저체중 출생이 학동기 및 청소년기 소아 천식의 중증도에 미치는 영향에 대한 고찰

정훈 ( Hoon Jeung ),김형대 ( Heung Dae Kim ),이윤진 ( Yun Jin Lee ),이균우 ( Kyun Woo Lee ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2006 소아알레르기 및 호흡기학회지 Vol.16 No.1

목 적 : 본 연구는 저출생 체중아로 출생한 소아에 있어서 학동기 및 청소년기 소아 천식의 중증도에 미치는 영향에 관해서 후향적으로 검토하였다. 방 법 : 대동병원 소아과와 호흡기내과에 통원 중에 있거나 부산 동래구 및 연제구 소재 개인의원에서 대동병원으로 전원 된 천식 환자 중에서 8세 이상 18세 이하의 소아 및 청소년을 대상으로 출생체중을 기준으로 1,500 g 이상 2,500 g 미만인 15명을 추출하여 연구군으로 하고 출생체중 2,500 g 이상이며 연구군의 나이에 일치하는 순서대로 2명씩 추출하여 이 30명을 대조군으로 하였다. 결 과 : 양군을 비교한 결과 천식 중증도는 연구군에서 유의하게 높았다.(P=0.015) 또 흡입 스테로이드 약의 사용 빈도(증례군 13명/15명, 대조군 4명/30명 : P=0.0001)와 사용 기간에 있어서도 연구군에서 유의하게 높게 나왔다.(P= 0.009) 혈중 총 IgE치와 아토피피부염의 유병률은 대조군에서 높았다.(각각 P=0.007, P=0.0001) 폐기능 검사와 PC(20), 특이 IgE 항체는 두 군 사이에 유의한 결과를 볼 수가 없었다.(P>0.05) 결 론 : 천식의 중증도와 흡입 스테로이드 사용의 빈도와 기간 등으로 미루어 볼 때 저출생 체중은 소아 천식의 중증도를 증가시키는 요인 일 수 있음을 시사한다. Purpose : Over the past several decades, the survival rates of low birth weight(LBW; birth weight <2,500 g) infants have been improving. Many of these infants have had bronchial asthma(BA) at childhood and aldolescence. The aim of this study is to investigate whether LBW influenced the severity of BA in prealdolescent children and aldolescence by a retrospective case control study. Methods : 15 LBW children(1,500 g<birth weight<2,500 g) between 8 year-old and 18 year-old with BA visiting Dae-dong hospital as the case group were compared with 2 BA children to each case as the control group(total 30 children) on the basis of following criteria : the same age, he/she attended Dae-Dong hospital or local medical center after 8 years old, birth weight was more than 2,500 g. Asthma severity was modified from 2003 Guideline for management of childhood asthma at The Korean Academy of Pediatric Allergy and Respiratory Disease. PFT(Pulmonary function test) were measured using a portable spirometer. The value are expressed as percentage predicted using standard reference values. Total IgE and specific IgE Ab. were assessed by the PRIST method and MAST Allergy Test. Methacholine challenge test and PC20 was assessed by the Masterlab. Results : LBW group had : a significantly more severe symptoms between 8 year-old and 18 year-old than control group.(P=0.015) A significantly more used to ICSs(Inhaled corticosteroids) and add-on therapy than control group.(P=0.009)(P=0.0001) There were no significant differences in the PFT and PC(20) and specific IgE Ab. between LBW group and control group. But, total IgE level is higher in the control group than in the LBW group. Conclusion : These results suggest that LBW is a risk factor for the severity of BA. We suggest that infants with birth weight of less than 2,500 g have a more severe risk of asthma during prealdolescent children and aldolescence than who were birth weight of more than 2,500 g. [Pediatr Allergy Respir Dis(Korea) 2006;16:38-46]

