Surgical Endoscopy, Education and Accreditation in Hong Kong

Enders Kwok-wai Ng 대한외과학회 2014 대한외과학회 학술대회 초록집 Vol.2014 No.11

IL-8 gene polymorphism in acute biliary and non biliary pancreatitis

Ender Anilir,Filiz Ozen,Ibrahim Halil Yildirim,Ibrahim Ali Ozemir,Can Ozlu,Orhan Alimoglu 한국간담췌외과학회 2017 Annals of hepato-biliary-pancreatic surgery Vol.21 No.1

Backgrounds/Aims: Inflammatory mediators of the innate immune response play fundamental roles in the pathogenesis of acute pancreatitis. The correlation between interleukin-8 (IL-8) gene polymorphism with types of acute pancreatitis and severity of pancreatitis, was evaluated in this study. Methods: According to the diagnostic criteria, 176 patients with acute pancreatitis were grouped into biliary (n=83) and nonbiliary pancreatitis (n=93). Healthy blood donors (n=100) served as controls. Serum alanine transaminase, aspartate transaminase, total and direct bilirubin, amylase, lypase, white blood cell count and c-reactive protein levels were evaluated to correlate with IL-8 rs4073 (-251T/A) polymorphism, which was analyzed using a real-time polymerase chain reaction method with melting point analysis. Results: The IL-8 AA genotype was detected with a significantly higher frequency among the patients with acute biliary pancreatitis having higher alanine transaminase levels than the median range. Homozygote alleles were significantly higher among patients with acute biliary pancreatitis having amylase levels higher than the median range. Conclusions: Determination of the frequency of IL-8 polymorphism in acute pancreatitis is informative and provides further evidence concerning the role of IL-8 in laboratory tests.

Revolution and Refinement of Surgical Techniques for Living Donor Partial Liver Transplantation

Ender Dulundu,Yasuhiko Sugawara,Masatoshi Makuuchi 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.6

Living donor liver transplantation (LDLT) was first successfully performed on a child in 1990 and the Shinshu group performed the same procedure on an adult for the first time in 1994. Over the past few years adult LDLT has been increasing worldwide because of the severe shortage of cadaveric organs, especially in locations where the transplantation of organs from brain-dead donors is rarely practiced. The surgical procedures for LDLT are more technically challenging than those for cadaveric whole liver transplantation. LDLT requires a full understanding of hepatobiliary anatomy and continuous technical refinement of the procedure. The development of innovative techniques is a key factor for a successful LDLT. Some of the technical highlights include selective vascular occlusion techniques for donor hepatectomy, hepatic arterial reconstruction under the microscope, the introduction of intraoperative ultrasound, graft volume estimation, hepatic venous reconstruction using cryopreserved vascular grafts, and the use of the right lateral sector of the liver. These techniques have improved the success rate of LDLT over the past few years. This review focuses on the surgical techniques for LDLT on the basis of our experience with adult LDLT at the Tokyo University Hospital.

Intertemporal Trade between Developed and Developing Nations : A Model of Host-Donor Tensions

Enders, Walter,Roy, Raj 세종대학교 국제경제연구소 1991 Journal of Economic Integration Vol.6 No.2

Using a two-country overlapping generations model, we analyze some of the tensions between developed and developing nations regarding international capital movements. The nature of the model is such that optimizing agents in the South have a high rate of time preference. Otherwise, the North and the South are alike in all resepects. The differential rate of time preference means that the South is likely to have a relatively low capital/labor ration, wage rate, and level of per capita income but a relatively high interest rate in autarkic equilibrium. The introduction of international capital flows (intertemporal trade) will be welfare reducing for the current generation in the South even though it may increase the next generation's (and steady state) utility. We discuss the international conflicts which arise with international capital movements and the intergenerational conflicts which arise within each nation.

