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      • KCI등재

        Taxonomic study of the subtribe Pemphredonina Dahlbom, 1835 (Hymenoptera: Crabronidae) with a new species and six new records from China

        Bashir Nawaz Haider,Yue Dan,Jiang Huifen,Ma Li,Li Qiang 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.4

        In this revision of the subtribe Pemphredonina (Crabronidae: Pemphredoninae: Pemphredonini) from China, we reported several species present in respected subtribe, out of which one species is new to science Passaloecus frontirugatus Bashir and Ma, sp. nov., and six species are recorded for the first time from China, including Polemistus palawanensis Tsuneki, Diodontus insidiosus Spooner, Diodontus handlirschi Kohl, Diodontus tiemudzhin Tsuneki, Diodontus spinicerus Kazenas, and Diodontus kuroo Tsuneki. A key to genera and the species of Diodontus and Passaloecus from China is also provided. Distributional records from China of each genus are also g

      • Isolation and Structure Elucidation, Molecular Docking Studies of Screlotiumol from Soil Borne Fungi Screlotium rolfsii and their Reversal of Multidrug Resistance in Mouse Lymphoma Cells

        Ahmad, Bashir,Rizwan, Muhammad,Rauf, Abdur,Raza, Muslim,Azam, Sadiq,Bashir, Shumaila,Molnar, Joseph,Csonka, Akos,Szabo, Diana Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4

        A new compound namely (13-(3,3-dihydroxypropyl)-1,6-dihydroxy-3,4-dihydro-1H-isochromen-8(5H)-one (1) was isolated from an ethyl acetate extract of the borne fungi Screlotium rolfsii. Its chemical structure was elucidated by spectroscopic analysis. Screlotiumol 1 were evaluated for their effects on the reversion of multidrug resistant (MDR) mediated by P-glycoprotein (P-gp) of the soil borne fungi. The multidrug resistant P-glycoprotein is a target for chemotherapeutic drugs in cancer cells. In the present study rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma which showed excellent MDR reversing effect in a dose dependent manner against mouse T-lymphoma cell line. Moreover, molecular docking studies of compound-1 also showed better results as compared with the standard. Therefore the preliminary results obtained from this study suggest that screlotiumol 1 could be used as a potential agent for the treatment of cancer.

      • Comparative Study of Carcinoembryonic Antigen Tumor Marker in Stomach and Colon Cancer Patients in Khyber Pakhtunkhwa

        Ahmad, Bashir,Gul, Bushra,Ali, Sajid,Bashir, Shumaila,Mahmood, Nourin,Ahmad, Jamshed,Nawaz, Seema Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

        Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis would be helpful to prevent/stop cancer from progressing to severe stage. In Khyber Pakhtunkhwa, Pakistan, most of the time, tumors are diagnosed with endoscopy and biopsy; therefore rare studies exist regarding the diagnosis of gastrointestinal (GIT) carcinomas based on tumor markers, especially CEA. Objectives: This study made a comparative analysis of CEA in admitted hospitalized stomach and colon cancer patients diagnosed as GIT with biopsy. Materials and Methods: In this study, a total of 66 cases were included. The level of CEA was determined in the blood of these patients using ELISA technique. Results: Out of 66 patients, the level of CEA was high in 59.1% of the total, 60.7% in colon cancer patients and 57.9 % in stomach cancer patients. Moreover, the incidence of colorectal and stomach cancer was greater in males as compared to females. Patients were more of the age group of 40-60 and the level of CEA was comparatively higher in patients (51.5%) with histology which was moderately differentiated, than patients with well differentiated and poorly differentiated tumor histology. Conclusions: CEA level was high in more than 50% of the total patients. Moreover, CEA exhibited higher sensitivity for colon than stomach cancer.

      • Level and Evaluation of Tumor Marker CA-125 in Ovarian Cancer Patients in Khyber Pakhtunkhwa, Pakistan

        Ahmad, Bashir,Nawaz, Seema,Ali, Sajid,Bashir, Shumaila,Mahmood, Nourin,Gul, Bushra Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis is necessary to prevent/stop cancer from progressing to a severe stage. In Khyber Paktunkhwa, Pakistan, many tumors are diagnosed with endoscopy and biopsy; rare studies exist regarding the diagnosis and evaluation of ovarian cancer, based on tumor markers like CA-125. Objectives: The objectives of this study were to investigate and evaluate levels of CA-125 in hospitalized ovarian cancer patients. Materials and Methods: In this study, a total of 63 admitted patients having ovarian cancer by biopsy were included. The level of CA-125 was determined in the blood of these patients using ELISA technique. Results: Out of 63 patients, the level of CA-125 was high in 52%. The affected individuals were more in the group of 40-60 and the level of CA-125 was comparatively higher in patients having moderately differentiated histology than those having well differentiated and poorly differentiated tumor histology. Moreover, the highest level of CA-125 was present among the patients having serous subtype of carcinoma and the common stage of carcinoma was stage II followed by stage III, I and IV. Conclusions: CA-125 level was high in more than 50% of the total patients. Moreover, CA-125 elevation was more common in serous subtype and stage II cancer patients.

