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      • KCI등재

        Blind Signal Separation Method Based Machining Error Decomposition

        Fa-Ping Zhang,Di Wu,Yan Yan,Shahid Ikramullah Butt 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.2

        In view of the current error separation method cannot successfully separate the dissimilar systematic error components from the whole surface machining data, a method for machining errors decomposition based on blind signal separation is proposed which can distinguish those dissimilar systematic error components. Firstly, the error transfer model to describe the errors synthesizing from the single error component caused by corresponding individual error source to the synthesis machining surface error is conducted. To determine the number of the systematic error components, the principal component analysis (PCA) method is used. Then according to the theory of blind source separation, negative entropy based fixed point algorithm is proposed to fulfill the machining error components separation, which can realize the separation of the systematic error components even in close frequency scale. Finally, a shaft surface finish turning data and a flat surface milling data are used as examples to verify the proposed method. The result shows that the proposed error separation method can effectively realize the machining error separation in close frequency scale.

      • KCI등재

        WEIGHTED EVIDENTIAL FUSION METHOD FOR FAULT DIAGNOSIS OF MECHANICAL TRANSMISSION BASED ON OIL ANALYSIS DATA

        Yan Shu-fa,Ma Biao,Zheng Chang-song,Chen Man 한국자동차공학회 2019 International journal of automotive technology Vol.20 No.5

        Condition monitoring (CM) and fault diagnosis are critical for the stable and reliable operation of mechanical transmissions. Mechanical transmission wear, which leads to changes in the physicochemical properties of the lubrication oil and thus severe wear, is a slow degradation process that can be monitored by oil analysis, but the actual degradation degree is difficult to evaluate. To solve this problem, we propose a new weighted evidential data fusion method to better characterize the degradation degree of the mechanical transmission through the fusion of multiple CM datasets from oil analysis. This method includes weight allocation and data fusion steps that lead to a more accurate data-based fault diagnostic result for CM. First, the weight of each evidence is modeled with a weighted average function by measuring the relative scale of the permutation entropy from each CM dataset. Then, the multiple CM datasets are fused by the Dempster combination rule. Compared with other evidential data fusion methods, the proposed method using the new weight allocation function seems more reasonable. The rationality and superiority of the proposed method were evaluated through a case study involving an oilbased CM dataset from a power-shift steering transmission.

      • KCI등재

        Synthesis and Structural Studies of an Organic Complex and its Association with BSA

        Fa-Yan Meng,Jin-Mei Zhu,Li Wang,Xue-Ping Zhong,Li-Xi Liang,Sheng-Rong Yu,Cui-Wu Lin 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.7

        The self-assembly of one novel organic complex based on chlorogenic acid (HCA) and 2,2'-bipyridine (2,2'-bipy) has been synthesized and characterized. The complex achieved by hydrogen-bonding interactions,adopted a 1:1 stoichiometry in a solid state. The proton transfer occurred from the carboxyl oxygen to the aromatic nitrogen atom to form salts CA·(2,2'-Hbipy), the 2,2'-Hbipy molecule individually occupies the pseudo-tetragonum that is formed with CA. In this paper, the interactions of CA·(2,2'-Hbipy) with bovine serum albumin (BSA) were studied by fluorescence spectrometry. For CA·(2,2'-Hbipy), HCA and 2,2'-bipy,the average quenching constants for BSA were 2.4384 × 10^4, 4.653 × 10^3, and 3.059 × 10^3 L·mol^−1, respectively. The mechanism for protein fluorescence quenching is apparently governed by a static quenching process. The Stern-Volmer quenching constants and corresponding thermodynamic parameters ΔH, ΔG and ΔS were calculated. The binding constants and the number of binding sites were also investigated. The conformational changes of BSA were observed from synchronous fluorescence spectra.

      • SCOPUSKCI등재

        Synthesis and Structural Studies of an Organic Complex and its Association with BSA

        Meng, Fa-Yan,Yu, Sheng-Rong,Liang, Li-Xi,Zhong, Xue-Ping,Wang, Li,Zhu, Jin-Mei,Lin, Cui-Wu Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.7

        The self-assembly of one novel organic complex based on chlorogenic acid (HCA) and 2,2'-bipyridine (2,2'-bipy) has been synthesized and characterized. The complex achieved by hydrogen-bonding interactions, adopted a 1:1 stoichiometry in a solid state. The proton transfer occurred from the carboxyl oxygen to the aromatic nitrogen atom to form salts CA${\cdot}$(2,2'-Hbipy), the 2,2'-Hbipy molecule individually occupies the pseudo-tetragonum that is formed with CA. In this paper, the interactions of CA${\cdot}$(2,2'-Hbipy) with bovine serum albumin (BSA) were studied by fluorescence spectrometry. For CA${\cdot}$(2,2'-Hbipy), HCA and 2,2'-bipy, the average quenching constants for BSA were $2.4384{\times}10^4$, $4.653{\times}10^3$, and $3.059{\times}10^3\;L{\cdot}mol^{-1}$, respectively. The mechanism for protein fluorescence quenching is apparently governed by a static quenching process. The Stern-Volmer quenching constants and corresponding thermodynamic parameters ${\Delta}$H, ${\Delta}$G and ${\Delta}$S were calculated. The binding constants and the number of binding sites were also investigated. The conformational changes of BSA were observed from synchronous fluorescence spectra.

