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金正洙,李鍾夏,徐相壽 忠州大學校 1968 한국교통대학교 논문집 Vol.2 No.-
In this paper ; I examined the condition for proper illumination with the study of its influence on our daily life and our health, and of the ideal illumination of our houses, buildings and facfories, on the standpoint of human engineering and I made an attempt to study on these problems through the examination in the influence of proper illumination on our sight, with one thousand children of the fourth, the fifth, and the sixth grade of the primary school in the city of Chungju as an object of the study.
박정삼,손동수,이상훈,김진태,한세현,장기택,김종철 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2
It has widely known for speech problem in patients with malocclusion,but there have been insufficient studies on degrees of serverity.Patients with openbite and CIⅢ malocclusion usually have speech problem.It has widly known that fricative /s/ is pronunciated most abnomally in CIⅢ malocclusion than any other consonant.Therefore 20 childen with anterior crossbite selected for control group.7 sounds such as /사(sa),서(sδ),소(so),수(su),스(sω),시(si),세(se)/ were recorded,and the formants and formants ratio were measured by using Sensimetric Speech Station,which is speech analyzing program in IBM pc. The results were as follows: 1.In anterior crossbite group,F1 of all 7 sounds were significantly higher than normal anterior relationship group(P<0.05). 2.There were no significant difference in F2 between two groups except/소(so),수(su)/(P>0.05). 3.In anterior crossbite group,F2/F1 ratio of all 7 sounds were significantly smaller than normal anterior relationship group(P<0.05). 4.There were no significant difference in accordance with tongue position(P>0.05).
이수진,김영재,장기택,이상훈,김종철,한세현,김정욱 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.2
X-linked hypophosphatemic rickets(이하 XLH로 기술)는 구루병의 일종으로 임상적으로는 비타민 D의 대량 투여로도 개선되지 않고 성염색체 우성 유전되는 유전성 질환이다. 저인산혈증성 구루병, 비타민 D 저항성 구루병이라고도 불린다. 본 증례는 서울대학교병원 소아과에서 XLH로 진단받은 6세 6개월의 여아로, 상악 좌측 중절치의 매복을 주소로 소아치과에 의뢰된 환자이다. 환아는 XLH 환자에서 전형적으로 보이는 보행 장애, 다리의 휨현상, 작은 키, 손목, 무릎, 발목 관절의 종창 등이 관찰되었다. 또 치과적 특징으로 임상적으로 건전한 치아에서 자발적인 치근단 농양과 농루가 발생하였고 치아의 맹출지연, 우상치 (taurodontism), 근단공의 폐쇄 지연, 확대된 치수강 등을 나타내었기에 이전 문헌 고찰을 통하여 XLH 환아의 특징을 살펴보고 본 환자의 의과적, 치과적 특성 및 매복된 치아의 치료에 대하여 보고하는 바이다. XLH(X-linked hypophosphatemic rickets) is a form of rickets which is resistant to the usual dose of vitamin D and inherited in a X-linked dominant manner. It is also known as vitamin D-resistant rickets or familial hypophosphatemic rickets. Here we report a 6-year-and-6-month-old female patient of XLH who is diagnosed with in SNUH. She was referred from local clinic for impaction of maxillary left permanent incisor and its treatment. She presents bowing deformities of the legs, short stature, enlargement of wrist and ankles and spontaneous dental abscesses of clinically sound teeth, delayed eruption, taurodontism, delayed apical closure, enlarged pulp chambers, and absent or poorly defined lamina dura. The purpose of this case is to review the literatures of XLH and report the dental and medical characteristics of this patient.
ATYPICAL MESOBLASTIC NEPHROMA 1례
박만수,이중화,윤율로,설종구 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1
Atypical mesoblastic nephroma is a rare infantile renal tumor that may behave aggressively in older infants. The features that distinguish atypical mesoblastic nephroma from congenital mesoblastic nephrorma are as follows; (1) atypical gross features consisting of one or more of the follwing: flesh areas, foci of hemorrhage, necrosis, involvement of adjacent structures; and (2) high cellularity and mitotic index. Treatment is not established whether additional modes of therapy are indicated in completely resected atypical mesoblastic nephroma. A close and regular periodic follow-up is indicated in all cases of atypical mesoblastic nephroma. A case of atypical mesoblastic nephroma in 45-day-old-male is presented with brief review of literatures.
