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      • KCI등재

        Astrophysically Important 26Si States Studied with the 28Si(4He,6He)26Si Reaction

        Y. K. Kwon,이춘식,J. Y. Moon,J. H. Lee,J. Y. Kim,M. K. Cheoun,S. Kubono,H. Yamaguchi,J. J. He,A. Saito,Y. Wakabayashi,H. Fujikawa,G. Amadio,N. Iwasa,K. Inafuku,L. H. Khiem,M. Tanaka,Y. Fuchi,A. A. Chen,S 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.2

        The emission of a 1.809-MeV γ-ray from the first excited state of 26Mg, followed by β-decay of 26Al in its ground state (denoted as 26Alg.s.), has been identied by several gamma-ray telescopes. To resolve the controversy over the possible sources of the observational 1.809-MeV γ-rays, one needs accurate knowledge of the production rate of 26Alg.s.. The 25Al(p,γ)26Si reaction is one of the most important astrophysical reactions to be investigated, but its rate is uncertain due to the lack of level information on 26Si above the proton threshold (Qpγ = 5.518 MeV). Illiadis et al. suggested that the 25Al(p,γ)26Si reaction should be dominated by a 3+ unnatural parity state at Ex = 5970 keV. Recent studies proposed several states as candidates for the 3+ states. However, the spin-parity assignments for these states are still uncertain. In the present work, we measured the 28Si(4He,6He)26Si reaction at 120 MeV to confirm the unnatural parity states just above the proton threshold. The measurement was performed with the high-resolution particle analyzer at the Center for Nuclear Study, University of Tokyo. We observed a total of 22 excited states in 26Si. The 7018-keV level, which was only observed by Bardayan et al. with the 28Si(p; t)26Si reaction, was confirmed in our measurement. Among the candidates of unnatural parity states at Ex = 5678, 5916, and 5945 keV, the 5918-keV state was only observed within the error of the excitation energy. A new state at Ex = 6101 keV was also identified.

      • KCI등재

        Transparent conducting oxide glass grown with TiO2-nanotube array for dye-sensitized solar cell

        Chen-Hon Chen,Keh-Chang Chen,Ju-Liang He 한국물리학회 2010 Current Applied Physics Vol.10 No.2

        An arc ion plating (AIP) deposition system was employed to produce metal titanium layer on transparent conducting oxide glass, and followed by anodically oxidizing to form a TiO2-nanotube array electrode. A dye-sensitized solar cell (DSC) was then assembled as ITO glass/[TiO2-nanotube (N3 dye)]/I2 + LiI electrolyte/Pt/ITO glass. Anodizing bath composition was varied, and post-annealing was carried out. Consequent changes in the TiO2-nanotube array microstructure and photovoltaic efficiency of the assembled DSC device were revealed. Experimental results show that a 5-lm thick metal titanium layer can be obtained after 45 min AIP deposition. The metal titanium layer underwent complete conversion into XRD-amorphous TiO2-nanotube array after anodic oxidation for 2 h. The tube can reach 10.7 ㎛ long with tube inner diameter 92 nm. The ammonium fluoride in the anodizing bath accelerates the tube growth rate. Thermal annealing at temperatures over 250 ℃ works best on anatase crystallization of the TiO2-nanotube. An ultimate photovoltaic efficiency 1.88% (active area 1 ㎠) of the assembled DSC device can be obtained for the TiO2-nanotube grown ITO glass annealed at 350 ℃.

      • Analysis of Different Activation Statuses of Human Mammary Epithelial Cells from Young and Old Groups

        Feng, Chen-Chen,Chen, Li-Na,Chen, Mei-Jun,Li, Wan,Jia, Xu,Zhou, Yan-Yan,He, Wei-Ming Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

        Human mammary epithelial cells have different proliferative statuses and demonstrate a close relationship with age and cell proliferation. Research on this topic could help understand the occurrence, progression and prognosis of breast cancer. In this article, using significance analysis of a microarray algorithm, we analyzed gene expression profiles of human mammary epithelial cells of different proliferative statuses and different age groups. The results showed there were significant differences in gene expression in the same proliferation status between elderly and young groups. Three common differentially expressed genes were found to dynamically change with the proliferation status and to be closely related to tumorigenesis. We also found elderly group had less status-related differential genes from actively proliferating status to intermediate status and more statusrelated differential genes from intermediate status than the young group. Finally, functional enrichment analyses allowed evaluation of the detailed roles of these differentially-expressed genes in tumor progression.

