ON THE ROBUSTNESS OF FORWARD MARKET EFFICIENCY IN CONSUMPTION - BASED MODELS OF EXCHANGE RATES

ARROYO Ⅲ, CRISTINO R. 한국국제경제학회 1994 International Economic Journal Vol.8 No.2

Euler equation models with consumption risk premia have shown promise of reconciling exchange rate data with the hypothesis of efficiency of the forward exchange rate. We examine the robustness of these models to variation in (1) the period utility function, (2) assumptions about the underlying forward trading mechanism, (3) the measure of consumption in the risk premium and (4) the weighting matrix applied to the model orthogonality conditions. In generalized method of moments estimations using a six-currency sample we find evidence that forward efficiency is robust to perturbations of the first two kinds, but not to the latter two. [F31, G14]

Integration of Forming Operations on Hybrid Additive Manufacturing Systems Based on Fusion Welding

João P. M. Pragana,Valentino A. M. Cristino,Ivo M. F. Bragança,Carlos M. A. Silva,Paulo A. F. Martins 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.7 No.3

This paper is focused on the integration of metal forming operations in hybrid systems that combine additive manufacturing (AM) by gas metal wire arc and subtractive manufacturing by machining. The investigation is carried out in AISI 316L stainless steel wire and draws from tensile testing to incremental sheet forming of truncated conical shapes. Commercial sheets from the same material are utilized for comparison purposes. Thickness measurements, digital image correlation (DIC), circle grid analysis (CGA) and microstructural and scanning electron microscopy (SEM) observations are carried out to understand how diff erent is the mechanical behaviour of the deposited metal from that of commercial metal sheets and how signifi cant is the infl uence of the deposited metal microstructure on its overall formability. Results confi rm that integration of metal forming operations in hybrid AM routes is feasible despite the formability of deposited metal being smaller than that of the commercial metal sheets due to the strong anisotropy induced by the dendritic based microstructure of the deposited metal. Incremental forming of two deposited parts also allows concluding that integration of metal forming operations in hybrid AM systems is a step towards green and sustainable manufacturing by extending their fi eld of applicability to the fabrication of complex ready-to-use parts requiring combination of diff erent processes.

The Effects of Supplementing Methionine plus Cystine to a Low-protein Diet on the Growth Performance and Fat Accumulation of Growing Broiler Chicks

Bunchasak, C.,Satoso, U.,Tanaka, K.,Ohtani, S.,Collado, Cristino M. Asian Australasian Association of Animal Productio 1997 Animal Bioscience Vol.10 No.2

This experiment was conducted to determine the effects of a low-protein diet supplemented with DL-methionine plus L-cystine (Met + Cys) on the growth performance and fat accumulation of female broiler chicks during the growing period (3-6 wks old). A low-protein diet (17% CP; 3,200 ME kcal/kg) was supplemented with Met + Cys (1.1 : 1.0) at levels 0.75, 0.94, 1.25, 1.31 or 1.50% of diet, respectively. Another diet with 21% CP and 3,200 ME kcal/kg served as the control group. All essential amino acids were adjusted to meet the National Research Council (1984) requirement for chicks. Feed and water were given ad libitum. Body weight of the chicks fed the low-CP diets supplemented with Met + Cys were heavier than those of the control birds. Feed conversion ratio and feed intakes were not significantly different between and among the treatment groups. Similary, abdominal fat content was not significantly different among the various treatments except that of the chicks fed the low CP diet with 1.25% Met + Cys which was higher than that of the control group. Fatty acid synthetase (FAS), acetyl-CoA carboxylase (ACC) activities and carcass protein content were not influenced by dietary treatments. Carcass fat content was lowest in chicks fed low CP diet with 0.75% Met + Cys and highest in the group that received 1.50% Met + Cys supplementation. Liver triglyceride increased as Met + Cys supplementation level increased. Various lipid fraction concentrations (cholesterol ester, free cholesterol, and phospholipid) in the serum went up as Met + Cys increased up to 1.25% after which it levelled off. Results of this experiment suggest that it is possible to reduce dietary protein level from 21% to 17% for growing broiler chicks by the supplementation of Met + Cys when other EAA were sufficient.

