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기계 학습을 이용한 전염병 통제를 위한 다중 에이전트 시스템
Malintha De Silva, K. Dilusha 전북대학교 일반대학원 2019 국내석사
Emerging infectious diseases have become a threat to humanity and it is still a challenging problem. Epidemiology is one of the important topics in health industry to be addressed to find fast solutions with different researches. An infectious disease can spread over entire population within a short period of time. Humankind has suffered from epidemic outbreaks throughout the history and many infectious diseases caused devastating situations. Until now, existing systems for healthcare are insufficient for act immediately. Multi-Agent healthcare systems provide considerable solutions but such systems are not properly developed for control infectious diseases. In this dissertation, we propose a multi-agent system for control infectious diseases with extended capabilities for identify and remove infected people from a population. This system prevents an infected person to be in a population by predicting and identifying them so that further spreading of the infectious diseases can be greatly reduced. The goal of this work is to improve the quality of service in healthcare and to protect healthy people from epidemics. 부상하는 전염병은 인류에 위협이되었으며 여전히 어려운 문제입니다. 역학은 여러 연구를 통해 빠른 해결책을 찾기 위해 보건 산업에서 중요한 주제 중 하나입니다. 전염병은 짧은 기간 내에 전 인구에 퍼질 수 있습니다. 인류는 역사를 통해 유행성 전염병으로 고통을 겪었고 많은 전염병으로 치명적인 상황이 발생했습니다. 지금까지 건강 관리를위한 기존 시스템은 즉시 행동하기에 충분하지 않습니다. 다중 에이전트 의료 시스템은 상당한 솔루션을 제공하지만 그러한 시스템은 감염성 질병을 통제하기 위해 적절하게 개발되지 않았습니다. 이 논문에서, 우리는 감염된 사람들을 식별하고 감염자로부터 제거하기위한 확장 된 능력을 가진 제어 전염병을위한 다중 에이전트 시스템을 제안한다. 이 시스템은 전염병의 확산을 크게 줄일 수 있도록 감염된 사람을 예측하고 식별하여 감염된 사람을 예방합니다. 이 작업의 목적은 의료 서비스의 질을 향상시키고 건강한 사람들을 전염병으로부터 보호하는 것입니다.
LIYANA ARACHCHILAGE DINITHI SANDUNIKA DE SILVA 충북대학교 2022 국내석사
국문요약 Vibrio harveyi은 동물 및 사람에게 있어서 감염을 일으키는 병원성 세균으로 널리 알려져 있다. 이 연구의 목표는 국내에서 양식, 판매하고 있는 양식 해산어류로부터 분리된 Vibrio harveyi의 병원성 인자 및 항생제 내성 인자의 특성과 유형을 분자생물학적 기법을 통하여 분석하여, 감염 어류의 섭취로 인한 인수 공통 전염의 가능성을 제시하는 것이다. 이 연구에서는 Vibrio harveyi로 동정되는 49개의 분리주를 국내에서 양식하는 여러 종류의 해산어류로부터 분리되었다. 생화학적 검사 결과, DNase 생성(81.63%), 용혈(α= 75.51%, β=82 12.25%), gelatinase 활성 (71.43%), protease 생산 (71.43%), phospholipase 생산(65.31%), 그리고 lipase 생성 (34.69%)이 분리주에서 확인되었다. 병원성 유전자는 PCR을 통해 VPI (57.14%), tlh (44.90%), tdh (36.73%) , toxR (22.45%) VAC (12.24%) 그리고 ctxAB (8.16%)이 확인되었다. 또한 대부분의 분리주들은 ampicillin 내성을(77.55%) 가지는 것으로 확인되었고, oxacillin (69.39%), nalidixic acid (53.06%), amoxicillin (46.94%), oxytetracycline (46.94%), colistin sulphate (34.69%), fosfomycin (34.69%) chloramphenicol (32.65%), streptomycin (32.65%), cephalothin (28.57%), oxytetracycline (26.53%), ceftriaxone (20.41%) erythromycin (14.29%), 그리고 cefoxitin (12.24%) 내성이 확인되었다. 이들 중 37개(76%)의 분리주는 다중 항생제 내성(MAR) 지수가 ≥ 0.2으로 나타났다. PCR을 통해 각 81.63%, 67.35%, 61.22%, 46.94%, 44.90%, 44.90%, 36.73%, 18.37%, 10.20%, 10.20%, 8.16%, 그리고 6.12%의 분리주에서 tetB, qnrA, intI1(Class 1 integron integrase), aac(6’)-Ib, blaSHV, blaCTX-M, strA-strB, tetA aphAI-IAB, qnrC, qnrS, 그리고 blaTEM 유전자가 각각 존재함을 확인하였다. 