The Relationship between Quiescent Infl ammatory Bowel Disease and Peripheral Polyneuropathy

( Zuleyha Akkan Cetinkaya ),( Yılmaz Cetinkaya ),( Mehmet Gencer ),( Mesut Sezikli ),( Hulya Tireli ),( Oya Ovunc Kurdas ),( Kayıhan Uluc ),( Onder Us ),( Tulin Tanrıdag ) 대한소화기기능성질환·운동학회 2011 Gut and Liver Vol.5 No.1

Background/Aims: Infl ammatory bowel disease is a chronic, recurrent disorder that involves multiple organ systems. Polyneuropathy is the most common neurological manifestation. The aim of the present study was to investigate the relationship between polyneuropathy and infl ammatory bowel disease. Methods: The study included 40 patients with infl ammatory bowel disease (20 with ulcerative colitis and 20 with Crohn`s disease) and 24 healthy controls. The patients had no clinical signs or symptoms of polyneuropathy. Nerve conduction studies were performed using an electroneuromyography apparatus. Results: Mean distal motor latencies, conduction velocities, and F wave minimum latencies of the right median nerve were signifi cantly abnormal in the patient group, compared to the healthy controls (p<0.05). Conclusions: Some electrophysiological alterations were observed in chronic infl ammatory bowel disease patients who showed no clinical signs. While investigating extra-intestinal manifestations in inflammatory bowel disease patients, nerve conduction studies must be performed to identify electrophysiological changes and subclinical peripheral polyneuropathy, which can subsequently develop. (Gut Liver 2011;5:57-60)

Risk Factors of Lymph Node Metastases with Endometrial Carcinoma

Cetinkaya, Kadir,Atalay, Funda,Bacinoglu, Ahmet Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Background: The purpose of this study was to investigate and evaluate risk factors for lymph node metastases (LNM) in cases of endometrial cancer (EC). Materials and Methods: A retrospective single institution analysis of patients surgically staged for EC at Ankara Oncology Education and Research Hospital from 1996 to 2010 was performed. Roles of prognostic factors, such as age, histological type, grade, depth of myometrial invasion, cervical involvement, peritoneal cytology, and tumor size, in the prediction of LNM were evaluated. Fisher's exact test and logistic regression analysis were used to assess the effects of various factors on LNM. Results: LNM was observed in 22 out of 247 patients (8.9%) and was significantly more common in the presence of tumors of higher grade, deep myometrial invasion (DMI), cervical involvement, size >2cm, and with positive peritoneal cytology. Logistic regression analysis revealed that DMI remained the only independent risk factor for LNM. NPV, PPV, sensitivity, and specificity for satisfying LNM risk were 98.0, 19.5, 86.3, and 65.3%, respectively for DMI. Conclusions: The incidence of LNM is influenced independently by DMI. If data support a conclusion of DMI, LND should be seriously considered.

CONVOLUTION PROPERTIES FOR ANALYTIC FUNCTIONS DEFINED BY q-DIFFERENCE OPERATOR

Cetinkaya, Asena,Sen, Arzu Yemisci,Polatoglu, Yasar The Honam Mathematical Society 2018 호남수학학술지 Vol.40 No.4

In this paper, we defined new subclasses of Spirallike and Robertson functions by using concept of q-derivative operator. We investigate convolution properties and coefficient estimates for both classes q-Spirallike and q-Robertson functions denoted by ${\mathcal{S}}^{\lambda}_q[A,\;B]$ and ${\mathcal{C}}^{\lambda}_q[A,\;B]$, respectively.

CONVOLUTION PROPERTIES FOR ANALYTIC FUNCTIONS DEFINED BY q-DIFFERENCE OPERATOR

Asena Cetinkaya,Arzu Yemis ci S en,Yasar Polatoglu 호남수학회 2018 호남수학학술지 Vol.40 No.4

In this paper, we de ned new subclasses of Spirallike and Robertson functions by using concept of q-derivative operator. We investigate convolution properties and coe cient estimates for both classes q-Spirallike and q-Robertson functions denoted by Sq [A;B] and Cq [A;B], respectively.

