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MPEG-2 비디오 디코더(MP@HL)의 상위 레벨 설계에 관한 연구
박준호,오주환,천성권 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(A)
In this paper, high level of MPEG-2 video MP@HL decoder is designed and follows ISO/IEC 13818-2 standard specification. MPEG-2 video decoder consists of system processign board, slice processign board, and motion processing board, which is compatible with MPEG-TS and MPEG layer-2. Each board represents schematic level design and external interface.
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박세진,김희규,김봉준,이천우,옥철호,정만홍 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2
우리나라에서 인기 있는 게장등의 섭취로2) 성인뿐만 아니라 소아에서도 지속적으로 보고되고 있는 폐흡충증은 다양한 임상양상을 보일 수 있다. 저자들은 방사선 소견상 만성 호산구성 폐렴과 유사하였고, 반복적인 치료로 호전된 폐흡충증 1예를 경험하였기에 보고하는 바이다. Paragonimiasis mostly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. Recently, re-emergence of paragonimiasis is reported because of ingestion of raw food such as freshwater fish and Gejang (marinated raw crabs). As the radiological features as well as the laboratory findings are similar to those of chronic eosinophilic pneumonia, the diagnosis of pulmonary paragonimiasis is often difficult and delayed. A 43 year-old female was visited our hospital for migrating and new developing consolidative lung lesions and peripheral blood eosinophilia. The eosinophil profile of leukocyte was 32% (absolute count 2,690 /mm3). Histologic finding was organizing pneumonia pattern with severe infiltration of eosinophils. Parasite specific antibody IgG forParagonimus westermani was positive (titer:0.61, normal range<0.20). After treatment with praziquantel (75mg/Kg once a day for 2days), the chest x-ray was clearly resolved. Follow-up study showed right pleural effusion, newly developed focal infiltration, and several nodules. After retreatment, we couldn't find any recurrent evidence.
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2 CASES OF RABBIT SYNDROME : 토끼증후군 2례
민병근,이창화,안준호,천두욱,김헌수 울산대학교 의과대학 1994 울산의대학술지 Vol.3 No.2
The application of neuroleptics to schizophrenic and other psychotic patients in the early 1950's led to the therapeutic revolution into the psychiatry, on the other hand neuroleptic-related adverse effects did frequently occur. The authors experienced 2 cases of rabbit syndrome producing by rare complication of neuroleptic medication. Two cases were examined for the rabbit syndrome by the description of Villeneuve(1972) and Sovner and DiMascio(1977). The reciprocal coordination test and the finger-tapping technique to worsen the symptoms also were applied to two patients. The authors emphasized two issues of rabbit syndrome as follows. First, though the literature search showed that the majority of patients presented with rabbit syndrome which is usually seen after a prolonged exposure to neuroleptic medication with the more potency in the middle or elderly aged are over 45 years old, we suggest that this syndrome might be linked to the younger age factor and the low potency thioridazine in our patient. Second, the rabbit syndrome is in the importance of the clinical practice because of being readily reversible with antiparkinsonian agents or anticholinergic drugs. In addition, recognizing this condition and differentiating it from tardive dyskinesia helps in the choice of the proper treatment of orofacial disorders following neuroleptic medication for the long time.
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Cheon, Seung-Hoon,Park, Joon-Suck,Jeong, Seon-Hee,Chung, Byung-Ho,Choi, Bo-Gil,Cho, Won-Jae,Kang, Boo-Hyon,Lee, Chong-Ock The Pharmaceutical Society of Korea 1997 Archives of Pharmacal Research Vol.20 No.2
5-Aryl-2,3-dihydroimidazo[2,1-a]isoquinolines were reported to have strong antitumor activity and one of the derivatives such as $5-[4^{l}$ -(piperidinomethyl)phenyl]-2,3-dihydroimidazo[2,1-a] isoquinoline (1, SDZ 62-434) was found to be more effective than the clinical cytostatic agent edelfosine (2) in in vitro and in vivo assays. Currently SDZ 62-434 is in clinical trials in Europe. The structure-activity relationship studies of SDZ 62-434 showed that compounds with substitution on ring A were less active than the lead compound. Ring B in SDZ 62-434 was essential for the activity because compounds without B ring had no antitumor activity. Among the 3-arylisoquinolin-1-one derivatives, $3-[4^{I}$-(piperidinomethyl)phenyl] substituted analog had no antitumor activity but simple phenyl substituted compound, such as 4, showed the most potent antitumor activity in various human tumor cell lines.
