Evaluation of the effect of two different occlusal splints on maximum occlusal force in patients with sleep bruxism : a pilot study

Duygu Karakis,Arife Dogan,Bulent Bek 대한치과보철학회 2014 The Journal of Advanced Prosthodontics Vol.6 No.2

PURPOSE. The occlusal splint has been used for many years as an effective treatment of sleep bruxism. Several methods have been used to evaluate efficiency of the occlusal splints. However, the effect of the occlusal splints on occlusal force has not been clarified sufficiently. The purpose of this study was to evaluate the effect of occlusal splints on maximum occlusal force in patients with sleep bruxism and compare two type of splints that are Bruxogard-soft splint and canine protected hard stabilization splint. MATERIALS AND METHODS. Twelve students with sleep bruxism were participated in the present study. All participants used two different occlusal splints during sleep for 6 weeks. Maximum occlusal force was measured with two miniature strain-gage transducers before, 3 and 6 weeks after insertion of occlusal splints. Clinical examination of temporomandibular disorders was performed for all individuals according to the Craniomandibular Index (CMI) before and 6 weeks after the insertion of splints. The changes in mean occlusal force before, 3 and 6 weeks after insertion of both splints were analysed with paired sample t-test. The Wilcoxon test was used for the comparison of the CMI values before and 6 weeks after the insertion of splints. RESULTS. Participants using stabilization splints showed no statistically significant changes in occlusal force before, 3, and 6 weeks after insertion of splint (P>.05) and participants using Bruxogard-soft splint had statistically significant decreased occlusal force 6 weeks after insertion of splint (P<.05). There was statistically significant improvement in the CMI value of the participants in both of the splint groups (P<.05). CONCLUSION. Participants who used Bruxogard-soft splint showed decreases in occlusal force 6 weeks after insertion of splint. The use of both splints led to a significant reduction in the clinical symptoms.

Tracheobronchial Angle Measurements in Children: An Anthropometric Retrospective Study With Multislice Computed Tomography

Duygu Herek,Ozkan Herek,Furkan Ufuk 대한이비인후과학회 2017 Clinical and Experimental Otorhinolaryngology Vol.10 No.2

Objectives. The purpose of this study is to investigate if any change exists in the values of tracheal bifurcation angles (subcarinal angle [SCA] and interbronchial angle [IBA]), right and left bronchial angles (RBA and LBA) in different pediatric age groups. Methods. Chest computed tomography (CT) images of children aged 18 years and younger were reviewed retrospectively by two radiologists who were blinded to each other’s measurements. One hundred and eighteen children were involved. RBA, LBA, SCA, and IBA were measured on coronal reformatted images. Subjects were classified into three groups according to their age. Measurement of IBA was done by measuring the angle between the lines drawn along the central axis of right and left main bronchi over their length. RBA and LBA were measured at the intersection points of the lines drawn along the inferior borders of the right and left main bronchi and the line passing through the longitudinal axis of trachea. Sums of RBA and LBA gave SCA. Interobserver agreement was also analyzed. Results. SCA, IBA, and RBA values were statistically significant between children of ages less than 10 years and over 10 years (P<0.01). Interobserver agreement was excellent with an intraclass correlation coefficient score of 0.87 (95% confidence interval) for RBA, SCA, and IBA measurements. Conclusion. We concluded that tracheal bifurcation angles are wider in children of age 10 years and younger. As age increases values of SCA, IBA, and RBA decrease.

Examination of Regular Participation at an Obesity Center with a Retrospective Evaluation of the Effects of Regular Participation on Patient Mental Status and Blood Parameters

Duygu İlke Yıldırım,Mehmet Ali Eryılmaz,Memduha Aydın 대한비만학회 2020 The Korean journal of obesity Vol.29 No.2

Background: Obesity is the main cause of type 2 diabetes, coronary artery disease, musculoskeletal disorders, some cancers, and mental disorders, and many other diseases leading to mortality. The aim of this study was to determine the effects of participation in an obesity center on patient mental status and blood parameters within 3 months and to show the relationship of this participation with depression, anxiety, and other parameters. Methods: This was a descriptive and cross-sectional study. Of 2,591 patients admitted to an obesity center between November 1, 2018 and November 1, 2019, 317 met the inclusion criteria. This study was a descriptive and cross-sectional study of the data from those 317 patients. Results: Of the patients enrolled in the study, 90.5% were female and 9.5% were male. Weight, occupation, body mass index, body fat percentage, waist circumference, hip circumference, glycosylated hemoglobin (HbA1c), Beck Depression Scale, and Beck Anxiety Scale were important determinants in our univariate analyses associated with the regular receipt of center education. HbA1c (odds ratio, 1.661; 95% confidence interval, 1.140–2.421; P=0.008) was shown to be multivariate predictors of amount of participation in center education. Conclusion: These results support that regular participation in obesity center education has a positive effect on patients mental status, blood parameters, and anthropometric measurements. Thus, increasing the number of obesity centers is of great importance in treating obesity and improving obese patient mental status.

