Development of Instrument of Bullying Behaviors in Nursing Education based on Structured Equation Modeling

Kamuran Cerit,Sultan Türkmen Keskin,Dilek Ekici 한국간호과학회 2018 Asian Nursing Research Vol.12 No.4

Purpose: Bullying behaviors experienced during nursing education negatively affect students, educators, quality of training, and patient care. The purpose of this study was to develop a valid, reliable, short, and comprehensive scale to measure the bullying behaviors of nursing students in the education environment. Methods: The Bullying Behaviors in Nursing Education (BBNE) tool was developed by adapting the Workplace Psychological Violence Behaviors scale. The data were collected from 442 nursing students from April to May 2017. The BBNE was tested using structural equation modeling, and validity and reliability results were obtained. Moreover, complementary statistics were determined, and the violence behaviors experienced by nursing students were reported. Results: The full BBNE scale, with 30 items and four factors, was not verified (x2/df = 4.31); 12 items were excluded, and the modified structure with 18 items and four factors was verified (x2/df = 2.60; root-mean-square error of approximation = .06). The scale's Cronbach's a coefficient is .88, and the structure reliability is .92. Twenty-five percent of the 442 students scored 1 or higher in the total scale, showing that they were subject to bullying behaviors. Conclusion: The BBNE scale can be used to measure the bullying behaviors of nursing students in the education environment. When such behaviors are identified, students can struggle on the personal and organization level. Providing a safer and comfortable education environment for nursing students who are the guarantee of the future of health care will positively affect the quality of education and patient care in parallel.

Are Mannan-binding Lectine Serin Protease-2 and Alpha-1-microglobulin and Bukinin Precursor the Potential Biomarkers of Manic Episode? A Study via Urinary Proetomic Analysis

Cem Cerit,Mehmet Sarıhan,Ö,mer Nart,Murat Kasap,Hilmi Yaş,ar,Gü,rler Akpınar 대한정신약물학회 2021 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.19 No.2

Objective: Investigating the molecular basis of bipolar disorder (BD) is crucial in terms of developing effective treatment strategies as well as objective laboratory-based diagnostic tools for the disease. Methods: We examined the urine samples of BD patients both in manic episode and after remission and compared their urinary protein profiles with the controls. Twelve patients and twelve controls (C group) included to the study. Urinary samples of patients were first collected during manic episode (M group) and then after remission (R group). Two-dimensional gel electrophoresis (2-DE) coupled to MALDI-TOF/TOF massspectrometry approach and Western blot analysis were used. Results: Alpha-1-microglobulin and bukinin precursor (AMBP), Mannan-binding lectine serin protease-2 (MASP-2), and Ig gamma-1-chain displayed significant increases in their abundance in the urine protein pool of M group in comparison to the C and R groups. Alpha-1B glycoprotein and prostaglandin-H2 D-isomerase (PGD2) levels were significantly higher in the urine protein pool of the M and R groups in comparison to the C group. Annexin A1 was downregulated sig-nificantly in the urine protein pool of the M group in comparison to the C group. Conclusion: Intensities of MASP-2 and AMBP proteins discriminated manic episode from remission period and healthy controls indicating that these proteins may be candidate biomarkers for manic episode. The decrease in Annexin A1 and increase in Ig gamma-1 chain levels appeared to be associated with “Manic Episode” while the increase in PGD2 and alpha-1B glycoprotein levels appeared to be associated with “Bipolar Disorder”.

Is SYNTAX Score Predictive of Atrial Fibrillation after On-Pump Coronary Artery Bypass Graft Surgery?

Levent Cerit,Hamza Duygu,Kamil Gulsen,Hatice S Kemal,Barcın Ozcem,Ozlem Balcioglu,Aziz Gunsel,Ozgur Tosun,Volkan Emren 대한심장학회 2016 Korean Circulation Journal Vol.46 No.6

Background and Objectives: The relationship of synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score and development of atrial fibrillation (AF) after coronary artery bypass surgery (CABG) has not been studied. Therefore, we assessed the relationship between the SYNTAX score and development of AF after CABG (POAF). Subjects and Methods: The medical records of consecutive patients, who underwent CABG surgery from January 2013 to September 2015, were retrospectively reviewed for the development of AF in the postoperative period. SYNTAX score, clinical and echocardiographic parameters were evaluated. The independent variables for the development of POAF were defined and their predictive values were measured. Results: The study group consisted of 106 patients, of which 36 (34%) developed POAF. Age, hypertension, stroke, chronic obstructive pulmonary disease (COPD), heart failure (HF), diabetes mellitus (DM), left atrial diameter, neutrophil/lymphocyte ratio, platelet large cell ratio, creatinine, blood urea nitrogen and SYNTAX score were identified as important variables for the development of POAF. However, in logistic regression analysis COPD (OR=19.313, 95% CI=2.416-154.407, p=0.005), HF (OR=28.362, 95% CI=2.034-395.515, p=0.013), SYNTAX score (OR=0.863, 95% CI=0.757-0.983, p=0.026), and DM (OR=20.770, 95% CI=3.791-113.799, p<0.001) appeared as independent variables predicting the development of POAF. In receiver operation characteristic analysis, SYNTAX score (≥22.25) (AUC=0.777, 95% CI=0.676-0.877, p<0.001) was one of the strongest predictors for the development of POAF. Conclusion: The SYNTAX score level was independently associated with the development of AF after CABG.