IV ECM Threshold Cointegration Tests and Nonlinear Monetary Policy in Korea

Walter Enders,Junsoo Lee,Mark C. Strazicich 한국개발연구원 2007 KDI Journal of Economic Policy (KDI JEP) Vol.29 No.2

The goal of this paper is to examine the validity of nonlinear Taylor rules in Korea. To perform our tests, we utilize new IV ECM threshold cointegration tests that are invariant to nuisance parameters. The new tests have a standard chi-square distribution and the same critical values can be used throughout. This is in contrast to OLS ECM threshold cointegration tests, which depend on nuisance parameters and have nonstandard distributions. After finding significant support for nonlinear cointegration, we find that the Bank of Korea raises the call rate of interest only when inflation is above a threshold rate. We additionally find that the Bank of Korea increases the call rate of interest to possibly counter domestic currency deprecation only when the rate of currency deprecation exceeds a threshold.

Articles : Intertemporal Trade between Developed and Developing Nations: A Model of Host-Donor Tensions

( Walter Enders ),( Raj Roy ) 세종대학교 경제통합연구소 1991 Journal of Economic Integration Vol.6 No.2

Using a two-country overlapping generations model, we analyze some of the tensions between developed and developing nations regarding international capital movements. The nature of the model is such that optimizing agents in the South have a high rate of time preference. Otherwise, the North and the South are alike in all resepects. The differential rate of time preference means that the South is likely to have a relatively low capital/labor ratio, wage rate, and level of per capita income but a relatively high interest rate in autarkic equilibrium. The introduction of international capital flows (intertemporal trade) will be welfare reducing for the current generation in the South even though it may increase the next generation`s (and steady state) utility. We discuss the international conflicts which arise with international capital movements and the intergenerational conflicts which arise within each nation.

Identification of Novel Regulators of B Cell Development and Function Using ENU Mutagenesis

Anselm Enders,Mehmet Yabas,Lisa A Miosge,Alanna Short,Yovina Sontani,Hannes Bergmann,Belinda Whilttle,Nadine Bartel,T. Daniel Andrews,Matthew A Field,Yafei Zhang,Edward M Bertram,Christopher C Goodnow 한국실험동물학회 2014 한국실험동물학회 학술발표대회 논문집 Vol.2014 No.8

GSTT1 is Deregulated in Left Colon Tumors

Coskunpinar, Ender,Canbay, Emel,Oltulu, Yasemin Musteri,Tiryakioglu, Necip Ozan,Bugra, Dursun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5

Our aim was to determine GSTT1 expression levels in left colon tumors and paired normal tissue in order to identify specific alterations in GSTT1 mRNA levels. Alterations in GSTT1 expression in twenty-four left-sided colon tumors and paired cancer free tissue were determined by qRT-PCR. Significant fold changes were determined with t-test. When compared with cancer free tissue, left colon cancers showed a significant decrease in GSTT1 expression. However, GSTT1 mRNA levels among different grades increased gradually in correlation with tumor grade. Our results suggest that downregulation of GSTT1 in left-sided colon cancers is an early event and is reversed with cancer progression, probably due to cellular defense mechanisms as a response to changes in the microenvironment.

Unilateral Posterior Surgery for Severe Osteoporotic Vertebrae Fractures’ Sequelae in Geriatric Population: Minimum 5-Year Results of 109 Patients

Tuna Pehlivanoglu,Yigit Erdag,Ismail Oltulu,Umut Dogu Akturk,Emre Korkmaz,Kerem Yildirim,Ender Sarioglu,Kerem Gun,Ender Ofluoglu,Mehmet Aydogan 대한척추신경외과학회 2021 Neurospine Vol.18 No.2

