전시-P-91 : Costs and Productivities of Forest Biomass Harvesting Operations in the US

( Han Sup Han1 ),( Sang Kyun Han ),( Du Song Cha ),( Nam Hun Kim ) 韓國木材工學會 2013 한국목재공학회 학술발표논문집 Vol.2013 No.-

상악 골절단 및 급속구개확장(SARME)을 이용한 술전 치성보상의 해소와 악교정 치험 2례 : REPORT OF 2 CASES

강상원,김명래,김기환,김한석,김채두 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

This is to review the surgically assisted rapid maxillary expansion followed by orthodontic treatment for malocclusion with maxillary narrow-arch. Two patients who presented with narrow-arch maloccluson and transverse maxillary deficiency underwent a Lefort I osteotomy extending to the zygomatico-maxillary but-trees and splitting of the midpalates. Orthopedic expansion was initiated with one complete rotation 0.8㎜ of the expansion screw on the day, and followed by two quarter-turn 0.4㎜ each day thereafter untill the arch expanded to preplanned level. Changes of the mid-incisal gap space. intermolar width. incisal inclination, TMJ symptoms and reapse tendency were examined periodically. After the surgico-orthodontic leveling and alignment. pre-planned orthognathic surgeries (maxillary & mandibular osteotomies) were rendered to correct the maxillofacial deformites. Results:Intermolar width (IMW) was increased to 13㎜ within 20 days and the gap between to cen-tral incisors was declined to5-7^。. There were neither complaints nor signs of TMJ disorders during treatment. The amount of relapse was less than 0.5㎜ in a year. Therefore, the surgically assisted rapid palatal expansion(SARME) can be a pre-orthodontic option to gain the interdental space in narrow-arch malocclusion with crowding and to reduce the labial inclination of upper incisors without extraction of premolars.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

Enalapril 에 의한 기침 발생율

노승익(Seung Ik Roh),김명선(Myeong Seon Kim),김은실(Eun Sil Kim),서두선(Du Seon Seo),정내인(Nae In Jeong),이명숙(Myeong Suk Lee),한승수(Seung Soo Han),김광희(Kwang Hoi Kim),김윤권(Yoon Kweon Kim) 대한내과학회 1994 대한내과학회지 Vol.47 No.1

N/A Background: Enalapril is an angiotensin-converting enzyme inhibitor that has been widely used in treating hypertension, congestive heart failure, DM and various renal diseases. Cough has been recognized as a side effect of angiotensin-converting enzyme inhibitors. Therefore we studied the incidence and the chracteritics of Enalapril induced cough in Korea. Method: The sixty eight patients with Enalapril who visited out-patients department of internal medicine, Han-Il General Hospital during the period from april 1992 to october 1992 were included in this study. In all patients careful history taking and review of chart was done. Patients with respiratory disease were excluded. The criteria of angiotensin converting enzyme inhibitor induced cough was that cough developed after administration of Enalapril and improved after discontinuing drug and readministration of drug induce resume of symptom. Resnlts: Subjects include 34 males, 34 females and their average age was 53.3 years, Diseases of theirs were hypertension (57 cases}, congestive heart failure (5 eases), various renal disease (28 cases) and 9 patients of them were smokers. Average drug dosage was 11.7 mg a day and average administration duration was 182 days. Of the 68 patients, 23 patients (33.8%) had chronic cough due to enalapril, which had 12 male and 11 female patients. The cough disappearing time after withdrawal of the angiotensin-converting enzyme inhibitors was average 7.8 days. In 16 patients (two thirds of them), cough disappeared within 4 days after drug withdrawal. 9 patients had to stop taking drug because of severe cough. Generally the characters of cough induced by angiotensin-converting enzyme inhibitors were dry, persistent, tickling and tended to develope especially at night, Conclusion: Cough is not uncommon side effect in angiotensin-converting enzyme inhibitor users. There fore clinician should consider angiotensin-converting enzyme inhibitor induced cough initially when cough developed after angiotensin-converting enzyme inhibitor administration.

