眼鏡렌즈의 光學的 特性

金大年 대구보건대학 1991 대구보건대학 論文集 Vol.12 No.-

When a beam of tight meets a spectacle lens, only 92% of it is transmitted ; the other 8% is lost by reflection-4% from each of the front and rear surfaces. Now if we add a tranaparent coating to the lens, the same single incident lightwave is partially reflected back in two waves, one from the front surface of the coating, the other from the rear surface. These two waves cancel each other out by destructive, or out of phase interference. By using the vacuum coated antireflecting films, Ophthalmic lenses can greatly reduce the loss of light by reflection on the surface of lenses. Stray light reaching the images as a result of reflection is also greatly eliminated wit a resulting increase of transmittance in contrast. Therefore, ten to one of Ophthalmic lenses are now coated with a single layer of MgF₂, a three layers of MgF₂-ZrQ₂-CeF₂ or MgF₂-ZrO₂-OM-6 to reduce reflection. In this Work, optical properties of vacuum coated thin films of Ophthalmic lenses are investigated. The Optimum thickness of thin film layers are determined by considering the index of refraction of Ophthalmic lenses measured by the Pulfrich refractometer, and the reflectance and transmittance are measured by visible spectrophotometer. The transmittance of multilayer films is higher than that of single layer films. The transrmittance and reflectance of white crown lenses coaxed with MgF₂-ZrO₂-OM-6 is 94% and 0.8% respectively.

대도시 가족의 주거생활역사(Housing History)에 관한 연구(Ⅰ) : 주택소유형태, 주택유형,거주지역, 거주기간을 중심으로 Focused on the Housing Tenure Type, Housing Structure, Residential Areas and Length of Residence

김대년 서원대학교 응용과학연구소 1993 응용과학연구 Vol.2 No.1

The purpose of this study is to investigate the housing history of the families dwelling in Seoul through an analysis of longitudinal data with microsociological perspective. Interviews with a questionnaire were conducted with 451 household wives to collect data. The data were analyzed by ANOVA, Chi-Square Test and Duncan's Multiple Range Test. The major findings were as follows:Percent distribution of acquring the housing tenureship was increasing generally but the changing pattern was very diverse according to the groups classified by marriage year. The housing structure, residential areas and length of residence were also different in the changing patterns and in the individual housing experiences. Therefore the microsociological approach with longitudinal method has to be applied for investigating accurataly the family housing history.

老人療養施設 入住 意思가 있는 韓國 中年層의 老後 展望 및 老人療養施設에 대한 認識과 選好

김대년,권오정 대한건축학회 2005 대한건축학회논문집 Vol.21 No.1

Korea has a rapidly aging population as more and more people are living to an older age Although managing to live In their own homes(aging-in-place) in the most desirable arrangement, there is a need for long-term care facilities to enable elderly people to get social and medical care services Such facilities avoid the high costs of long-term hospitalization for the elderly and provide social services to those without family members to take care of them This study was conducted to clarify the perceptions and preferences of middle-aged Koreans about their outlook on aging and long-term care facilities for the elderly A Survey questionnaire by 1100 adults In their 50s living In different big cities in Korea was used to collect the data The data of 623 of those surveyed who expressed willingness to reside at such facilities If they were very frail was analyzed using SPSS window program The results are as follows, a majority of respondents 1) perceived that the responsibility was theirs for making arrangements for their future care and housing, but thought that the government should make greater efforts to Improve the facilities for the elderly, 2) didn't have negative stereotypes of those facilities, 3) perceived the facilities would provide a systematic care service and should include user-paid medical facilities and that It should be available for middle and high-class elderly, 4) perceived that various kind of facilities should be developed according to the degree or type of disability, length of residence, and the level of service, 5) preferred the facilities to be located in City suburbs first, in cities second, and in the country last, 6) preferred to have personal spaces of 11-20 pyung and to have public spaces primarily for sports and other recreational activities The education level of respondents or their spouses, average monthly Income and property Status were major variable's which showed significant differences in the perceptions and preferences of middle-aged Koreans willing to reside at long-term care facilities The results of this study provides reliable information for the development of long-term care facilities In the near future

국내 가사노동 연구의 동향 분석 (I) : 생활시간, 태도 및 만족도, 가사분담 연구를 중심으로 with focus on the literatures of the time studies, the attiudes toward and satisfaction with household tasks, and the division of household tasks

김대년,이연숙 카톨릭 대학교 생활과학 연구소 1990 생활과학연구논집 Vol.10 No.1

The purposes of this study are to analyze the trends of household task studies and to identify the common variables affecting each topic. The results of review of the literature were as follows: ①The variables affecting the attitudes toward, value perception about and satisfaction with the household tasks were the education level and age of wife, income, employment status of wife, and length of marriage. The psychological factors were found to be the variables affecting the level of satisfaction with household tasks. ②The age of children, employment status of wife, income, and the presense of house keeper were found to be as factors affecting the amount of time spenton household tasks. ③Compared with other studies, the variables affecting the aspects of household task division were found not to differ among studies. The impacting variables were the employment status of wife, the age of wife, socio-economic status of the family, structure of house, and income.