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Studies on the Synthesis and In Vitro Antitumor Activity of the Isoquinolone Derviatives
Cheon, Seung-Hoon,Lee, Joon-Yeol,Chung, Byung-Ho,Choi, Bo-Gil,Cho, Won-Jea,Kim, Tae-Sung The Pharmaceutical Society of Korea 1999 Archives of Pharmacal Research Vol.22 No.2
3-Arylisoquinolin-1(2H)-ones (2) are possible bioisosteres of the $5-[4^{l}-(piperidinomethyl)phenyl]-2<$,3-dihydroimidazo[2,1-$\alpha$]isoquinoline (1) which is in clinical evaluation for the treatment of cancer. Structure-activity relationship studies of 3-arylisoquinolin-1(2H)-ones. (2) led to the synthesis of 3-arylquinolin-2(1H)-ones (3). A number of 3-phenyl substituted quinolin-2(1H)-ones were synthesized and tested for their in vitro antitumor activity against four different human tumor cell lines and 3-phenyl-N-benzyl-3,4-dihydroquinolin-2(1H)-one (12) showed the most potent activity.
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Cheon, Seung-Hoon,Park, Joon-Suck,Chung, Byung-Ho,Choi, Bo-Gil,Cho, Won-Jae,Choi, Sang-Un,Lee, Chong-Ock The Pharmaceutical Society of Korea 1998 Archives of Pharmacal Research Vol.21 No.2
A number of substituted isoquinolin-1-ones, possible bioisosteres of the 5-aryl substituted 2,3-dihydroimidazo[2,$1-a$]isoquinolines, were synthesized and tested for their antitumor activity against five different human tumor cell lines. O-(3-hydroxyporpyl) substituted compound (15) exhibited the best antitumor activity which is 3-5 times better than 5-[$4^1$-(piperidinomethyl)phenyl]-2,3-dihydroimidazo[2,$1-a$]isoquinoline (1).
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Cheon, Seung Hoon,Park, Joon Suck,Jeong, Seon Hee,Chung, Byung Ho,Choi, Bo Gil,Cho, Won Jea,Kang, Boo Hyon,Lee, Chong Ock 전남대학교 약품개발연구소 1997 약품개발연구지 Vol.6 No.1
5-Aryl-2,3-dihydroimidazo[2,1-a]isoquinolines were reported to have strong antitumor activity and one of the derivatives such as 5-[4'-(piperidinomethyl)phenyl]-2,3-dihydroimidazo[2,1-a] isoquinoline (1, SDZ 62-434) was found to be more effective than the clinical cytostatic agent edelfosine (2) in in vitro and in vivo assays. Currently SDZ 62-434 is in clinical trials in Europe. The structure-activity relationship studies of SDZ 62-434 showed that compounds with substitution on ring A were less active than the lead compound. Ring Bin SDZ 62-434 was essential for the activity because compounds without B ring had no antitumor activity. Among the 3-arylisoquinolin-1-one derivatives, 3-[4'-(piperidinomethyl)phenyl] substituted analog had no antitumor activity but simple phenyl substituted compound, such as 4, showed the most potent antitumor activity in various human tumor cell lines.
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Structure-Activity Relationship Studies of Isoquinolinone Type Anticancer Agent
Cheon, Seung Hoon,Park, Joon Suck,Lee, Joon Yeol,Lee, You Na,Yi, Hyo,Chung, Byung-Ho,Choi, Bo-Gil,Cho, Won-Jea,Choi, Sang-Un,Lee, Chong-Ock 전남대학교 약품개발연구소 2001 약품개발연구지 Vol.10 No.-
Substituted isoquinolin-1 -ones (1) were synthesized to test their in vitro anticancer activity. 3-Biphenyl-N-methylisoquinolin-1-one (7) showed the most potent anticancer activity against five different human cancer cell lines.
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