Effect of Euterpe oleracea Mart. Seeds Extract on Chronic Ischemic Renal Injury in Renovascular Hypertensive Rats

Cristiane Aguiar da Costa,Dayane Teixeira Ognibene,Viviane Silva Cristino Cordeiro,Graziele Freitas de Bem,Izabelle Barcellos Santos,Ricardo Andrade Soares,Letı´cia L. de Melo Cunha,Lenize C. R.M. Car 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.10

Previously, we have demonstrated that the seeds of Euterpe oleracia Mart. (açaí) are rich in polyphenols with antihypertensive and antioxidant properties. This study evaluated the renal protective effects of the hydroalcoholic extract obtained from the seeds of açaí (ASE) fruits in two-kidney, one-clip (2K1C) renovascular hypertension. Young male Wistar rats were used to obtain 2K1C and sham groups. Animals received ASE (200 mg/(kg·day) in drinking water) or vehicle for 40 days. We evaluated serum and urinary parameters, renal structural changes, and oxidative status. The increase in systolic blood pressure of the 2K1C group was accompanied by a decrease in left kidney volume and number of glomeruli, as well as an increase in glomerular volume and collagen deposition. ASE prevented the alterations of these parameters, except the reduced kidney volume. Serum levels of urea and creatinine and urinary protein excretion were increased in the 2K1C group and treatment with ASE improved all these functional parameters. The increased oxidative damage in the 2K1C group, assessed by lipid and protein oxidation, was prevented by ASE. The nitrite content and both expression and activity of antioxidant enzymes (superoxide dismutase-1, catalase, and glutathione peroxidase) were lower in the 2K1C group and restored by ASE. ASE substantially reduced renal injury and prevented renal dysfunction in 2K1C rats probably through its antihypertensive and antioxidant effects, providing a natural resource for treatment and prevention of renovascular hypertension-related abnormalities.

Garlic Powder Ameliorates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

Ana Carolina Razo-Rodríguez,Yolanda I. Chirino,Dolores Javier Sánchez-González,Claudia María Martínez-Martínez,Cristino Cruz,José Pedraza-Chaverri 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.3

cis-Diamminedichloroplatinum (II) (cisplatin) is an effective chemotherapeutic agent successfully used in the treatment of a wide range of tumors. Nevertheless, nephrotoxicity has restricted its clinical use. The use of more than a few antioxidants has shown that reactive oxygen species are involved in cisplatin-induced nephrotoxicity. In the present work the effect of garlic powder, a recognized antioxidant, on cisplatin-induced nephrotoxicity and oxidative and nitrosative stress was studied. Rats were fed with a 2% garlic powder diet for 4 weeks. A single injection of cisplatin (7.5 mg/kg) induced tubular damage and an increase in the following markers of renal injury 3 days later: blood urea nitrogen, serum creatinine, and urinary excretion of N-acetyl-β-D-glucosaminidase. The cisplatin injection also increased 3-nitrotyrosine and 4-hydroxy-2-nonenal immunostaining in renal cortex and medulla. It was found that the garlic powder feeding was able to prevent by 40–59% the alterations in the markers of renal injury studied, by 33% the histological damage, and by 38–75% the increase in markers of oxidative and nitrosative stress. It is concluded that the ability of garlic powder to ameliorate cisplatin-induced renal injury is associated with its antioxidant properties. Our data support the use of garlic powder as a renoprotective agent.

Vitis vinifera L. Grape Skin Extract Prevents Development of Hypertension and Altered Lipid Profile in Spontaneously Hypertensive Rats: Role of Oxidative Stress.

Giselle Franca da Costa,Dayane Teixeira Ognibene,Cristiane Aguiar da Costa,Michelle Teixeira Teixeira,Viviane da Silva Cristino Cord,Graziele Freitas de Bem,Anibal Sanchez Moura,Angela de Castro Resen 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.1

This study investigated the protective effect of a Vitis vinifera L. grape skin extract (ACH09) on blood pressure, lipid profile, and oxidative status in spontaneously hypertensive rats (SHR). Systolic blood pressure (SBP), total cholesterol, triglyceride, and glucose levels, as well as oxidative damage and antioxidant activity in the plasma and kidney, were evaluated in four experimental groups: control Wistar rats (W-C) and SHR-C that received water, and Wistar rats and SHR treated with ACH09 (200 mg/kg/d) in drinking water for 12 weeks (W-ACH09 and SHR-ACH09, respectively). SBP increased in the SHR group compared with the W groups and the treatment with ACH09 prevented the development of hypertension. Plasma triglyceride and total cholesterol levels increased in SHR compared with W-C rats; these changes prevented by treatment with ACH09. Glucose levels did not differ between the groups. The SHR group had increased oxidative damage in plasma, as expressed by 2-thiobarbituric acid reactive substances (TBARS) levels, and this prevented by ACH09. Levels of TBARS in the kidneys were lower in the SHR-ACH09 group than in the SHR-C group. Further, ACH09 increased the superoxide dismutase activity in both the plasma and kidneys of both SHR and Wistar rats. These results suggest that ACH09 is protective against disruption of blood pressures, oxidant status, and lipid profile in SHR, and provide important evidence on the benefits of ACH09 on hypertension and associated cardiovascular complications.