교과내용학 : 동학에 나타난 고유사상 연구

김대훈 ( Dae Hoon Kim ) 한국윤리교육학회 2015 윤리교육연구 Vol.0 No.37

이 논문은 동학(東學)의 사상적 기저(基底)가 유교, 불교, 도교가 아닌 고유사상(固有思想)에 있음을 고찰한 글이다. 유·불·도(儒·佛·道)가 삼국시대에 전래된 이후 도교는 민간신앙(民間信仰)과 혼합되어 그 정체성이 뚜렷하지 않지만, 유교와 불교는 전통사상(傳統思想)으로 자리매김 하였다. 동학은 우리 민족의 종교이자 학문사상이기 때문에, 우리의 문화적 전통과 역사적 맥락에서 탐구되어야 한다. 그러나 유·불·도는 동학의 본질이 될 수 없다. 유교의 경우는 최제우(崔濟愚, 1824-1864)가 비록 조선의 선비로 자랐지만, 주유팔로(周遊八路)의 과정에서 유교의 한계를 직시하고 그러한 전통을 거부한다. 불교는 최제우로 하여금 유교적 지식인의 삶에서 깨달음의 종교적 삶으로 전환시키는데 기여하지만 동학과는 직접적인 관련성이 적다. 도교는 동학의 이상(理想)을 효율적으로 드러내기 위해 당시 보편적으로 쓰이던 도교 관련 어휘들을 원용(援用)한 것이다. 우리민족의 고유사상은 단군신화(檀君神話)와 이를 계승한 신라의 풍류도(風流道)에서 그 근원과 특징을 엿볼 수 있는데, 『동경대전(東經大全)』과 『용담유사(龍潭遺詞)』의 고유사상적 내용을 검토하면 다음과 같은 결론이 도출됨을 개진하였다. 첫째, 동학의 경전에 제시된 ‘천황씨(天皇氏)’는 중국의 신화적 인물이 아니라 단군신화의 ‘환웅(桓雄)’이다. 둘째, 최제우가 실천목표로 삼은 ‘다시개벽’은 환웅의 개벽사상을 계승한 것이다. 셋째, 동학의 주문수련(呪文修鍊)과 검결(劍訣)은 고대로부터 우리 민족이 중시한 가무(歌舞)의 전통을 계승한 것이다. 넷째, 동학은 풍류도의 포함삼교(包含三敎)의 논리 및 접화군생(接化群生)과 친연성을 가진다. This study aims at researching that the ideological foundation of Donghak is not Confucianism, Buddhism and Taoism (Yubuldo), but the indigenous Korean thought. Since the introduction of Yubuldo into Korea during the Three Kingdom period, Confucianism and Buddhism have settled down as traditional Korean thoughts, while the identity of Taoism, mixed with folk-beliefs, was not clear. Since Donghak is Korean people’s religion and academic thoughts, it should be explored in the Korean cultural tradition and historical context. However, Yubuldo cannot be the essence of Donghak. It can be found that our indigenous thought has the origin in the Myth of Dangun and the Pungrudo which inherited it and also holds the features related with them. After reviewing the contents of the indigenous thoughts in Dong-Kyung Dae-jun and Yongdam-yusa, the conclusion I reached is as follows. First, ‘Cheonhwang-ssi’ presented in Donghak Scripture is not a mythical Chinese character but ‘Hwanung’ in the myth of Dangun. Second, ‘Dasigaebyeok the recreation of the world’ at which Choi Je-u aimed in practice succeeded Hwanung’s Gaebyeok thoughts. Third, Jumunsuryeon and Geomga in Donghak succeeded the traditions of song and dance to which Korean people attached importance since ancient times. Fourth, Donghak has an affinity with Pungryudo’s logic of Pohamsamgyo - It includes all three religions, Yubuldo, and Jeobhwagunsaeng - It aims to contact, reform and save all living beings.

생명과학기술, 생명윤리, 그리고 생태학적 관점의 관계 고찰 - 로이스 로리의 『더 기버』를 중심으로

최훈 ( Choi¸ Hoon ),김대영 ( Kim¸ Dae-young ) 동국대학교 영어권문화연구소 2015 영어권문화연구 Vol.8 No.3

The purpose of this study is to examine the relationship between bio-technology and bio-ethics through ecological perspectives and to find examples in literature for the inter-relationships and activating public’s ethical discourse. This study explores complementary relationship between bio-technology and bio-ethics because if our human society ignores bio-technology’s positive fruits due to some faults, it will lack elements of human’s fundamental quality of life as well as the uncertainty of our survival. Therefore, our human society needs various resources to sustain its quality of life through diverse discourses, from different viewpoints such as ethics and literature as well as science-technology. This study tries to explore the relationship between technological effectiveness and biodiversity and to connect them to bio-ethics' possibility based on an ecological perspective. To find the social control's problems of human society, First, this study analyzes biodiversity decreases. Also, it relates biodiversity to the absence of bio-ethic consciousness. With these theoretical basis, this study suggests that Lois Lowry's work, The Giver, exemplifies inter-relationships among bio-technology, bio-ethics, and ecological perspectives. The reason to find this inter-relationship in the literature is that the literary works can easily connect each disciples and interpret each other. In addition, because literature can also have relations with the pubic audience, it can widen some discourses in the public. With this interdisciplinary aspect among bio-tech, bio-ethics, and literature, this study would like to reveal new approaches to a variety of problems in human society, to have some discussion, and to find proper reponses for these problems.