      • Roles of Immunohistochemical Staining in Diagnosing Pulmonary Squamous Cell Carcinoma

        Yan, Yue,Zhang, Ya-Xiong,Fang, Wen-Feng,Kang, Shi-Yang,Zhan, Jian-Hua,Chen, Nan,Hong, Shao-Dong,Liang, Wen-Hua,Tang, Yan-Na,He, Da-Cheng,Wu, Xuan,Zhang, Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

        Background: Differentiating morphologic features based on hematoxylin-eosin (HE) staining is the most common method to classify pathological subtypes of non-small-cell lung cancer (NSCLC). However, its accuracy and inter-observer reproducibility in pathological diagnosis of poorly differentiated NSCLC remained to be improved. Materials and Methods: We attempted to explore the role of immunohistochemistry (IHC) staining in diagnosing pulmonary squamous cell carcinoma (SQCC) with poorly differentiated features by HE staining or with elevated serum adenocarcinoma-specific tumor markers (AD-TMs). We also compared the difference of epidermal growth factor receptor (EGFR) mutation rate between patients with confirmed SQCC and those with revised pathological subtype. Logistic regression analyses were used to test the association between different factors and diagnostic accuracy. Results: A total of 132 patients who met the eligible criteria and had adequate specimens for IHC confirmation were included. Pathological revised cases in poor differentiated subgroup, biopsy samples and high-level AD-TMs cases were more than those with high/moderate differentiation, surgical specimens and normal-level AD-TMs. Moreover, biopsy sample was a significant factor decreasing diagnostic accuracy of pathological subtype (OR, 4.037; 95% CI 1.446-11.267, p=0.008). Additionally, EGFR mutation rate was higher in patients with pathological diagnostic changes than those with confirmed SQCC (16.7% vs 4.4%, p=0.157). Conclusions: Diagnosis based on HE staining only might cause pathological misinterpretation in NSCLC patients with poor differentiation or high-level AD-TMs, especially those with biopsy samples. HE staining and IHC should be combined as pathological diagnostic standard. The occurrence of EGFR mutations in pulmonary SQCC might be overestimated.

      • KCI등재

        Theoretical and experimental studies on the hydrodynamic damping of elastic rotating propeller blades

        Chen Hongyang,Tong Xiandong,Chen Yong,He Jingyi 대한조선학회 2022 International Journal of Naval Architecture and Oc Vol.14 No.1

        The hydrodynamic damping characteristics of elastic rotating propeller blades are investigated theoretically and experimentally. Firstly, the modal hydrodynamic damping ratio of propeller blade rotating in water is theoretically predicted based on the cantilever plate theory. Then, a series of tests are designed to determine the mechanical, acoustic radiation and hydrodynamic damping of the first-order bending mode of the rotating blade. During the hydrodynamic damping test, the bending vibration of the blade is excited by the rotation-induced turbulence and measured by two strain gauges attached to the blade root. The results show that the theoretical prediction is in good agreement with the experimental results. The hydrodynamic damping increases linearly with the rotational speed of the propeller. Theoretical analysis also shows that the modal hydrodynamic damping ratio of the first-order bending mode is much larger than that of higher-order bending modes. The hydrodynamic damping decays exponentially with the increase of frequency ratio while increases slightly with the increase of propeller advance ratio which represents the ratio of free stream fluid speed to the propeller tip speed.

      • SCOPUSKCI등재

        New Compounds from Euphorbia helioscopia and Absolute Configuration Determination by Computational Methods

        He, Jiang-Bo,Zhu, Hua-Jie,Luo, Gui-Fen,Liu, Guang-Ming,Chen, Hao,Li, Yan,Chen, Shaopeng,Lu, Xin,Zhou, Guochun,Cheng, Yong-Xian Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.8

        The whole plant of Euphorbia helioscopia is an important traditional Chinese medicine. Fom its BuOH soluble extract, one new lactam (1), three new terpenoids (2-4) including a new naturally occurring compound, and three known compounds were isolated. Their structures were identified by spectroscopic evidences. In particular, the absolute configurations of side chain of compounds 1 and 2 were determined using computational methods.