Differences in Health Promoting Lifestyle Behavior of Health Management Students Based Upon Early Diagnosis Coverage in a Cancer Course

Ozveren, Husna,Cerit, Birgul,Ertop, Nesime Guzel Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Background: This is a descriptive study to determine whether coursework that is focused on early diagnosis in cancer makes a difference in self-reported health promoting lifestyle behavior of students who study health management. Materials and Methods: The population of the study consisted of a sample of 104 students enrolled in the Department of Health Management at the Faculty of Health in Kirikkale University in Turkey. Forty-eight students enrolled in a course called "Early Diagnosis of Cancer" and fifty-six did not take this course. Demographic information was collected and the "Health Promotion Life-Style Profile (HPLP)" was used to collect health promotion data. Frequency and descriptive statistics including one-way ANOVA, Mann-Whitney U test, Kruskal Wallis tests were used to evaluate data. Results: The HPLP mean score of the students was found to be $127.5{\pm}17.45$. The highest mean score was observed for self-fulfillment and health responsibility, while the lowest was for diet and exercise sub-scales. It was found that certain variables were effective in developing health promoting lifestyle behaviors such as choosing this job voluntarily, working status of father and participation in social activity (p<0.05). In conclusion, it was found that the students had moderate levels of health promoting lifestyle behavior and they should be supported in terms of diet and exercise.

Thermo mechanical analysis of a ceramic coated piston used in a diesel engine

Ekrem Buyukkaya,Muhammet Cerit,Mehmet Coban 국제구조공학회 2016 Steel and Composite Structures, An International J Vol.21 No.2

The aim of this paper is to determine temperature and stress distributions in a ceramic based on Partially Stabilized Zirconia coated steel piston crown by using plasma spraying for improving performance of a marine diesel engine. Effects of coating constituent and thickness on temperature and stress distributions were investigated including comparisons with results from an uncoated piston by means of finite element method namely ANSYS. Temperature developed at the coated surface is significantly higher than that of the uncoated piston. The maximum stress components occur between bond coat and adjacent ceramic layer. Provided that coating thickness is constant as 0.5 mm, when numbers of layers increase, magnitude of the normal stress decrease about 34.1% on the base metal surface according to uncoated piston, but the base metal surface temperature of the steel piston increase about 13.1%.

Agomelatine versus Sertraline: An Observational, Open-labeled and 12 Weeks Follow-up Study on Efficacy and Tolerability

Esma Akpınar,Cem Cerit,Anıl Talas,Ümit Tural 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.4

Objective: In this open-labeled, 12 weeks follow-up study, we aimed to compare the efficacy and tolerability of agomelatine with sertraline Methods: The outpatients of adult psychiatry clinic who have a new onset of depression and diagnosed as ‘major depressive episode’ by clinician according to the Diagnostic and Statistical Manual of Mental Disorders 4th edition and prescribed agomelatine (25 mg/day) or sertraline (50 mg/day) were included in the study. Results: The decline of mean Montgomery-Asberg Depression Rating Scale (MADRS) scores of agomelatine group was significantly higher than the sertraline group at the end of 2nd week; however, the difference was not significant at the end of 3 months. Mean Clinical Global Impression-Improvement scale (CGI-I) scores of agomelatine group was lower than sertraline group at first week. Mean CGI-Severity scale and CGI-I scores were favour to sertraline group at the end of the study. Remission rates were 46.7% for sertraline group and 33.3% for agomelatine group while response rates were 76.7% for both groups. Any patient from agomelatine group dropped-out due to adverse effects. The amount of side effects was also less with agomelatine. Conclusion: Agomelatine has a rapid onset efficacy on depressive symptoms and this can be beneficial for some critical cases. Considering MADRS scores, agomelatine seems to have similar efficacy with sertraline but we also point the need for long term studies since CGI scores were favour to sertraline group at the end of the study. Agomelatine has a favourable tolerability profile both in terms of discontinuation and the amount of side effects compared to sertraline.

Serum N-Desmethylcitalopram Concentrations are Associated with the Clinical Response to Citalopram of Patients with Major Depression

Gul Ozbey,Berna Yucel,Nurdan Eren Bodur,Serap Erdogan Taycan,Tayyibe Arslan,Nazan Cerit,Nevzat Yuksel,Ismail Cuneyt Guzey,Canan Uluoglu 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.3

Objective-Citalopram (CITA) is a widely used and well-tolerated selective serotonin reuptake inhibitor. The aim of the study was to evaluate the possible influences of serum concentrations of CITA and its major metabolite n-desmethylcitalopram (NDCITA) on the efficacy and tolerability of CITA in patients with major depressive disorder. Methods-The study included 46 outpatients with major depressive disorder who received CITA. The efficacy and tolerability were assessed for 6 weeks. Serum CITA and NDCITA levels were measured at the 4th week. Results-The HDRS17 total scores of the patients with high NDCITA and CITA & NDCITA concentrations showed a more significant reduction compared to the patients with expected and low serum NDCITA and CITA & NDCITA concentrations. However, we did not observe a correlation between the serum concentrations and the side effects of CITA, NDCITA, and CITA & NDCITA. Conclusion-Our results suggested the potential contribution of NDCITA to the antidepressant effect of CITA. Further studies involving larger clinical samples are required to confirm the impact of serum NDCITA concentrations on the efficacy of CITA.