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Doo‑Won Kim,Dae Ho Kim,Sung Ryong Kim,Bo‑Hye Kim,Yun Hyuk Bang,Duck Joo Yang,Go Bong Choi,Yoong Ahm Kim,Kap Seung Yang 한국탄소학회 2019 Carbon Letters Vol.29 No.5
This study demonstrates that low processing rate for producing polyacrylonitrile (PAN)-based carbon fiber is a critical to obtain a homogeneous radial microstructure with high resistance to oxidation, thereby resulting in their improved mechanical strength. The dry-jet wet spun PAN organic fibers were processed (e.g., stabilized and then carbonized) utilizing two different rates; one is 1.6 times longer than the other. The effect of processing rate on the microstructural evolutions of carbon fibers was analyzed by scanning electron microscopy after slow etching in air, as well as Raman mapping after graphitization. The rapidly processed fiber exhibited the multilayered radial structure, which is caused by the radial direction stretching of the extrusion in the spinning. In case of the slowly processed fiber, the layered radial structure formed in the spinning process was changed into a more homogeneous radial microstructure. The slowly processed fibers showed higher oxidation resistance, higher mechanical properties, and higher crystallinity than the rapidly processed one. Raman mapping confirmed that the microstructure developed during spinning was sustained even though fiber was thermally treated up to 2800 °C.
HPLC-ICP/MS 와 ICP/MS를 이용한 FAPAS 07187 쌀의 총비소, 무기비소, 카드뮴 측정
노현명 ( Hyun Myung Noh ),김지영 ( Ji Young Kim ),김원일 ( Won Il Kim ),( Anitha Kunhikrishnan ),김민지 ( Min Ji Kim12 ),김경진 ( Gyeong Jin Kim ),박기문 ( Ki Moon Park ),류지혁 ( Ji Hyock Yoo ),김두호 ( Doo Ho Kim ),이영자 ( Y 한국환경농학회 2013 한국환경농학회 학술대회집 Vol.2013 No.-
Metal (loid)s such as environmental contaminants affect food safety. Metal (loid)s exist trace extremely in agriculture products. Therefore it is important to analyze accurately about trace these metals. High resolution techniques and quality controls are needed to analyze these materials. In order to achieve quality results, standardized methods and techniques are required. So ISO(International Organization for Standardization) of laboratory proficiency testing is determination of laboratory testing performance by means of inter-laboratory comparison. The values have been derived as a consensus of a number of laboratories using a variety of methods. Proficiency tests were applied to analyze the metal(loid)s [inorganic arsenic (As), total As and cadmium (Cd)] in powdered rice FAPAS 07187 (Food Analysis Performance Assessment Scheme; February-April 2013). The rice powder sample was extracted with 1% HNO3 for inorganic As for microwave-assisted extraction using water at 95℃ for 90 min and their analysis by HPLC/ICPMS. Also, HNO3 for total As and Cd using microwave-assisted extraction using at 200℃ for 50 mins and analysis by ICP/MS. Validation check was performed for accuracy using CRM (NMIJ CRM 7503-a) for inorganic As, and CRM (IRMM-Rice CRM) for total arsenic and cadmium. The result were satisfactory. FAPAS 07187 the z-scores of inorganic As, total As and Cd in powdered rice were-1.8,-0.9 and 0.2(lzl<2, respectively).
( Won-Chul Doo ),( Dong-Yong Kim ),( Soo-Chang Kang ),( Kyung-Woo Yi ) 대한금속재료학회 ( 구 대한금속학회 ) 2007 METALS AND MATERIALS International Vol.13 No.3
Internal morphologies of bulk shape oxides in a melt of Ti bearing low-carbon steel were analyzed. The outer shapes of nearly spherical inclusions containing Ti were quite different from the shape of alumina inclusions that typically have a cluster form. A cross-section investigation using a polishing method and the FIB method revealed that the TiOx-Al2O3 complex oxide covers alumina clusters and that the interfaces of the alumina and complex oxide are modified as time passes.