재원기간중 사망한 급성 심근경색증 환자의 임상적 특징

현대우,김기식,신이철,박소영,배장호,한창엽,김윤년,김권배 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.9

상심실성 빈맥환자에서 관상정맥동의 형태비교

현대우,김윤년,박소영,한성욱,허승호,김기식,김권배 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.4

주의력결핍과잉행동장애와 Alpha-1C-Adrenergic 수용체 유전자와의 연관성에 대한 연구

조수철,김재원,김붕년,황준원,박미라,김순애,조대연,유희정,정운선,손정우,박태원 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : Neurobiological and pharmacological research has suggested that the dysregulation of the central noradrenergic systems might be involved in the pathophysiology of ADHD. The aim of this study was to examine the association of the alpha-1C-adrenergic receptor gene (ADRA1C) with ADHD in Korean subjects. Methods : In a case-control study, we assessed 186 DSM-IV ADHD probands and 150 normal controls. One hundred and eight trios were studied in a family-based association analysis. Psychiatric diagnoses were derived through structured diagnostic interviews. For the clinical evaluation of the ADHD subjects, the Child Behavior Checklist (CBCL), the ADHD Rating Scale-IV (ARS) and the Junior Temperament and Character Inventory (JTCI) were administered. A computerized continuous performance test (CPT) was used to measure the inattention and impulsivity of the ADHD children. Results : There were no significant differences in the genotype or allele frequencies of the ADRA1C PstI polymorphism between the ADHD and control group (p>0.05). The transmission disequilibrium test (TDT) analysis observed no evidence for biased transmission of any of the alleles of the PstI polymorphism. There were no significant differences in the CPT or JTCI profiles between those ADHD subjects with the CC genotype and those with the other (CT+TT) genotypes at the PstI polymorphism. Conclusion : The results of this study do not support the ADRA1C as a major genetic susceptibility factor in ADHD.

Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments

Kim, Hye-Jin,Kwon, Sojung,Nam, Seo Hee,Jung, Jae Woo,Kang, Minkyung,Ryu, Jihye,Kim, Ji Eon,Cheong, Jin-Gyu,Cho, Chang Yun,Kim, Somi,Song, Dae-Geun,Kim, Yong-Nyun,Kim, Tai Young,Jung, Min-Kyo,Lee, Kyun The Federation of American Societies for Experimen 2017 The FASEB Journal Vol.31 No.4

<P>Membrane proteins sense extracellular cues and transduce intracellular signaling to coordinate directionality and speed during cellular migration. They are often localized to specific regions, as with lipid rafts or tetraspanin-enriched microdomains; however, the dynamic interactions of tetraspanins with diverse receptors within tetraspanin-enriched microdomains on cellular surfaces remain largely unexplored. Here, we investigated effects of tetraspan(in) TM4SF5 (transmembrane 4 L6 family member 5)-enriched microdomains (T5ERMs) on the directionality of cell migration. Physical association of TM4SF5 with epidermal growth factor receptor (EGFR) and integrin alpha 5 was visualized by live fluorescence cross-correlation spectroscopy and higher-resolution microscopy at the leading edge of migratory cells, presumably forming TM4SF5-enriched microdomains. Whereas TM4SF5 and EGFR colocalized at themigrating leading region more than at the rear, TM4SF5 and integrin a5 colocalized evenly throughout cells. Cholesterol depletion and disruption in TM4SF5 post-translational modifications, including N-glycosylation and palmitoylation, altered TM4SF5 interactions and cellular localization, which led to less cellular migration speed and directionality in 2-or 3-dimensional conditions. TM4SF5 controlled directional cell migration and invasion, and importantly, these TM4SF5 functions were dependent on cholesterol, TM4SF5 post-translational modifications, and EGFR and integrin alpha 5 activity. Altogether, we showed that TM4SF5 dynamically interacted with EGFR and integrin a5 in migratory cells to control directionality and invasion.-Kim, H.-J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J.-G., Cho, C. Y., Kim, S., Song, D.-G., Kim, Y.-N., Kim, T. Y., Jung, M.-K., Lee, K.-M., Pack, C.-G., Lee, J. W. Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2-and 3-dimensional environments. FASEB J. 31, 1461-1481 (2017). www.fasebj.org</P>

Preparation of protein microarrays on non-fouling and hydrated poly(ethylene glycol) hydrogel substrates using photochemical surface modification

Kim, Dae-Nyun,Lee, Woojin,Koh, Won-Gun John Wiley Sons, Ltd. 2009 Journal of chemical technology and biotechnology Vol.84 No.2

<P>BACKGROUND: Conventional protein microarrays prepared on hard, dry substrates, such as glass and silicone, have several limitations, as proteins may easily denature and lose their structure. To overcome such problems, the fabrication of wet protein microarrays on non-fouling and hydrated PEG-based hydrogels was investigated.</P><P>RESULT: Bovine serum albumin (BSA) and glucose oxidase (GOX), chosen as model proteins, were covalently immobilized on PEG hydrogel surfaces via 5-azidonitrobenzoyloxy N-hydroxysuccinimide, a photoreactive bifunctional linker. Successful fixation of the bifunctional linker and subsequent immobilization of the proteins on the PEG hydrogel surfaces were confirmed with X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR) studies. GOX immobilized on the hydrogel surface maintained approximately 50% of its initial activity after 24 h when left in dry conditions, but maintained only 20% when immobilized on a dry substrate. Photochemical fixation combined with photolithography produced well-defined protein micropatterns with sizes ranging from 50–500 µm, and molecular recognition-mediated specific binding between biotin and streptavidin was successfully assayed using microarrays on PEG hydrogels.</P><P>CONCLUSION: A protein-repellent PEG hydrogel surface was photochemically modified to covalently immobilize proteins and create protein microarrays. The use of hydrated hydrogels as substrates for protein microarrays could minimize the deactivation of proteins in dry conditions, and the non-fouling property of PEG hydrogels allows the passivation step of protein microarray preparation to be skipped. Copyright © 2008 Society of Chemical Industry</P>

Electrospun Poly(ethylene glycol) Hydrogel Nanofibers

Dae Nyun Kim,Hyun Jong Lee,Woojin Lee,Yeol Lee,Eun Ji Jang,Sang Phil Park,Saemi Park,Wongun Koh 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.4