Serological evidence of West Nile viral infection in archived swine serum samples from Peninsular Malaysia

Mohammed Nma Mohammed,Abd Rahaman Yasmin,Mohd Adzahan Noraniza,Siti Zubaidah Ramanoon,Siti Suri Arshad,Faruku Bande,Hussni O. Mohammed 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.3

West Nile virus (WNV), a neurotropic arbovirus, has been detected in mosquitos, birds, wildlife, horses, and humans in Malaysia, but limited information is available on WNV infection in Malaysian pigs. We tested 80 archived swine serum samples for the presence of WNV antibody and West Nile (WN) viral RNA using ID Screen West Nile Competition Multi-species enzyme-linked immunosorbent assay kits and WNV-specific primers in reverse transcription polymerase chain reaction assays, respectively. A WNV seroprevalence of 62.5% (50/80) at 95% confidence interval (51.6%–72.3%) was recorded, with a significantly higher seroprevalence among young pigs (weaner and grower) and pigs from south Malaysia. One sample was positive for Japanese encephalitis virus antibodies; WN viral RNA was not detected in any of the serum samples.

Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder

Ru-Band Lu,Yun-Hsuan Chang,Sheng-Yu Lee,Tzu-Yun Wang,Shu-Li Cheng,Po See Chen,Yen Kuang Yang,Jau-Shyong Hong,Shiou-Lan Chen 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.1

Objective: Valproic acid (VPA) is an anticonvulsant and commonly long term used as a mood stabilizer for patients with mood disorders. However its chronic effects on the hematological changes were noticed and need to be further evaluated. In this study, we evaluated, in Taiwanese Han Chinese patients with bipolar disorders (BD), the chronic effects of VPA or VPA plus dextromethorphan (DM) on the hematological molecules (white blood cell [WBCs], red blood cells [RBCs], hemoglobin, hematocrit, and platelets). Methods: In a 12-week, randomized, double-blind study, we randomly assigned BD patients to one of three groups: VPA plus either placebo (VPA+P, n = 57) or DM (30 mg/day, VPA+DM30, n = 56) or 60 mg/day (VPA+DM60, n = 53). The Young Mania Rating Scale and Hamilton Depression Rating Scale were used to evaluate symptom severity, and the hematological molecules were checked. Results: Paired t test showed that the WBC, neutrophils, platelets and RBCs were significantly lowered after 12 weeks of VPA+P or VPA+DM30 treatment. VPA+DM60 represented the protective effects in the WBCs, neutrophils, and RBCs but not in the platelets. We further calculated the changes of each hematological molecules after 12 weeks treatment. We found that combination use of DM60 significantly improved the decline in neutrophils induced by the long-term VPA treatment. Conclusion: Hematological molecule levels were lower after long-term treatment with VPA. VPA+DM60, which yielded the protective effect in hematological change, especially in the neutrophil counts. Thus, DM might be adjunct therapy for maintaining hematological molecules in VPA treatment.

LOW-POWER ANALOG FRONT ENDS FOR RF RECEIVERS

Song,Band Sup,Wilson,Dale G. 대한전자공학회 1995 ICVC : International Conference on VLSI and CAD Vol.4 No.1

Future digital wireless receivers will be built with quadrature RF front ends and baseband DSPs. Although the quadrature demodulation greatly simplifies the interface between the RF stage and the baseband DSP by eliminating the selective IF filters, it requires accurate quadrature carriers and path gain matching unless implemented digitally. This paper addresses design issues of analog front ends for digital wireless applications and discusses design tradeoffs for low power integration in CMOS.

액취증의 수술치료에 대한 임상 고찰

고양실,윤영복,방유현,박종섭 大韓成形外科學會 1984 Archives of Plastic Surgery Vol.11 No.2

Osmidrosis is caused by excessive axillary apocrine serection with foul odor. It causes ruined clothing and extreme social embarassement. Many sorts of surgical technique did not give satisfactory results in reduction of axillary secretion or scar or limitation of motion of the shoulder and /or disruption of the wounds. To prevent unsatisfactory results. we use the 'flap to graft conversion' technique, using two incisions over the axillary folds and we got satisfactory results. We reviewed 27 patients who where treated with this technique postoperatively. 1. We controlled bleedings completely and did not use the drains. 2. To ever the incisional edges, the mattress suture was preferable to the simple suture, which probably reduce formation of the epithelial cyst. 3. Light dressing was replaceble with moderate abduction of the arms than bulky bolus dressing. 4. With satisfactorial reduction of the axillary foul odor, there were linear scars without contracture or hypertrophy.

