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      • 건축 프로젝트 적정 설계변경 관리를 위한 사례조사

        김성욱(Kim Sung-Wook),남혜원(Nam Hye-Won),이종식(Lee Jong-Sik),신창현(Shin Chang-Hyun),전재열(Chun Jae-Youl) 대한건축학회 2009 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.29 No.1(구조계)

        Recent design changes in the existing research on the factors and issues of design changes and analysis, responsible for analyzing the relationship, procedural issues, and issues of research that can be active. However, changes in the design of problems are essentially designed to complement the book is for the procedure. Methodology for dealing with design changes in the characteristics of the country and to reflect more realistically, and various design changes and looked at trends in related research. the design Change of this study to examine the domestic status and problems, identify the status of the country about the design changes, and in suggesting the direction to the development of the design changes.

      • KCI등재

        걷기운동과 조깅운동의 지질대사 변화에 관한 분석

        장영금(Young Kum Chang),임식(Sik Lim) 한국사회체육학회 2001 한국사회체육학회지 Vol.16 No.-

        The purpose of this study was to examine the impact of regular exercise on the change of lipids. Three groups were organized, which included a control group, a walking group and a jogging group. The latter two groups were asked to get no extra exercise. By type of exercise, the experimental group was divided into two subgroups: walking and jogging. The mean heart rate per minute was maintained at 40%HRmax(±5%) in the walking group and at 70°%HRmax(±5%) in the jogging group. Both groups walked or run separately for 30 minutes at a regular pace. The pretest was conducted before the experiment, and posttest was implemented twice, 8 and 12 weeks after the experiment. The lipids was measured while they were relaxed. The variables to be observed were total-cholesterol, triglyceride, HDL-C and LDL-C. As a result of analyzing the collected data, the following findings were given: 1. There was no significant lipids change when they were at ease after getting incremental loading exercise. So the incremental loading exercise didn`t affect lipids change during relaxation. 2. The two types of incremental loading exercise brought a different change, to lipids 8 weeks after the groups started exercising. Especially, the jogging group showed most increase or decrease, which showed jogging, one of high-intensive exercises, was more effective. 3. Exercise 12 weeks after, it`s found that not only type of exercise but exercise term made a difference to lipids change. In both walking and jogging groups, lipids change was more significant after 12-week exercise than 8-week one. This fact suggested that higher-intensive (jogging) and longer-term(12 weeks) regular exercise was more effective. 4. The control group showed no significant difference in lipids change after getting incremental loading exercise during different terms. Therefore, it could be said that incremental loading exercise didn`t have any influence, unless it`s done on a regular basis. 5. The lipids change of the walking group was more significant after 8- and 12-week exercise than at ease, except HDL-C. This implied HDL-C could increase after walking exercise for more than 8 weeks at least. So a regular exercise with an intensity equivalent to or higher than that of walking would produce a good result. 6. For the jogging group, HDL-C also increased more significantly after 12-week exercise than after 8-week one. As a regular exercise for 12 weeks or more exerted a significant impact on lipids change, a high-intensive and long-term exercise turned out more effective. In the jogging group, there was a significant lipids decrease among pretest, 8-week after posttest, and 12-week after posttest. And there also was a significant lipids decrease, except HDL-C, between 8-week exercise and 12-week one. Accordingly, a regular exercise for 8 weeks or more at least could serve to reduce cholesterol.

      • Correlation between skeletal and dental changes after mandibular setback surgery-first orthodontic treatment

        Chang-Hoon Rhee,Youn-Kyung Choi,Yong-Il Kim,Seong-Sik Kim,Soo-Byung Park,Woo-Sung Son 대한치과교정학회 2015 대한치과교정학회지 Vol.45 No.2

        Objective: To investigate skeletal and dental changes after application of a mandibular setback surgery-first orthodontic treatment approach in cases of skeletal Class III malocclusion. Methods: A retrospective study of 34 patients (23 men, 11 women; mean age, 26.2 ± 6.6 years) with skeletal Class III deformities, who underwent surgery-first orthodontic treatment, was conducted. Skeletal landmarks in the maxilla and mandible at three time points, pre-treatment (T0), immediate-postoperative (T1), and post-treatment (T2), were analyzed using cone-beam computed tomography (CBCT)-generated half-cephalograms. Results: The significant T0 to T1 mandibular changes occurred ?9.24 ± 3.97 mm horizontally. From T1 to T2, the mandible tended to move forward 1.22 ± 2.02 mm, while the condylar position (Cd to Po-perpendicular plane) shifted backward, and the coronoid process (Cp to FH plane) moved vertically. Between T1 and T2, the vertical dimension changed significantly (p < 0.05). Changes in the vertical dimension were significantly correlated to T1 to T2 changes in the Cd to Po-perpendicular plane (r = ?0.671, p = 0.034), and in the Cp to FH plane (r = 0.733, p = 0.016), as well as to T0 to T1 changes in the Cp to Poperpendicular plane (r = 0.758, p = 0.011). Conclusions: Greater alterations in the vertical dimension caused larger post-treatment (T2) stage skeletal changes. Studying the mandibular position in relation to the post-surgical vertical dimension emphasized the integral importance of vertical dimension control and proximal segment management to the success of surgery-first orthodontic treatment.