      • KCI등재

        Dynamic Wetting in Microfluidic Droplet Formation

        Shazia Bashir,Xavier Casadevall i Solvas,Muhammad Bashir,Julia Margaret Rees,William Bauer Jay Zimmerman 한국바이오칩학회 2014 BioChip Journal Vol.8 No.2

        The extent to which the carrier fluid wets the walls of a microchannel is crucial in the droplet formation process for segmented flow microfluidic applications and can be influenced by the use of surfactants. Surfactants dynamically modify the microchannel surface leading to stabilization of the two phase interface, affecting the droplet formation process. An experimental study of the influence of hydrophobic surfactant (Span 80) during the formation of water-inoil droplets in a T-shaped microchannel geometry is presented and the wetting properties of the microchannel walls were characterized. The range of data to be analyzed on the microscale is estimated from the macroscopic interfacial tension and contact angle measurements. The critical micelle concentration (CMC) level at the microscale was estimated by observing the trend of droplet length variation with concentration of surfactant in a microchannel. Microchannels used in this work were fabricated using softlithography methods and bonded using a custom-made plasma bonding setup that does not require an ultra high vacuum chamber and hence saves the fabrication cost.

      • KCI등재

        A Study of the Thermal Properties of Nano-crystalline Binary Oxides Prepared by Co-precipitation Method

        Tahira Amer Bashir Ziya,Muhammad Naeem Ashiq,고재현,Farooq Bashir,Ghulam Shabbir 한국물리학회 2020 새물리 Vol.70 No.2

        The Thermal properties of nano-crystalline CeO2, FeO, MgO, Ho2O3, NiO and Y2O3, prepared by using the co-precipitation method, have been investigated using X-ray diffraction (XRD) at room temperature. The integrated intensity data obtained from the X-ray diffraction experiments was utilized to determine the temperature factor (B(T)), mean square amplitude of vibration (u2(T)), Debye temperature (D), melting point (Tm) and activation energy for vacancy formation (Ef ). The values of (B(T)) and (u2(T)) in the present case were found to be large while the values of D and Ef were found to be lower than the corresponding values reported for the binary oxides with large particle sizes. This suggests that a decrease in particle size from micro to nano-scale may induce weakening of the bonds. On a nano-scale as compared to ordinary size, the values of the melting points were found be higher for the heavier atomic oxides.

      • KCI등재

        Prediction of ultimate moment anchorage capacity of concrete filled steel box footing

        Muhammad Aun Bashir,Hitoshi Furuuchi,Tamon Ueda,M. Nauman Bashir 국제구조공학회 2013 Steel and Composite Structures, An International J Vol.15 No.6

        The objective of the study is to predict the moment anchorage capacity of the concrete filled steel box (CFSB) as footing by using the 3D finite element program CAMUI developed by authors' laboratory. The steel box is filled with concrete and concrete filled steel tube (CFT) column is inserted in the box. Numerical simulation of the experimental specimens was carried out after introducing the new constitutive model for post peak behavior of concrete in compression under confinement. The experimental program was conducted to verify the reliability of the simulation results by the FE program. The simulated peak loads agree reasonably with the experimental ones and was controlled by concrete crushing near the column. After confirming the reliability of the FEM simulation, effects of different parameters on the moment anchorage capacity of concrete filled steel box footing were clarified by conducting numerically parametric study.

      • Risk Factors of Prostate Cancer: a Case-control Study in Faisalabad, Pakistan

        Bashir, Muhammad Naeem,Ahmad, Muhammad Riaz,Malik, Akram Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

        Background: Prostate cancer is the third most commonly diagnosed cancer among males in Pakistan but very little is known about risk factors among the Pakistani population. Therefore a hospital-based, case-control study was carried out in Faisalabad to identify potential risk factors. Materials and Methods: This study was based on 140 prostate cancer cases and 280 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to assess the relationship between prostate cancer and different risk factors. Results: Family history of prostate cancer, age, smoking, obesity, consumption of red meat and frequent use of fat items significantly increased the prostate cancer risk (odds ratios and 95% confidence intervals of: 7.32; 1.79-29.8; 16.9, 5.60-50.8; 2.47, 1.17-5.18; 5.79, 2.66-12.6; 2.71, 1.07-6.91; and 3.39, 1.47-7.83, respectively. On the other hand, more consumption of fruit, fluid intake and better lifestyle (physical activity) significantly reduced the risk of developing prostate cancer with odd ratios and corresponding 95% confidence intervals of: 0.27, 0.11-0.61; 0.05, 0.02-0.12; and 0.28, 0.13-0.58. Conclusions: The results of the present study suggested that age, family history of prostate cancer, smoking, obesity, fluid intake, frequent use of fat items, consumption of fruits and better lifestyle might be associated with prostate cancer among Pakistani males.

      • KCI등재

        Dynamics of domestic violence in Kashmir: An interplay of multiple factors

        Bashir Aadil,Rafiq Misbah 한국사회복지학회 2023 Asian Social Work and Policy Review Vol.17 No.3

        Domestic violence is a widely prevalent phenomenon in the world. However, some of its features are culture‐specific. This study, therefore, attempts to study domestic violence in the context of Kashmir's culture. It draws on data collected through interviews with victims of domestic violence who were identified during a survey in Kashmir. The interview transcripts were analyzed and themes were drawn using the axial coding method (Corbin and Strauss). Classification of the themes into categories was based on similarities that they share and on the frequency with which they co‐occur. These categories gave a sense of dynamics of domestic violence operating in Kashmir. Data reveals that the causes of domestic violence in Kashmir operate at various levels, like individual, social, and cultural. Moreover, qualitative analysis of the interview transcripts visualize domestic violence in Kashmir as the interplay of the following categories, personal factors, communication factors, power factors, interpersonal factors , cultural factors, and situational factors. It is the geo‐political and social context of Kashmir that results in the unique dynamic of these causal factors which will help in designing and tailoring culture‐specific interventions to address the issue of domestic violence in Kashmir.

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