Water-soluble Genistin Glycoside Isoflavones Upregulate Antioxidant Metallothionein Expression and Scavenge Free Radicals

Chung, Mi-Ja,Kang, Ah-Young,Jun, Hee-Jin,Kim Sang-Yeon,Moon, Tae-Hwa,Park, Kwan-Hwa,Lee, Sung-Joon 생명자원연구 2005 생명자원연구 Vol.13 No.-

학교 식중독 예방대책

승정자 韓國學校保健學會 2001 韓國學校保健學會誌 Vol.14 No.1

일부 여대생의 스트레스와 철분 영양상태에 관한 연구

승정자,하보경,김미현,최선혜 숙명여자대학교 건강. 생활과학연구소 1999 生活科學硏究誌 Vol.14 No.1

The purpose of this study was to evaluate the iron status of 39 female adult who divided into five groups according to the stress condition. The iron status was evaluated based on dietary intake and blood analysis. The average age of the subjects was 23.10years, and the average score of BMI was 20.06kg/m2. The proportion of subjects in each stress condition was : 2.56%(1) in A1type(the group who easily get disease associated with stress), 64.10%(25) in A2type(condition susceptible to the disease associated with stress), 30.77%(12) in ABtype(middle type of A and B), 2.56%(1) in B2type(appropriate stressed condition) and 0%(0) in B1type(risk free to the disease associated with stress). The average daily intake of energy in study subjects was 2,399kcal, ti caloric ratio of carbohydrate, protein, fat was 59.90 : 14.39 : 25.71, respectively. There was no significant difference in anthropometric measurements, dietary intake status, hematologic indices of iron status between high stress group(A1type and A2type) and low stress group(ABtype and B2type). To compare the iron stores between high stress group and low stress group, subjects in each group were devided into iron 0 mg, 250 mg, 500 mg group. Stress level did not affect iron stores although in both groups, number of subjects in iron 0 mg group were higher than those of iron 250 mg and 500mg groups. Correlation coefficients between anthropometric measurements, nutrient intake status, hematologic indices of iron status and stress score of subjects did not reveal any significance. Therefore, the results suggest that psychological stress did not affect the iron status in normal female adult. However, be more systematic study on stress and the iron status is required in the future.

都市地域住民의 生活體育 意識構造

鄭相澤,吳東燮,安禹洪,金正子,林銖遠 慶北大學校 體育科學硏究所 1991 체육과학연구지 Vol.7 No.-

This study was aimed to elucidata Taegu citizens' consciousness about Sport for All. 950 subjects responded to the researcher's questionnaires. The results are as follows; 1) 88.8% of whole subjects felt necessity of physical activity in every day life. In view of sex, 91.0% of male and 86.5% of female felt the necessity. 2) 73.4% of the subjects put weight in health improvement and 19.1% of the subjects put weight in strong mental power in relation to the value of physical activity. 3) About the local facilities of physical activity, only 8.3% of the subjects satisfied. A largy majority(65.7%) of the subjects reveated dissatisfaction. 4) Preference orders in relation to the expansion of facilities appeared as follows; tennis court(24.5%), swimming pool(14.4%), badminton court(12.5%), gymnasium(11.4%) and football field(7.0%). 5) 76.1% of the sujbjects thought that physical activity contribute to reduce demoralized life style, but 3.2% of the subjects not thought so. 6) About present participation in physical activity, 31.8% of the subjects answered being participated, but the large majority(68.2%) of the subjects answered not being participated. 7) Subjects' favorite physical activitier are tennis(18.6%), mounteering (12.9%), football(8.9%), golf(8.6%), badminton(8.3%), jogging(8.3%), gymnasics(7.3%) and swimming(7.0%) 8) The places of physical activities are private facilities(33.4%), work place(13.6%), private house(12.6%), school(10.9%) and physical education park(9.3%). 9) 73.9% of the subjects answered that they were participating in physical activity for health improvement. 10) 70.6% of the subjects felt the necessity of coach of Sport for All. 11) In case of not attendance to the physical activity, 70.6% of them answered that the main reason of not attendance was lack of leisure. 12) In case of not attendance, 33.7% of them spared time to TV watching, 28.8% of them to housework and 18.0% of them to sleeping. 13) 13.5% of subjects wanted to participate in swimming, 12.9% to tennis, 11.7% to table tennis, 10.8% to mountaineering, and 10.3% to badminton if circumstances permit.

