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Trong Luan NGUYEN,Minh Khang HUYNH,Nguyet Nuong HO,Tran Gia Bao LE,Nguyen Duy Hau DOAN 한국유통과학회 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.4
The UN’s 17 Sustainable Development Goals (2018) were created to address environmental pollution and climate change (SDGs). The goal of this study is to find out how well-informed Vietnamese students are about the SDGs. Knowledge, attitudes, and practice (KAP) questionnaires were used to survey 1,010 students across Vietnam’s universities, and the data was analyzed using SPSS software version 20. The findings suggest that both knowledge and attitude have a positive impact on the practice level. However, when comparing the correlation between the variables and the level of practice, advantage belongs to the relationship between the attitude and the level of practice (r = 0.982**, n = 1010, p = 0.00), the correlation between knowledge and practice level is weaker (r = 0.616**, n = 1010, p = 0.00). Statistical data also show that many Vietnamese students do not have access to information about the SDGs. The majority of the target population who have been contacted and have a basic understanding of the SDGs have done so through their academic degree. From there, it is clear that education is the most effective strategy for Vietnamese students to modify their environmental understanding and actions.
Predictive position and force control for shape memory alloy cylinders
Nguyen Trong Tai,Nguyen Bao Kha,안경관 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.8
In this paper, a linear lightweight electric cylinder constructed using shape memory alloy (SMA) is proposed. Spring SMA is used as the actuator to control the position and force of the cylinder rod. The model predictive control algorithm is investigated to compensate SMA hysteresis phenomenon and control the cylinder. In the predictive algorithm, the future output of the cylinder is computed based on the cylinder model, and the control signal is computed to minimize the error and power criterion. The cylinder model parameters are estimated by an online identification algorithm. Experimental results show that the SMA cylinder is able to precisely control position and force by using the predictive control strategy though the hysteresis effect existing in the actuator. The performance of the proposed controller is compared with that of a conventional PID controller.
Model Predictive Control for Shape Memory Alloy Cylinder
Nguyen Trong Tai,Nguyen Bao Kha,Kyoung Kwan Ahn 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
In this paper, a linear lightweight electric cylinder using SMA (Shape Memory Alloy) is proposed. The spring SMA is used as the actuator to control the position of the cylinder. The cylinder position is controlled by Model Predictive Control algorithm. In this controller, the cylinder model is estimated by online identification algorithm, so that SMA hysteresis effect will be compensated. Experimental results show that the position of the SMA cylinder is able to control precisely by using predictive control strategy though the hysteresis effect existing in this actuator. The performance of the proposed controller is also compared with the conventional PID controller and shown in this paper.??
Theanine attenuates memory impairments induced by <i>klotho</i> gene depletion in mice
Nguyen, Bao Trong,Sharma, Naveen,Shin, Eun-Joo,Jeong, Ji Hoon,Lee, Sung Hoon,Jang, Choon-Gon,Nah, Seung-Yeol,Nabeshima, Toshitaka,Yoneda, Yukio,Kim, Hyoung-Chun The Royal Society of Chemistry 2019 Food & Function Vol.10 No.1
<P>Theanine (γ-glutamylethylamide), an amino acid in tea, is a putative neuroprotective and antioxidant compound capable of improving lifespan and cognitive function. Because we previously reported cognitive dysfunction in <I>klotho</I> mutant mice <I>via</I> down-regulation of janus kinase 2 (JAK2) and signal transducer and activator of transcription3 (STAT3), M1 muscarinic cholinergic receptor (M1 mAChR), and ERK signaling, we, therefore, investigated whether self-administration of theanine affects memory dysfunction in response to <I>klotho</I> gene depletion in mice, and whether theanine modulates the JAK2/STAT3, M1 mAChR, and ERK signaling network. Theanine significantly attenuated memory impairments in <I>klotho</I> mutant mice. Moreover, theanine self-administration significantly attenuated inhibitions of JAK2/STAT3 phosphorylation, M1 mAChR expression, and ERK1/2 phosphorylation in the hippocampus of <I>klotho</I> mutant mice. Consistently, AG490, a JAK2/STAT3 inhibitor, dicyclomine, an M1 mAChR antagonist, or U0126, an ERK1/2 inhibitor, significantly counteracted theanine-induced attenuation of memory impairment induced by <I>klotho</I> gene depletion in mice. Our study suggests that theanine attenuates memory impairments in a genetic aging model <I>via</I> up-regulation of JAK2/STAT3, M1 mAChR, and ERK signaling.</P>
Trong Luan NGUYEN,Minh Khang HUYNH,Nguyet Nuong HO,Tran Gia Bao LE,Nguyen Duy Hau DOAN 한국유통과학회 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.1
Humans are facing many environmental challenges. Climate change, water pollution, global warming, and hazardous waste disposal are all issues that many countries throughout the world are dealing with. People’s psychology and consumer behavior are significantly affected by these challenges, particularly generation Z, which is immediately affected by environmental changes. Young people have a strong sense of curiosity and have access to readily updated knowledge. Today’s youth, in particular, live a civilized and responsible lifestyle. As a result, people recognize the significance of their own consumption behavior in affecting environmental change and are increasingly replacing them with green, ecologically friendly products as a fantastic method to mitigate their harmful consequences. In this research, there are four factors related to the young generation and environmental awareness that affect green consumption intention: perceived environmental responsibility, green knowledge, green attitude, and green product value. The goal of this study is to look into how detrimental environmental changes affect Generation Z’s green consumption habits. This study used primary data from over 1000 people in the age group, which was processed using the AMOS 20 software. All the characteristics described above had an impact on Generation Z’s green consumption intentions, according to the findings.
