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Congo Tak Shing Ching,Pei-Yuan Lee,Nguyen Van Hieu,Hsin-Hung Chou,Fiona Yan-Dong Yao,Cheng Sha-Yen,Lin Yung-Kai,Thien Luan Phan 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.3
Microplastic, being a direct carrier of many pollutants, has caused grave concern and become a public issue. This gives rise to the need of a quick method for quantifying and identifying microplastics in the environment. This study uses impedance spectroscopy, particularly the imaginary part of impedance, for detection and identification of sample microplastics. Two type of common microplastic contaminants, Polyethylene and Polystyrene, diameter 20 m and 150 m, were chosen for this study. The results confirm accurate identification of microplastic material in question, by using self-normalized ratio between two characteristic frequencies of 7MHz and 8.9 MHz, Zf = 7 MHz / Zf = 8.9 MHz. 3-kNN classifier built with the ratio Zf = 7 MHz / Zf = 8.9 MHz, and Zf = 8 MHz /Zf = 8.9 MHz, demonstrates accuracy upto 90% for the identification of single or both microplastic types in samples. These results confirm impedance spectroscopy, permitting rapid identification of microplastic without labeling and skillful techniques, as a potential rapid sensor.
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Rui Azevedo Guerreiro,Paula Fazendas,Ana Rita Pereira,Ana Marques,João Pais,Sofia Alegria,Kisa Hyde Congo,Ana Catarina Gomes,João Carvalho,Gonçalo Morgado,Inês Cruz,Ana Rita Almeida,Isabel João,Hélder 한국심초음파학회 2020 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.28 No.2
BACKGROUND: Stress echocardiography has a 72%–85% sensitivity and an 80%–95% specificity. In this study, we characterized patients who received a false-positive stress echocardiogram result. METHODS: A total of 5,256 patients underwent a stress echocardiogram (induced by exercise, dobutamine, or dipyridamole) between 2009 to 2018, and 405 patients (7.7%) received a positive result. Among the positive patients, 300 underwent coronary angiography within 12 months, and these patients were included in this study (mean age = 64.9 ± 9.4 years, 230 men [76.7%]). Coronary artery disease was diagnosed by stenosis ≥50% in any epicardial coronary artery. Clinical and echocardiographic variables were compared between patients with true- and false-positive stress echocardiogram results. RESULTS: Seventy-two patients (24%) had a false-positive stress echocardiogram, with similar rates across stressor types (p = 0.574). Patients with false positives were less frequently men (63.9% vs. 80.7%, p = 0.003), had lower diabetes mellitus prevalence (15.3% vs. 45.6%, p = 0.001), were similar to true positive patients with regard to body-mass index, arterial hypertension prevalence, hyperlipidemia and smoking, and had lower pre-test probability of coronary artery disease (23% vs. 32%, p = 0.016). The wall motion score index (WMSI) was higher in the true-positive stress group, and wall motion abnormalities were more frequent in the apical segments (70.5% vs. 56.7%, p = 0.034). In a multivariable predictive model, men (odds ratio [OR] = 2.994), diabetes (OR = 5.440), and peak WMSI (OR = 10.690) were associated with a true-positive result. CONCLUSIONS: Twenty-four percent of our study population received a false-positive stress echocardiogram result, with similar rates across stressor types. Patients with true-positive stress echocardiogram results are more likely to be men, diabetic, and have a high peak WMSI.
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