Preparation of poly(2-ethyl aniline)/kaolinite composite materials and investigation of their properties

Duygu Anaklı,Sevil Çetinkaya 한국물리학회 2010 Current Applied Physics Vol.10 No.2

Conductive poly(2-ethyl aniline) (PEAn)/kaolinite composite was prepared by chemical polymerization in aqueous HCl medium in the presence of kaolinite particles by using potassium chromate (K2CrO4) as oxidant. Effects of polymerization conditions, such as concentrations of oxidant and 2-ethyl aniline, polymerization time and temperature on PEAn content and conductivity of composite, were investigated. The prepared composite material, having the highest PEAn content and conductivity, was obtained in the polymerization carried out at 20 ℃ for 2 h with 0.2 M K2CrO4 and 0.2 M EAn. It was observed that the micro-hardness of prepared composites increased with the increase in the PEAn contents of composites. The highest micro-hardness value of 7.92 kg mm-2 was reached at 24.6% PEAn content. Characterization of composites was carried out by FTIR spectroscopy, XRD, TGA and SEM techniques.

Protein substitutions as new-generation pharmanutrition approach to managing phenylketonuria

Duygu Ağagündüz,Fatma Nur Keskin,Teslime Özge Şahin,Raffaele Capasso 대한소아청소년과학회 2023 Clinical and Experimental Pediatrics (CEP) Vol.66 No.8

Phenylketonuria (PKU), an autosomal recessive inherited metabolic disorder, is caused by a mutation in the phenylalaninehydroxylase (PAH) gene on the 12th chromosome. DefectivePAH activity ultimately leads to increased phenylalanine (Phe)blood concentrations (hyperphenylalaninemia) that harm thebrain. The primary purpose of PKU treatment is to maintainthe blood Phe level to prevent certain undesired effects. Hence, lifelong medical nutrition therapy is recommendedfor these patients. The usefulness of natural protein sourcesmay be limited, as they are based on individual Phe tolerance,and a patient’s daily protein requirements are supported byPhe-free amino acid mixtures. A few PKU treatment centersrecently started using supplemental casein glycomacropeptide,pegvaliase, or large neutral amino acids, and some patients aretreated by responding to tetrahydrobiopterin, which works asa pharmaceutical chaperone (prescribed as sapropterin dihydrochloride). This review discusses the efficacy and safetyconsiderations of basic medical nutrition approaches and newgeneration protein substitutes that are used to treat PKU.

Free vibrations of fluid conveying microbeams under non-ideal boundary conditions

Duygu Atcı,Süleyman Murat Bağdatlı 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.24 No.2

In this study, vibration analysis of fluid conveying microbeams under non-ideal boundary conditions (BCs) is performed. The objective of the present paper is to describe the effects of non-ideal BCs on linear vibrations of fluid conveying microbeams. Non-ideal BCs are modeled as a linear combination of ideal clamped and ideal simply supported boundary conditions by using the weighting factor (<i>k</i>). Non-ideal clamped and non-ideal simply supported beams are both considered to show the effects of BCs. Equations of motion of the beam under the effect of moving fluid are obtained by using Hamilton principle. Method of multiple scales which is one of the perturbation techniques is applied to the governing linear equation of motion. Approximate solutions of the linear equation are obtained and the effects of system parameters and non-ideal BCs on natural frequencies are presented. Results indicate that, natural frequencies of fluid conveying microbeam changed significantly by varying the weighting factor <i>k</i>. This change is more remarkable for clamped microbeams rather than simply supported ones.