SH-SY5Y Human Neuroblastoma Cell에서 에스트로겐의 신경세포 보호효과에 대한 기전

염지현,김희,홍현석,방오영,허균,묵인희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.1

Apoptosis is one major mechanism underlying neuronal cell death in degenerative diseases in the central nervous system. Previous studies have shown that estrogen has neuroprotective effects in several neuronal cell death model systems. In the present study, we established a staurosporine-induced apoptotic neuronal cell death system with human SH-SY5Y cell line. 17b-estradiol(E2) blocked staurosporine-induced apoptosis of SH-SY5Y cells as revealed by MTT as well as LDH assay. The cells showed typical DNA fragmentation at 4 h and 8 h following staurosporine treatment, which was attenuated by E2 pretreatment. Staurosporine-induced chromatin condensation was also reduced by E2 treatment. Because apoptotic stimuli are known to induce caspase-3 activation and PARP cleavage, we examined whether E2 blocks these processes. E2 markedly attenuated staurosporine-induced casapase-3 activation and PARP cleavage. This study shows that E2 blocks staurosporine-induced apoptosis in SH-SY5Y human neuroblastoma cells, suggesting that E2 is a neuroprotective agent that may be used for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Strategies for SMEs based on a PEST-SWOT-AHP Analysis in Response to the lntroduction of the product Liability Law

( Jun Hyeok Seo ),( Bok Soo Ko ),( Band Sung Mingbae ) 한국품질경영학회 2014 한국품질경영학회 학술대회 Vol.2014 No.2

To formulate strategies for small and medium-sized manufacturing enterprises (SMEs) in response to the enforcement of the product liability (PL) law, factors that influence the enforcement of the PL law were identified through a political, economic, social, and technological (PEST) analysis. Furthermore, the relative importance was proposed for each area through a strengths, weaknesses, opportunities, and threats analytic hierarchy process (SWOT-AHP) analysis of the identified factors. In order to identify the relative importance of each area, a pairwise analysis was conducted through a questionnaire survey targeting experts in businesses related to PL. The results suggest the greater importance of opportunities and strengths than threats and weaknesses, indicating that the enforcement of the PL law would provide SMEs more opportunities than burdens. Through these results the S/O, S/T, W/O, W/T strategies for SMEs, which can be preferentially implemented, were proposed.

이동 컴퓨팅 환경에서 이동 노드를 위한 효율적인 검사점 기록 및 메시지 로깅 프로토콜의 설계

안진호(Jin-Ho Ahn),방승준(Seung-Jun Band),안용선(Yong-Sun Ahn),김지은(Ji-Eun Kim) 한국정보기술학회 2009 한국정보기술학회논문지 Vol.7 No.4

In this paper, we propose a sender-based message logging protocol with checkpointing to efficiently consider constraints of mobile nodes. This protocol requires low overhead for maintaining checkpoints and message log information despite movements of nodes and allows recovery procedures of failed processes on other nodes to be performed even in case of their disconnection. In particular, in the proposed protocol, two-phase garbage collection algorithm is designed to have each process' volatile storage for saving message log full as late as possible and incur low failure-free overhead while ensuring the entire system consistency in case of future failures. Simulation results show that this two-phase garbage collection algorithm significantly reduces the number of forced checkpoints and checkpointing control messages compared with the existing one.

