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西獨 技術科 敎育課程에 관한 硏究 : 니더작센주와 노르트라인 베스트팔레주를 중심으로
金振淳,韓用萬 충남대학교 공업교육연구소 1988 論文集 Vol.11 No.1
This study investigated the character, objectives, tea¨ching contents and methods of 'Arbeitslehre' at the Lower Saxony and North Rhine Westphalia State in the Federal Republic of Germany. 1. In general the 'Arbeitslehre' is taught in the secondary school as an integrated subject combined work, economy, technology and home economics, because these subjects have some common elements for students to adapt to the future world of work and economy. 2. The objectives of the 'Arbeislehre' is to provide experience and knowledge about fact, structures and conditions of the world of work and economy for the pupils, which help them to find their individual way into their daily and vocational life. 3. Main teaching contents of the 'Arbeitslehre' are 1) the organization and role of enterprise 2) economy and consumption 3) vocational guidance 4) working conditions in the 'work/economy' subject, 1) electricity and electronics 2) machining and manufacturing 3) construction in the 'technology' subject, and 1) organization of household affairs 2) management of domestic econonmy 3) family education in the 'home economics'subject. 4. The distintive fecture of teaching methods is to secure congruence between theory and practice by means of fieldtrip, on-the-job practice, project method, case study, etc.
제4형 가족성 고중성지방혈증 임산부에서 발생한 급성 췌장염 1례
박관응,윤채중,김영학,진영기,윤성호,권용은,김태원,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2
Plasma levels of cholesterol (TC) and triglyceride(TG) physiologically increase during pregnancy. The lipid increment is 23-53% above the pregravidic level for TC and 2- to 3-fold of the prepregnancy level for TG. If the TC and TG are higher than normal values in pregnancy, the patient must be carefully monitored. Acute pancreatitis is the main consequence of hyperlipidemia and occurs either during pregnancy, in the third trimester, or in the puerperium. Mortality is high both for the mother (21%) and the fetus (20%). We report a case of 28 year-old pregnant woman at 29 weeks gestation with hypercholesterolemia (TC = 357 ㎎/dl) and severe hypertriglyceridemia (TG = 1300 ㎎/dl). The patient was admitted to the hospital because of severe epigastric pain, nausea and vomiting. Total serum cholesterol was increased and trigyleride was markedly increased. The electroporesis pattern of serum lipoprotein showed increase in pre-beta lipoprotein fraction, suggesting IV hypertriglyceridemia pattern. According to a review of the literature, the incidence of pancreatitis during pregnancy is 1 in 1000 to 3000 pregnancies. Severe hypertriglyceridemia in pregnancy should be treated with a careful restriction of calories and fat: for preventing acute pancreatitis, hospitalization for intravenous fluid therapy and plasma exchange must be required.
트리아릴포스포늄 염과 카르보닐 화합물 사이의 위티그 반응의 입체선택성에 대한 고압 효과
김정성,최정훈,지진영,김창만,김용훈 대구대학교 기초과학연구소 1999 基礎科學硏究 Vol.15 No.3
The Wittig reactions of triarylphosphonium ylides with various carbonyl compounds under high pressure were carried out to investigate its effect on the cis-trans stereochemical outcome. Generally, the cis-stereoselectivities at atmospheric pressure are known to be resulted from smaller steric hindrance of α-carbon of carbonyl group with hydrogens of phenyl residue of triphenylphosphonium ylide and in oxaphosphetane intermediate stage. Thus, the steric interactions between triphenylphosphonium ylide and carbonyl compounds in the transition state can be maximized. And, the reactions of semistabilized ylide and stabilized ylide at atmospheric pressure generate mainly thermodynamically more stable trans-alkane after formation of betaine intermediate. The reactions at high pressure, however, can generate cis-alkene more exclusively through oxaphosphentane intermediate,directly without the formation of betaine intermediate by reducing distance between ylide and carbonyl compound. Reaction between benzyl triphenylphosphonium ylide, a semistabilized ylide, and butyraldehyde at atmospheric pressure gave cis-1-phenyl-1-pentene with 34/66 of Z/E stereoselectivity, but when pressurized at 10000 bar, cis-alkene with 69/31 the Z/E ratio was excellently yielded than trans-alkene. In the case of Wittig reaction of ethoxyacetyl triphenylphosphonium ylide, a stabilized ylide, with butyraldehyde, Z/E stereoselectivity at 10000 bar was inversed in contrast to atmospheric pressure.
