Experimental Study on Bond Behavior between Section Steel and RAC under Full Replacement Ratio

Chao Liu,Ziyu Fan,Xiaona Chen,Chao Zhu,Haiyang Wang,Guoliang Bai 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.3

Nine specimens of steel reinforced recycled concrete are designed to explore the effect of four factors as the cover thickness of section steel, the embedded length of section steel, the recycled aggregate concrete strength, and the lateral stirrup ratio on bond slip between section steel and recycled aggregate concrete. The test results show that the failure modes of recycled aggregate concrete are as similar as normal concrete; three formulas are proposed for the bond stress between section steel and recycled aggregate concrete, which are fitting well. The mathematical model of bond stress-slip is established through analysis, and the predicted curve is close to the test curve. The research results provide the basis for the numerical simulation analysis of the bond slip for the recycled aggregate concrete under the full replacement ratio.

An Intelligent Nano-positioning Control System Driven by an Ultrasonic Motor

Fan, Kuang-Chao,Lai, Zi-Fa Korean Society for Precision Engineering 2008 International Journal of Precision Engineering and Vol.9 No.3

This paper presents a linear positioning system and its control algorithm design with nano accuracy/resolution. The basic linear stage structure is driven by an ultrasonic motor and its displacement feedback is detected by a LDGI (Laser Diffraction Grating Interferometer), which can achieve nanometer resolution. Due to the friction driving property of the ultrasonic motor, the driving situation differs in various ranges along the travel. Experiments have been carried out in order to observe and realize the phenomena of the three main driving modes: AC mode (for mm motion), Gate mode (for ${\mu}m$ motion), and DC mode (for nm motion). A proposed FCMAC (Fuzzy Cerebella Model Articulation Controller) control algorithm is implemented for manipulating and predicting the velocity variation during the motion of each mode respectively. The PCbased integral positioning system is built up with a NI DAQ Device by a BCB (Borland $C^{++}$ Builder) program to accomplish the purpose of an intelligent nanopositioning control.

중국 태권도 수련자의 관여도와 한국의 국가이미지 및 한국 제품 구매의도의 구조적 관계

Fan Chao,조광민(Kwang Min Cho),원도연(Do Yeon Won) 한국사회체육학회 2013 한국사회체육학회지 Vol.0 No.53

The purpose of this study was to investigate the relationship among the involvement of Chinese Taekwondo trainers, Korea national image, and Korean products purchase intention. Total 568 participants were collected or analyses. The verification of model suitability and research hypotheses were tested by confirmatory factor analysis (CFA) and structural equation model (SEM). The results of current study were as following: First, the involvement of Chinese Taekwondo trainers has significant effect to Korean national image. Second, Korean national image has significant effect to Korean products purchase intention. Third, involvement of Chinese Taekwondo trainers has significant effect to Korean products purchase intention.

Computational study on the performance improvement of axial-flow pump by inlet guide vanes at part loads

Fan Yang,Wen-zhu Hu,Chao Li,Chao Liu,Yanjing Su 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.12

In order to investigate the influence of adjustable inlet guide vanes on the hydraulic performance of axial-flow pump and impeller, the axial-flow pump with different inlet guide vane adjustable angles was simulated based on the RNG k-ε turbulent model and Reynolds time-averaged equations. The multivariate non-linear regression prediction model was established about the effect of adjustable inlet guide vane on the hydraulic performance of axial-flow pump based on the numerical simulation. The performance curves of axial-flow pump with different inlet guide vane adjustable angles were obtained by calculation, showing that the performance curve shifts towards larger flow volume in case the guide vanes are turned from positive to negative angle. With the increase of inlet guide vane positive angle, the optimum operating of pump is closer to smaller operating condition, but the hydraulic efficiency of pump is lower. The larger the flow is, the larger the decreasing amplitude of pump efficiency is. With the decreases of inlet guide vane negative angle, the higher hydraulic efficiency of pump increases first then decreases. The inlet guide vane angle affects the axial velocity distribution of the blade trailing edge.

Development of a High Precision Coplanar Stage by using Miniature Michelson Interferometer

Kuang-Chao Fan,Hao Zhou,Ruijun Li 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

The motion control of a high precision coplanar XY-stage is very important to the performance of the nano-positioning control system. A prototype micro-coordinate measuring machine (Micro-CMM) has been developed by the authors’ group. This system is constructedby a high precision coplanar stage that conforms to Abbe principle, a Z-ram equipped with a touch scan probe and mounted on apagoda bridge. In this paper, an improved coplanar stage is presented. The miniature laser interferometer based on Michelsonprinciple is developed for precise displacement feedback in each axis and the software for the coplanar stage based on BPNN (BackPropagation Neural Network) in association with the PID control has been developed. Experiment results show that, calibrated bya commercial laser interferometer, the positioning accuracy is proved within 20 nm with a standard deviation less than 15 nm forthe travel length of 20 mm.