On spirallike functions related to bounded radius rotation

Asena Cetinkaya,Hakan Mete Tastan 호남수학회 2022 호남수학학술지 Vol.44 No.1

In the present paper, we prove the growth and distortion theorems for the spirallike functions class $\mathcal{S}_k(\lambda)$ related to boundary radius rotation, and by using the distortion result, we get an estimate for the Gaussian curvature of a minimal surface lifted by a harmonic function whose analytic part belongs to the class $\mathcal{S}_k(\lambda)$. Moreover, we determine and draw the minimal surface corresponding to the harmonic Koebe function.

Spirallike and Robertson Functions of Complex Order with Bounded Boundary Rotations

Ahuja, Om,Cetinkaya, Asena,Kahramaner, Yasemin Department of Mathematics 2019 Kyungpook mathematical journal Vol.59 No.2

Using the concept of bounded boundary rotation, we investigate various properties of two new generalized classes of spirallike and Robertson functions of complex order with bounded boundary rotations.

Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol

Balli, Umut,Cetinkaya, Burcu Ozkan,Keles, Gonca Cayir,Keles, Zeynep Pinar,Guler, Sevki,Sogut, Mehtap Unlu,Erisgin, Zuleyha Korean Academy of Periodontology 2016 Journal of Periodontal & Implant Science Vol.46 No.2

Purpose: The objective of this study was to investigate the effect of a dietary flavonoid, kaempferol, which has been shown to possess antiallergic, anti-inflammatory, anticarcinogenic, and antioxidant activities on the periodontium by histomorphometric analysis and on gingival tissue matrix metalloproteinase-1 (MMP-1), MMP-8, and tissue inhibitor of metalloproteinase-2 (TIMP-2) by biochemical analysis of rats after experimental periodontitis induction. Methods: Sixty Wistar rats were randomly divided into six groups of ten rats each, and silk ligatures were placed around the cervical area of the mandibular first molars for 15 days, except in the healthy control rats. In the experimental periodontitis groups, systemic kaempferol (10 mg/kg/2d) and saline were administered by oral gavage at two different periods (with and without the presence of dental biofilm) to all rats except for the ten non-medicated rats. Alveolar bone area, alveolar bone level, and attachment level were determined by histomorphometric analysis, and gingival tissue levels of MMP-1, MMP-8, and TIMP-2 were detected by biochemical analysis. Results: Significantly greater bone area and significantly less alveolar bone and attachment loss were observed in the kaempferol application groups compared to the control groups (P<0.05). In addition, gingival tissue MMP-1 and -8 levels were significantly lower in the kaempferol application groups compared to the control groups and the periodontitis group (P<0.001). There were no statistically significant differences in TIMP-2 levels between the kaempferol and saline application groups (P>0.05). Conclusions: Kaempferol application may be useful in decreasing alveolar bone resorption, attachment loss, and MMP-1 and -8 production in experimental periodontitis.

Healthy Life-Style Promoting Behaviour in Turkish Women Aged 18-64

Sonmezer, Hacer,Cetinkaya, Fevziye,Nacar, Melis Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Aim: In this study we aimed to investigate the healthy life-style behaviour of Turkish women and establish influencing features. Methods: This descriptive study performed by a questionnaire method was conducted in a primary health care centre, in an urban region in Kayseri, Turkey. Every midwife region belonging to the health care centre was accepted as a cluster, and a sample of 450 women between ages 18-64, was gathered from 9 midwife regions. The Health Promotion Life-style Profile (HPLP) was applied to evaluated the healthy lifestyle behaviour of 421 women that could be reached. T test, Tukey HSD with ANOVA, and chi square tests were used for analysis. Results: The mean total HPLP was $126.8{\pm}19.2$ (interpersonal support subscale, $74.3{\pm}14.1$; nutrition subscale, $73.6{\pm}12.6$; self-actualisation subscale, $70.6{\pm}11.9$; stress management subscale, $63.4{\pm}13.0$; health responsibility subscale, $61.2{\pm}13.2$; and exercise subscale, $47.1{\pm}15.0$). There was no statistically significant variation when evaluated for age, marital state, family type, economic status, and perception of self-health, smoking, and BMI. HPLP was high in people with an education of primary school and lower in university graduates, in people who lived mostly in the city centre and in individuals with chronic diseases. In conclusion, it was established that the health promoting behaviour in Turkish women is, in general, at a medium level, and women should be enlightened in order to develop and increase the habit of health preservation and promotion.