영아자(Phyteuma japonicum Miq.)의 성분 조성

정미자,신정혜,이수정,홍성국,강호중,성낙주 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.4

산채식물인 영아자(Horned Rampion ; Phyteuma japonicum Miq.)의 영양학적인 가치를 평가코져 야생 및 평지재배 시료를 잎과 줄기로 구분하여 일반성분, 비타민 C, 유리당, 무기물, 핵산관련물질, 구성 아미노산 및 유리아미노산을 분석하였다. 야생과 재배 영아자의 회분은 1.2∼2.7%의 범위였고, 조지방과 조단백질은 재배시료가 조섬유는 야생시료에서 더 높은 함량으로 정량되었고, 전당은 두 시료간에 대차를 보이지 않았다. 비타민 C는 줄기보다는 잎에서 재배시료보다는 야생시료에서 더 높게 정량되었다. 유리당은 야생 및 재배시료 모두 glucose, frucose 및 sucrose가 잎보다 줄기에서 높게 정량되었다. 무기물은 총 9종이 분석되었는데 이중 칼슘의 함량이 가장 높아 재배시료의 경우 잎은 34374.0㎎/㎏, 즐기는 9584.1㎎/㎏였고, 그 다음으로 칼륨, 마그네슘의 순으로 많았으며, 야생시료도 비슷한 경향을 보였다. 핵산 관련물질은 CMP, UMP, IMP, AMP 및 hypoxanthine이 동정되었는데 잎과 줄기 모두 야생시료에서는 hypoxanthine이, 재배시료에서는 AMP가 월등히 높게 정량되었다. 구성아미노산은 총 17종으로 야생시료에서는 glutamic acid, 재배시료는 잎의 경우 aspartic acid, 줄기의 경우 glutamic acid의 함량이 가장 많았다. 유리아미노산은 총 29종이 동정되었고 야생시료의 잎에서는 glutamic acid, 줄기에서는 γ-aminoisobutyric acid, 재배시료의 줄기에서는 asparagine이 가장 높은 함량으로 정량되었다. This research is to establish the basic data of the nutritive value and improve our diet. In the part of th leaf and stem of the wild cultivated horned rampion(Phyteuma japonicum Mig), the components such as chemical composition, vitamin C, free sugar, mineral, nucleotide and its related compounds, composition and free amino acid were analyzed one after another. Content of the crude lipids and proteins was determined much higher in its wildness than in its cultivated horned rampion ; while, that of carbohydrates was higher in the former than in the latter. The content of vitamin C was retained higher in the leaf than in the stem horned rampion. And the content of calcium among the detected minerals was outstanding in all of the samples collected, and potassium and magnesium was the next ones in its order. The main components of free sugars in both the wild and cultivated horned rampion were glucose and fructose, and their content was higher in the stem than in the leaf. Nucleotide and its related compounds were identified with 5 kinds of nuciotides such as CMP, UMP, IMP, AMP and hypoxanthine(Hx), and the content of Hx and AMP was the highest in the wild and cultivated samples, respcetively. In the composition amino acid of the wild horned rampion, glutamic acid, aspartic acid and phenylalanine was outstandingly abundant; while, such amino acid as methionine and proline was small and besides cysteine couldn't be detected in the stem. Total amounts of composition amino acid in the leaf was 2118.0 and 1120.1㎎% in the wild and cultivated sample, respectively. In the free amino acid of horned rampion, the total amount ranged from 8.5 to 50.1㎎%, which were lower level than that of composition amino acid. But the number of free amino acid was 29 kinds, which was bigger in its number than of composition amino acid detected 17 kinds.