Carbofuran의 독성과 Phenobarbital Sodium의 독성경감효과

김진선,한두석 원광대학교 생체재료·매식연구소 1997 원광생체재료·매식 Vol.6 No.2

This study was carried out to investigate the toxicity of insecticide carbofuran that is scattered to farm products which were essential for human diet, and the antitoxic effects of phenobarbital sodium (PB) on carbofuran in vivo and in vitro. For In vivo study, Sprague Dawley male rats were used as experimental animals and divided into carbofuran only administered group and simultaneous application group of carbofuran and PB, At 30 min and 1, 3, 6, 12, 24, 48 and 96 hr interval after each treatment, the animals were sacrificed by decapitation and brain were immediately removed, immersed in fixatives, and processed with routine metho-d for light microscopic study. Paraffin sections were stained with hematoxylin & eosin and cresyl echt violet. For In vitro experiment, The experimental groups divided into six groups; control group was cultured in media only, carbofuran MTT_50 or SRB_50 groups were cultured in the media containing carbofuran MTT_50 or SRB_50 and four experimental groups were cultured in the media containing carbofuran SRB_50 plus various concentrations of PB. The 5.0 × 10 exp (4) cells/ml of rat nerve cells in each well of 24 multidish were cultured. After 24 hours, the cells were treated with solution of all groups. After the nerve cells of all groups were cultured in the same condition for 48 hours, 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) and sulforhodamine B protein (SRB) of the colorimetric assay were measured to evaluate the cyotoxicity of cell organelles. The light microscopic study was carried out to observe morphological changes of cultured rat nerve cells. The results were as follows; 1. Cerebral cortex showed severe congestion at 6 hr administration, and degeneration of pyramidal cells and granular cells at 12 hr after carbofuran only. 2. Pyramidal cells and granular cells of cerebral cortex showed regeneration at 24 hr in combination treatment of carbofuran and PB. 3. The concentration of Carbonfuran MTT50 and SRB50 were 78 μM and 87 μM, respectively. 4. MTT and SRB quantity were show significantly increased in carbofuran-PB 100 μM treatment group of MTT assay and carbofuran-PB 100μM treatment group of SRB assay, respectively. 5. Nerve cells became clear by regeneration in carbofuran-PB 50μM treatment group. These results suggest that phenobarbital sodium might modulate the toxicity induced by carbofuran. The result suggest that phenobarbital sodium might modulate the toxicity induced by carbofuran.

