Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

Aims: To prepare 5-fluorouracil (5-Fu) nanoparticles with higher encapsulation efficiency and drug loading, and then investigate interaction with the SGC-7901 gastric cancer cell line. Materials and Methods: Prescription was optimized by orthogonal experiments, the encapsulation efficiency and loading capacity were tested by high-performance liquid chromatography, and inhibition of proliferation by 5-Fu nanoparticles and 5-Fu given to cells for 24, 48 and 72 hours was investigated by methyl thiazolyl tetrazolium assay (MTT). In addition, 5-Fu nanoparticles were labeled by fluorescein isothiocyanate (FITC), and absorption into cells was tested by flow cytometry. Results: The optimal conditions for preparation were concentrations of 5-Fu of 5mg/ml, of $CaCl_2$ of 60 mg/ml and of chitosan of 2 mg/ml. With a stirring speed of 1200rpm, encapsulation efficiency of 5-Fu nanoparticles was $55.4{\pm}1.10%$ and loading capacity was $4.22{\pm}0.14%$; gastric cancer cells were significantly inhibited by 5-Fu nanoparticles in a time and concentration dependent manner, and compared to 5-Fu with slower drug release, in a certain concentration range, inhibition with 5-Fu nanoparticles was stronger. 5-Fu nanoparticles were absorbed by the cells in line with the concentration. Conclusions: 5-Fu nanoparticles can inhibit growth of gastric cancer cells in vitro to a greater extent than with 5-Fu with good adsorption characteristics, supporting feasibility as a carrier.

Helicity-dependent photovoltaic effect on Bi and Bi/Ag thin films

Di FAN,Hirotaka ISHIHARA,Ryota AKIYAMA,Rei HOBARA,Akari TAKAYAMA,Shuji HASEGAWA 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

Liver metabolic perturbations of heat-stressed lactating dairy cows

Fan, Caiyun,Su, Di,Tian, He,Li, Xiaojiao,Li, Yu,Ran, Lei,Hu, Ruiting,Cheng, Jianbo Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.8

Objective: The objective of the present study was to elucidate the mechanism underlying liver metabolic perturbations in dairy cows exposed to heat stress (HS). Methods: Liquid chromatography massabl spectrometry was used to analyze metabolic differences in livers of 20 dairy cows, with and without exposure to HS. Results: The results revealed 33 potential metabolite candidate biomarkers for the detection of HS in dairy cows. Fifteen of these metabolites (glucose, lactate, pyruvate, acetoacetate, ${\beta}$-hydroxybutyrate, fumaric acid, citric acid, choline, glycine, proline, isoleucine, leucine, urea, creatinine, and orotic acid) were previously found to be potential biomarkers of HS in plasma or milk, discriminating dairy cows with and without HS. Conclusion: All the potential diagnostic biomarkers were involved in glycolysis, amino acid, ketone, tricarboxylic acid, or nucleotide metabolism, indicating that HS mainly affected energy and nucleotide metabolism in lactating dairy cows.

在韩中国留学生使用韩语名字形式喜好度调查研究: 以釜山P大学中国留学生为对象

樊杰(Fan, Jie),金炫兑,(Kim, Hyun-Tae),王彦迪(Wang, Yan-Di) 대한중국학회 2021 중국학 Vol.76 No.-

人名是人类社交中的个体标志,它不仅是个语言符号,更是各国历史,文化的结晶。近年来,随着中韩两国的交流日益频繁,越来越多的中国人受到“韩流”的影响,选择来韩国留学。为了保证留学生在韩国学习和生活,取一个合适的韩语名字,既是留学生了解和亲近韩国文化的第一步,还有助于留学生对韩语产生亲切感,融入当地的环境。中韩同属“汉字文化圈”,以前把中国人名字翻译成韩语时大多是选择汉字相对应的韩语标记,而现在是按照“外来语标记法”来进行标记。但实际上这并没有得到很好的遵守,外国人的韩语名字混译的情况一直存在。本文通过对釜山P大学的211位留学生使用的韩语名字形式喜好度进行调查分析,得出的结果是表明中韩两国有汉字为纽带,在为中国留学生取名时也应考虑到文化的因素,不必要像标记欧美国家人的名字一样按发音来进行标记。 Name is an individual symbol in human society. It is not only a language symbol, but also the crystallization of the history and culture of various countries. In recent years, with the increasingly frequent exchanges between China and South Korea, more and more Chinese people are influenced by the “Korean Wave” and choose to study in South Korea. A proper Korean name can help international students learn Korean better, understand Korean culture, and adapt to Korean life and so on. Both China and South Korea belong to “the Cultural Sphere of Chinese Characters”. In the past, when Chinese names were translated into Korean, most of them chose Korean symbols corresponding to Chinese characters, but now they are marked according to the “Loanword orthography”. But in fact, this is not binding, and can not be well observed. Foreigners’ Korean names have always translation mixed. This paper investigates and analyzes the preference of Korean name forms used by 211 international students of P University in Busan. The result is that China and South Korea are both belong to Chinese cultural circles. When naming Chinese students, it is not necessary to mark according to the Loanword orthography like translating the names of European and American. At the same time, cultural factors should also be considered for translation.

