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The 8th Biennial Meeting of the Asian Society of Gynecologic Oncology, December 1st to 3rd, 2023
Heng-Cheng Hsu,김재원,박정열,서동훈,김세익,Jen-Ruei Chen,Peng-Hui Wang 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.2
As per the 2018 GLOBOCAN database, Asia accounted for 48.7% (637,761) of new gynecologiccancer cases and 50.1% (305,000) of gynecologic cancer deaths [1]. Recognizing the distinctdifferences in genetic background, cancer epidemiology, disease characteristics, and socio-cultural environment between Asian and non-Asian women, it is noteworthy that much ofthe experimental evidence guiding clinical gynecologic oncology practices has historicallybeen drawn from studies in Western populations. Established in 2008, the Asian Society ofGynecologic Oncology (ASGO) ser ves as a key organization in Asia, dedicated to advancingthe study, prevention, and treatment of gynecological cancer through scientific exchange,regional/international collaboration, educational initiatives, and fostering camaraderieamong its members [2]. Presently, ASGO boasts members from over 10 countries in Asia. Building on the success of the previous meetings held in Tokyo (2009) [3], Seoul (2011)[4], Kyoto (2013) [5], Seoul (2015) [6], Tokyo (2017) [7], Incheon (2019) [8], and Bangkok(2021) [9], the eighth Biennial Meeting of ASGO took place at the state-of-the-art HNBKInternational Convention Center in Taipei, Taiwan, from December 01 to 03, 2023. Theoverarching theme for this event was “Reunion to Overcome Gynecologic Cancer in Asia.”Notably, due to the impact of the coronavirus disease 2019 pandemic in 2021, the meetingwas transformed into a hybrid format. This gathering marked a significant milestone as thefirst in-person Pan-Asia meeting focused on gynecological cancer following the pandemic. Additionally, it is worth highlighting that this was the inaugural ASGO meeting held outsideof Korea and Japan, underscoring the broadening geographical scope and global impactof the conference. Professor Peng-Hui Wang and Jae-Weon Jim chaired the organizingcommittee. ASGO 2023 witnessed the participation of 633 attendees from 17 countries,featuring 152 honored speakers and chairs from 12 countries. The event included 44 oral/surgical video presentations and 187 poster presentations, covering a diverse range ofscientific topics, from fundamental principles of gynecological cancer care to advanced, high-technology practices rooted in cutting-edge research (Table 1). Photos from the meetingare accessible on the official meeting website (http://tinyurl.com/26xtts2f ).
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Cheng-yong Cao,Cheng-hua Shi,Ming-feng Lei,Li-min Peng,Ruxue Bai 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.8
Hongmian Road goes under Jihe highway by the way of tunnel in Shenzhen City, Guangdong Province, China. The tunnel hassome special characteristics such as shallow depth, large span, soft soil, busy traffic, and long distance under-crossing the operatinghighway, thus there is great difficulty and risk during its construction. A series of in-situ tests were conducted to reveal deformationcharacteristics during tunneling beneath the existing highway by the double-side-drift method (DSDM). The results show that initialconstruction method and measures can't meet the safety requirement of tunnel construction, and the level of risk is extremely high, sothe construction method need to be timely adjusted. By comprehensive analysis, the double-side-drift optimum method (DSDOM) isput forward, on the basis of which a series of optimum measures also have been put forward, such as reasonable constructionmethods, the suitable length of bench and excavation, soil reinforcement measures on tunnel face, optimizing construction process,closing primary support in time and speeding up the construction of secondary lining. Then the feasibility of this optimizedconstruction method and measures are verified by the numerical simulations. Finally, from feedbacks of monitoring results, theoptimum method and measures have been proved to be reasonable and feasible, and they can guarantee a successful pass beneath theoperating highway.
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Cheng Peng,Yang He,Cao Deng,Liang Xiong,Shishang Qin 한국유전학회 2016 Genes & Genomics Vol.38 No.11
Pogostemon cablin (Blanco) Benth. is an important medicinal plant; however, its molecular biology remains largely unexplored. Here, we report the results of whole transcriptome-wide analyses of P. cablin using nextgeneration sequencing technology. In the present study, we generated 108,996 unigenes using RNA sequencing data. Among these unigenes, 65,536 were annotated in the NR database. There were 40,670 intact open reading frames (ORFs), which accounted for 69 % of the 58,820 predicted ORFs, demonstrating that our assembled transcriptome was of high quality. Gene expression levels in the leaf and stem were quantified, and 18,481 unigenes (17 %) were determined to be significantly differentially expressed. The patchouli alcohol (PA) and pogostone (PO) metabolic pathway of P. cablin was also reconstructed, and among the 17 putative homologs to PA and PO biosynthesis-related genes, seven were significantly upregulated in the stems, and three genes were significantly upregulated in the leaves. The correlation between the essential oil contents of P. cablin and the potentially pivotal genes for PA and PO production were identified. Considering that the contents of PA and PO in leaves and stems are markedly different in the same plant and we did not detect any pattern in the expression levels of candidate genes between leaves and stems, we speculate that after the biosynthesis, more PA probably accumulates in the leaves, and more PO in the stems of P. cablin. The transcriptome of P. cabin will facilitate further researches on the molecular system biology of the Pogostemon genus, as well as the in-depth studyies of PA and PO biosynthesis and its potential applications for genetic engineering.