중국의 문화교류 증진을 위한 거버넌스 기능 분석

이초범(Chao Fan Li),황인영(Inyoung Hwang),이종열(Jong-youl Lee) 한국문화정책학회 2015 문화정책 Vol.2 No.2

21세기 글로벌 환경에서 국가 간의 교류는 점점 더 빈번해지고 있으며 그 분야와 다양성은 날로 확대되고 있다. 그 중 문화교류는 다른 분야의 교류를 견인하고 있다. 현재 중국은 경제발전에서 나아가 자국의 우수한 문화유산을 발전시키고 이를 전 세계에 알려 중국의 국가브랜드를 높이고자 애쓰고 있다. 본 논문은 중국 문화교류 거버넌스의 기능을 분석하고 그 특징을 파악하여 향후 중국의 문화교류 활성화에 기여하고자 한다. 중국 문화교류 거버넌스 참여주체는 크게 중앙정부, 지방정부, 민간단체로 구분되며, 각 주체들은 대내외적으로 서로 다른 역할을 하고 있다. 중국은 다양한 거버넌스 참여주체들을 통해 거버넌스 체계를 발전시키고 있다. 현재 거버넌스 체계에서 각 참여주체들의 역량을 강화하고 협력관계의 기능을 보완한다면 중국의 문화교류는 더욱 전세계적으로 증진될 것으로 기대된다. Exchanges among nations become frequent and subject and diversity of exchange is expanded in the 21st century global environment. Cultural exchanges leads exchanges of other fields. China makes an great effort to enhance national brands by developing excellent cultural heritage and introducing it to the world. This paper is to contribute to the promotion of China"s cultural exchanges in the future by analyzing the functions of China"s cultural exchanges governance and identify its characteristics. Participants in the cultural exchanges governance of China are largely divided into central government, local governments and private organizations and each participant takes different roles domestic and foreign aspects. China is developing the cultural exchanges governance system through the fostering various participants. Cultural exchange of china is expected to be promoted by strengthening the competence of participants and complementing the functions of cooperative relationships.

YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor–Induced Activation of the PI3K Pathway

Wang, Chao,Gu, Chao,Jeong, Kang Jin,Zhang, Dong,Guo, Wei,Lu, Yiling,Ju, Zhenlin,Panupinthu, Nattapon,Yang, Ji Yeon,Gagea, Mihai (Mike),Ng, Patrick Kwok Shing,Zhang, Fan,Mills, Gordon B. American Association for Cancer Research 2017 Cancer Research Vol.77 No.7

<P>Interactions between HIPPO, YAP/TAZ, and the PI3K/AKT pathway may be therapeutically targetable, providing new approaches to treating endometrial cancers and other cancers where the HIPPO pathway is a core oncogenic driver.</P><P>The transcription regulators YAP and TAZ function as effectors of the HIPPO signaling cascade, critical for organismal development, cell growth, and cellular reprogramming, and YAP/TAZ is commonly misregulated in human cancers. The precise mechanism by which aberrant YAP/TAZ promotes tumor growth remains unclear. The HIPPO tumor suppressor pathway phosphorylates YAP and TAZ, resulting in cytosolic sequestration with subsequent degradation. Here, we report that the PI3K/AKT pathway, which is critically involved in the pathophysiology of endometrial cancer, interacts with the HIPPO pathway at multiple levels. Strikingly, coordinate knockdown of YAP and TAZ, mimicking activation of the HIPPO pathway, markedly decreased both constitutive and growth factor–induced PI3K pathway activation by decreasing levels of the GAB2 linker molecule in endometrial cancer lines. Furthermore, targeting YAP/TAZ decreased endometrial cancer tumor growth <I>in vivo</I>. In addition, YAP and TAZ total and phosphoprotein levels correlated with clinical characteristics and outcomes in endometrial cancer. Thus, YAP and TAZ, which are inhibited by the HIPPO tumor suppressor pathway, modify PI3K/AKT pathway signaling in endometrial cancer. The cross-talk between these key pathways identifies potential new biomarkers and therapeutic targets in endometrial cancer. <I>Cancer Res; 77(7); 1637–48. ©2017 AACR</I>.</P>