골인이 Morphine 중독 마우스의 금단 증상에 미치는 효과

정태호,김정철,채성철,강병조,이인자 최신의학사 1991 最新醫學 Vol.34 No.2

경기지역 초등학생의 영양 불균형에 따른 혈중 지질 수준에 관한 연구

승정자 숙명여자대학교 건강·생활과학연구소 2004 生活科學硏究誌 Vol.- No.20

The purpose of this study was to investigate the blood lipid levels of insufficiently nourished elementary school students in Gyeonggi area. Subjects were assigned to deficiency or normal group according to the percent of energy RDA intake. Their nutritional status and serum lipid were evaluated based on questionnaire. anthrometric measurements. 24-hr dietary recalls and blood analysis. The mean age of total subjects was 10.8 years and the average height. weight and obesity index of deficiency and normal group was no significant different. At the result of comparison the Korean RDA with mean daily intakes. all nutrients intakes of normal group were approached the Korean RDA's 75 percentile. But vitamin A. vitamin B_(2). niacin. folate. calcium and zinc intakes of deficiency group were lower than the Korean RDA's 75 percentile. The average food intake of deficiency and normal group was no significantly different. Pulse intakes of deficiency group was significantly lower than that of the normal group(p<0.05). but the nuts and seeds intakes of deficiency group was significantly lower than that of the normal group(p<0.05). The HDL-cholesterol level of deficiency group was significantly lower than that of normal group(p<0.001) and atherogenic index(AI) was significantly higher than that of normal group(p<0.01). To summarize the result. vitamin A. vitamin B_(2). niacin. folate. calcium and zinc intakes of deficiency group were lower than the Korean RDA's 75 percentile. Pulse(p<0.05) and nuts and seeds(p<0.05) intakes were significant difference of deficiency and normal group. And deficiency group had lower HDL-cholesterol and higher atherogenic index than those of the normal group. Also it was suggested that the blood lipids might be related to the adequate nutrients intakes approached the Korean RDA's of elementary school students.

임신부의 일상 식이 중 철, 마그네슘 영양상태와 철 보충제의 복용이 혈청 철, 마그네슘의 함량에 미치는 영향

승정자 동아시아식생활학회 2000 동아시아식생활학회지 Vol.10 No.6

The purpose of this study was to assess the nutritional status of iron and magnesium and the effect of iron supplementation during 8 weeks(from 20 to 28 weeks of gestation) on serum iron and magnesium status of 31 pregnant women in Kyungin area. The age, weight, and height of the subjects before pregnancy were investigated by questionnaires. At 20 and 28 weeks of gestation, data for food and nutrient intake were obtained by questionnaires and serum sample was obtained. According to the frequency of iron supplementation, subjects were divided into two groups(4</wk, 5≥/wk). The mean iron supplementation of 5≥/wk group(63.9㎎/day) was significantly higher than 4</wk group(10.3㎎/day). The mean age of subjects was 30.1 years old. The weight of subjects was significantly increased at 28 weeks compared than those carried at 20 weeks of gestation(p<0.001). The energy and vitamin B2 intakes were much less than the Korean RDA. Especially, calcium, iron and magnesium intakes showed half the levels compared with Korean RDA. At 28 weeks of gestation the serum total protein (p<0.001) albumin(p<0.01) and globulin (p<0.001) were significantly decreased. Total iron binding capacity(TIBC) was significantly increased (p<0.001), but serum ferritin(p<0.01) and magnesium (p<0.01) concentrations were significantly decreased. However, even 28 weeks of gestation 5≥/wk group showed higher serum iron and ferritin concentration and lower TIBC than 4</wk group. Serum magnesium concentration was significantly decreased by progressing the pregnancy and was showed the decreasing trend at 5 ≥/wk group. Therefore, iron supplementation should be conducted with concerning the mineral balance like magnesium.