이 연구의 결과를 통해 국내에서 양식, 판매되고 있는 해산어류로부터 분리된 Vibrio harveyi의 병원성과 다중약제에 대한 내성을 확인하였으며, 이들 Vibrio harveyi이 감염된 해산 어류를 섭취함으로써 사람에게 감염하여 위해를 일으킬 수 있다고 사료된다. Abstract Vibrio harveyi is a significant cause of infection in both marine animals and humans. It has been reported frequently in seafood-borne infections worldwide. This study was conducted to determine the potential health impact of the V. harveyi isolated from marine food fish cultured in Korea concerning their virulence and antimicrobial resistance. A total of 49 V. harveyi samples were isolated by biochemical tests and PCR method. Phenotypic detection of virulence factors resulted DNase activity (81.63%), hemolysis (α=75.51% and β=12.25), gelatinase activity (71.43%), protease production (71.43%), phospholipase activity (65.31%) and lipase production (34.69%). Virulence genes, including VPI, tlh, tdh, toxR, VAC and ctxAB were detected in 57.14%, 44.90%, 36.73%, 22.45%, 12.24% and 8.16% of the isolates, respectively. Resistance to ampicillin (77.55%), oxacillin (69.39%), nalidixic acid (53.06%), amoxicillin (46.94%), oxytetracycline (46.94%), colistin sulphate (34.69%), fosfomycin (34.69%) chloramphenicol (32.65%), streptomycin (32.65%), cephalothin (28.57%), oxytetracycline (26.53%), ceftriaxone (20.41%) erythromycin (14.29%) and cefoxitin (12.24%) was detected in disc diffusion assay. Most of the isolates were classified as multidrug-resistant as they scored multiple antimicrobial resistance (MAR) index ≥ 0.2. Furthermore antimicrobial resistance genes tetB, qnrA, intI1 (Class1 integron integrase), aac(6’)-Ib, blaSHV, blaCTX-M, strA-strB, tetA, aphAI-IAB, qnrC, qnrS and blaTEM were found in 81.63%, 67.35%, 61.22%, 46.94%, 44.90%, 44.90%, 36.73%, 18.37%, 10.20%, 10.20%, 8.16% and 6.12% of the isolates, respectively. In conclusion, the development of antimicrobial resistance among V. harveyi will ultimately reduce the efficacy of antimicrobials used for treating and can favor the development of more virulent V. harveyi strains. Keywords: Vibrio harveyi, virulence factors, antimicrobial resistance, seafood
Kaluthanthri P. S. De Silva Green School Graduate School of Energy and Environ 2021 국내석사
As a party to the United Nations Framework Convention on Climate Change (UNFCCC), Sri Lanka has signed and ratified the Paris Agreement and pledged their national obligation under the, Nationally Determined Contributions (NDCs) to reduce the GHG emissions level against Business As Usual (BAU) scenario by 10% from the transport sector as consider highest GHG reduction sector in the country. According to the CEB Long Term Generation Expansion plan transport emitted 49 percent of CO2 from the total emission level of the country. This study analysis effectiveness of policies enforced in transportation and analyzes the existing energy demand as well as the level of CO2 emission of this sector if the current polices are remained until 2040. The LEAP model - Long-range Energy Alternative Planning System was used to predicted the energy demand and level of CO2 emission of the sector. This research concluded result using two policy scenario as improved fuel efficiency and Hybrid/Electric car scenario. In Hybrid/Electric car scenario two types of vehicles are considered such as hybrid and electric vehicles. Estimated result shows that under these two types of scenario CO2 reduction targets achieved only 8.2% by 2040. Findings shows that it is compatible with national GHG reduction targets in Sri Lanka transport sector therefore essential implement powerful strategies and polices to meet the such targets in transport sector.
