동씨침을 시술한 안면경련의 치험 3례

김태우,김효은,조명제,강영화,이재동,Kim, Tae-woo,Kim, Hyo-eun,Cho, Myung-je,Kang, Young-hwa,Lee, Jae-dong 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement of one side of face, In this study, the effect of Dong-Si acupuncture therapy for three patients with hemifacial spasm were evaluated. Methods : We have treated them with acupuncture treatment of Dong-Si acupuncture points(Cheuk-Samni and Cheuk-ha-Samni) and evaluated the effect by Scott's scale, For the first two weeks, it was dine once a day, and after two weeks, the other day. Results : Before therapy, the grades of spasm intensity classified by Scott's description in three cases were 3. And after Dong-Si acupuncture therapy, the grade of one case was 0, and two cases were 1. Conclusion : The Dong-Si acupuncture therapy for hemifacial spasm was effective and will be attempted to the patients with it.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

관상동맥내 스텐트 삽입후 발생한 관상동맥류 2례

제인수,허민영,문치숙,이재호,정수룡,조길현,이영민,김대경,김두일,김동수 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Coronary artery aneurysms are detected with increasing frequency because of the routine use of coronary angiography in the diagnosis and management of coronary artery disease. Although some coronary artery aneurysms are congenital or inflammatory, most are atherosclerotic. The prognosis of atherosclerotic coronary artery aneurysm may depend on the morphology of the aneurysm or the presence of coexisting obstructive disease. Coronary artery aneurysms have been also reported to occur after ballon angioplasty, directional athrectomy, laser angioplasty, and stent implantation with a frequency of 2% to 4%. The long-term outcome of post-intervention coronary artery aneurysm is unknown. We report two cases of the development of a coronary aneurysm 6 months after stent implantation as a treatment of severe obsructive coronary artery disease.

Acetobactor xylinum endo-β-1,4-glucanase CMCax의 결정학적 연구

김동섭, 김준식, 정용제 忠北大學校部設基礎科學硏究所 2007 自然科學硏究 Vol.21 No.-

-본문참고-

심미 브라켓의 종류와 브라켓-호선 각도에 따른 마찰 저항에 대한 연구

제영지,장민희,임용규,이동렬 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.5

본 실험은 마찰력을 줄이고 물리적 성질을 개선하여 최근에 개발된 수 종의 심미 브라켓들과 교정 탄선간에 발생하는 마찰력의 크기를 측정, 비교해 보고자 하였다. 일반 슬롯의 세라믹 브라켓인 Inspire, Signature III와 Cristaline V, 스테인레스 스틸 (SS) 슬롯을 가진 세라믹 브라켓인 Clarity, 골드 슬롯을 가진 Luxi II, Polyoxymethylene 계열의 플라스틱 브라켓인 Brillant, SS 슬롯을 가진 컴파짓 브라켓인 Spirit MB, 금속 브라켓인 Integra를 사용하여 018″ 원형의 교정 탄선에 0˚, 4˚, 8˚의 tip angulation을 부여하고 elastic module로 결찰한 뒤 인공 타액 상태에서 활주이동할 때의 운동 마찰력을 측정하였다. 연구 결과 슬롯에 silica 처리된 세라믹 브라켓 (CR)이 유의하게 낮은 마찰력을 보였고 (P < 0.05), 단결정 세라믹 브라켓이 (IN) 유의하게 큰 마찰력을 보였다 (P < 0.05). 플라스틱 브라켓인 polyoxymethylene계열의 BR이 낮은 마찰력 양상을 보였고 이는 금속 브라켓과 유사하였다. 모든 브라켓에서 브라켓-탄선 각도가 증가함에 따라 유의하게 마찰력이 증가하였으나 주사전자현미경상에서 탄선이나 브라켓에 손상은 발견되지 않았다. 마찰력의 양상이 브라켓의 재질로 추측할 수 있는 것과는 다르게 나타난 결과로 보건대 심미 브라켓이 스테인레스 스틸 브라켓에 비해 마찰력 면에서는 오히려 우수하거나 큰 차이가 없으므로 임상적으로는 마찰력은 크게 고려하지 않아도 되겠다. Objective: The purpose of this study was to evaluate how the friction that occurs during the sliding movement of the archwire through esthetic brackets is differently affected by bracket materials, slot designs, and tip angulations of the archwire. Methods: Eight types of brackets with 0.018 inch slots (composite: Brillant (BR); composite with metal slot: Spirit MB (SP); ceramic: Inspire (IN), Signature (SI), Cristaline V (CR); ceramic with metal slot: Clarity (CL), Luxi II (LU); and metal bracket: Integra (IT)), and placed into groups of 20 brackets in each group, were tested in artificial saliva with 0.018 inch stainless steel wire. The wire tip angulations were given as 0, 4 and 8 degrees. Results: CR group significantly showed the lowest frictional force with all wire tip angulations of 0, 4, and 8 degrees. IN significantly showed the highest frictional force (P < 0.001). BR (Polyoxymethylene) had significantly less frictional force than SP (Polycarbonate) (P < 0.001) and showed no significant difference between metal brackets. Friction was increased as the wire tip angulations were increased, but no notches were observed on any parts of the archwire. Conclusions : According to the results of this study, esthetic brackets are superior or similar to SS brackets from a frictional point of view.

