C형 간염바이러스항체 검출을 위한3세대 효소면역측정 시약의 비교

이장혁,서순팔,기승정,송정원,신명근,신종희,양동욱,김세종 대한임상병리학회 1997 대한임상병리학회지 Vol.17 No.4

구속된 비행 청소년들의 석방 후 6개월 이내 재범의 예측요인

서동혁,정선주,손창호,김원식,고승희,함봉진,조성진,김영기,이중재 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : 본 연구는 범법행위로 인해 검참에 구속된 청소년들의 6개월 이내 재범여부를 예측할 수 있는 요인을 분석함으로써 재범의 가능성이 높은 청소년들을 조기에 선별하여 적절한 중재를 시행하기 위한 목적으로 시행되었다. 방 법 : 검찰에 구속된 후 교도소나 소년원에 수감되지 않고 석박된 남자 청소년 125명을 대상으로 하였다. 범죄기록 검토를 통해 사회인구학적, 범죄관련 변인들에 대해 조사하였고, 가족환경 및 부모양육태도, 정신병리, 성격장애, 도덕발달수준 등과 연관된 변인을 알아보기 위해, 부모-이동 갈등해결척도(CTSPC), 한국판 가정환경척도(FES), 한국형 부모양육행동척도, 간이정신진단검사(SCL-90-R), Beck 우울증척도, Beck 불안 척도, 한국판 청소년용 도덕발달수준 평가도구와 한국판 성격장애검사(PDQ-R)를 시행하였다. 결 과 : 전체 연구대상 125명 중 55명 (44%)이 석방 후 6개월 이내에 1회 이상의 재범을 행하였다. 재범군은 비재범군에 비해 구속당시 나이가 어리고, 신체적 학대력이 높았으며, 도덕발달수준이 낮고, SCL-90-R의 적대감척도점수가 높으며 PDQ-R의 반사회적 인격장애에 해당되는 경우가 많았다. 두 집단간 가족환경이나 부모양육태도에는 유의한 차이가 나타나지 않았다. 재범군은 폭력범죄로 구속된 경우가 비재범군에 비해 적었고 첫 범죄시 연령이 어리고 전과가 있는 경우가 많았다. 로지스틱 회귀분석 결과, 재범에 대한 예측요인으로 첫 범죄당시 연령(오즈비=2.91), 반사회적 성격장애(오즈비=2.85), 신체적 학대력(오즈비=2.65)의 세 변인이 포함되었으며, 재범여부에 대한 판별력은 72.8%로 나타났다. 결 론 : 본 연구결과 구속된 청소년들의 재범률이 매우 높다는 사실과 범죄행위에 가담한 연령이 어릴수록, 반사회적 성격장애가 있고 성장과정 중 부모로부터 학대를 받은 경험이 있을수록 반복적인 범죄를 저지를 위험도가 높다는 것을 알 수 있었다. 향후 비행 청소년들의 재범을 예방하기 위해서는 이러한 특성을 가진 고위험군에 대한 조기개입 및 적응을 돕기 위한 프로그램의 개발이 중요할 것으로 사료된다. Objectives : This study was performed to investigate the factors predicting recidivism within 6months after release in arrested juvenile delinquents for proper screening and intervention of high-risk-subjects. Methods : The subjects consisted of 125 arrested male adolescents who were released after legal procedure in prosecutor office and court. The socio-demographic and crime-related characteristics. Were evaluated by police records, and the familial, psychopathology and personality characteristics, and the level of moral development measured by the Conflict Tactics Scale(CTS), Family Environment Scale(FES), Parental Behavioral Inventory, Symptom Checklist-90-Revised(SCL-90-R), Beck Depression Inventory, Beck Anxiety Inventory, Korean form of Moral Developmental Inventory for adolescents, and Personality Disorder Questionnaire-Revised(PDQ-R). Results : The recidivism rate within 6 months after release was 44% of the initial sample, Recidivists were younger and had higher scores on Anger-hostility scale of SCL-90-R and lower principle morality score than nonrecidivists. More recidivists had history of physical abuse and antisocial personality disorder on PDQ-R than nonrecidivists. They also showed the crime-related characteristics of lower percent of violence crime, higher incidence of previous conviction, younger age of the first crime. Among those variables, logistic regression showed that age of first crime, antisocial personality disorder, and history of physical abuse best predicted the recidivism within 6months after release. Conclusion : These results of present study suggest that the recidivism rate of arrested male adolescents is very high, and the age of first crime, antisocial personality disorder and history of physical abuse were key factors predicting recidivism. To prevent repeated crime of delinquent adolescents, the development of programs for those high-risk groups to help rehabilitation and adaptation in community would be essentil.

