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Chang-Won Im,Wan-Kyu Lee 한국예방수의학회 2021 예방수의학회지 Vol.45 No.3
The abnormal meat could caused by abscess, fibrosis and granuloma in the region of the neck by the adverse effect of foot-and-mouth disease (FMD) vaccination practice for Korean swine. After FMD vaccination was implemented in 2010, the number of incidences of abnormal meat has been increasing. In this study, it was evaluated whether needless intradermal injection (NII) of FMD vaccine reduces abnormal meat at the injection site in comparison to conventional intramuscular injection (IM). In addition, the onset of humoral immunity was analyzed in order to see if NII of this vaccine is able to mount comparable antibody response with IM. This study was carried out in four Korean pig farms. The O-type FMD vaccine was implemented via NII at three farms and the control group was vaccinated via IM. Antibody titers were compared from the serum samples taken from 10 random pigs at age of 8, 12, 16 and 22~24 weeks of age. The O+A type FMD vaccine was also compared with the same protocol. When test animals were slaughtered, incidence, type and size of abnormal meat were recorded. The results of this study showed that the antibody titers between intradermal and intramuscular group were similar but a significant difference in the incidence of abnormal meat formation was observed between two groups (p < 0.05). In summary, needless intradermal injection of FMD vaccination was proven to be effective for the onset of humoral immunity and reducing abnormal meat formation.

농촌지역 여성고령자의 현미덤벨체조가 체조성, 체력 및 식습관에 미치는 영향
이기철 ( Lee Gi Cheol ),정창주 ( Jeong Chang Ju ),손기수 ( Son Gi Su ),우임수 ( U Im Su ),이원경 ( Lee Won Gyeong ),공무현 ( Gong Mu Hyeon ),이수천 ( Lee Su Cheon ) 한국운동영양학회 2003 Physical Activity and Nutrition (Phys Act Nutr) Vol.7 No.2
The present study evaluated the possibility of dumbbell exercise as to improve the physical fitness and the health starus of old people in rural area. Although eighty seven volunteers of old women (over 64) living in Seonsan, Gumi city were subjected, twenty of them were attended the whole program for 6 months and the data from the twenty was analysed in this study. The results were drawn out from comparison of the body constitutuion, the physical strength, the medical aspectrs, and the questionaires of before and after this program. They showed increased physical fithess tested by grip strength (left), bar gripping reaction time, standing trunk flexibility, on foot standing test through dumbbell exercise for 6 months. Questionaire revealed the betterment of dietary pattem during this program. In the light of in these results, it is possible to conclude that dumbbell exercise had improved the basic physical condition and the health status through the increasement of physical fitness and dietary pattem change. Therefore, dumbbell exercise would be a useful program for the old people in reual area to improved their health status.
A preliminary study in melasma following INMODE forma procedure
( Soon-hyo Kwon ),( Je-byeong Chae ),( Jung-won Shin ),( Jung-im Na ),( Chang-hun Huh ),( Kyoung-chan Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Melasma is a common hypermelanosis that frequently appears on the face. In recent studies, it is suggested that dermal structural alteration, including solar elastosis and basement membrane disruption, may have an important role in the pathogenesis of melasma. Forma device (InMode Inc, Richmond Hill, ON, Canada, North America) is a radiofrequency dermal heating device used on facial wrinkles and rhytides. Objectives: The aim of this study was to evaluate the effects of Forma device on melasma in a small group of volunteers. Methods: All volunteers were treated 4 times at 3 weeks intervals. Every visit, melanin index and erythema index was measured to assess the improvement in hyperpigmentation and erythema. Clinical photos were evaluated to estimate the degree of skin changes. Results: Clinical and instrumental evaluation showed that melasma improved after INMODE forma treatment. Conclusion: We suggest that treatment with Forma device may have beneficial effects on melasma by dermal remodeling and direct heat delivery on melanocytes.