Treatment with phosphodiester CpG-ODN ameliorates atopic dermatitis by enhancing TGF-β signaling
( Won-kook Ham ),( Eun-jung Lee ),( Myung Shin Jeon ),( Hae-young Kim ),( Gaurav Agrahari ),( Eun-joo An ),( Chul Hwan Bang ),( Doo-sik Kim ),( Tae-yoon Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2021 BMB Reports Vol.54 No.2
Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG phosphorothioate (PS CpG-ODN) are known to decrease IgE synthesis in Th2 allergy responses. Nonetheless, the therapeutic role of PS CpG-ODN is limited due to cytotoxicity. Therefore, we developed a phosphodiester (PO) form of CpG-ODN (46O) with reduced toxicity but effective against allergies. In this study, we first compared the toxicity of 46O with CpG-ODNs containing a PS backbone (1826S). We also investigated the therapeutic efficacy and mechanism of 46O injected intravenously in a mouse model of ovalbumin (OVA)- induced atopic dermatitis (AD). To elucidate the mechanism of 46O underlying the inhibition of IgE production, IgE- and TGF-β-associated molecules were evaluated in CD40/IL-4- or LPS/IL-4-stimulated B cells. Our data showed that the treatment with 46O was associated with a lower hematological toxicity compared with 1826S. In addition, injection with 46O reduced erythema, epidermal thickness, and suppressed IgE and IL-4 synthesis in mice with OVA-induced AD. Additionally, 46O induced TGF-β production in LPS/IL-4-stimulated B cells via inhibition of Smad7, which suppressed IgE synthesis via interaction between Id2 and E2A. These findings suggest that enhanced TGF-β signaling is an effective treatment for IgE-mediated allergic conditions, and 46O may be safe and effective for treating allergic diseases such as AD and asthma. [BMB Reports 2021; 54(2): 142-147]
A New Garden Pea Cultivar "Daehyup 2" with Large Seed Size and High Sugar Contents
Won Young Han,In Youl Baek,Sang Ouk Shin,Hyun Tae Kim,Jong Min Ko,Nam Suk Kang,Ki Won Oh,Chan Sik Jung,Doo Chull Shin,Sung Taek Kang,Myung Gun Chung,Keum Yong Park,Duck Yong Suh 한국육종학회 2007 한국육종학회지 Vol.39 No.3
A new garden pea cultivar, Daehyup 2, was developed at the Yeongnam Agricultural Research Institute (YARI) in 2006. It was selected from the cross between Olwandu and Sachulwandu in 1996. The preliminary, advanced, and regional yield trials for evaluation and selection of this cultivar were carried out from 2003 to 2006. It has white flower, yellow cotyledon, absent or very weakly curved pod shape and yellow seed color. It was resistant to virus and powdery mildew disease. The 100 green seed weight of Daehyup 2 was 65.5 g, which was 8.9 g heavier than check cultivar. The sucrose and total sugar contents of fresh pod of Daehyup 2 were 11.1% and 12.5%, respectively, which were 3.2% and 4.3% higher than those of Sachulwandu. The fresh pod yield of Daehyup 2 was similar to that of Sachulwandu with 12.16 ton per hectare in the regional yield trials carried out in three locations of Korea from 2005 to 2006.
Is the Serum Uric Acid Level Independently Associated with Incidental Urolithiasis?
( Doo-ho Lim ),( Min-ho Kim ),( Seokchan Hong ),( Yong-gil Kim ),( Chang-keun Lee ),( Seung Won Choi ),( Bin Yoo ),( Ji Seon Oh ) 대한류마티스학회 2018 대한류마티스학회지 Vol.25 No.2
Objective. Urolithiasis is one of the manifestations of gout and the risk is higher in gouty patients. On the other hand, an independent association between the urinary stone and serum uric acid (UA) level has not been established. This study examined whether the risk of urolithiasis increases with increasing serum UA level. Methods. Among the people who visited a tertiary hospital from 2010 to 2013, 13,964 individuals who underwent both ultrasonography and a laboratory test were recruited in the study. The risk of urolithiasis on ultrasonography was analyzed in association with the serum UA level by multiple logistic regression analysis with an adjustment for age, sex, body mass index, estimated glomerular filtration rate, and known underlying diseases, including diabetes mellitus and hypertension. Results. Among the 6,743 men (48.3%) and 7,221 women (51.7%), the age was 51.3±13.5 and the serum UA level was 4.5±2.1 mg/dL. Hyperuricemia (>7 mg/dL) was observed in 1,381 cases (9.9%). Urolithiasis was detected by ultrasonography in 608 cases (4.4%). The detection rates of urolithiasis