건물의 지하구조변경에 따른 지상층의 실내 라돈농도에 관한 실험적 연구

차동원,서승직 대한건축학회 2003 대한건축학회논문집 Vol.19 No.2

The Test Cells that had been built and utilized for the previous study titled "An experimental study on variation of indoor radon concentration and soil gas analysis" was utilized for this study as well to find out what are the important differences in indoor radon concentration when the test cells are with or without basement. For this purpose, the basement was filled with imported soil after the previous study to have changes in substructure as follow; 1) filled up to 30cm below ground floor slab to make floating slab, 2) filled the unfilled space to make grade-on slab, and 3) substitute top 10cm thick soil with gravel underneath ground floor slab to provide high permeability. The indoor concentrations of ground floor at the above three status were measured and analyzed in regression method to compare with each other and with when the basement was not filled.

인접건물에 의한 반사주광 성능에 대한 평가

최원기,이동권,안명환,서승직 대한건축학회 2004 대한건축학회논문집 Vol.20 No.6

This paper is focused on evaluation of daylight reflecting performance from the adjacent building for improvement of poor environment conditions in a metropolitan area. The numerical model developed can be used for evaluation of daylight reflecting performance. As a result comparison of our simulation programs and commercial softwares, it was verified that there was no difference between two results. In this study, the sensitivity analysis of environmental performance factors of daylight reflecting from the adjacent building were examined, analysed and presented as a solution method for improvement of building environments. The results were proved to be an effective control methods for improvement of building environment, especially in a metropolitan area.

High Performance Liquid Chromatography를 이용한 Hemoglobin A1C 측정

변동원,서교일,유명희,김극배 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Hemoglobin AIc(HbAlc) has been known to be an index of long-term glycemic control (6-8weeks), and offers several practical advantages for screening of diabetes mellitus and evaluation of effects of treatment. Authors introduced to measure and investigate HbAlc levels by high performance liquid chromatoraphy (HPLC ; LDC Milton Roy, USA), with cation exchange column, Mono S HR 5/5 (Pharmacia). The results were as follows; 1. The mean HbAlc level in normal adult control group (n=50) was 4.13±0.25% (Mean±S.D). 2. Within-run precisions of HbAlc levels measured by HPLC were 4.39±0.01% (Mean±S.D.), 1.41(C.V.) in normal control, and 8.95±0.02% (Mean±S.D.), 1.65(C.V.) in intermittently treated diabetic patients, and 11.02±0.01% (Mean±S.D.) 2.93(C.V.) in untreated diabetic patients. 3. Between-run precision of HbAlc levels measured by HPLC were 4.35±0.01% (Mean±S.D.), 2.76(C.V.) in normal control, and 8.98±0.01% (Mean±S.D.), 1.22(C.V.) in intermittently treated diabetic patients, and 10.95±0.15% (Mean±S.D.), 3.51(C.V.) in untreated patients. 4. The peak level of HbAlc was obtained in about 9 minutes and the whole program could be completed within 17 minutes. 5. Blood specimens could be stored for as long as 8 days at 4℃ without changes of HbAlc levels. These results suggest that the measurement of HbAlc by HPLC using cation exchange column is so accurate, simple and rapid that the clinical use is more wider.

합병증이 동반된 Meckel씨 게실 2례 보고

정병욱,박동일,이준희,서정욱,원유홍,김웅,신현종,권영무 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

합병증이 동반된 Meckel씨 게실을 가진 환자의 치료에 대한 필요성은 과정이 문제이다. 하지만 우연히 만나는 게실의 처치는 논란 중이다. 부수적인 게실 절제술(incidental diverticulectomy)의 제안자는 증상이 있는 게실의 외과적 처치는 중요한 이환 및 사망률은 지적한다. 이를 반대하는 사람들은 전 생애를 통해 합병증의 위험성이 낮게 나타나므로 필요가 없다고한다. 게실의 예방적 제거는 개복술시 우연히 발견 될 때 시행한다. 이는 남아있는 게실이 나중에 합병증을 일으키는 것보다 술후 합병증의 위험성이 매우 적음을 알 수 있다. 저자들은 합병증이 동반된 Meckel씨 게실 2예를 경험하였기에 문헌 고찰과 더불어 보고하는 바이다. The necessity for therapy with complicated Meckel's diverticular is a matter of course.However, management of the incidentally encountered diverticulum is controversial. Proponents of incidental diverticulectomy point to the significant morbidity and mortality rates of surgical treatment of symptomatic divenicular. Other authors base their opposition to incidental diveniculectomy on the low risk of complications developing during lifetime. Prophyillctic removal of the diveniculum is indicated when it is found incidentally at laparotomy, because there are few postoperative complications and the risk exists that the remaining diverticulum may be the cause of later complication. The 2 cases of complicated Meckel's diverticulum are reported with a brief review of literature.