Methamphetamine-induced dopaminergic neurotoxicity as a model of Parkinson’s disease
Eun-Joo Shin,정지훈,Yeonggwang Hwang,Naveen Sharma,Duy-Khanh Dang,Bao-Trong Nguyen,나승열,Choon-Gon Jang,Guoying Bing,Toshitaka Nabeshima,Hyoung-Chun Kim 대한약학회 2021 Archives of Pharmacal Research Vol.44 No.7
Parkinson’s disease (PD) is a progressive neurodegenerativedisease with a high prevalence, approximately1 % in the elderly population. Numerous studies have demonstratedthat methamphetamine (MA) intoxication causedthe neurological defi cits and nigrostriatal damage seen inParkinsonian conditions, and subsequent rodent studies havefound that neurotoxic binge administration of MA reproducedPD-like features, in terms of its symptomatology andpathology. Several anti-Parkinsonian medications have beenshown to attenuate the motor impairments and dopaminergicdamage induced by MA. In addition, it has been recognized that mitochondrial dysfunction, oxidative stress, pro-apoptosis,proteasomal/autophagic impairment, and neuroinfl ammationplay important roles in inducing MA neurotoxicity. Importantly, MA neurotoxicity has been shown to share acommon mechanism of dopaminergic toxicity with that ofPD pathogenesis. This review describes the major fi ndingson the neuropathological features and underlying neurotoxicmechanisms induced by MA and compares them with Parkinsonianpathogenesis. Taken together, it is suggested thatneurotoxic binge-type administration of MA in rodents is avalid animal model for PD that may provide knowledge onthe neuropathogenesis of PD.
Mai, Huynh Nhu,Sharma, Naveen,Shin, Eun-Joo,Nguyen, Bao Trong,Nguyen, Phuong Tram,Jeong, Ji Hoon,Jang, Choon-Gon,Cho, Eun-Hee,Nah, Seung-Yeol,Kim, Nam Hun,Nabeshima, Toshitaka,Kim, Hyoung-Chun Elsevier 2018 Neurochemistry International Vol.116 No.-
<P><B>Abstract</B></P> <P>We demonstrated that activation of protein kinase Cδ (PKCδ) and inactivation of the glutathione peroxidase-1 (GPx-1)-dependent systems are critical for methamphetamine (MA)-induced recognition memory impairment. We also demonstrated that exposure to far-infrared rays (FIR) causes induction of the glutathione (GSH)-dependent system, including induction of the GPx-1 gene. Here, we investigated whether exposure to FIR rays affects MA-induced recognition memory impairment and whether it modulates PKC, cholinergic receptors, and the GSH-dependent system. Because the PKC activator bryostatin-1 mainly induces PKCα, PKCε, and PKCδ, we assessed expression of these proteins after MA treatment. MA treatment selectively increased PKCδ expression and its phosphorylation. Exposure to FIR rays significantly attenuated MA-induced increases in PKCδ phosphorylation. Importantly, bryostatin-1 potentiated MA-induced phosphorylation of PKCδ. MA treatment significantly decreased M1, M3, and M4 muscarinic acetylcholine receptors (mAChRs) and β2 nicotinic acetylcholine receptor expression. Of these, the decrease was most pronounced in M1 mAChR. Exposure to FIR significantly attenuated MA-induced decreases in the M1 mAChR and phospho-ERK<SUB>1/2</SUB>, while it facilitated Nrf2-dependent GSH induction. Dicyclomine, an M1 mAChR antagonist, and <SMALL>L</SMALL>-buthionine-(S, R)-sulfoximine (BSO), an inhibitor of GSH synthesis, counteracted against the protective potentials mediated by FIR. More importantly, the memory-enhancing potential of FIR rays was significantly counteracted by bryostatin-1, dicyclomine, and BSO. Our results suggest that exposure to FIR rays attenuates MA-induced impairment in recognition memory via up-regulation of M1 mAChR, Nrf2-dependent GSH induction, and ERK<SUB>1/2</SUB> phosphorylation by inhibiting PKCδ phosphorylation by bryostatin-1.</P> <P><B>Highlights</B></P> <P> <UL> <LI> FIR attenuated MA-induced memory dysfunction via inhibition of PKCδ phosphorylation. </LI> <LI> FIR potentiated MA-induced compensative induction in Nrf2 and GCLs levels. </LI> <LI> Inhibition of PKCδ phosphorylation activated M1 mAChR/Nrf-2/ERK<SUB>1/2</SUB> signaling. </LI> <LI> Protective activity of FIR was counteracted by PKC activation, dicyclomine, and BSO. </LI> </UL> </P>