우황청심원 관련 최근 연구 동향 : 국내 논문에 대한 고찰
이제원,백경민,백영두,임은영,장우석,전우현,정인권,Lee, Je-Won,Baek, Kyung-Min,Baek, Young-Doo,Im, Eun-Young,Chang, Woo-Seok,Cheon, Woo-Hyun,Chung, In-Kwon 대한한방내과학회 2010 대한한방내과학회지 Vol.31 No.4
Objectives : Woohwangchungsim-won has been used for acute diseases such as cerebrovascular disease (stroke), heart disease. The aim of this study was to determine the effects, significance & necessity of Woohwangchungsim-won in acute stages of these disease by reviewing Korean articles about Woohwangchungsim-won. Methods : Article searches were performed on 8 major Korean web article search engine from January 1980 to August 2010. There were no restrictions on the types of publication, including grey articles. Results : Forty-three articles were included. Twenty one were efficacy tests, thirteen were comparative efficacy tests, eight were toxicity tests, and one was new method development. Eighteen articles were multicenter studies and twenty five were single center studies. Thirty two articles were animal testing, only ten articles were clinical articles. Thirty seven articles presented the composition and quantity of Woohwangchungsim-won, but six did not. Conclusions : The results of Korean articles about Woohwangchungsim-won can not strongly support the effects, significance & necessity of Woohwangchungsim-won. More rigorous studies are required for determination of the effects of Woohwangchungsim-won.

Prevalence of fecal bacterial pathogens in diarrheic piglets in the Republic of Korea (2023-2024)
Chang-Won Im, Doo-Sung Cheon, Ki-Hong Park, Young-Ho Joo, Wan-Kyu Lee 한국예방수의학회 2025 예방수의학회지 Vol.49 No.4
Enterotoxigenic Escherichia coli (ETEC) and Clostridium perfringens are key pathogens responsible for neonatal and post-weaning diarrhea, causing notable morbidity, mortality, and economic loss worldwide. However, nationwide data on bacterial pathogens causing piglet diarrhea in Korea remain limited. This study aimed to determine the prevalence and distribution of E. coli fimbrial and toxin genes, C. perfringens, and Clostridioides difficile in diarrheic piglets in Korea (2023-2024). Overall, 1,339 fecal samples were collected from diarrheic piglets across Korean pig farms. Species-specific virulence genes were detected using real-time polymerase chain reaction assay targeting major fimbrial and toxin factors of E. coli, C. perfringens (CPA), and C. difficile (TcdA/TcdB). Prevalence was compared across years and seasons. Among E. coli fimbrial factors, F18 (17.0%), F4 (7.4%), and F17 (4.7%) were common, whereas F5, F6, and F41 were rare (<3%). STb (30.1%) and STa (21.1%) were common, and Stx2e prevalence increased from 6.8% to 13.4% (p < 0.001). LT was detected in 9.0% of cases; C. perfringens in 22.3% of cases, increasing from 17.9% to 27.4% (p < 0.001); and C. difficile in 7.7% of cases. Several pathogens showed quarterly variations, with F4 and STa peaking in Q1 (January-March), STb in Q3 (July-September), and C. perfringens showing higher detection rates in Q1 and Q4 (October-December). ETEC-associated fimbrial and toxin genes, particularly F18/F4 and STa/STb, remained the most frequently detected among diarrheic piglets in Korea, with Stx2e and C. perfringens also playing important roles. These findings highlight the multifactorial nature of piglet diarrhea and the need for continuous nationwide surveillance and integrated prevention strategies.
Im, Junhyuck,Seoung, Donghoon,Hwang, Gil Chan,Jun, Jong Won,Jhung, Sung Hwa,Kao, Chi-Chang,Vogt, Thomas,Lee, Yongjae American Chemical Society 2016 Chemistry of materials Vol.28 No.15
<P>Pressure-dependent structural and chemical changes of the metal organic framework (MOF) compound MIL-47(V) have been investigated up to 3 GPa using different pore-penetrating liquids as pressure transmitting media (PTM). We find that at 0.3(1) GPa the terephthalic acid (TPA) template molecules located in the narrow channels of the as synthesized MIL-47(V) are selectively replaced by methanol molecules from a methanol ethanol water mixture and form a methanol inclusion complex. Further pressure increase leads to a gradual narrowing of the channels up to 1.9(1) GPa, where a second irreversible insertion of methanol molecules leads to more methanol molecules being inserted into the pores. After pressure release methanol molecules remain within the pores and can be removed only after heating to 400 degrees C. In contrast, when MIL-47(V) is compressed in water, a reversible replacement of the TPA by H2O molecules takes place near 1 GPa. The observed structural and chemical changes observed in MIL-47(V) demonstrate unique high pressure chemistry depending on the size and type of molecules present in the liquid PTM. This allows postsynthetic nonthermal pressure-induced removal and insertion of organic molecules in MOFs forming novel and stable phases at ambient conditions.</P>