삼출성 늑막액에서 양악성 감별지표로서 CEA, TPA, SCC Ag 측정의 의의

김경찬,김민수,김미정,권두영,한승범,전영준 啓明大學校 醫科大學 1998 계명의대학술지 Vol.17 No.4

상피 세포에서 기원한 대표적인 종양표지자인 carcinoembryonic antigen (이하 CEA로 약함)은 삼출성 늑막액 환자의 양악성 감별에 보고적으로 사용되고 있다. CEA 이외에 혈청에서 양악성감별의 보조적 지표로 알려진 tissue polypeptide antigen (이하 TPA로 약함)과 squamous cell carcinoma antigen (이하 SCC Ag으로 약함)을 혈청과 늑막에서 동시 측정하여 늑막삼출액의 악성 감별에 어느 정도의 임상적인 유용성이 있는지를 알아보기 위하여 이 연구를 시행하였다. 1997년 1월 1일부터 동년 8월 31일까지 계명대학교 동산의료원에 입원한 환자들 중 삼출성늑막액을 가진 61명을 대상으로 하여 혈청과 늑막액에서 CEA, TPA, SCC Ag의 수치를 방사면역법으로 측정하였다. 각각의 조양표지자들은 악성과 양성군으로 구분한 뒤 분석하였으며 악성군이 28례, 양성군이 33례이었다. 그리고 진단양성기준치를 설정한 뒤 종양표지자들의 특이도, 민감도를 산출하였고 상기 지표들을 종양표지자와 늑막액 세포검사르 조합한 경우에도 산출하여 비교 분석하였다. 혈청 CEA 와 TPA는 각각 7.0 ng/ml, 80.0 ng/ml, 늑막액 CEA와 TPA는 각각 50. ng/ml, 4700.0 ng/ml로 진단양성기준치를 설정하였을 때 특이도를 낮추지 않으면서 가장 높은 민감도를 보였다. 늑막액 세포검사와 동시에 혈청 TPA 도는 늑막액 CEA를 측정하였을 때 특이도는 떨어뜨리지 않으면서 민감도를 높이는 좋은 조합인 것으로 나타났으며 혈청 CEA 및 TPA수치를 늑막액 세포검사와 도시에 시행하였을 때 특이도를 떨어뜨리지 않으면서 가장 높은 민감도를 얻었다. 늑막액 세포검사가 음성인 경우에도 혈청 CEA와 TPA를 동시에 측정하여 높은 민감도와 특이도를 얻을 수 있었다. 따라서 CEA와 TPA는 늑막삼출액의 양악성 감별 진단 유용한 보조적 지표로서 사용할 수 있을 것으로 판단된다. Carcinoembryonic antigen(CEA), the most widely used tumor marker was measured in pleural fluid of patients with exudative pleural effusions in order to differentiate malignant from benign effusions. This study was performed to find out if there is any clinical utility in differential diagnosis of malignancy by measuring simultaneously CEA, tissue polypeptide antigen(TPA) and squamous cell carcinoma antigen(SCC Ag) in serum and pleural fluid. The study population was 61 patients with exudative pleural effusions who were admitted to Keimyung University Hospital from January 1 to August 31, 1997. Each CEA, TPA and SCC Ag level in serum and pleural fluid were measured using radioimmunoassay method. These patients were divided to malignant and benign group. Malignant group consists of 28 cases and benign group consists of 33 cases. And the sensitivity and specificity of each tumor marker was obtained using cut-off value and that combining tumor markers and pleural fluid cytology were also obtained and analyzed. When the cut-off value was applied to CEA and TPA in serum using 7.0 ng/ml and 80.0 ng/ml respectively, the highest sensitivity was obtained without specificity being lowered. The same result was obtained when the cut-off value was applied to CEA and TPA in pleural fluid using 5.0 ng/ml and 4700.0 ng/ml respectively. When CEA in pleural fluid or TPA in serum were measured in combining with pleural fluid cytology sensitivity was increased without decreasing specificity than measured in pleural fluid cytology alone. When CEA in serum and TPA in serum were measured in combining with pleural fluid cytology simultaneously, the highest sensitivity was produced without decreasing specificity than measured in any other combinations. In addition, when serum CEA and TPA in serum were measured in the negative group of pleural fluid cytology, high sensitivity and specificity were obtained. These data suggest that CEA and TPA can be used as useful tumor markers for the differential diagnosis of malignancy and benign condition in patients with exudative pleural effusions.