U-Campus에서의 e-Learning 교육 활성화 방안

이대훈 忠州大學校 2007 한국교통대학교 논문집 Vol.42 No.-

This paper contributed to the results as follows; 1) From the U-campus it invested and analysed the necessity of e-learning education. 2) In the e-learning field, it presented the model and it will be able to activate an education. 3) It presented the plan against the activation of e-learning from the U-campus.

Multiple Spinal Intradural Schwannomas Combined with Sequestered Lumbar Disc Herniation

김대용,김진욱,정주호,조재훈 고신대학교 의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

In this report, we describe a case of multiple intradural schwannomas in the spine combined with a upward sequestered disc herniation at L4-L5. It is often difficult to differentiate this tumor from lumbar disc herniation, especially a sequestered hernia. Gadolinium-enhanced MR images were a useful preoperative examination modality for differentiating these lesions from other diseases. Microscopically, the intradural tumors were successfully removed. The dura maters of the L2 and S1 were opened microsurgically, allowing the nerve fibers involved in the tumor to be identified. The involved fibers were cut around the tumor, and the lesion was resected while the intact nerve fibers were preserved. An upward sequestered lumbar disc herniation at L4-L5 was also successfully removed. Based on histological examination of the resected specimen, the tumors were diagnosed as schwannomas. Microsurgery allowed the tumors to be removed with minimal impairment from cutting of nerve fibers in the each nerve root.

Infected Epidermoid Cyst Including Multiple Nails at the Amputated Thumb Stump: A Case Report

김대근,곽병훈 순천향대학교 순천향의학연구소 2021 Journal of Soonchunhyang Medical Science Vol.27 No.2

Fingertip amputation is a common injury among trauma occurring in the upper extremity. After amputation of the fingertip, there are several treatment options according to the degree of damage. Also, the skin flap is sometimes performed when skin defects are accompanied. Among the complications associated with fingertip injury, cyst formation at the amputation stump is rare but some cases have been reported based on the pathologic findings. There was a case of an infected epidermal inclusion cyst containing multiple nail plates at the amputation stump of the thumb, so we would like to report it with a review of the literature.

RT-LAMP를 이용한 콩황화일반모자이크바이러스의 진단

배대현, 이영훈, 김봉섭, 윤영남, 강범규, 최만수, 구성철, 김현태, 윤홍태, 이수헌, 백인열 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

Soybean yellow common mosaic virus (SYCMV) has been recently reported, it has been occurred a lot with Soybean mosaic virus (SMV) and Soybean yellow mottle mosaic virus (SYMMV) in soybean field. SYCMV belongs to genus of Sobemovirus and induced viral symptoms with yellowing, mottle and mosaic. A reverse transcription loop-mediated isothermal amplification (RT-LAMP) method allowed one-step detection of gene amplification by simple procedure and needed only a simple incubator for isothermal template. This RT-LAMP method allowed direct detection of RNA from virus-infected plants without thermal cycling and gel electrophoresis. In this study, we designed RT-LAMP primers named SYCML-F3/B3/FIP/BIP from coat protein gene sequence of SYCMV. After the reaction of RTLAMP, products were identified by electrophoresis and with the detective fluorescent dye, SYBR Green I. under daylight and UV light. Optimal reaction condition was at 63 for 60min and the primers of RTLAMP showed the specificity for only SYCMV tested in this study.

출생후 흰쥐 망막에서 recoverin면역반응 원뿔두극세포의 분화와 GABA성 무축삭세포와의 연접형성 시기

박대균,김인범,천명훈,정진웅 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.1

반도체 제조 공정에서 장비와 호스트간 SECS 프로토콜 개발

이병훈,김대원 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

The SECS(SEMI Equipment Communications Standard ) is a standard pr communication between equipments and a host in semiconductor processes. T proposes the implementation of the HSMS(High-speed SECS Message Services interface for transmission of the SECS messages and SECS-II containing message defined as an SEMI standard. The HSMS driver is implemented as a type of the program and several DLL files. The SECS-II is composed of the SML(SECS Language) file defining the SECS messages, the SML translator to interpret and the SML and the data indx table to refer to SECS messages. We also define the parameters to exchange the HSMS header and SECS message between the HSMS SPECS-II. Eventually, to show the effectiveness of the proposed drivers, we test communications between equipments and a host using the implemented communication programs.

結合係數의 周波數 依存性을 고려한 MCF의 設計에 對한 고찰

李大勳 忠州大學校 1986 한국교통대학교 논문집 Vol.20 No.1

MCF with main electrode and stripe electrode is a filter of ditributed constant group, and has a defect that the distortion of passband characteristic grows with the increase of bandwidth. In this paper we analyzed and examined this problem, and suggested a new way of design for the improvement of ripple. We reckoned 4 electrode MCF by numerical calculation, suppressed ripple less than0.2 dB, and showed that possible bandwidth proportion in design can expand into more than twice.