Microwave drying and moisture diffusivity of white mulberry: experimental and mathematical modeling

Duygu Evin 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.10

The literature surveyed revealed that drying kinetics of white mulberry under microwave treatment has not been investigated. In present study, both experimental study and mathematical modeling on microwave drying of white mulberry was performed. The microwave drying process which reduced the moisture content of mulberry from 3.76 to 0.25 (g water/g dry matter) was carried out at 90, 180, 360,600, and 800 W in a modified microwave drying set-up. The effects of microwave drying technique on the moisture ratio and drying rate of white mulberry were investigated experimentally. Both the effects of microwave power level (under the range of 90-800W) and initial sample weight (50-150g) were studied. No constant rate period was observed. Mathematical modeling of thin layer drying kinetics of white mulberry under microwave treatment was also investigated by fitting the experimental drying data to eight thin layer drying models. Among the models proposed, Midilli et al. model precisely represented the microwave drying behavior of white mulberry with the coefficient of determination higher than 0.999 and mean square of deviation (χ2) and root mean square error (RMSE) lower than 1.1x10-⁴ and 8.9x10-³, respectively for all the microwave drying conditions studied. The effective moisture diffusivity (D_eff ) of white mulberry varied from 0.45 x10_-8 to 3.25x10-8 m²s-¹. Both the drying constant (k) and D_eff increased with the increase of microwave power level.

Effects of Oxcarbazepine and Levetiracetam on Calcium, Ionized Calcium, and 25-OH Vitamin-D3 Levels in Patients with Epilepsy

Duygu Aksoy,Betül Tekin Güveli,Pelin Doğan Ak,Hüseyin Sarı,Dilek Ataklı,Baki Arpacı 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.1

Objective: The primary objective of the present study was to further elucidate the effects of oxcarbazepine (OXC) and levetiracetam (LEV) monotherapies on the bone health status of patients with epilepsy. Methods: This study included 48 patients who attended our epilepsy outpatient clinic, had a diagnosis of epilepsy, and were undergoing either OXC or LEV monotherapy and 42 healthy control subjects. The demographic and clinical features of the patients, including gender, age, onset of disease, daily drug dosage, and duration of disease, were noted. Additionally, the calcium, ionized calcium, and 25-OH vitamin-D3 levels of the participants were prospectively evaluated. Results: The 25-OH vitamin-D3, calcium, and ionized calcium levels of the patients taking OXC were significantly lower than those of the control group. These levels did not significantly differ between the patients taking LEV and the control group, but there was a significant negative relationship between daily drug dose and ionized calcium levels in the LEV patients. Conclusion: In the present study, anti-epileptic drugs altered the calcium, ionized calcium, and 25-OH vitamin-D3 levels of epilepsy patients and resulted in bone loss, abnormal mineralization, and fractures. These findings suggest that the calcium, ionized calcium, and 25-OH vitamin-D3 levels of patients with epilepsy should be regularly assessed.

Mass transfer enhancement factor for chemical absorption of carbon dioxide into sodium metaborate solution

Duygu Uysal Zıraman,Özkan Murat Doğan,Bekir Zühtü Uysal 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.9

Hydrogen is getting increasing attention as a medium for energy storage, and sodium borohydride is accepted as a suitable carrier for hydrogen. The main product of the process by means of which hydrogen is produced from sodium borohydride is sodium metaborate. Our aim was to find an alternative use for sodium metaborate and specifically investigating the feasibility to use it for carbon dioxide capture from flue gases. The products of this chemical absorption are sodium carbonate, sodium bicarbonate and boric acid, all of which are industrially important chemicals. A bubble column was used in the experiments. Oxygen desorption technique was employed to determine the liquid side physical mass transfer coefficient. Chemical mass transfer coefficient was determined by absorption of carbon dioxide from its mixture with nitrogen into sodium metaborate solution. Enhancement factor was then calculated and a correlation was developed for it.

Transcriptomic analysis of the heat stress response for a commercial baker’s yeast Saccharomyces cerevisiae

Duygu Varol,Vilda Purutçuoğlu,Remziye Yılmaz 한국유전학회 2018 Genes & Genomics Vol.40 No.2

The aim of this study is to explore the effects of heat stresses on global gene expression profiles and to identify the candidate genes for the heat stress response in commercial baker’s yeast (Saccharomyces cerevisiae) by using microarray technology and comparative statistical data analyses. The data from all hybridizations and array normalization were analyzed using the GeneSpringGX 12.1 (Agilent) and the R 2.15.2 program language. In the analysis, all required statistical methods were performed comparatively. For the normalization step, among alternatives, the RMA (Robust Microarray Analysis) results were used. To determine differentially expressed genes under heat stress treatments, the fold-change and the hypothesis testing approaches were executed under various cut-off values via different multiple testing procedures then the up/down regulated probes were functionally categorized via the PAMSAM clustering. The results of the analysis concluded that the transcriptome changes under the heat shock. Moreover, the temperature-shift stress treatments show that the number of differentially up-regulated genes among the heat shock proteins and transcription factors changed significantly. Finally, the change in temperature is one of the important environmental conditions affecting propagation and industrial application of baker’s yeast. This study statistically analyzes this affect via one-channel microarray data.