Is Target Oriented Surgery Sufficient with Borderline Ovarian Tumors? - Role of Accompanying Pathologies

Gungor, Tayfun,Cetinkaya, Nilufer,Yalcin, Hakan,Ozdal, Bulent,Ozgu, Emre,Baser, Eralp,Yilmaz, Nafiye,Caglar, Mete,Zergeroglu, Sema,Erkaya, Salim Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

Background: There are limited data in the literature related to concomitant genital or extra-genital organ pathologies in patients with borderline ovarian tumors (BOTs). The aim of this study was to evaluate our experience with 183 patients to draw attention to the accompanying organ pathologies with BOTs. Materials and Methods: One hundred eighty-three patients with BOTs, diagnosed and/or treated in our center between January of 2000 and March of 2013 were evaluated retrospectively. Data related to age, tumor histology, lesion side, disease stage, accompanying incidental ipsilateral and/or contralateral ovarian pathologies, treatment approaches, and follow-up periods were investigated. Incidental gynecologic and non-gynecologic concomitant organ pathologies were also recorded. Results: The mean age at diagnosis was 40.6 years (range: 17-78). Ninety-five patients (51%) were ${\leq}40$ years. A hundred and forty-seven patients (80%) were at stage IA of the disease. The most common type of BOT was serous in histology. Non-invasive tumor implants were diagnosed in 4% and uterine involvement was found 2% among patients who underwent hysterectomies. There were 12 patients with positive peritoneal washings. Only 17 and 84 patients respectively had concomitant ipsilateral and concomitant contralateral incidental ovarian pathologies. The most common type of uterine, appendicular and omental pathologies were chronic cervicitis, lymphoid hyperplasia and chronic inflammatory reaction. Conclusions: According to our findings most of accompanying pathologies for BOT are benign in nature. Nevertheless, there were additional malignant diseases necessitating further therapy. We emphasize the importance of the evaluation of all abdominal organs during surgery.

Hazardous Health Behaviour among Medical Students: a Study from Turkey

Nacar, Melis,Cetinkaya, Fevziye,Baykan, Zeynep,Yilmazel, Gulay,Elmali, Ferhan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

Background: Hazardous health behaviour in young people is an important factor that affects the individual risk for non-communicable diseases and other disorders later in life. This study aimed to determine the hazardous health behaviour of first and last class medical students of Erciyes University. Materials and Methods: This descriptive study was carried out with 240 medical students from the first and 130 students from the last (sixth) class. Data were obtained by questionnaire between March-April 2012. In total, 339 students were included with a response rate of 91.6%. Socio-demographic characteristics, school success, self-reported economic difficulties, health perceptions, hazardous health behaviour related to chronic disease, tobacco, alcohol, substance use, body weight, height, traffic, violence and nutrition were assessed in line with the literature. Results: Of the participants; 64.0% were from first and 36.0% were from the last class. Mean ages for the first and last classes were $19.4{\pm}1.5$ and $24.0{\pm}1.5years$, respectively. In the current study, males exhibited more hazardous behaviour than females. Sime 19.8% of the students in the study group used alcohol, 35.4% used a waterpipe, and 24.8% used tobacco at least once. These rates increased in both genders in the last class and the increase in males was significant. Some 3.8% of the students in the current study used pleasure-inducing illegal substances at least once. All the students participating in the current study were single, the number of males reported not using condoms (8.6%) was 4.56 times higher compared to females. Some 64.0% of the students did not perform physical activity lasting at least 30 minutes for five times a week, 13.0% did not sleep for mean 7-8 hours daily, males having a 2.9 times higher risk. More than 1/3 of the students did not consume cooked vegetable dishes and 1/4 did not consume fresh fruits and salads, the rates were higher among males. Conclusions: In the current study, hazardous health behaviour was prevalent among medical students, with higher risks among males and last class students. According to these results, medical curriculum may be focused on decreasing hazardous health behaviour. In addition, in order to prevent unhealthy behaviour, the number of youth-friendly health facilities should be increased.