박종연,배수호 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.B
The most of metalhalide lamps is what the momentary restarting cannot be realized when the arc tube is in the hot condition. The discharge starting voltage of arc tube in the hot condition is much higher than in the cold condition in proportion to the gaseous pressure. Therefore it takes about ten minutes to restart the metal Halide lamps, that is to say, it is possible to start when the pressure and the temperature are decreased. But, if the lamp is restarted in the hot condition, we must supply the high voltage pulse with 15kV between the both electrodes of lamp. The proposed ignitor has two ignitors. If we connect each ignitor at the both sides, the high voltages of two different frequencies are generated. If so, when the one of the ignitor generates the highest voltage and the other applied to elecrodes of the lamp. In this way, we can restart the lamp with the voltage 15kV, even if the lamp is in the hot condition.
腎細胞癌에서 Flow Cytometry에 依한 核 DNA(Deoxyribonucleic Acid)量 測定
金瑩洙,薛鍾求 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2
From cytometry was used to analyze deparaffinized primary renal cell carcinoma specimens in 27 cases of 54 renal cell carcinoma patients to evaluate deoxribonucleic acid ploidy as a predictor of disease progression and survival in the Department of Urology, Chungnam University Hospital, from January 1985 to September 1992. DNA ploidy was analyzed according to cell type, cellular differentiation, clinical stage, tumor size. The results were as followings: 1. Renal cell carcinoma was most frequent in 6th decade, and male to female ratio was 1.5:1. 2. Cell type of renal cell carcinoma were clear type(44.5%), granular cell type(33.3%), mixed cell type(11.1%) and sarcomatoid(11.1%). 3. In 27 renal cell carcinoma analyzed by flow cytometry, 16 tumors were diploid stem line and 11 tumors were aneuploid stem line. 4. In DNA ploidy according to cell type, cellular differentiation, tumor stage and tumor size, aneuploid rates were 41.7% in clear cell type, 22.2% in granular cell type, 66.7% in mixed and sarcomatoid type respectively, and 31.2% in low stage tumor and 54.5% in high stage tumor, and 31.2% in high differentiated group and 54.5% in low differentiated group, and 20.0% in smaller than 5cm, 41.7% in 5-10cm and 50.0% in larger than 10cm in diameter(p>0.05). 5. In mortality according to cell type, cellular differentiation, tumor stage and DNA ploidy, 6 patients were died within 5 years in clear cell type(12 cases), 4 patients were died within 2 years in granular cell type(9 cases) and 2 patients were died within 1 year in sarcomatoid type(3 cases), and 6 patients were died within 5 years in highly differentied group(16 cases) and 6 patients were died within 2 years in low differentiated group(11 cases), and 5 patients were died within 5 years in low stage(16 cases) and 7 patients were died within 2 years in high stage(11 cases), and 6 patients were died within 5 years in diploid group(16 cases) and 6 patients were died within 2 years in aneuploid group(11 cases)(p>0.05).
조종수 서울대학교 농업개발연구소 1999 농업생명과학연구 Vol.3 No.-
A new mucoadhesive polymer was prepared by template polymerization of acrylic acid in the presence of poly(ethylene glycol)(PEG). FTIR results indicated that a polymer complex was formed between poly(acrylic acid)(PAA) and PEG through hydrogen bonding. The hydrogen bonding in the PAA/PEG polymer complex was stronger than that in the PAA/PEG blend, and became stronger as the molecular weight of PEG increased. Glass transition temperatures(Tg) of PAA in the PAA/PEG polymer complexes was shifted to a lower temperature than that of PAA in the PAA/PEG blend. However, they tended to become higher as the molecular weight of PEG increased. The dissolution rate of the PAA/PEG polymer complex was much slower than the PAA/PEG blend, and was dependent on pH and molecular weight of the PEG. The mucoadhesive force of the PAA/PEG polymer complexes was stronger than for the PAA/PEG blend or a commercial product, Carbopol 971PNF.
