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2-bromopropane이 Sprague-Dawley 랫트의 blood-testis barrier에 미치는 영향
손화영,강부현,조성환,윤원기 충남대학교 수의과대학 동물의과학연구소 1997 動物醫科學硏究誌 Vol.5 No.-
This study was carried out to investigate the effect of 2-bromopropane, which recently caused occupational intoxication in Korea, on blood-testis barrier of Sprague-Dawley rats. 10 weeks old male Sprague-Dawley rats were treated with 3.5g/㎏ of 2-bromopropane for 3 consecutive days orally. 2-bromopropane treatment induced degeneration of spermatogonia but spermatocytes, spermatids, Sertoli cells and interstitial cells showed normal appearance. There was no effect observed on the Blood-testis barrier examination by hypertonic fluid or lanthanum was normal.