      • SCOPUSKCI등재

        Syntheses, Crystal Structures, and Spectral Properties of Two Coordination Compounds Based on 1,2-Bis(benzimidazolyl)benzene

        Meng, Fa-Yan,Jiang, Bing-Li,Lin, Cui-Wu,Wang, Li,Tan, Xiao-He Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.3

        Two new benzimidazolyl-containing complexes have been synthesized by reactions of $Cu^{II}$ salts and 1,2-bis(benzimidazolyl) benzene ($H_2bbbz$) with two different dicarboxylate ligands. When phthalate acid ($H_2pt$) was employed as secondary ligand, a 0D molecular complex Cu$(H_2bbbz)(pt){\cdot}(H_2pt)$ (1)was furnished and when the secondary ligand was instead by a linear bridging ligand of terephthalic acid ($H_2tp$) a 1D zipper-like coordination polymer $[Cu(H_2bbbz)(tp){\cdot}2(C_2H_5OH){\cdot}H_2O]_n$ (2) was obtained, suggesting the structure-direction effect of the secondary dicarbxylate ligand. The preliminary investigation on the spectral properties of the complexes was also presented.

      • SCIESCOPUSKCI등재
      • KCI등재

        A Combination of a Microemulsion and a Phospholipid Complex for Topical Delivery of Oxymatrine

        Fa-Hao Cao,Wu-Qing OuYang,Yan-Ping Wang,Peng-Fei Yue,Shu-Peng Li 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.4

        Oxymatrine (OMT), a water-soluble drug, has a very low oral bioavailability because of its low membrane permeability and its biotransformation in the gastrointestinal tract. Formulated as an oxymatrine-phospholipid complex (OMT-PLC) can improve the lipid solubility and effectiveness of OMT. The purpose of this study was to explore the utility of the combination of a microemulsion and an OMT-PLC as a topical delivery vehicle for enhancing the absorption and efficacy of OMT. The solubility of OMT-PLC was determined and phase diagrams of microemulsions were constructed. Various microemulsion formulations were developed and characterized by their physicochemical properties, and their in vitro and in vivo permeability through skin. An optimal microemulsion (ME4), which presented as spherical droplets and consisted of 10.0% OMT-PLC, 8.0% isopropyl myristate, 30.0% Cremophor RH40/polyethylene glycol 400 (1:1) and 52.0% water, was selected. It possessed an average droplet size of 32.4 nm, a low viscosity of 113.7 mPa · s, and a high cloud point of 88°C. Compared to the control solution, ME4 provided better skin permeability in vitro and a higher retention ratio of OMT in skin in vivo. Moreover, ME4 significantly enhanced the antiproliferative activity of OMT on scar fibroblasts. These results indicate that the combination of a microemulsion and a phospholipid complex represents an effective vehicle for topical delivery of OMT.

      • KCI등재

        동북아경제합작여전망(東北亞經濟合作與展望)

        엄법선 중국학연구회 2000 中國學硏究 Vol.19 No.-

        세계 경제의 지속적인 발전과 국제무역·국제투자의 끊임없는 확대에 따라 세계 각국의 경제적 연계는 더욱 밀접하게 되었다. 어떠한 국가의 경제발전도 국제시장의 자원과 자금, 기술, 그리고 노동력 등과 같은 생산요소의 자유로운 흐름에서 벗어날 수 없을 것이다. 동북아시아는 일반적으로 일본과 한국, 북한, 몽골, 중국의 동북부 지역, 그리고 러시아의 시베리아 원동(遠東) 지역을 가리킨다. 최근 동북아 지역의 국가관계에 낙관적인 변화가 발생했다. 동북아 지역의 각 국가는 정치적으로 분만 아니라 경제적으로도 상호협력할 수 있는 조건을 갖추고 있다. 동북아 지역 국가의 경제 발전은 자연적인 기초 위에 서로의 우수한 점들을 상호보완함으로써 각자의 잠재력과 우수성을 발휘할 수 있으며 아울러 각자의 부족한 면을 극복할 수 있을 것이다. 이로써 각국이 모두 경제협력의 장점을 취할 수 있는 것이다. 경제협력의 발전에 따라 정치관계도 분명 부단히 개선될 것이며 이로써 나아가 동북아 지역의 경제적 번영과 정치적 안정이 실현될 것이다. 동북아지역의 경제협력은 유럽공동체 모델과 동남아 모델 등 여타 지역의 경험을 교훈으로 삼아야 한다. 그에 있어서 주의해야 할 문제는 쉬운 것부터, 작은 것부터 시작하여 어렵고 큰 것으로 나아감으로써 점차적인 발전을 꾀해야 한다는 점이다. 동북아의 경제협력은 정부의 간섭과 시장 메커니즘이 결합된 모델을 갖추어야 하며 민간기업의 협력 뿐 아니라 정부의 도움 또한 무시해서는 안될 것이다. 동북아 지역 경제를 개발하는 데 있어 또한 주의해야 할 문제는 환경보호 문제이다. 동북아 지역의 경제협력은 공동의 이익에서 출발해야 하며 호혜와 상호이익의 원칙을 견지해야 한다. 이로써 동북아가 아시아 태평양 시장을 이끌어 나가고, 자원개발과 기술합작에 의거하여 국경을 초월한 생산요소의 우월한 합작을 이끌어 내야 한다. 이를 통해 지역 내의 우수한 산업과 특색 있는 경제가 신속하게 형성되고 발전할 수 있을 것이다.

      • KCI등재

        A Modified Static Contention Free Single Phase Clocked Flip-flop Design for Low Power Applications

        Jin-Fa Lin,Ming-Yan Tsai 대한전자공학회 2018 Journal of semiconductor technology and science Vol.18 No.5

        A modified static contention free truesingle-phase clocked (TSPC) flip-flop with 23- transistor only is proposed in this paper. It is optimized by a recently presented TSPC based flipflop design and achieves circuit simplification. The optimized measure leads to a new flip-flop design featuring better and various performances. Based on post-layout simulation results using the TSMC CMOS 40nm technology, the proposed design outperforms the conventional TGFF by 49.2% in energy consumption (at 0% data activity switching) with the same layout area.

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