Factors Associated with Depression in Hospitalized Patients with Myocardial Infarction in Sri Lanka
K.H.R. Sandyani De Silva 인제대학교 일반대학원 2017 국내석사
Back ground & Purpose- Myocardial Infarction (MI) is the leading cause of death in Sri Lanka. Depression has been known to be risk factors for developing Cardio Vascular Disease (CVD), owing to its high prevalence and its influence on MI. Although depression of MI has almost reached to epidemic proportion in Sri Lanka, the reason for high risk of depression of MI among Sri Lankans is still unclear. This study was conducted to identify the severity of depression and its correlates in hospitalized MI patients in Sri Lanka. Methods- This study was performed from July to August in 2016. A descriptive study was carried out among 125 patients with MI was admitted in General Hospital in Sri Lanka. An interview with self-administered questionnaire was used to collect data. Depression was measured by the Hospital Anxiety and Depression Scale. Results-The mean severity of depression was 8.92. Severity of depression was strongly correlated with symptom experience. All the predictors including age, gender, symptom experience, perceived social support explained 31.0% of the total variance of severity of depression. Symptom experience was the most significant predictor for the severity of depression. Age was also effected on severity of depression. Conclusion- Assessment is necessary in order to identify depression and factor that associated depression such as symptom experience for the hospitalized patients with MI based on the current study. Especially, clinicians should concern the hospitalized patients who are younger and middle aged as well as older, with higher symptom experience. i
MEREGNGNAGE ISURU UMANDA DE SILVA 부경대학교 대학원 2019 국내석사
This study focuses on using the Individual Travel Cost Method (ITCM) as a non-market valuation technique to estimate the economic value of sea whale-watching based on coastal and marine tourism in Mirissa, the Southern Province of Sri Lanka where no previous studies of this kind have been conducted before. In this study, the visit demand function of the site is estimated after collecting the related questionnaires and then the consumer’s surplus is calculated. Two scenarios are taken into account; in the 1st scenario, the time value which is being spent by an individual to reach the site considered in the evaluation of time opportunity cost, but in the 2nd scenario, it has been not been considered. The count data models including zero truncated Poisson regression (ZTPR) model and zero truncated negative binomial regression (ZTNBR) model are applied to estimate the consumer surplus (CS) with a sample size of 241. Mirissa beach is used as a case study based on the fact that a reasonable number of visitors visit the beach, and also because Mirissa is a popular hotspot known around the world. Given the nature of the study, an onsite survey is inevitable. The questionnaire used for the onsite survey is designed to capture socioeconomic variables about visitors (such as Age, Income, Edu, Employment Status, Gender and Nationality), travel cost component variables (such as TTC, RTT_time, D_mirissa, No_visits) and the willingness to pay (WTP) of visitors (in the form of conservation value). The count data (with a sample size of 241) that was generated from the survey is modelled with the ZTPR and ZTNBR models. The econometric estimations show that consumer surplus (CS) estimates per trip per visitor per year in ZTNBR, which avoids the over-dispersion problem with ZTPR and based on these econometric results, CS estimates per trip per visitor per year were computed for different categories of visitors. For foreign sample, ZTNBR generates $3634 and for locals $24, and for the aggregation of the national level the annual total economic value of foreign visitors for whale-watching is estimated to be $556,884,376 and for locals $310177. Foreigners’ are willing to pay (WTP) a maximum of $70 and locals are $11.11 per visit to the improvement and development of Mirissa and as a conservation value.