폐경후 여성의 비만도에 따른 영양상태와 항산화능에 관한 연구

승정자,김은영 대한비만학회 2003 The Korean journal of obesity Vol.12 No.3

연구배경: 여성은 폐경을 맞이하면서 호르몬의 변화 등으로 인해 비만 발생률이 높아지며, 그로 인해 만성퇴행성 질환 발병 위험을 초래한다. 이에 폐경 후 비만 여성에서 혈중 항산화효소 활성 및 혈중 지질양상을 비교하고자 하였다. 방법: 폐경 후 여성 60명을 대상으로 2001 국민건강 영양조사의 체질량지수 85th percentile 이상인 대상자를 비만군(27명), 그 이하는 대조군(33명)으로 분류하였다. 신체계측과 식이섭취조사, 혈액 채취를 실시하였고, 항산화효소인 superoxide dismutase, glutathione peroxidase, total antioxidant 활성을 측정하였다. 결과: 연구 차상자의 평균 연령은 비만군이 65.4세, 대조군이 64.2세로 두 군간에 유의적인 차가 없었고, 비만군의 체중(p<0.001), 체질량지수(p<0.001), 허리-엉덩이 둘레비 (p<0.001), 체지방률(p<0.001)이 대조군에 비하여 유의적으로 높았다. 열량 섭취량은 1일 평균 비만군이 1551.4 kcal(권장량의89.4%), 정상군이 1516.1 kcal (권장량의 85.9%)로 두 군간에 유의적인 차이가 없었고, 영양소 섭취량도 두 군간에 유의적인 차이를 보이지 않았다 식품군별 섭취량 조사 결과 비만군의 감자 및 전분류(p<0.01), 난류(p<0.01)의 섭취량이 대조군보다 유의적으로 높았다 비만군의 심혈관계질환의 위험인자와 관련된 지표인 혈청 총 콜레스테롤(p<0.05), 중성지방(p<0.05)의 수준도 비만군이 대조군에 비하여 유의적으로 높았다 항산화효소 활성을 분석한 결과, SOD, GPx, TA 활성은 두 군간에 유의적인 차이가 없었다. 혈액지표간의 상관관차를 분석한 결과 혈중 총 콜레스테롤과 SOD가 양의 상관관계 (p<0.05)를 보였다. 결론: 비만군은 혈청 총 콜레스테롤과 중성지방의 수준이 대조군보다 높아 심혈관계질환의 위험도가증가한 것으로 나타났으며, 차상자의 혈청 총 콜레스테롤은 SOD 활성과 유의적인 양의 상관관계 (p<0.05)를 보임으로써 비만도 증가에 따른 혈중 지질 수준의 변화는 항산화능의 변화와도 관련이 있을 것으로 보여진다. Background: Increases in the number of obese population is an international issue, and Korea is not an exceptional case. In postmenopausal women changes in hormonal profiles may raise a problem of obesity. Obesity is correlated to chronic degenerative diseases and the antioxidant status. The purpose of this study was to compare the antioxidant enzyme activities and serum lipid of obese postmenopausal women to those of non-obese subjects, and investigate the relationship among nutritional status, BMI, and antioxidant enzyme activities in postmenopausal obese women. Methods: In this study, we classified the subjects in to the obese postmenopausal women(n=27) and non-obese (n=33) according to their BMI, and measured dietary intakes, serum lipid, SOD (Superoxide dismutase activity), GPx (Glutathione peroxidase activity) and TA (Total antioxidants capacity). Results: The average age of obese and non-obese were 65.4 yrs and 64.2 yrs, respectively and there was no significant difference. Body weight (p<0.001), body mass index (P<0.00l), waist-hip ratio (p<0.001) of obese were significantly higher than those of non-obese. The mean daily intake of energy in obese and non-obese subjects were 1551.4 kcal (89.4% of RDA) and 1516 kcal(85.9% of RDA), respectively and there was no significant difference. The mean daily nutrient intakes of obese was not significantly from those of non-obese subjects. The obese consumed significantly greater quantities of potatoes (P<0.0l) and eggs (P<0.01) compared those consumed by non-obese. Serum total cholesterol (p<0.05), triglyceride (P<0.05) of obese were significantly higher than those of non-obese. There was no significant difference in SOD, GPx, TA activities. A significantly positive relationship was present between total cholesterol and SOD (p<0.05). Conclusion: Obese postmenopausal women had higher serum total cholesterol and triglyceride than those of the non-obese. Obesity is associated with elevated antioxidant enzyme activities. And that perdisposes the cardivovascular disease to oxidative stress.

가열조리한 돼지고기의 저장·Microwave 재가열에 의한 변이원성과 지질과산화 및 육조직에 관한 연구

정경숙,구성자 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.6

Pork was cooked using three kinds of instrument [electric grill (EG) for 5min., microwave oven (MW) for 6min. and reheated using a MW] and then extracted with 80% methanol. The Ames test was performed on the methanol extracts, employing the S. typhimurium tester strain, TA100. The methanol extract of cooked pork showed high mutagenicity ion the 5.0 mg/plate without the S9 mix, but a higher mutagenicity was induced with the S9 mix With increasing refrigeration (4℃) and freezing (-18℃) periods the extracts showed higher mutagenicities and TBA values, and the same results where shown with reheating. Correlations of the mutagenicity (-S9 mix) and rancidity of the pork cooked by EG, according to storage at and -18 ℃ and reheated by MW (1 min), were r=0.85, 0.86, 0.98 and 0.83, respectively. When the MW was used for reheating, the refrigeration storage (r=0.98) showed a higher correlation coefficient than for that stored frozen (r=0.83). From the structure of cooked pork, as observed by SEM, many vapor pathways were viewed in the pork reheated using themicrowave oven.