韓國人 兒童의 顔面輪廓에 關한 頭部放射線學的 硏究

張英一,南東錫,梁源植,徐廷勳 대한치과교정학회 1976 대한치과교정학회지 Vol.6 No.1

This study was undertaken to investigate the values of the cephalometric standards of Korean children which consisted of 57 boys and 61 girls with normal occlusion and harmony of the facial musculature. The following conclusions were obtained. 1) The relatively vertical inclination of nasal bone and flat contour of the frontal bone contribute to the flattening of the upper face. 2) Slight lack of chin prominence characterizes the lower face while procumbent incisors and their alveolar bone dominate the middle face. 3) A caudal skull base inclination is probably the most specific feature for Korean.

Combination treatment for onychomycosis using 1,064 Nd:YAG laser and efinaconazole 10% topical solution

( Sang Ju Lee ),( Dong Woo Suh ),( Won Soon Chung ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Onychomycosis is one of the most common nail disease around the world. No specific treatment other than drug therapy and surgery was suggested till present. Systemic antifungal drugs for onychomysosis are effective. However, they require a long treatment time and not suitable for people with other systemic disease. Furthermore, they may cause many side effects such as liver disease. Also, many patients prefer topical drugs or physical treatment. Objectives: The objective of this study was to evaluate the efficacy of combination treatment with a 1064 Nd:YAG laser and efinaconazole 10% Topical Solution. Methods: Ten patients with onychomycosis were treated with 1064 Nd:YAG laser (PinPointe FootLaser, Cynosure, Westford, MA, USA) once a month with application of 10% eifnaconazole solution(Jublia, Dong-A EST) once a day. The effectiveness of treatment were evaluated with before and after photographs. Results: Improvement were shown in 90% of patients after the treatment. However, 10% of patients had no response. Conclusion: This clinical study suggests that combination treatment of a 1064 Nd:YAG laser and efinaconazole 10% Topical Solutionis an effective, safe, and convenient treatment method for onychomycosis.

각종 골대체물질들의 골형성능에 관한 비교연구

설정현,최원희,김정철,홍정수,서동보 大韓成形外科學會 1992 Archives of Plastic Surgery Vol.19 No.4

We studied the bone forming capacity of the various bone substitute materials for the confirmation of bone regeneration with each case i.e Hydroxyapatite(SURGIBON), kiel obne, B.O.P. and bone dust. The bone dust was used for control. In 18 New Zealand white rabbits, four partial thickness bone defects were created on the outer table of parietal bone, which were measured 1.5mm in depth x 8mm in diameter. Bone substitute materials were filled in each bone defect. The animals were sacrified at 2, 4, 6, 8 weeks after taking a plain skull film, and then both macroscopic and microscopic examinations were done. The results were as follows : 1. Hydroxyapatite : good bone regeneration with moderately increased eosinophil. 2. KIEL BONE : no bone regeneration and markedly increased eosinophil. 3. B.O.P. : no evidence of bone growth during postoperative 8 weeks. 4. BONE DUST : persistent osteoblast existed during experimental period, more likely as own bone. We summarized that the hydroxyapatite is a biocompatible matrix implantable as a bone graft substitute and more bone regeneration than other bone substitutes during the experimental period.

사람-사람 하이브리도마의 생산을 위한 fusion partner cell의 개발

안지영,김혜원,서동상 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

This study was performed to establish human hybridmyeloma cell lines as fusion partner cells for producing human-human hybridoma. Human myeloma, SKO-007(J3), and human cervix epitheloid carcinoma cell line, HeLa MR, were fused by using with 50% PEG, and cultured in RPMI 1640 medium containing 15% FBS. Hybrids of SKO-007(J3) and HeLa MR were selected in RPMI 1640 media containing 6-thioguanine(6-TG ; gradually increasing concentration from 10 ㎍/ml to 20 ㎍/ml, and then gradually decreasing to 10 ㎍/ml) for 6 weeks. 6-TG resistant cells were collected and cloned by limiting dilution method. The fused myelomas with HeLa MR grew more rapidly than the fused cells with a small number of HeLa MR. Their doubling time was 72 hours.