Objective: This study aimed to evaluate the efficacy and safety of modified posterior vertebral column resection (PVCR) combined with anterior column restoration in elderly patients presenting with thoracic or thoracolumbar osteoporotic fractures with spinal cord compression and severe pain. Methods: One hundred nine patients with one level thoracolumbar osteoporotic fracture and at least 5 years of follow-up were included. They underwent posterior instrumentation performed with polymethymetachrylate augmented pedicle screws. A modified PVCR (unilateral costotransversectomy+hemilaminectomy) combined with the insertion of an expandable titanium cage for anterior column restoration was undertaken. Patients were evaluated clinically and radiographically. Results: Patients had a mean age of 74.1 and a follow-up duration of 92.3 months. Mean duration of operations, hospital stays, and mean loss of blood were 172.3 minutes, 4.3 days, and 205.4 mL. All of the patients were mobilized immediately after surgery. The mean preoperative local kyphosis angle improved from 39.3° to 4.7° at the last follow-up (p=0.003). Patients preoperative mean visual analogue score, Japanese Orthopaedic Association, and Oswestry Disability Index scores improved from 7.7/8.6/76.3 to 1.6/26.1/17.4 (p<0.001 for all), respectively. The average 36-item Short-Form survey physical component summary/mental component summary scores at the last follow-up were 55.1/56.8. A dural tear was detected intraoperatively in 1 patient and repaired immediately. Conclusion: Subtotal PVCR combined with the insertion of an expandable titanium cage was detected as a safe and effective method for osteoporotic vertebrae fractures’ sequelae in the older population involving spinal cord compression by enabling the decompression of the spinal canal and reconstruction of the resected segment, resulting in significant improvement in clinical and radiographic outcomes.

Estimating the effect of abandoning coppice management on carbon sequestration by oak forests in Turkey with a modeling approach

Lee, Jongyeol,Makineci, Ender,Tolunay, Doğ,anay,Son, Yowhan Elsevier 2018 The Science of the total environment Vol.640 No.-

<P><B>Abstract</B></P> <P>A significant area of the oak forests in Turkey has been historically managed by short-rotation coppicing for wood production. Coppice management was almost abandoned in Turkey in 2006 and so investigating its impact on forest carbon (C) sequestration has become an important issue. Therefore, we investigated the net effect of this change in management on C sequestration by oak forests in Turkey using field measurement data and a forest C model (Forest Biomass and Dead organic matter Carbon (FBDC) model). The FBDC model estimated the annual forest C dynamics and considered the effect of the substitution of wood for fossil fuels under two management scenarios over a 100-year period: (1) abandoning coppice (no management) and (2) continuing coppice (20-year-interval harvest). The field measurement data were used to parameterize the FBDC model to the study sites and to verify the simulated C stocks. Continuing coppice management constrained an increase in the C stocks (116.0–140.3 Mg C ha<SUP>−1</SUP>) and showed a mean annual C sequestration of 0.6 Mg C ha<SUP>−1</SUP> yr<SUP>−1</SUP> if wood was substituted for fossil fuels. In contrast, abandoning coppicing practices increased the level of forest C stocks (128.1–236.2 Mg C ha<SUP>−1</SUP>), enhancing the mean annual C sequestration to 1.1 Mg C ha<SUP>−1</SUP> yr<SUP>−1</SUP>. Accordingly, the abandonment of coppice management increased the mean annual C sequestration by 0.5 Mg C ha<SUP>−1</SUP> yr<SUP>−1</SUP> in the long-term. However, sensitivity analysis showed a possibility of a larger difference in C sequestration between the two scenarios due to a decrease in the stand productivity by repeated coppices and a high likelihood of a lower substitution effect. The verification supported the scientific reliability of the simulation results. Our study can provide a scientific basis for enhancing C sequestration in coppice forests.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Abandoning coppice in Turkey is expected to affect carbon (C) sequestration. </LI> <LI> C sequestration was estimated under abandoning and continuing coppice scenarios. </LI> <LI> Forest carbon model and field measurement data were combined. </LI> <LI> Abandoning and continuing coppice sequestered 1.1 and 0.6 Mg C ha<SUP>−1</SUP> yr<SUP>−1</SUP>. </LI> <LI> The abandonment of coppice would enhance the C sequestration in the long-term. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>