      • Ki-67 is a Valuable Prognostic Factor in Gliomas: Evidence from a Systematic Review and Meta-analysis

        Chen, Wen-Jie,He, De-Shen,Tang, Rui-Xue,Ren, Fang-Hui,Chen, Gang Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

        Ki-67 has been widely used as an indicator of cell proliferation in gliomas. However, the role of Ki-67 as a prognostic marker is still undefined. Thus, we conducted a meta-analysis of the published literatures in order to clarify the impact of Ki-67 on survival in glioma cases. Eligible studies were identified in PubMed, EMBASE, ISI Web of Science, Cochrane Central Register of Controlled Trials, Science Direct and Wiley Online Library with the last search updated on August 31, 2014. The clinical characteristics, overall survival (OS) and progression-free survival (PFS) together with Ki-67 expression at different time points were extracted. A total of 51 studies, covering 4,307 patients, were included in the current meta-analysis. The results showed that overexpression of Ki-67 can predict poor OS (HR=1.66, 95%CI: 1.53-1.80; Z=11.87; p=0.000) and poor PFS (HR=1.67, 95%CI: 1.47-1.91; Z=7.67; p=0.000) in gliomas. Moreover, subgroup analyses also indicated that high level of Ki-67 expression was related to poor OS and PFS in glioma patients regardless of region, pathology type, cut-off value and statistical method. In conclusion, the current meta-analysis revealed that Ki-67 expression might be a predicative factor for poor prognosis of glioma patients, emphasizing its importance as a predictor.

      • KCI등재

        MR 유체 입자 속도 계측을 위한 디지털 홀로그래피 현미경 시스템의 개발

        ( He-peng Chen ),강보선 ( B. S. Kang ) 한국액체미립화학회 2016 한국액체미립화학회지 Vol.21 No.2

        In this study digital holographic microscopy system for measurements of 3-D velocities of particles in MR fluid is developed. Holograms are recorded using either a CCD camera with a double pulse laser or a high-speed camera with a continuous laser. To process recorded holograms, the correlation coefficient method is used for focal plane determination of particles. To remove noise and improve the quality of holograms and reconstructed images, a Wiener filter is adopted. The two-threshold and image segmentation methods are used for binary image transformation. For particle pairing, the match probability method is adopted. The developed system will be applied to measurements of the characteristics of unsteady 3- D particle velocities in MR fluids through the next stage of this study.

      • Thermostability of Monolithic and Reinforced Al-Fe-V-Si Materials

        He, Yiqiang,Qiao, Bin,Wang, Na,Yang, Jianming,Xu, Zhengkun,Chen, Zhenhua,Chen, Zhigang The Korean Society for Composite Materials 2009 Advanced composite materials Vol.18 No.4

        Al-Fe-V-Si alloys reinforced with SiC particles were prepared by multi-layer spray deposition technique. Both microstructures and mechanical properties including hardness and tensile properties development during hot exposure process of Al-8.5Fe-1.3V-1.7Si, Al-8.5Fe-1.3V-1.7Si/15 vol% $SiC_P$ and Al-10.0Fe-1.3V-2Si/15 vol% $SiC_P$ were investigated. The experimental results showed that an amorphous interface of about 3 nm in thickness formed between SiC particles and the matrix. SiC particles injected silicon into the matrix; thus an elevated silicon concentration was found around $\alpha-Al_{12}(Fe,\;V)_3Si$ dispersoids, which subsequently inhibited the coarsening and decomposition of $\alpha-Al_{12}(Fe,\;V)_3Si$ dispersoids and enhanced the thermostability of the alloy matrix. Moreover, the thermostability of microstructure and mechanical properties of Al-10.0Fe-1.3V-2Si/15 vol% $SiC_P$ are of higher quality than those of Al-8.5Fe-1.3V-1.7Si/15 vol% $SiC_P$.

      • SCOPUS

        A Continuous Abnormal Speech Detection Method Based on Time Domain features Weighted

        He Jun,Ji-chen Yang,Qing-hua Zhang,Guo-xi Sun,Jian-bing Xiong 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.12

        In this brief, a novel pathological continuous speech detection method based on time domain features weighted. First, different optimal threshold for time domain features, including zero crossing ratio, short-time energy and autocorrelation, are obtained from training speech data. Second, a difference evaluation technique is proposed, and with it, the difference of the same time domain feature selected from testing speech data and training speech data were obtained. Finally, to distinguish a given speech well, a novel weighting method based on difference evaluation for each kinds of time domain is employed, respectively. Experiments were conducted on the pathological speech database to prove the power and effectiveness of the proposed method. Results obtained shown that this method outperforms other early proposed time domain feature method, creating a more reliable technique for pathological continuous speech detection.

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