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Yoo, Byoung-Sam,Yoo, Mi-Ae,Song, Young-Keun,Byun, Sang-Yo Korean Society for Biotechnology and Bioengineerin 2007 Biotechnology and Bioprocess Engineering Vol.12 No.6
The ability of heartwood extract of Morus bombycis in controlling the melanogenesis in B16 melanoma was investigated. An inhibitory effect was observed when the dose concentration was less than 10 mg/L. When the dose was 10 mg/L, the extracellular melanin accumulated was only 5% of the control. Proteome analysis with 2-D PAGE and MALDI-TOF showed that there were various proteins involved in inhibitory melanogenesis. It seems that down-regulation of TRP2, vacuolar proton-translocating ATPase 100 kDa subunit isoform a1-I and V-ATPase E2 subunit were involved in melanosome development and regulation that could reduce melanin synthesis.
EVALUATION OF FAST NEUTRON FLUENCE FOR KORI UNIT 3 PRESSURE VESSEL
Yoo, Choon-Sung,Kim, Byoung-Chul,Chang, Kee-Ok,Lee, Sam-Lai,Park, Jong-Ho Korean Nuclear Society 2006 Nuclear Engineering and Technology Vol.38 No.7
Three-dimensional neutron flux and fluence of Kori Unit 3 were evaluated using the synthesis technique described in Regulatory Guide 1.190 for all reactor geometry. For this purpose DORT neutron transport calculations from Cycle 1 to Cycle 15 were performed using BUGLE-96 cross-section library. The calculated flux and fluence were validated by comparing the calculated reaction rates to the measurement data from the dosimetry sensor set of the $5^{th}$ surveillance capsule withdrawn at the end of cycle 15 of Kori Unit 3. And then the best estimation of the neutron exposures for the reactor vessel beltline region was performed using the least square evaluation. These results can be used in the assessment of the state of embrittlement of Kori Unit 3 pressure vessel.