Senasige, Chalani Janesha De Silva Sungkyunkwan University 2025 국내석사
이 디자인 기반의 논문은 스리랑카 미토타물라(Meethotamulla) 쓰레기 매립지의 잠재적인 변화 가능성을 조경학적 관점에서 탐구하여, 해당 부지를 자연 기반의 공간적 담론으로 재구성하는 방안을 제안한다. 한때 스리랑카에서 가장 비위생적인 쓰레기 매립지 중 하나였던 미토타물라 부지는 심각한 환경, 사회, 공중보건 문제를 야기했으며, 이는 2017년 4월 대규모 매립지 붕괴로 이어졌다. 이 참사는 30명 이상의 사망자와 다수의 가옥 및 재산 피해를 발생시켰고, 올바른 폐기물 관리와 폐쇄 후 매립지 복원의 시급성을 전국적으로 환기시켰다. 이에 대응하여 2020년 스리랑카 도시개발청(UDA)은 안정화 조치와 토양 복토 작업을 실시하였으나, 해당 조치들은 국제적인 매립지 폐쇄 기준을 충분히 충족하지 못하였다. 초기에는 본 부지를 공원으로 전환하려는 계획이 제안되었으나, 재정 부족으로 인해 사업은 중단되었고, 현재는 비공식적인 폐기물 투기로 인한 환경 훼손에 다시 노출된 채 방치되어 있으며, 주변 도시 및 지역사회와도 단절된 상태로 남아 있다. 본 연구는 콜롬보 도심 내에서의 미토타물라 부지의 전략적 위치성과 공공 개방 공간의 절대적 부족 문제를 인식하고, 해당 부지를 다기능적 생태공원으로 재창조하는 조경 설계안을 제시하였다. 연구는 문헌 고찰, 국내외 매립지의 공원화 사례 분석(난지도 공원–한국, 아리엘 샤론 공원–이스라엘, 프레시킬스 공원–미국, 오클라 매립지 복원 프로젝트–인도), 대상지 분석을 포함한 혼합 연구 방법을 채택하였다. 제안된 설계는 생태 복원과 여가 및 레크리에이션 프로그램, 문화 및 예술, 환경 교육 및 인식 증진 요소를 통합하여 인간과 자연 간의 지속 가능한 관계 형성을 유도하고, 환경 회복력과 지역 사회의 삶의 질 향상을 목표로 하였다. 지금까지 시도된 바 없는 스리랑카의 대규모 쓰레기 매립지를 공원으로 전환하기 위한 설계안을 제안함으로써, 본 연구는 향후 탈산업화 및 매립지 폐쇄 지역의 재생을 위한 조경적 실천에 중요한 기준과 방향을 제시하는 데 기여할 것이다. This design-based thesis investigates the potential transformation of the Meethotamulla waste landfill site in Sri Lanka into a museum park through the lens of landscape architectural intervention. Formerly one of the largest unsanitary landfills in the country, the Meethotamulla site posed severe environmental, social, and public health risks, which culminated in a major landfill collapse in April 2017. This tragic incident resulted in the loss of over 30 lives and the destruction of numerous homes and properties in the surrounding community, drawing national attention to the urgent need for proper waste management and post-closure rehabilitation. In response, stabilization measures were initiated, and soil capping was implemented by the Urban Development Authority (UDA) in 2020; however, these interventions did not fully adhere to international standards for landfill closure. Although initial plans were proposed to convert the site into a public park, the project was halted due to lack of funding. As a result, the site remains neglected, vulnerable to renewed environmental degradation from informal waste dumping and disconnected from the surrounding urban and social fabric. Recognizing the site’s strategic location within Colombo’s urban fabric and the acute shortage of public open spaces in the area, this study aims to develop a comprehensive landscape architectural proposal that transforms the landfill into a living landscape museum park. The research adopts a mixed-method approach, combining a literature review and global case study analyses of landfill-to-park conversions, including Nanjido Park (South Korea), Ariel Sharon Park (Israel), Freshkills Park (USA), and the Okhla Landfill Rehabilitation Project (India), along with a site-specific contextual analysis. The proposed design integrates ecological restoration, recreational programming, cultural functions, and education and awareness initiatives to foster a sustainable relationship between humans and nature, promoting environmental resilience and community wellbeing. As one of the first of its kind in Sri Lanka, this thesis presents a pioneering framework for transforming landfills into parks, setting a precedent for future rehabilitative landscape architecture practices in post-industrial and post-landfill sites.
Silva de la Mora, Flavio Gabriel University of California, Berkeley ProQuest Disser 2017 해외박사(DDOD)
소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.