대상 포진 환자의 포진후 신경통 방지에 관한 교감신경 차단술의 효과

고우석,박상만,김방순,신동엽 ( Woo Seok Koh,Sang Man Park,Band Soon Kim,Dong Yeop Shin ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.4

Background: Many investigators have advocated neural and especially regional sympathetic blockade for acute herpe. zoster pain. Some believe that nerve blocks not. only relieve acute pain but also, if given early in the course of clinical disease, prevent progression to postherpetic neuralgia. Objective : The purpose of this study was to evaluate the preventive effect of sympathetic blockade on herpes zoster Methods : Fifteen patients with herpes zoster were treated with sympathetic blocks according to the severity of pain. Results : The total score of pain degree decreased from 3.4 to 1.1 with sympathetic blocks in 15 patients in 2 months. Sympathetic blocks prevented or relieved postherpetic neuralgia in more than 90% of patients treated within 2 weeks of the onset of the acute phase of the disease and in more than 85% of patients over 60. Conclusion . Sympathetic blocks are effective in preventing postherpetic neuralgia if applied soon after the onset of the acute phase of herpes zoster. (Kor J Dermatol 1997;35(4): 620-626)

Evaluating drought effect on MODIS Gross Primary Production (GPP) with an eco-hydrological model in the mountainous forest, East Asia

HWANG, TAEHEE,KANG, SINKYU,KIM, JOON,KIM, YOUNGIL,LEE, DOWON,BAND, LAWRENCE Blackwell Publishing Ltd 2008 Global change biology Vol.14 No.5

<P>Abstract</P><P>Surface soil moisture dynamics is a key link between climate fluctuation and vegetation dynamics in space and time. In East Asia, precipitation is concentrated in the short monsoon season, which reduces plants water availability in the dry season. Furthermore, most forests are located in mountainous areas because of high demand for agricultural land, which results in increased lateral water flux and uneven distribution of plant available water. These climatic and topographic features of the forests make them more vulnerable to drought conditions. In this study, the eco-hydrological model (Regional Hydro-Ecological Simulation System) is validated with various water and carbon flux measurements in a small catchment in Korea. The model is then extended to the regional scale with fine-resolution remote sensing data to evaluate the Moderate Resolution Imaging Radiometer (MODIS) leaf area index and gross primary productivity (GPP) products. Long-term model runs simulated severe drought effect in 2001 well, which is clearly shown in the ring increment data. However, MODIS GPP does not capture this drought effect in 2001, which might be from a simplified treatment of water stress in the MODIS GPP algorithm. This study shows that the MODIS GPP products can potentially overestimate carbon uptake specifically during drought conditions driven by soil water stress.</P>

Generalized Anxiety Disorder, Comorbid Major Depression and Heart Rate Variability: A Case-Control Study in Taiwan

Hsin-An Chang,Chuan-Chia Chang,Nian-Sheng Tzeng,Terry B. J. Kuo,Ru-Band Lu,San-Yuan Huang 대한신경정신의학회 2013 PSYCHIATRY INVESTIGATION Vol.10 No.4

Objective Decreased heart rate variability (HRV) has been reported in generalized anxiety disorder (GAD), but the results are mixed. Little is known about the impact of comorbid major depression (MD) on HRV in GAD patients. Both issues necessitate further investigation. Methods Twenty unmedicated, physically healthy GAD patients, 20 GAD patients with a secondary diagnosis of MD, 40 MD patients and 60 matched controls were recruited. We used the Hamilton Anxiety Rating Scale and the Hamilton Depression Rating Scale to assess anxiety and depression severity, respectively. Cardiac autonomic function was evaluated by measuring HRV parameters. Frequency-domain indices of HRV were obtained. Results Three patient groups had more anxiety and depression symptoms than control subjects, but heart rates (HRs) were significantly elevated only in GAD patients with comorbid depression. Relative to controls, GAD patients had reduced HRV while GAD patients with comorbid depression displayed the greatest reductions in HRV among three patients groups. Correlation analyses revealed anxiety/depression severity significantly associated with HRs, variance, LF-HRV and HF-HRV. However, separately analyzing among individual groups and adjusting for HRV-associated covariables rendered the correlations non-significant. Conclusion Our results suggest that reduction in HRV is a psychophysiological marker of GAD and individuals with comorbid GAD and MD may be distinguished based on psychophysiological correlates (for example, HF-HRV) from non-comorbid GAD patients. Taken into account that comorbid depression may confer increased risks for cardiovascular events in GAD patients, this subgroup of GAD patients may benefit better from cardiovascular risk reduction strategies.