Sulfakinin inhibits activity of digestive enzymes in the brown planthopper, Nilaparvata lugens

Guo Di,Zhang Su,Zhang Yi-Jie,Ma Jun-Yu,Gao Cong-Fen,Wu Shun-Fan 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

In animals, feeding can regulate release of digestive enzymes. Digestive enzymes are produced and released in response to specific ratios of nutrients, so the quality and quantity of food ingested are important factors in the secretion and activity of digestive enzymes. In general, the enzyme activity and secretion in the fed insects are relatively higher than that in the unfed insects. Neuropeptides and peptide hormones are important regulators of enzyme activity. In several insects, the neuropeptide sulfakinin (SK) is known to be a regulator of feeding and digestion similar to cholecystokinin in mammals. However, the roles of diet and SK in regulation of activity of digestive enzymes in the important pest insect, the brown planthopper (Nilaparvata lugens), are unknown. In this study, we identified six genes encoding different digestive enzymes and cloned three of these. We found that enzymatic activity and transcriptional levels of digestive enzymatic activity genes were upregulated by refeeding animals for 5 h after 24 h starvation. Furthermore, injection of N. lugens SK reduces digestive enzyme activity and leads to a downregulation of digestive enzyme gene transcripts. This study provides new views into the action of diet and SK in regulation of digestive enzymes in (hemimetabolous) insects. Taken together with the roles of SK in inducing satiety, our data strongly suggest that SK signaling is important in regulation of food ingestion and processing.

Fluorescent Nitrogen-Doped Carbon Dots via Single-Step Synthesis Applied as Fluorescent Probe for the Detection of Fe3+ Ions and Anti-Counterfeiting Inks

Chonghui Fan,Kelong Ao,Pengfei Lv,Jiancheng Dong,Di Wang,Yibing Cai,Qufu Wei,Yang Xu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.08

Fluorescent nitrogen-doped carbon dots (N-CDs) with excellent stability were prepared via single-step hydrothermal carbonization of citric acid (CA) and ethylenediamine (EDA). The as-prepared N-CDs emit blue fluorescence under the excitation of 365 nm and have a size distribution of 2.80 ffi 0.47 nm with benign size effect. The structure and morphology were further characterized by X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) spectroscopy. It was found that the surface of the N-CDs was successfully functionalized, which presented water solubility and chelation with Fe3+. XRD results display a diffraction peak at 23.9 ℃, which corresponds to the (002) interlayer spacing of a graphitic structure revealing an amorphous carbon phase. Furthermore, due to good sensitivity, N-CDs were used as probes for Fe3+ detection. The low limit of detection of 0.6 μM as a fluorescence probe was successfully obtained based on the linear relationship between (F0 - F) / F0 and concentration of Fe3+ ions. Besides the satisfactory fluorescence, PVA/N-CDs membranes and fluorescent inks demonstrate potential for anti-counterfeiting applications due to its characteristic flexibility, transparency, removability and invisibility under ambient lighting.

Sample Preparation and Stability of Human Serum and Urine Based on HPLC-DAD for Metabonomics Studies

Yunliu Fan,Xiaoming Sun,Duolong Di,Yuxiang Feng,Fengling Jin 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.7

Many literatures focus on the biological relevance and the identification of biomarkers for disease activity assessment while less attention has been paid to the development of standard procedures for sample preparation and storage based on liquid chromatography technique. The influencing factors including protein precipitation, storage temperature, storage time, and reconstitution by ultra pure water were analyzed employing HPLCDAD. The effects were investigated from five participants over three months by principal components analysis (PCA) and the values of percent changes (PC). The samples with protein precipitation might slow the rate of bacterial enzymatic conversion. After protein precipitation, the average PC of urine samples (0.136 ± 0.013, n = 5) is relatively less than that of the serum samples (0.173 ± 0.026, n = 5) for three months. Minimal effects on metabolic profiles of serum and urine (PC < 0.15) are reasonable for metabolomic studies after protein precipitation and storage at −20 oC for two months.

Genome-wide DNA methylation pattern in a mouse model reveals two novel genes associated with Staphylococcus aureus mastitis

Wang, Di,Wei, Yiyuan,Shi, Liangyu,Khan, Muhammad Zahoor,Fan, Lijun,Wang, Yachun,Yu, Ying Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.2

Objective: Staphylococcus aureus (S. aureus) is one of the major microorganisms responsible for subclinical mastitis in dairy cattle. The present study was designed with the aim to explore the DNA methylation patterns using the Fluorescence-labeled methylation-sensitive amplified polymorphism (F-MSAP) techniques in a S. aureus-infected mouse model. Methods: A total of 12 out-bred Institute of Cancer Research female mice ranging from 12 to 13 weeks-old were selected to construct a mastitis model. F-MSAP analysis was carried out to detect fluctuations of DNA methylation between control group and S. aureus mastitis group. Results: Visible changes were observed in white cell counts in milk, percentage of granulocytes, percentage of lymphocytes, CD⁴⁺/CD⁸⁺ ratio (CD⁴⁺/CD⁸⁺), and histopathology of mice pre- and post-challenge with S. aureus. These findings showed the suitability of the S. aureus-infected mouse model. A total of 369 fragments was amplified from udder tissue samples from the two groups (S. aureus-infected mastitis group and control group) using eight pairs of selective primers. Results indicated that the methylation level of mastitis mouse group was higher than that in the control group. In addition, NCK-associated protein 5 (Nckap5) and transposon MTD were identified to be differentially methylated through secondary polymerase chain reaction and sequencing in the mastitis group. These observations might play an important role in the development of S. aureus mastitis. Conclusion: Collectively, our study suggests that the methylation modification in Nckap5 and transposon MTD might be considered as epigenetic markers in resistance to S. aureus-infected mastitis and provided a new insight into S. aureus mastitis research in dairy industry and public health.

Multilingual Computer Processing System

Hu Fan Jin,Ru Lin Liu,Ri Di Ga,Zhung Rao Wu 대한전자공학회 1991 International Conference on Electronics, Informati Vol.1 No.1