An Intelligent Nano-positioning Control System Driven by an Ultrasonic Motor

Kuang-Chao Fan,Zi-Fa Lai 한국정밀공학회 2008 International Journal of Precision Engineering and Vol.9 No.3

This paper presents a linear positioning system and its control algorithm design with nano accuracy/resolution. The basic linear stage structure is driven by an ultrasonic motor and its displacement feedback is detected by a LDGI(Laser Diffraction Grating Interferometer), which can achieve nanometer resolution. Due to the friction driving property of the ultrasonic motor, the driving situation differs in various ranges along the travel. Experiments have been carried out in order to observe and realize the phenomena of the three main driving modes: AC mode (for ㎜ motion), Gate mode (for ㎛ motion), and DC mode (for ㎚ motion). A proposed FCMAC(Fuzzy Cerebella Model Articulation Controller) control algorithm is implemented for manipulating and predicting the velocity variation during the motion of each mode respectively. The PCbased integral positioning system is built up with a NI DAQ Device by a BCB (Borland C?? Builder) program to accomplish the purpose of an intelligent nano-positioning control.

Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4

Liang, Chao-Fan,Liu, Jacky TC,Wang, Yu,Xu, Aimin,Vanhoutte, Paul M. American Heart Association, Inc. 2013 Arteriosclerosis, thrombosis, and vascular biology Vol.33 No.4

<P><B>Objective—</B></P><P>To analyze the role of toll-like receptor 4 in modulating metabolism and endothelial function.</P><P><B>Approach and Results—</B></P><P>Type 2 diabetic mice with mutated toll-like receptor 4 (DWM) were protected from hyperglycemia and hypertension, despite an increased body weight. Isometric tension was measured in arterial rings with endothelium. Relaxations to acetylcholine were blunted in aortae and mesenteric arteries of Lepr<SUP>db/db</SUP> mice, but not in DWM mice; the endothelial NO synthase dimer/monomer ratio and endothelial NO synthase phosphorylation levels were higher in DWM preparations. These differences were abolished by apocynin. Contractions to acetylcholine (in the presence of L-NAME) were larger in carotid arteries from Lepr<SUP>db/db</SUP> mice than from DWM mice and were inhibited by indomethacin and SC560, demonstrating involvement of cyclooxygenase-1. The release of 6-ketoprostaglandin F<SUB>1α</SUB> was lower in DWM mice arteries, implying lower cyclooxygenase-1 activity. Apocynin, manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, catalase, and diethyldithiocarbamate inhibited endothelium-dependent contractions. The mRNA and protein levels of NADPH oxidase isoforms NOX1 and NOX4 were downregulated in DWM mice arteries. The in vivo and in vitro administration of lipopolysaccharide caused endothelial dysfunction in the arteries of wild-type, but not toll-like receptor 4–mutated mice.</P><P><B>Conclusions—</B></P><P>Toll-like receptor 4 plays a key role in obesity and diabetes-associated endothelial dysfunction by increasing oxidative stress.</P>

Hollow Silicon Oxide Sphere Coated with Cuprous Oxide and Polyaniline as an Anode for High-Performance Lithium-Ion Batteries

Meiqiang Fan,Yong Jin Zou,Hao Yin,Yan Li Huang,Chengqiao Xi,Haixin Kang,Chao Li,Jingjing Zhang,Chunju Lv,Meiqiang Fan,Zhi Chen 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3

A hollow silicon oxide coated with cuprous oxide and polyaniline (hSiOx/Cu2O/PANI) was prepared via Stober method, magnesium reduction and chemical oxidative polymerization. The hSiOx/Cu2O/PANI (SiOx 62 wt.%, PANI 33 wt.%, Cu2O 5 wt.%) presented charge/discharge capacities of up to 2000 mAhg -1 after 60 cycles at 0.2 Ag -1 current density and higher than 880 mAhg -1 at 8 Ag -1 current density. Microstructural analysis demonstrated that the improvement was due to the nanostructure of hollow SiOx sphere coated with Cu2O and PANI, which could release high stress caused by volume expansion during the lithiation/delithiation process and had little damage to electrode materials. Cycle voltammetry (CV) and electrochemical impedance spectroscopy (EIS) results further confirmed that Cu2O and PANI dual-coating improved reversibility and conductivity of hSiOx and prevented it to drop from the electrode surface.