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Chemical constituents from Inula wissmanniana and their anti-inflammatory activities
Chunhui Wang,Xufeng Zhang,Panlei Wei,Xiangrong Cheng,Jie Ren,Shi Kai Yan,Wei Dong Zhang,Hui Zi Jin 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.12
Two new inositol derivatives, 4-acetate-1,2,3,5-tetrakis(2-methyl-2-butenoate) inositol (1) and 3-acetate-1,2,4,5-tetrakis(2-methyl-2-butenoate) inositol (2), onenew flavonolignan 23-o-acetylsilychristin A (3), and onenew thymol derivative 3-hydroxy-4-(2-hydroxy-1-methylethyl)benzoic acid (4), along with 13 known compounds,including ten flavonolignans (5–14) and three thymolderivatives (15–17) were isolated from the aerial part ofInula wissmanniana. The structures of new compoundswere elucidated by detailed spectroscopic analysis,including HRESIMS and 2D-NMR spectroscopic data. Allthe compounds were isolated from this plant for the firsttime. The anti-inflammatory activities of the compoundswere tested against LPS-induced NO production in RAW264.7 macrophages.
Chunhui Zhao,Kunbing Ouyang,Nian-Fa Yang,Jin Zhang,Zhu Sheng Yang 한국고분자학회 2016 Macromolecular Research Vol.24 No.5
Six optically active oxide propane monomers (1m-6m) were synthesized in a very facile way. The monomers were polymerized using potassium hydroxide (KOH) as an initiator to afford the corresponding polyethers (1p-6p). The polyether (R)-1p (specific rotation, [α]=+331) exhibited optical rotation as large as fourfold that of the monomer (R)-1m ([α]=-10). The specific optical rotation, circular dichroism (CD) and ultraviolet (UV)-visible spectra data showed that the obtained polymers can keep a prevailing helicity of the backbone in solution.
Chunhui Tan,Juhui Sa,Feipeng Cai,Bo Jiang,Gai Yang,Bo Wang,Jinhua Gao,Hua Chen,Xianzhong Qin 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.2
PtRu nanoparticles (NPs) supported on acid treated multiwall carbon nanotubes (Pt1Ru1/ MWCNTs) were prepared by a modified polyol method without adding any other surfactant or protective agent. The structural and compositional properties of the as-obtained samples were characterized by transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), X-ray diffraction (XRD) and X-ray photoelectron (XPS) spectroscopy. The electrocatalytic performance of the catalyst was evaluated by cyclic voltammetry (CV), CO stripping voltammetry and chronoamperometry, indicating a high catalytic activity, excellent CO tolerance and stability for methanol oxidation. Interestingly, a series of accurate controllable experiments have been designed to explore the enhancement mechanism of Pt1Ru1/MWCNTs for methanol oxidation reaction. Most importantly, Pt1Ru1/MWCNTs composites were used as an anode catalyst in the direct methanol fuel cells (DMFCs) exhibiting outstanding power density (126.1 mW/cm2) 1.7 times higher than that of the commercial catalyst of Pt1Ru1/C (74.1 mW/cm2Þ)(E-TEK).
Estimation of Process Damping Coefficient Using Dynamic Cutting Force Model
Chunhui Chung,Minh-Quang Tran,Meng-Kun Liu 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.4
A model of process damping in milling was developed in this study. The process damping is a critical parameter to increasethe stable cutting region at low cutting speed to avoid chatter. The previous studies conducted experiments to estimate theprocess damping. Nevertheless, it is time and cost consuming. A model of dynamic cutting force was employed in this study. The plowing force generated by the fl ank-wave contact is considered as the main source of process damping to dissipatevibratory energy during cutting. In addition to the material properties and plowing force, the eff ects of chatter amplitudeand wavelength, which result in the various indentation conditions and aff ect the coeffi cient of process damping, were alsoconsidered. The consideration of wavy contact surface and indentation area in this model allows quick determination of cuttingstability conditions with high accuracy. The process damping coeffi cient estimated by the proposed model successfullyrepresented the eff ect of the tool wear on chatter because of the change of tool geometry. Experiments were conducted toverify the new model.
