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정시안에서 연령에 따른 전체난시, 각막난시, 잔여난시의 분포변화
김찬수, 류정완, 김현승, 이영춘Chan-Soo Kim M.D. Jung-Wan Ryu M.D. Hyun-Seung Kim M.D. Young-Chun Lee M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.3
Purpose: We evaluated the distribution and change of total, corneal and residual astigmatism with age in patients with emmetropia. Methods: We examined the visual acuity, refraction, and corneal curvature in 263 persons aged from 3 to 83 years (mean, 38 years), with a spherical equivalent refraction of under ±0.75 diopter (D). We analysed the distribution and change of the astigmatism. Results: Total astigmatism was changed from with-the-rule (WTR) to against-the-rule (ATR) with aging based on WTR of 0.31±0.48 D in the 3-10 year-old group, ATR of 0.02 ±0.52 D in the 31-40 year-old group and ATR of 0.65±0.66 D in the 71-83 year-old group. Corneal astigmatism showed a similar pattern to that of total astigmatism with WTR of 1.03±0.47 D, WTR of 0.37±0.78 D, ATR of 0.05±0.59 D and ATR of 0.31±0.64 D in the 3-10, 31-40, 61-70 and 71-83 year-old groups, respectively. Residual astigmatism showed ATR astigmatism in all age groups such as ATR of 0.71±0.48 D, ATR of 0.60±0.44 D and ATR of 0.35±0.71 D in the 3-10, 41-50 and 71-83 year-old groups, respectively. Conclusions: Total and corneal astigmatism showed the change from WTR to ATR, and residual astigmatism showed the pattern of decreasing ATR with aging in patients with emmetropia. The change of total astigmatism with aging seems to be influenced by that of corneal astigmatism rather than by that of residual astigmatism.
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김완두(W. D. Kim),우창수(C. S. Woo),이학주(H. J. Lee),정승일(S. I. Jung),김석원(S. W. Kim),김영구(Y. K. Kim),최경진(K. J. Choi),이동형(D. H. Lee) 한국철도학회 2000 한국철도학회 학술발표대회논문집 Vol.- No.-
An air spring was accepted for rail vehicle secondary suspension to reduce and absorb the vibration and the noise. The air spring for the electric railway was developed with domestic technology, which consisted of a cord reinforced rubber bellows, a upper plate, a lower plate and a stopper rubber spring. The fatigue test was conducted in laboratory by using servo hydraulic fatigue testing system to verify the durability. And to guarantee the adaptation of this air spring, the ride comfort and the air pressure variation were measured in train test on Boondang line.
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결막 평편상피 유두종 환자에서 점안 인터페론의 치료 효과
김주엽, 김윤덕Ju Yeob Kim M.D. Yoon Duck Kim M.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.11
Purpose: To study the effectiveness of Interferon alfa-2b (IFNα2b) for treating squamous papilloma of the conjunctiva. Methods: One million units/cc of IFNα2b was applied 4 times a day after identifying squamous papilloma by excisional biopsy. The IFNα2b was used continuously 2 to 6 months after the tumor became undetectable with the unaided eye. The dose was then tapered. Results: Three of the 4 patients had a history of recurrences (1-4 times). In one patient, the tumor was difficult to remove surgically due to the location of the tumor (around the upper punctum). The tumor disappeared with no complications or recurrences during the follow-up period. Conclusions: In patients with conjunctival squamous papilloma with frequent relapses or difficulty in excision, applying IFNα2b as an eye drop appears to be an effective form of therapy and can be used safely without complications.
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사람 망막아세포종 세포에 발현된 니코틴성 수용체의 특성
김대란, 차승규, 공인덕, 정세환, 라상훈Dae-Ran Kim Ph.D. Seung-Kyu Cha Ph.D. In-Deok Kong M.D. Se-Hwan Jung M.D. Sang Hoon Rah M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.6
Purpose: To identify the characteristics and physiological function of the nicotinic receptor expressed in human retinoblastoma cells. Methods: We measured possible nicotinic signaling in WERI-Rb-1 cells using the Ca2+ imaging technique and the patch clamp method. Results: 1) Nicotine-induced [Ca2+]i rise arose entirely through Ca2+ influx, which was completely abolished by hexamethonium (100 μM). 2) Nicotine also induced remarkable depolarization from -56.6±3.7 mV to -29.6±3.6 mV (n=4) under current clamp mode, but it failed to directly activate the T-type Ca2+ channel expressed in retinoblastoma cells. Conclusions: Nicotinic activation can increase the intracellular calcium level through calcium influx in the undifferentiated retinoblastoma cells, which may play important roles in cell proliferation, differentiation, and cell death.
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가토에서 트리암시놀론 유리체내 주사가 국소 망막박리에 미치는 영향
김무연, 이영춘, 박영훈Muyan Kim M.D. Young-Chun Lee M.D. Young-Hoon Park M.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.4
Purpose: To investigate the effect of localized retinal detachment on both the detached and attached regions, and to determine the effect of triamcinolone on Müller cell gliosis. Methods: Pars plana vitrectomy was performed in both eyes of 12 pigmented rabbits. A dome‐shaped retinal detachment was made by injecting sodium hyaluronate into the subretinal space. Triamcinolone (5 mg) was applied intravitreally to one eye (12 eyes). The detached retinal area and the neighboring attached region were studied by light and electron microscopy 3, 7, and 28 days after surgery. Tissues were prepared in 5 um sections for hematoxylin-eosin staining and immunohistochemistry with antibody to glial fibrillary acidic protein (GFAP). Results: In addition to the well-known degeneration of photoreceptor cells in the detached retina, an incomplete but severe loss of ganglion cell axons occurs in both the detached and the attached regions. The total retinal thickness gradually decreased in the detached areas, while the thickness of the inner retinal layers remained virtually unchanged over several weeks. Gliotic alterations were apparent in both the detached and non-detached retinal areas, and intravitreal triamcinolone did not alter these gliotic alterations of Müller cells. Conclusions: It is noteworthy that progressive retinal destruction also occurs in the attached retina after local detachment. This may account for visual impairment in strikingly large areas of the visual field, even after retinal reattachment.
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김가정,송유정,문형곤,정상호,정치영,주영태,정은정,이영준,최상경,하우송,박순태,홍순찬,Ka-Jeong Kim,M,D,Yu-Jeong Song,M,D,Hyung-Gon Moon,M,D,Sang-Ho Jeong,M,D,Chi-Young Jeong,M,D,Young-Tae Ju,M,D,Eun-Jung Jung,M,D,Young-Joon Lee,M,D,Sang-K 대한갑상선-내분비외과학회 2009 The Koreran journal of Endocrine Surgery Vol.9 No.1
Adrenal cysts are a relatively uncommon disorder and most such cases are discovered at autopsy. According to the overseas cases, the reported incidence is 0.06∼0.18% and the incidence is increasing due to the widespread use of ultrasonography and computed tomography scanning. Adrenal cysts are usually asymptomatic and they need to be differentiated from other cystic lesions including liver, pancreas and kidney cystic lesions. We report here on a case of a 39-year-old female with an adrenal pseudocyst that was misdiagnosed preoperatively as a pancreas mucinous cystic neoplasm. (Korean J Endocrine Surg 2009;9: 30-32)
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