일부 종합병원에 내원한 척추손상 환자에 대한 통계적 고찰

제영권,이동배,이영수 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

To find out the incidence and general characteristics of the spinal injury, this study was performed with analysis of 256 cases of spinal injured patients admitted in a general hospital in Tae jeon during the last 5 years, from January 1983 to December 1987, with the 9,077 total cases of injured patients including the spinal injury, admitted as the same period. We obtained the following results. 1. The incidence rate of the spinal injury among total injred patint was 2.8%, and among its causes, fall down was 10.7%, slip down was 4.1%, traffic accident was 2.4%, and direct blow and others was 0.7% in that order. The incidences of fall down, traffic accident, direct blow and others were increased anually. The seasonal incidence was 2.6% in Spring, 2.9% Summer and Autumn, and 3.0% in Winter. 2. The ratio between male and female was 2.1:1, and the most common cause of injury in female was slip down, but that in male was fall down, but traffic accident, direct blow and others were evenly distributed. 3. For the level of spinal injury, 46.1% was lumbar, 31.6% was thoracic, and 22.2% Was cervical vertebral injury. The injury to the cervical vertebrae was more frequent in traffic accident, but injury to the thoracic and lumbar vertebrae was more frequent in fall down cases. 4. For the nerve injury, 14.5% was complete paralysis, 9.7% was nerve root injury, and 7.0% was incomplete paralysis. Incomplete paralysis was more frequent in traffic accident cases, but complete paralysis and nerve root injury were frequent in fall down cases. 5. For the age distribution, the fifth decade was the most prevalent as 20.3%, but below the 19-year-old age group was the least as 3.9%. The incidence of third to sixth decade was higher. in male than female, but that of below the 19-year-old age group and over the 60-year-old age - group was reversed. 6. In the below the 19-year-old age group, the most frequent site of injury was cervical spine, but that was lumbar in third decade and that was thoracic in over the 60-year-old age group. The most frequent cause of injury in third, forth, and sixth decades was direct blow, but in fifth decade, that was fall down and in over the 60-year-old age group, that was slip down. 7. For the nerve injury, complete paralysis was frequent in sixth and fifth decade, incomplete paralysis was frequent in third and fourth decades, but nerve root injury was frequent in fifth decade. 8. For the comparison between male and female, cervical injury was more frequent in male, but lumbar injury was more frequent in female. Complete paralysis was more frequent in male than female. g, Most complete paralysis revealed in cervical and thoracic spinal injury, but most nerve root injury revealed in lumbar spinal injury. 10. There were 19.9% of spinal injured patients who had associated injury. The most frequent associated injury was extremity fracture as 58.7% and it was most frequent in traffic accident.

탄소성 유한요소법을 이용한 드로우비드 성형 및 인발공정 해석

정동원,이상제 濟州大學校 工科大學 産業技術硏究所 1998 尖端技術硏究所論文集 Vol.9 No.1

During the sheet metal forming, it is often necessary to control the rate of metal flow into the die cavity. The control of metal flow can be achieved through the blankholder, lubricant, draw-bead, or a combination. In this study among the conditions, examines the draw-bead. The role of control or restraining beads is to provide enough tension to deform the material plastically over the punch face, and to ensure proper shape fixing of the part. In this study, an elasto-plastic/static-implicit FE program is used for the analysis. It was assumed the result of numerical analysis is applicable to the practical industrial process by analyzing the draw-bead forming and traction process with erection.