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Cheng Jiaxing,Sheng Dongfa,Shi Peng-peng 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.5
As an important supplement and development to crystallography, the applications about quasicrystal materials have played a core role in many fields, such as manufacturing and the space industry. Due to the sensitivity of quasicrystals to defects, the research on the fracture problem of quasicrystals has attracted a great deal of attention. We present a boundary collocation method to research fracture problems for a finite dimension rectangular one-dimensional hexagonal quasicrystal plate. Because mode I and mode II problems for onedimensional hexagonal quasicrystals are like that for the classical elastic materials, only the anti-plane problem is discussed in this paper. The correctness of the present numerical method is verified through a comparison of the present results and the existing results. And then, the size effects on stress field, stress intensity factor and energy release rate are discussed in detail. The obtained results can provide valuable references for the fracture behavior of quasicrystals.
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Study of Neurotoxic Effects and Underlying Mechanisms of Aconitine on Cerebral Cortex Neuron Cells
Cheng Peng,Tao Zheng,Fan Yang,Yun-Xia Li,Ding-Kun Zhang 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.11
The study investigated the neurotoxic effects and underlying mechanisms of aconitine on cerebral cortex neuron cells prepared from neonatal SD rats. The uniform design and MTT method were applied to study the effect of aconitine with different concentrations at scheduled time. The influence of aconitine at the maximal toxicity concentration was observed using optical microscope and electron microscope. The influences of aconitine on neuron cells membrane, neuron cells’ inner balance, energy metabolism and neurotransmitters were observed to investigate the action mechanisms of aconitine. The results indicated that the maximal toxicity-concentration was 2% and the critical time were 30 s, 1 min and 20 min respectively. The effects of aconitine on neuron cells’ morphology included cells synapse’s fracture, cells membrane fragment, mitochondria’s swell, cytoplasmic vacuoles, nuclear chromatin’s condensation and accumulation. The stability of biomembrane, the internal milieu and the energy metabolism were also disturbed with the increase of activity of LDH and concentration of neurotransmitters (acetylcholine, opioid, catecholamine and SP) in culture medium, the increase of the activity of ACP and [Na+], [Ca2+] concentration, and the decrease of Na+-K+-ATP, [K+], [Mg2+] and glycogen concentration in the cells. Toxic mechanisms of aconitine damaging neuron cells may be because it inhibited the activity of Na+-K+-ATP, influenced the concentrations of [Na+], [K+], [Ca2+], [Mg2+] and neurotransmitters in the cells, which resulted in the injuries of cells’ morphology and function.
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Peng, Cheng,Mansour, Alaa M.,Wu, Chunfa,Zuccolo, Ricardo,Ji, Chunqun,Greiner, Bill,Sung, Hong Gun Techno-Press 2018 Ocean systems engineering Vol.8 No.4
Floating Production Storage and Offloading (FPSO) units have the advantages of their ability to provide storage and offloading capabilities which are not available in other types of floating production systems. In addition, FPSOs also provide a large deck area and substantial topsides payload capacity. They are in use in a variety of water depths and environments around the world. It is a good solution for offshore oil and gas development in fields where there is lack of an export pipeline system to shore. However due to their inherently high motions in waves, they are limited in the types of risers they can host. The Low Motion FPSO (LM-FPSO) is a novel design that is developed to maintain the advantages of the conventional FPSOs while offering significantly lower motion responses. The LM-FPSO design generally consists of a box-shape hull with large storage capacity, a free-hanging solid ballast tank (SBT) located certain distance below the hull keel, a few groups of tendons arranged to connect the SBT to the hull, a mooring system for station keeping, and a riser system. The addition of SBT to the floater results in a significant increase in heave, roll and pitch natural periods, mainly through the mass and added mass of the SBT, which significantly reduces motions in the wave frequency range. Model tests were performed at the Korea Research Institute of Ships & Ocean Engineering (KRISO) in the fall of 2016. An analytical model of the basin model (MOM) was created in Orcaflex and calibrated against the basin-model. Good agreement is achieved between global performance results from MOM's predictions and basin model measurements. The model test measurements have further verified the superior motion response of LM-FPSO. In this paper, numerical results are presented to demonstrate the comparison and correlation of the MOM results with model test measurements. The verification of the superior motion response through model test measurements is also presented in this paper.
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