in individuals with hyperuricemia and normouricemia were 5.9% and 4.1%, respectively (p=0.001). Multiple logistic regression analysis showed that individuals with hyperuricemia had a significantly higher risk of urolithiasis (adjusted odds ratio [OR]=1.54; 95% confidence interval [CI], 1.20∼1.96; p=0.001). A comparison of the highest with the lowest quartile of serum UA revealed a multivariable- adjusted OR of 3.17 (95% CI, 1.98∼5.11) for men and 1.79 (1.08∼2.93) for women. Conclusion. These results suggest that individuals with a higher serum UA level have a higher risk of subclinical and clinical urolithiasis. (J Rheum Dis 2018;25:116-121)
Evaluation of circulating IGF-I and IGFBP-3 as biomarkers for tumors in dogs
Doo-Won Song,노웅빈,서정향,Byung-Joon Seung,강현민,Jong-Won Kim,See-Hyoung Park,Hee-Myung Park 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.6
Background: Serum-based parameters are considered non-invasive biomarkers for cancer detection. In human studies, insulin-like growth factor-I and II (IGF-I and IGF-II) and insulin-like growth factor binding protein-3 (IGFBP-3) are useful as diagnostic or prognostic markers and potential therapeutic targets. Objectives: This study examined the diagnostic utility of circulating IGF-I, IGF-II, and IGFBP-3 levels in healthy dogs and dogs with tumors. Methods: The serum concentrations of these biomarkers in 86 dogs with tumors were compared with those in 30 healthy dogs using an enzyme-linked immunosorbent assay (ELISA). Results: The ELISA results showed no difference between healthy dogs and dogs with tumors in the serum IGF-II concentrations. On the other hand, there was a significant difference in the circulating IGF-I and IGFBP-3 levels between healthy dogs and dogs with tumors. The concentrations of serum IGF-I (median [interquartile range], 103.4 [59.5–175] ng/mL) in dogs with epithelial tumors were higher than those (58.4 ng/mL [43.5–79.9]) in healthy dogs. Thus, the concentrations of serum IGFBP-3 (43.4 ng/mL [33.2–57.2]) in dogs with malignant mesenchymal tumors were lower than those (60.8 ng/mL [47.6–70.5]) in healthy dogs. Conclusions: The serum IGF-I and IGFBP-3 levels can be used as diagnostic biomarkers in dogs with tumors.
Physicochemical characteristics and antioxidant potential of paprika (Capsicum annuum L.) wine
Kim, Chan Yong,Kwon, Oh Hun,Gun, Won Jong,Park, Yong-Sung,Dhungana, Sanjeev Kumar,Kim, Il-Doo Korean Society of Food Science and Technology 2019 한국식품과학회지 Vol.51 No.6
Paprika (Capsicum annuum L.) contains various phytochemicals, including carotenoids, ascorbic acid, tocopherol, flavonoids, and phenolic compounds, as well as natural food colorants. Very little information is available regarding wine produced from different colored paprikas. The objectives of this study were to prepare wines from red, orange, and yellow paprika and evaluate their physicochemical characteristics. The alcohol concentration, pH, titratable acidity, and reducing sugar content were not significantly affected by the type of paprika. Hunter's color values varied with the color of paprika. The total mineral content and 2,2-diphenyl-1-picrylhydrazyl radical scavenging potential of red paprika wine were significantly higher; however, the total polyphenol content of yellow paprika wine was significantly higher than that of the other wine samples. This study suggested that paprika could be used to prepare wine and red paprika might be appropriate for producing good-quality wine.
Doo Chull Shin,In Youl Baek,Won Young Han,Myoung Gun Choung,Sea Kwan Oh,Sung Taeg Kang,Su Dong Kim,Soon Chul Kim 한국육종학회 2003 한국육종학회지 Vol.35 No.4
A new sprouting soybean variety, 'achaekong'was developed at the National Yeongnam Agricultural Experiment Station (NYAES) in 2002. It was selected from the cross Hannamkong/Eunhakong. The preliminary, advanced, and regional yield trials for evaluation an
Kim, Hyung Wook,Kang, Dae Hwan,Choi, Cheol Woong,Park, Jong Hwan,Lee, Jin Ho,Kim, Min Dae,Kim, Il Doo,Yoon, Ki Tae,Cho, Mong,Jeon, Ung Bae,Kim, Suk,Kim, Chang Won,Lee, Jun Woo WJG Press 2010 WORLD JOURNAL OF GASTROENTEROLOGY Vol.16 No.34
<P>To investigate the effectiveness and safety of limited endoscopic sphincterotomy (EST) plus large balloon dilation (LBD) for removing choledocholithiasis in patients with periampullary diverticula (PAD).</P>