열복사의 색수차 공간여과를 이용한 레이저 용접 감시기술
김민석,백성훈,박승규,정진만,김철중 한국레이저가공학회 1999 한국레이저가공학회지 Vol.2 No.2
An innovative real-time weld monitoring technique using chromatic filtering of the thermal radiation from a weld pool is developed. This thermal radiation from the weld pool is focused on an aperture and the transmitted thermal radiation is monitored at two wavelengths with high-speed single-element detectors. Due to the chromatic aberration introduced in the focusing optics, the transmittance curve of thermal radiation varies by the wavelength. Owing to this difference in the transmittance, the local variation of thermal radiation from the weld pool can be monitored by processing the two spectroscopic signals from two detectors. In this paper, the algorithms to monitor the laser power on the weld specimen and the focus shift are investigated and the performances of laser power and focus monitoring are shown for a pulsed Nd:YAG laser welding. The monitoring of the weld pool size variation is also discussed.
( Man Chin Hua ),( Hsun Chin Chao ),( Tsung Chieh Yao ),( Ming Wei Lai ),( Jing Long Huang ),( The Patch Study Group ) 대한소화기학회 2013 Gut and Liver Vol.7 No.4
Background/Aims: The aim of this study was to investigate whether genetic variations at positions -1082, -819, and 592 in the interleukin (IL)-10 promoter affect IL-10 production in children with irritable bowel syndrome (IBS). Methods: Ninety-four children with IBS and 102 children as healthy controls (HCs) were enrolled. Genomic DNA was extracted, and IL-10 -1082, -819, and -592 polymorphisms were detected by direct sequencing from all participants. Peripheral blood mononuclear cells (PBMCs) from 46 IBS children and 38 HCs were isolated and cultured with and without 5 ng/mL Escherichia coli lipopolysaccharide (LPS). IL-10 levels in the culture supernatants were measured by enzyme-linked immunosorbent assay. Results: There were no significant differences in the distribution of IL-10 -1082, -819, and -592 polymorphisms or in the allele and haplotype frequencies between IBS children and HCs. PBMCs from children with IBS had significantly lower IL-10 levels after LPS stimulation than PBMCs from HCs (p=0.011); however, LPS-induced IL-10 levels in PBMCs with different genotypes of -819 and 592 polymorphisms were not significantly different between IBS patients and HCs. Conclusions: Although significantly lower LPS-induced IL-10 production by PBMCs was noted, it is unlikely that IL-10 production was fully genetically determined in our IBS children. ClinicalTrials.gov identifier: NCT01131442. (Gut Liver 2013; 7:430-436)
금속표면 특성향상을 위한 Iaser peening 효과
정진만(Chin-Man Chung),백성훈(Sung-Hoon Baik),김정수(Joung-Soo Kim),이상배(Sang-Bae Lee) 한국레이저가공학회 2008 한국레이저가공학회지 Vol.11 No.3
The effect of a laser peening on the surface residual stress of SUS 304 was investigated using a second harmonic Nd:YAG laser beam. The energy density and the diameter of the laser beam were 400 mJ/㎟ and about 1㎜, respectively. According to the test results, the effect of a laser peening for improving the surface residual stress was not big enough to induce a high compressive stress on the SUS 304 surface. This is thought to be attributed to the small radius of the laser beam used in this study, even though its energy density is big enough. From this study, it can be concluded that to induce a recognizably high compressive stress on a metal surface, the energy density as well as the size (diameter) of the laser beam should be large enough to generate surface plasma with a high energy to have a big impact to a metal surface.
α-galactosidase A 유전자 분석으로 확인된 Fabry 병
진범식 ( Bum Sik Chin ),김지인 ( Jee In Kim ),이진성 ( Jin Sung Lee ),홍순원 ( Soon Won Hong ),정현주 ( Hyun Joo Chung ),김희만 ( Hee Man Kim ),김동기 ( Dong Ki Kim ),구영석 ( Young Suck Goo ),이호영 ( Ho Yung Lee ) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.6
Fabry disease is a X-linked lysosomal storage disorder caused by deficiency of α-galactosidase A. This abnormality in enzyme results intracellular accumulation of globotriaosylceramide and leads to severe painful neuropathy with progressive renal cardiovascular, and cerebrovascular dysfunction and early death. We report a 35 year-old man who had been suffered from acroparesthesia aggravated by body temperature elevation and with asymptomatic renal function impairment, which were proven to be due to Fabry disease. We performed gene analysis by PCR direct sequencing and confirmed missense mutation of GLA gene. Recently enzyme replacement of α-galactosidase was introduced and we think that the importance of early diagnosis and treatment should be emphasized.