탄소성 유한요소법을 이용한 드로우비드 성형 및 인발공정 해석

정동원,이상제 濟州大學校 産業技術硏究所 1998 산업기술연구소논문집 Vol.9 No.1

During the sheet metal forming. it is often necessary to control the rate of metal flow into the die cavity. The control of metal flow can be achieved through the blankholder, lubricant. draw-bead, or a combination. In this study among the conditions, examines the draw-bead. The role of control or restraining beads is to provide enough tension to deform the material plastically over the punch face. and to ensure proper shape fixing of the part. In this study. an elasto-plasticlstatic-implicit FE program is used for the analysis. It was assumed the result of numerical analysis is applicable to the practical industrial process by analyzing the draw-bead forming and traction process with erection.

Nd:YAG 레이저의 동작특성에 관한 연구 : 3단 병렬 순차 충·방전 방식 적용 3-mesh parallel sequence charge and discharge method

김희제,홍정환,김병균,박구렬,이동훈,김휘영 釜山大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.56 No.-

펄스형 Nd:YAG 레이저는 가공물질과 쉽게 반응하고, 램프에 의해서 연속발진은 물론 정상발진, Q-스이치 및 모드동기 발진까지 다양한 발진 형태가 가능하며 재료가공 및 계측용으로 널리 사용되어지고 있다. 재료가공에 있어서는 가공목적에 따라 에너지 밀도를 제어하는 것이 매우 중요하다. 에너지 밀도의 제어는 레이저 출력의 펄스반복률을 제어하는 방법이 주로 사용된다. 본 연구에서는 펄스형 Nd:YAG 레이저의 펄스반복률을 제어할 수 있는 3단 병렬 순차 충·방전 방식의 레이저 전원회로를 설계 및 제작하여 반복율에 따른 플래쉬램프의 전류파형 및 레이저 출력의 안정도와 신뢰성을 확인할 수 있었고, 펄스반복율은 30∼150[pps]까지, 30[pps]씩 증가시켰을 경우, 레이저 출력 효율은 약 5% 씩 감소한 반면, 축력은 약 4W 씩 증가하였다. A pulsed Nd:YAG laser interacts with processing materials easily, having different kinds of oscillators, such as CW by lamp, Q-switching, mode locking and so on. A pulsed Nd:YAG laser has been used in a wide variety of fields : measuring, materrial processing, and so on. In a material processing, it's very important to control an energy density according to the processing purpose. It is mainly used to control the energy density to vary pulse repetition rate. In this study, we designed and fabricated the 3-mesh parallel sequency charge and discharge circuit of which the pulse repetition was to be controlled. As increasing a repetition rate, we could find the stability and the reliability of laser output as well as flashlamp current waveform. When increasing a repetition rate from 30 to 150[pps] by 30[pps], we also found that the efficiency of lase output decreased by about 5%, while the output increased by about 4W.

中國 會社法上 土地使用權 出資에 관한 연구

趙東濟 한국기업법학회 2003 企業法硏究 Vol.14 No.-

The basic concept formed by the 1988 amendments to the Constitution is the separation of land use rights from the ownership of land. Subsequently, a series of laws and regulations have been promulgated to perfect the legal framework of China' s land use system. According to the Constitution, all land located in urban areas is owned by the State, while the land in mal and city suburban areas is collectively owned. Collective owners of land generally include farmer economic collectives, village communities or township farmers collectives. In other words, all land is publicly owned by either the State or the collectives. On the other hand, land use rights are distinguished as type of intangible property, and may be sold by the State to various land users including companies, enterprises, organizations, or individuals for value. Land users who have acquired land use rights from the State may, in a further step, sell or transfer in some other way, the land use rights to third parties, but the land always remains in public ownership. It is critical for investors to locate a good site and acquire legally transferred land. As detailed above, the land use rights may be obtained mainly by means of transfer, lease, allocate, purchase or equity contribution. Each method involves different legal implication, requirements and procedures. Therefore, foreign investors have to take all necessary precautions to examine the origin of land and distinguish the nature of transfer. It must be ensured that all necessary legal procedures have been gone through and every land-related document is in place.