조종수,정영일,나재운,김성호 朝鮮大學校 1997 藥學硏究誌 Vol.18 No.2
양말단에 이크릴레이트를 갖는 폴리에틸렌글리콜 미크로마(PEG macromer)와 또한 PEG macromer와 폴리하이드록시에칠메타아크릴레이트[P(HEMA)] 혹은 폴리(하이드록시에칠메타아크릴레이트-하이드록시프로메타아크릴레이트-비닐피롤리돈)[P(HEMA-co-HPMA-co-NVP)]와 상호침투된 망상구조의 시료가 소프트콘텍트렌즈의 알부민의 흡착을 막기위하여 제조되었다. PEG macromer의 중합으로 macromer의 다관능성기로 인하여 가교된 겔이 형성되었다. P(HEMA-co-HPMA-co-NVP)/PEG IPN계 콘텍트렌즈에서 PEG분자량이 중가할수록 알부민의 흡착량은 감소되었다. 또한 IPN제조시의 PEG의 농도가 짙을수록 알부민의 흡착량은 감소되었다. PEG macromer와 IPN하기전의 P(HEMA)계 및 P(HEMA-co-HPMA-co-NVP)계의 콘텍트렌즈에 비하여 PEG macromer와 IPN함으로서 렌즈의 착용감이 훨씬 상승되었다. Poly(ethylene glycol)(PEG) macromers terminated with diacrylate groups and interpenetrating polymer networks(IPN) composed of poly(hydrowyethyl methacrylate)(PHEMA) or poly(hydrowyethyl methacrylate-co-hydroxypropyl methacrylate-co-N-vinyl pyrrolidone)[P(HEMA-co-HPMA-co-NVP)]and PEG macromer were synthesized with the aim of abtaining protein adsorption resistant soft contact lens. Polymerization of PEG macromer. Crosslinked p(HEMA)or P(HEMA-co-HPMA-co-NVP) chains were interpenetrated into the cross-linked three-dimensional networks of PEG. It was found that albumin adsorption onto the contact lens prepared by P(HEMA-co-HPMA-co-NVP)/PEG IPN decreases with an increase of molecular weight of PEG. Also, it was found that albumin adsorption onto the both contact lens decreases with an increase of concentration of PEG macromer in the IPN preparation. There are also more adequate in the biointerness for the contact lens by P(HEMA)/PEG IPN or P(HEMA-co-HPMA-co-NVP)/PEG IPN than that by P(HEMA) or P(HEMA-co-HPMA-co-NVP).
Propylthiouracil에 의한 중증 급성간염 1예
임종주,심미령,이명수,김태현,오석규,안선호,박무림,김남호,박병현,조성구 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.2
PTU에 의한 간염의 발생은 매우 드물게 발생하는 것으로 알려져 있으나 저자들은 Graves씨 병으로 진단 받고 propylthiouracil 투여를 받고있던 환자에서 중증의 급성 간염이 발생한 1예를 경험하였기에 보고하는 바이다. Propylthiouracil is widely used to treat patients with hyperthyroidism. This drug has been associated with severe hepatotoxicity rarely. We presented the case of jaundice and profound liver dysfunction from a 23-year old woman treated with propylthiouracil for hyperthyroidism. Viral, metabolic, and autoimmune liver disease could be excluded and liver biopsy revealed a pattern of acute hepatitis. After discontinuing the drug, there was a progressive resolution of hepatic symptoms and decrease in biochemical data of the liver. Despite propylthiouracil induced hepatitis in rare case, patients receiving propylthiouracil are exposed to develope severe hepatotoxicity. Therefore it might be advisable to monitor level of the transaminase on regular base from patients receiving propylthiouracil.