Interval valued (∈, ∈∨q)-fuzzy filters in MTL-algebras
Chunhui Liu 원광대학교 기초자연과학연구소 2017 ANNALS OF FUZZY MATHEMATICS AND INFORMATICS Vol.13 No.6
In the present paper, the interval valued (∈, ∈∨q)-fuzzy filter theory in MTL-algebras is further studied. Some new concepts of interval valued (∈, ∈∨q)-fuzzy prime, ultra, regular, strong and divisible filters are introduced and their properties and equivalent characterizations are investigated. Relationships among the above new concepts and interval valued (∈, ∈∨q)-fuzzy Boolean, MV- and G-filters are discussed. It is proved that an interval valued (∈, ∈∨q)-fuzzy filter is an interval valued (∈, ∈∨q)-fuzzy MV-filter if and only if it is both an interval valued (∈, ∈∨q)-fuzzy regular filter and an interval valued (∈, ∈∨q)-fuzzy divisible filter.
Chunhui Cui,Duanyang Zhai,Lianxu Cai,Qiaobin Duan,Lang Xie,Jinlong Yu 대한암학회 2018 Cancer Research and Treatment Vol.50 No.3
Purpose Studies have found that long noncoding RNA HEIH (lncRNA-HEIH) is upregulated and facilitates hepatocellular carcinoma tumor growth. However, its clinical significances, roles, and action mechanism in colorectal cancer (CRC) remains unidentified. Materials and Methods lncRNA-HEIH expression in CRC tissues and cell lines was measured by quantitative realtime polymerase chain reaction. Cell Counting Kit-8, ethynyl deoxyuridine incorporation assay, terminal deoxynucleotidyl transferase dUTP nick end labeling staining, and nude mice xenografts assays were performed to investigate the roles of lncRNA-HEIH. RNA pull-down, RNA immunoprecipitation, chromatin immunoprecipitation, and luciferase reporter assays were performed to investigate the action mechanisms of lncRNA-HEIH. Results In this study, we found that lncRNA-HEIH is significantly increased in CRC tissues and cell lines. lncRNA-HEIH expression is positively associated with tumor size, invasion depth, and poor prognosis of CRC patients. Enhanced expression of lncRNA-HEIH promotes CRC cell proliferation and decreases apoptosis in vitro, and promotes CRC tumor growth in vivo. Whereas knockdown of lncRNA-HEIH inhibits CRC cell proliferation and induces apoptosis in vitro, and suppresses CRC tumor growth in vivo. Mechanistically, lncRNA-HEIH physically binds to miR-939. The interaction between lncRNA-HEIH and miR-939 damages the binding between miR-939 and nuclear factor B (NF-B), increases the binding of NF-B to Bcl-xL promoter, and promotes the transcription and expression of Bcl-xL. Moreover, Bcl-xL expression is positively associated with lncRNA-HEIH in CRC tissues. Blocking the interaction between lncRNA-HEIH and miR-939 abolishes the effects of lncRNA-HEIH on CRC tumorigenesis. Conclusion This study demonstrated that lncRNA-HEIH promotes CRC tumorigenesis through counteracting miR-939mediated transcriptional repression of Bcl-xL, and suggested that lncRNAHEIH may serve as a prognostic biomarker and therapeutic target for CRC.
Variations of the stress intensity factors for a planar crack parallel to a bimaterial interface
Chunhui Xu,Taiyan Qin,Li Yuan,Nao-Aki Noda 국제구조공학회 2008 Structural Engineering and Mechanics, An Int'l Jou Vol.30 No.3
Stress intensity factors for a planar crack parallel to a bimaterial interface are considered. The formulation leads to a system of hypersingular integral equations whose unknowns are three modes of crack opening displacements. In the numerical analysis, the unknown displacement discontinuities are approximated by the products of the fundamental density functions and polynomials. The numerical results show that the present method yields smooth variations of stress intensity factors along the crack front accurately. The mixed mode stress intensity factors are indicated in tables and figures with varying the shape of crack, distance from the interface, and elastic constants. It is found that the maximum stress intensity factors normalized by root area are always insensitive to the crack aspect ratio. They are given in a form of formula useful for engineering applications.