This dissertation uses multiple lines of evidence to understand production, exchange and crafting in agrarian societies with a focus on the Northwestern Mayan Lowlands during the Late Classic Period (700-850 A.D). The organization of production in Pre-Columbian times is poorly understood, yet exchange is believed to be critical to the development of sociopolitical relations in ranked agrarian societies, like those in Mesoamerica. This dissertation will examine how the material culture of everyday activities, especially those related to production and exchange, manifests in the archaeological context and reflects communities of practice. It will evaluate two models of control of production and exchange of craft products, primarily lithic products (stone tools) in state-level societies using evidence from regional surveys, household excavation, and archaeometric studies of stone tools. One model proposes that with the development of sociopolitical hierarchies, elites monopolize or centrally control production and circulation of craft goods, even when these productive activities continue to be practiced in decentralized locations, such as dwellings. The second model suggests that craft producers working in decentralized locations may have controlled most or all of the organization of production and distribution of craft products. Through extensive regional study, I mapped terrestrial and fluvial communication routes and their relationship to settlement pattern and site distributions. I established the least costly, and thus most likely patterns of travel in the region using analytic tools such as GIS. Including excavation at a major site, Chinikiha. Preliminary research established the presence of areas of production of chipped stone tools in an independent residence outside the palace zone. The excavations sought to understand domestic production and local patterns of production and exchange and tested theories around daily practice and social learning. The study includes a larger sourcing analysis of obsidian stone tools and debitage in done with Energy Dispersive X-RayFluorescence (EXDRF) to reconstruct the movement and exchange distribution. The resulting archaeological analysis and assemblages will reflect local techniques of production, the materials utilized, types of artifacts produced, and consumption practices that will result in a better understanding of the practices of procurement, production, exchange, consumption, social organization, and differentiation, as well as the communal practices in the region.
Rank constrained homotopies of matrices and the Blackadar-Handelman conjectures on C*-algebras
De Silva, Kaushika Purdue University ProQuest Dissertations & Theses 2016 해외박사(DDOD)
소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.
Rank constrained homotopies of matrices. For any n ≥ k ≥ l ∈ N, let S( n,k,l) be the set of all non-negative definite matrices a ∈ Mn(C) with l ≤ rank a ≤ k. We investigate homotopy equivalence of continuous maps from a compact Hausdorff space X into sets of the form S(n,k,l). From [37] it is known that for any n, if 4dim X ≤ k-l where dim X denote the covering dimension of X, then there is exactly one homotopy class of maps from X into S(n,k,l). In Section 3.1 we improve this bound by a factor of 8 by confirming C(X,S( n,k,l)) to have exactly one homotopy class of maps when [floor bracket] (dim X/2[end floor bracket] ≤ k - l.) This in particular means pir(S( n,k,l))=0. Blackadar-Handelman conjectures on C*-algebras. Let DF(A) denote the set of all dimension functions on a C*-algebra A and let LDF(A) be the set of all s ∈ DF(A) which are lower semicontinuous. It is well known that DF(A) is naturally identified with the state space of the Cuntz semigroup W(A). From [6], LDF(A) bijectively corresponds to the space of all normalized quasitraces QT(A) through a continuous affine map. [6] conjectures LDF( A) to be pointwise dense in DF(A) and DF(A) to be a Choquet simplex. In Theorem 5.1.1 we provide an equivalent condition for the first of these conjectures for unital A. Applying this condition we confirm the first conjecture for all unital A for which either the radius of comparison is finite or the semigroup W( A) is almost unperforated (Theorem 5.2.5). for every $r\leq 2(k-l)+1$. Our results are achieved through applications of the techniques developed in [8] and [33]. If LDF(A) is dense in DF(A) for an unital A that has only finitely many extreme points in QT(A), through a simple application of Krein-Milman Theorem we note that DF(A)=LDF(A) and that DF(A) is affinely homeomorphic to QT(A). Together with results on the first conjecture this confirms the second conjecture for a new class of C*-algebras. Possibility of extending these results to inductive limits remain an open question. In general the second conjecture is true for any unital A for which (ordered) Grothendieck group K0( A) of W(A) has Riesz interpolation property [15] and every known confirmation of the second conjecture is achieved by showing Riesz interpolation hold for K0( A) [1,9,29]. We consider a stably approximate version of interpolation that is weaker than the classical Riesz interpolation. In fact it is easily seen that this property is even weaker than the asymptotic interpolation property considered in [28]. In Corollary 6.4.3 we confirm DF(A) to be a Choquet simplex for any unital A for which W(A) satisfies this weaker notion of interpolation. While Corollary 6.4.3 has the scope of confirming the second conjecture for a broader class of C*-algebras, finding a `good' class of C*-algebras in which W(A) exhibits stably approximate interpolation but does not satisfy Riesz interpolation remains open.