      • Aflatoxin B_1 투여가 急性 肝 病變에 미치는 영향에 對한 病理學的 硏究

        장선문,이충식,강대영 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

        In an attempt of elucidate the pathologic and histochemical changes of aflatoxin B_2-induced hepatie lesions, the present study in male Sprague-Dawley rats was undertaken to evalute the relation between pathologic change of the liver and histochemical changes of several enzymes : alkaline phosphatase, acid phosphatase and succinic dehydrogenase at 3. 9. 24. 48. 72, and 144 hours after single administration of aflatoxin B_1 by gastric tube. The aflatoxin B_1 was dissolved in peanut oil(0.5㎎ aflatoxin B_1 to 0.5ml peanut oil). Grouop of male rats received aflatoxin B_1 1㎎ per ㎏ of body weight, respectively. Control animals were given a similar volume of peanut oil alone. The results on morphologic and histochemical changes were as follows: 1. The necrotic change of liver was mainly periportal, and it became most severe at 24 hours and was more prominent in the large dose group than the small dose group. 2. Biliary ductular cell proliferation started to appear within 72 hours and after became regressed later in the small dose group, but it remained approximately 144 hours after exposure in the large dose group. 3. Electron microscopically, all three groups showed irregular nuclear membrane and nucleolar change characterized by segregation of granular and fibrillar elements. All the group showed cytoplasmie changes such as dilatation of rough endoplasmic reticulum with detached ribosome, hyperplasia of smooth endoplasmic reticulum, increased numbers of lipid droplets and mitochondrial alteration. The above change in the large dose group was more severe than those of the small dose group. 4. In the histochemical study of experimental animals, there was a decrease in the intensity of the staining reaction of alkaline phosphatase and succinic dehydrogenase within 24 hours and a progressive decrease in staining intensity was noted at 144 hours. And then the staining intensity of the acid phosphatase was similar to that shown by the control animal. In summary, the data obtained by present experiments indicate aflatoxin B_1 exerts periportal necrosis of hepatic lobules accompanied by bile ductular cell proliferation, and inhibition of protein synthesis, as jedged by elertron microscopic and histochemical changes.

      • SCIESCOPUSKCI등재
      • 평행봉 몸 굽혀 2회전 뒤 공중 돌아 내리기 동작의 국면별 운동학적 분석

        윤창선,강대식 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

        This thesis has an aim to examine the influence on landing of successful salto by the difference of athletic factors of salto backward tucked dismount on the parallel bars. This thesis analyzed six national representative players dividing them into the skill group (G1) who got more than 9.5 point and the unskilled group (G2) who got less than 9.5 point based on the average point by four international referees utilizing three dimensional image analyses photographed with video camera, and it got the conclusion of the athletic factors dividing into each aspect as followings. 1. As for the time spent by the groups when the thesis divided them into each aspect, G1 spent more time than G2. It's because G1 acted in stability at the moment of staying in the space and landing as it spent much time in the space with fast down swing and release, but G2 on the contrary, acted fast at the moment of space of four aspects with slow down swing and release. And its landing was unstable at the movement of low height. 2. As for the positional change in each aspect, the parallel position of G2 increased than that of G1, and the increased parallel position made the unstable salto and landing . As for the change of vertical position, at the time of down swing in the first aspect, what G1 acted at the low position of the second aspect at the high position seemed to be an act to release fast falling the high joint down, and it made salto high and made landing stable. 3. As for speed change of high joint in each aspect, G1 acted with fast horizontal speed generally at the time of release, aspect of space, and aspect of landing because of right horizontal speed at the time of down swing, and it seemed to be an act to get rotary power of double salto. As for the vertical speed, G1 acted with a much more vertical speed than G2 in four aspects with a big up-down movement by the fast vertical speed at the time of down swing and release. It means that G1 acted fast with a fast vertical speed of the high joint to get the height to stay in the air. 4. As for the change of the angle of the high joint in each aspect, G1 acted a bigger down swing and release than G2 utilizing the stretched body of the high joint at the time of down swing and release. As for change of angle of shoulder, G1 acted down swing with the shoulder joint accessed nearer than G2 to the body. At the time of down swing, it acted with a big angle of shoulder joint to stretch high shoulder at the time of swing. In addition to it, at the time of release, G2 escaped from the hand more slowly than G1 because of big angle. It made the movement of space and landing movement unstable. 5. As for change of angular speed in each aspect, G1 acted with a fast high joint down swing from the start to the first aspect. It acted with a slow speed of the angle stretching the high joint in the second and the third aspect so that it could get fast angular speed in the forth and the fifth aspect. As for the change of shoulder joint, G1 acted with a fast angular speed in the aspect of space and that of landing movement by the fast speed of shoulder joint at the time of release. In addition to it, fast angular speed of the shoulder joint in the release aspect of space made the rotary power of double salto.

      • Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

      • 체육교과 평가방식에 대한 소비자 의견 분석

        모창배,유인영,김정식 청주대학교 학술연구소 2004 淸大學術論集 Vol.2 No.-

        To collect customers opinion about physical education estimation system, this study targeted on 3rd grade students at academic high schools in Cheongju-city and Chungju-city in Chungcheongbuk-do. Main subjects of the study are each 4 classes in boys high school and girls high school. This paper examines the feasibility of estimation system change in the result of collecting customers opinion about estimation factors like reflection of school record and change, time factors like time obstacle and exercise ability, ability factors like influence and contents of school record, result factors like fairness of estimation, course factors like necessary and value of estimation and academic factors like private education expenses and its reduction. Based on the above result, it analyzes certification and correlation by item, sex and factor focused on every factor. Study materials are managed by SAS Package(Window Ver. 6.11). In the result of correcting customers opinion about the above estimation system, it shows as follows: First, it showed the difference by sex in change and reflection of physical education estimation system, change and influence of school record and necessary and value of estimation contents. Second, many male students supported items about exception and reflection of school record in physical education. It showed that most of students asked to change estimation system. Third, it showed time obstacle by students exercise ability in physical education estimation system. Male students have more obstacles to study other subjects than female ones. Fourth, it showed that many students asked to change estimation system not by influence of school record but by exercise ability. Fifth, it showed that many students emphasized fairness in estimation results by teachers. Sixth, in the case of male students, they asked enjoy activity and in the case of female ones, they asked physical development and health maintenance. Most students replied that physical education is necessary subject regardless of estimation. Seventh, Most students replied that physical education estimation system is not cause of increasing private education expenses directly. Eighth, students at academic high school have much correlation with estimation, time, ability, result and academic factor. On the other hand, it showed that subject factor did not much correlation with other factors.

      • GIS기법과 기후변화시나리오를 이용한 극한 강우에 따른 재해 영향성 평가

        함창학(Hahm, Chang Hahk),김병식(Kim, Byung-Sik) 한국측량학회 2012 한국측량학회 학술대회자료집 Vol.2012 No.4

        There has been growing the damage in an urban area on account of recent climate change. As the complicated type of damages such as domestic flooding, landslide overflow of rivers etc., has been emerged, great attention has been shown to the question of extreme precipitation, local downpour. Under confined spaces and limited resources, we should selectively take appropriate counterplan on flood disaster in accordance with the climate change. For decision making, we should consider the estimation of disaster according to extreme precipitation affected by climate change. Simulating the daily rainfall in the future (2001-2100) by using SRES A2 scenarios and high-resolution RCM model, we estimated EVI(Extreme Volatility Index), HRI(Human Risk Index), and DII(Disaster Impact Index). Then, we finally evaluated the effect of occurrence of extreme precipitation in future climate change through comparison and analysis on spatio-temporal distribution of the Korean Peninsula. The conclusion which can be drawn from study are these: 1) Extreme Volatility Index loomed large in Gyeongsang-do and Jeolla-do, 2) Human Risk Index has largely revealed 7 metropolitan city and national capital region, and 3) Area located on the border of the whole area on the West Coast , Gyeongsang-do and Jeolla-do have large Disaster Impact Index. In short, these areas will be influenced by flood disaster in accordance with the future climate change.

      • KCI등재

        Association of Change in Smoking Status and Subsequent Weight Change with Risk of Nonalcoholic Fatty Liver Disease

        Jeong Seogsong,Oh Yun Hwan,Choi Seulggie,Chang Jooyoung,Kim Sung Min,Park Sun Jae,Cho Yoosun,Son Joung Sik,Lee Gyeongsil,Park Sang Min 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.1

        Background/Aims: Smoking is considered a risk factor for the development of nonalcoholic fatty liver disease (NAFLD). However, the association of a weight change after a change in smoking status and the risk of NAFLD remains undetermined. Methods: This study used the Korean National Health Insurance Service-National Sample Cohort. Based on the first (2009 to 2010) and second (2011 to 2012) health examination periods, 139,180 adults aged at least 40 years were divided into nonsmoking, smoking cessation, smoking relapse, and sustained smoking groups. NAFLD was operationally defined using the fatty liver index. The adjusted odds ratio (aOR) and 95% confidence interval (CI) were calculated using multivariable-adjusted logistic regression. Results: Compared to nonsmoking with no body mass index (BMI) change, the risk of NAFLD was significantly increased among subjects with BMI gain and nonsmoking (aOR, 4.07; 95% CI, 3.77 to 4.39), smoking cessation (aOR, 5.52; 95% CI, 4.12 to 7.40), smoking relapse (aOR, 7.51; 95% CI, 4.81 to 11.72), and sustained smoking (aOR, 6.65; 95% CI, 5.33 to 8.29), whereas the risk of NAFLD was reduced among participants with BMI loss in all smoking status groups. In addition, smoking cessation (aOR, 1.76; 95% CI, 1.35 to 2.29) and sustained smoking (aOR, 1.64; 95% CI, 1.39 to 1.94) were associated with higher risk of NAFLD among participants with no BMI change. The liver enzyme levels were higher among participants with smoking cessation and BMI gain. Conclusions: Monitoring and management of weight change after a change in smoking status may be a promising approach to reducing NAFLD.

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