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RISS 인기검색어
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Giant Multilocular Cystadenoma of the Prostate: A Rare Cause of Huge Cystic Pelvic Mass
Deniz Cebi Olgun,Bulent Onal,Ismail Mihmanli,Fatih Kantarci,Haydar Durak,Hale Demir,Bulent Cetinel1 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.3
Giant multilocular prostatic cystadenoma is a rare benign tumor that evolves from the prostate gland. Obstructive voiding symptoms occur in all reported cases. These lesions do not invade adjacent structures. Preoperative radiologic evaluation can define the benign nature of the lesion. Here we report a case of large cystic lesions identified by magnetic resonance imaging and sonographic findings that caused an extensive mass effect in the pelvis. When retrovesical, huge cystic lesions fill the pelvis completely in young men, with high levels of serum prostate-specific antigen, giant multilocular prostatic cystadenoma should be considered as a differential diagnosis. To our knowledge, this is the youngest case of prostatic cystadenoma reported in the literature.
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A Rare Cause of Recurrent Acute Pancreatitis in a Child: Isovaleric Acidemia with Novel Mutation
Sag, Elif,Cebi, Alper Han,Kaya, Gulay,Karaguzel, Gulay,Cakir, Murat The Korean Society of Pediatric Gastroenterology 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.1
Recurrent acute pancreatic attacks is a rare clinical condition (2-5% of all acute pancreatis) in children and is mainly idiopathic in most cases. Sometimes it may be associated with congenital anomalies, metabolic diseases or hereditary conditions. Isovaleric acidemia (IVA) is a rare autosomal recessive amino acid metabolism disorder associated with isovaleryl coenzyme A dehydrogenase deficiency presenting the clinical findings such metabolic acidosis with increased anion gap, hyperammonemia, ketonemia, hypoglycemia, "the odor of sweaty feet," abdominal pain, vomiting, feeding intolerance, shock and coma. Recurrent acute pancreatitis associated with IVA have been rarely reported. Herein; we report a child who admitted with recurrent acute pancreatic attacks and had the final diagnosis of IVA. Mutation analysis revealed a novel homozygous mutation of (p.E117K [c.349G>A]) in the IVA gene. Organic acidemias must kept in mind in the differential diagnosis of recurrent acute pancreatic attacks in children.
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A Rare Cause of Recurrent Acute Pancreatitis in a Child: Isovaleric Acidemia with Novel Mutation
Elif Sag,Alper Han Cebi,Gulay Kaya,Gulay Karaguzel,Murat Cakir 대한소아소화기영양학회 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.1
Recurrent acute pancreatic attacks is a rare clinical condition (2-5% of all acute pancreatis) in children and is mainly idiopathic in most cases. Sometimes it may be associated with congenital anomalies, metabolic diseases or heredi-tary conditions. Isovaleric acidemia (IVA) is a rare autosomal recessive amino acid metabolism disorder associated with isovaleryl coenzyme A dehydrogenase deficiency presenting the clinical findings such metabolic acidosis with increased anion gap, hyperammonemia, ketonemia, hypoglycemia, “the odor of sweaty feet,” abdominal pain, vomit-ing, feeding intolerance, shock and coma. Recurrent acute pancreatitis associated with IVA have been rarely reported. Herein; we report a child who admitted with recurrent acute pancreatic attacks and had the final diagnosis of IVA. Mutation analysis revealed a novel homozygous mutation of (p.E117K [c.349G>A]) in the IVA gene. Organic acidemias must kept in mind in the differential diagnosis of recurrent acute pancreatic attacks in children.
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Shear-Wave Elastography of Segmental Infarction of the Testis
Fatih Kantarci,Deniz Cebi Olgun,Ismail Mihmanli 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6
Segmental testicular infarction (STI) is a rare cause of acute scrotum. The spectrum of findings on gray-scale and color Doppler ultrasonography differ depending on the time between the onset of testicular pain and the ultrasonography examination. We are not aware of the usefulness of shear-wave elastography for the diagnosis of STI. We report the shear-wave elastography features in a case of STI and discuss the role of this diagnostic modality in the differential diagnosis.
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Senem Yazici Guvenc,Aleyna Cebi,Emine Can-Güven,Ahmet Demir,Farshid Ghanbari,Gamze Varank 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.9
The treatability of biodiesel wastewater by the electrochemical peroxidation process following acidificationpretreatment was investigated. Box-Behnken design, one of the experimental designs of response surface methodology,was applied to optimize the process parameters for chemical oxygen demand (COD), oil-grease, and volatile fatty acids(VFAs) removal from biodiesel wastewater. The process parameters, i.e., applied current, H2O2/COD ratio, and reactiontime, were optimized and the total cost of the process was determined. After the acidification process as a pretreatment,the COD, oil-grease, and VFAs removal efficiencies were 25.4%, 68.7%, and 50%, respectively. Optimum conditionsdetermined by the developed model for maximum oil-grease removal (98.2%) were applied: current 1.0 A, H2O2/CODratio 0.4, and reaction time 32.8 minutes. This devised Box-Behnken model predicted removal efficiencies of 45.5%,98.2%, and 49.5% for COD, oil-grease, and VFAs, respectively. The total cost of the process determined by the modeland obtained from the validation experiments was 2.03 €/m3 and 1.97 €/m3, respectively. The results of the study showedthat the applied process was efficient in pollutant removal from acidified biodiesel wastewater and the Box-Behnkendesign can be applied to explain the mechanism of the process and optimize the process parameters.
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Primary Immunodeficiencies in Children Initially Admitted with Gastrointestinal/Liver Manifestations
Murat Cakir,Nalan Yakici,Elif Sag,Gulay Kaya,Ayşenur Bahadir,Alper Han Cebi,Fazil Orhan 대한소아소화기영양학회 2023 Pediatric gastroenterology, hepatology & nutrition Vol.26 No.4
Purpose: The gastrointestinal system is the most commonly affected organ, followed by the lungs, in patients with primary immunodeficiency disease (PID). Hence, it is common for children with PIDs to present with gastrointestinal symptoms. We aimed to analyze the clinical and histopathological findings of patients who were initially admitted to pediatric gastroenterology/hepatology clinics and subsequently diagnosed with PIDs to identify the clinical clues for PIDs. Methods: The demographic, laboratory, and histopathological findings, treatment modality, and outcomes of patients initially admitted to the pediatric gastroenterology/hepatology unit and subsequently diagnosed with PIDs were recorded. Results: The study included 24 patients (58.3% male; median age [range]: 29 [0.5–204] months). Common clinical presentations included chronic diarrhea (n=8), colitis (n=6), acute hepatitis (n=4), and acute liver failure (n=2). The association of autoimmune diseases, development of malignant diseases, and severe progression of viral diseases was observed in 20.8%, 8.3%, and 16.6% of the patients, respectively. Antibody deficiency was predominantly diagnosed in 29.2% of patients, combined immunodeficiency in 20.8%, immune dysregulation in 12.5%, defects in intrinsic and innate immunity in 4.2%, autoinflammatory disorders in 8.3%, and congenital defects of phagocytes in 4.2%. Five patients remained unclassified (20.8%). Conclusion: Patients with PIDs may initially experience gastrointestinal or liver problems. It is recommended that the association of autoimmune or malignant diseases or severe progression of viral diseases provide pediatric gastroenterologists some suspicion of PIDs. After screening using basic laboratory tests, genetic analysis is mandatory for a definitive diagnosis.
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