김치가 노화촉진쥐 뇌의 유리기 생성 및 항산화효소 활성에 미치는 영향

김종현,류재두,이한기,박정희,문갑순,최홍식,송영옥 부산대학교 김치연구소 2002 김치의 과학과 기술 Vol.8 No.-

본 연구는 김치가 노화와 직접적인 관련이 있는 유리기 생성 및 항산화 효소활성에 미치는 영향을 살펴보기 위하여 배추김치, 배추갓김치 그리고 갓김치를 식이중량의 5% 첨가하여 실험식이를 제조하여 이를 노화촉진쥐인 SAMP8에게 1년간 섭취시켰다. 총유리기, OH radical, H_2O_2농도 그리고 TBARS 농도 모두 가령에 따라 증가하였으며, 김치섭취시 유의적으로 감소되었다(p<0.05), 김치군에 있어서 생성된 유리기를 제거하기 위해 항산화계 효소인 SOD, catalase, GSH-px 그리고 GSH/GSSG는 모든 김치군에서 유의적으로 증가 하였다(P<0.05). 따라서 김치섭취는 먼저 가령에 의해 생성되는 유리기의 생성은 억제시키면서, 둘째 이를 제거하기 위한 항산화계 효소 활성은 더욱 활성화시키므로써 항노화 기능을 발휘한다고 생각된다. 김치종류 중에서는 배추갓김치와 갓김치가 배추김치보다 유리기 생성을 억제하고, 항산화계 활성을 증진시킨 것으로 보아 이들의 항노화 효과가 클것으로 생각된다. This study was performed to investigate the effect of kimchi intake on antiaging characteristics in the brain of senescence-accelerated mouse (SAM) in terms of free radical production and anti-oxidative enzymes. Two hundreds twenty SAM (20 mice) were divided into four groups and fed kimchi diet for 12 months. Experimental groups were kimchi free AIN-76 diet (control) group, Korean cabbage kimchi diet (KCK)group, 30% mustard leaf added Korean cabbage kimchi diet (MKCK) group, and mustard leaf kimchi diet (MLK) group. Concentrations of total free radical, OH radical and H_2O_2 of control group increased up to 123%, 262% and 174% of initial value (p<0.05) after one year. Increase in free radical production in kimchi groups due to aging was decreased by kimchi feeding. Among kimchi groups. MKCK and MLK groups showed greater inhibiting effect against free radical production than KCK. The concentration of TBARS in the bruin of control group also significantly increased up to 362% of initial value as aged (p<0.05) and production of TBARS in kimchi groups were decreased. When the activities of Cu, Zn-SOD, Mn-SOD, GSH-px and catalase of kimchi groups were compared to those of control at the same experimental period, anti-oxidative enzyme activities of kimchi groups were lower than those of control (p<0.05). But GSH/GSSG in kimchi groups were higher compared to control. In conclusion, decrease in free radical production and increase in anti-oxidative enzyme activities were observed from kimchi groups suggesting that kimchi might have important role on retarding aging. Among kimchi variety tested in this experiment, MKCK and MLK seem to have greater effect on inhibiting free radical production and increasing anti-oxidative enzyme activities than KCK.

금은화 추출물의 세포독성에 관한 연구

한종현,백승화,김일광,한두석 圓光大學校 韓醫學硏究所 1993 원광한의학 Vol.3 No.1

In order to investigate the cytotoxicity of Lonicerae Flos extract, their extracts were dissolved in distilled water and methanol. All material diluted from 10^-3to 10^-7(㎎/㎖) with distilled water putted in each well of 24 multidish cultured rat fibroblast for 48hours. The cell number was calculated at 2 days and cell shape takes photographed by inverted microscope at same day. The results were as follows: 1. The rate of cell multiplication was the lowest in water extract from 10^-3 to 10^-7(㎎/㎖) concentration and the highest in ether and hexane extract at 10^-7(㎎/㎖) concentration. 2. Index of cytotoxicity was the highest with 3 score in water extract at 10^-3(㎎/㎖) concentration and the lowest with 1 score in ether, ethyl acetate or hexane extract at same concentration. 3. The degeneration of cell shape and number was the severest in water extract of 10&-4(㎎/㎖) concentration, but ether and hexane extracts in same concentration were weaker than water extract. These results indicate that the cytotoxicity of extracts by ether and hexane from same Lonicerae Flos was weaker then water extract.

大學 男女 球技選手들의 最大無機的 Power

김태운,유재충,안덕균,선우섭,이한,손두욱,박충서 慶熙大學校 社會體育硏究所 1994 體育科學論叢 Vol.- No.7

The purpose of the present research is to compare characteristics of maximal anaerobic power observed in different types of sports and player's sex differences. We have reached the following conclusions from the results we obtained by measuring maximal anaerobic power and blood lactate concentration of 60 elite university male and female players during the exercise of bicycle ergometer: 1. As to absolute and relative values of maximal anaerobic power, male players are higher in the order of rugby and handball, whereas female players are higher in the order of hockey and soccer, but no significant differences are observed between types of sports. 2. Male players are noticably higher in absolute values of maximal anaerobic power(p<0.001), but relative value is very simi1ar to that of female players. 3. It is estimated that the fact, that female players show obvious higher mean anaerobic power(p<0.001) during the 3,4KP excercise is due to sex differences in ocdurrence work load of maximal anaerobic power. 4. Comparison of blood lactate concentration at each work load in different types of sports and player's sex differences show an increase in proportion to mean anaerobic power. The results given above clearly show the differences between the type of sports such as rugby and hockey requiring power and speed, and the type of sports such as handball and soccer requiring edurance.

소엽의 chloroform분획이 인체 구강유상피암종세포에 미치는 항암효과

김영일,한두석 원광대학교 생체재료·매식연구소 1997 원광생체재료·매식 Vol.6 No.2