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        • Ghrelin is Present in Teeth

          Aydin,,Suleyman,Ozercan,,I,brahim,Hanefi,Geckil,,Hikmet,Dagli,,Ferda,Aydin,,Suna,Kumru,,Sinem,Kilic,,Nermin,Sahin,,I,brahim,Ozercan,,Mehmet,Resat Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.3

          Ghrelin belongs to the family of a gut-brain hormone that promotes food intake and controls energy balance. Recently, it has also been shown to regulate bone formation directly. Dental tissue shares several functional, developmental and anatomical similarities with bone, and in the present study we have investigated the presence of ghrelin in 44 human teeth using immunocytochemistry and radioimmunoassay. Both methods showed that the hormone is present in canines and molars, mainly in the odontoblasts but also in the pulp. Ghrelin could potentially play interesting physiological roles in teeth.

        • Determination of antibiotics by SPE-LC-MS/MS in wastewater and risk assessment

          Aydin,,Senar,Aydin,,Mehmet,E.,Ulvi,,Arzu,Kilic,,Havva Techno-Press 2018 Advances in environmental research Vol.7 No.3

          In this study, conditions of solid phase extraction (SPE) for determination of some antibiotics such as trimethoprim, oxytetracycline, erythromycin, clarithromycin, azythromycin, doxycycline, sulfamethazine, ciprofloxacin, chlortetracycline, sulfamethoxazole in wastewaters were optimized. After the optimum volume and pH of the sample were determined, the effect of the concentration of the compounds and matrix were investigated. The highest recovery rates for antibiotic compounds were determined between 82% and 105% in 200 mL sample volume and pH 2.5. Then, antibiotic compounds were investigated in influent and effluent samples taken from Konya Urban Wastewater Treatment Plant. The concentration of the antibiotics was detected range of 0.11-101 ng/L in influent waters and <dl-288 ng/L in effluent samples in wastewater treatment plant. Hazard quotients (HQs) of antibiotic compounds determined in WWTP effluents to evaluate the risk towards different aquatic organisms (algae, Daphnia magna and fish) were determined. Azythromycin for fish and erythromycin, sulfamethoxazole, ciprofloxacin, clarithromycin for algae posed a moderate risk while azythromycin, ciprofloxacin, clarithromycin, oxytetracycline posed a high risk for algae in the receiving environment.

        • KCI등재후보SCOPUS

          ON SOME PROPERTIES OF THE SPACES

          Aydin,Gürkanli 장전수학회 2009 Proceedings of the Jangjeon mathematical society Vol.12 No.2

          For 1 ≤ p < ∞, Ap (Rn) denotes the space of all complex-valued functions in L¹ (Rn) whose Fourier transforms [수식] belong to Lp(Rn). A number of authors such as Larsen, Liu and Wang [12], Martin and Yap [14], Lai [11] worked on this space. Some generalizations to the weighted case was given by Gurkanli [7], Feichtinger and Gurkanli [4], Fischer, Gurkanli and Liu [5]. In the present paper we give another generalization of Ap (Rn) to the generalized Lebesgue space Lp(x)(Rn): We de…ne A[수식](x) (Rn) to be the space of all complex-valued functions in L[수식] (Rn) whose Fourier transforms [수식] belong to the generalized Lebesgue space Lp(x)(Rn). We endow it with a sum norm and show that A[수식](x) (Rn) is an Sw(Rn) space [2]. Further we discuss the multipliers of A[수식](x) (Rn).

        • Poster Session:PS 0503 ; Nephrology : Reasons of Emergency Department Admission of ESRD Patients : A Retrospective Analysis

          ( Attila Aydin ), ( Cemile Aydin ), ( Selma Karaahmetogluozkan ), ( Zeynep Guven ), ( Rukiye Kara ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

          Background: End stage renal failure is an increasing clinical problem. That is why we should prevent it and capture patients in earlier stages in order to stop their progression. We should determine the causes of hospitalization and acute complications. Methods: The patients who were hospitalized for End Stage Renal Disease (ESRD) between March 2009-2011 patients were studied. We studied the causes of hospitalization in concern with established parameters. The datas were analyzed in SPSS program. Results: The total number of patients were 98 including 50 men and 48 women. The ages of patients were between 27-93. Chronic Kidney Disease (CKD) duration was 2-240 months, the dialysis duration was 0.5-240 months. The most common cause of emergency department admission was infection 39 (%39.8). The Patients admitted with an infection were taken dialysis treatment longer than other patients (p=0.034) and they had a higher initial hemoglobin level (p=0.002) and were hospitalized longer than the other patients (p=0.047). The most common type of infection was pneumonia (%43.6). The most common cause of mortality was sepsis with %40 and pneumonia with %20. There was no statistically difference in terms of albumin level between patients with infection and the others. Although in the exitus group albumin was statically lower than the survivors (p<0.05). Conclusions: The most common cause of ESRD was infection. The most common cause of mortality was also infection; sepsis and pneumonia. We determined that a low albumin level was a bad prognostic factor.

        • KCI등재SCOPUS

          UWB Rectangular Microstrip Patch Antenna Design in Matching Liquid and Evaluating the Classification Accuracy in Data Mining Using Random Forest Algorithm for Breast Cancer Detection with Microwave

          Emine,Avşar,Aydin,Emine,Avşar,Aydin 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.5

          The most common type of cancer for a female is breast cancer in the world. Regular checks and effective-timely treatment are noteworthy parameters for patients' survival struggle . Against existing imaging methods, microwave imaging method has been considered more powerful and effective method by many researchers. In this paper, comprehensive design equations and parameters of rectangular microstrip patch antenna (RMPA) are given for microwave breast cancer detection. The layered breast model with a spherical tumor that was placed into the fibro-glandular layer was created by using CST Microwave Studio Software, and it was embedded in canola oil to decrease the distorted signals between the transmitting and receiving antennas. The RMPA has a wideband performance from 3 to 18 GHz. The simulation results show that differences in the electric field and reflection coefficients might more efficiently give a possibility to assign the tumor in the breast model. In addition, in this study, the data obtained from these experiments are classified by using the random forest algorithm from the data mining methods. According to the classification result, the random forest algorithm can diagnose breast cancer by classifying the tumor as 94% accuracy.

        • KCI등재SCOPUS

          Antihypertensive Role of Glossopharyngeal Nerve Stimulation by Nifedipine Using as Calcium Channel Blocking Agent in Hypertension: An Experimental Study

          Mehmet,Dumlu,Aydin,Ednan,Bayram,Zekai,Halici,Nazan,Aydin,Canan,Atalay,Hlzlr,Ulvi,Dilcan,Kotan,Cemal,Gundogdu 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.11

          Nifedipine is a therapeutic drug in acute attacks of hypertension because of its rapid absorption from oral mucosa. Taste receptors are innervated by glossopharyngeal nerves (GPN) as well as by facial and vagal nerves. Sensory neurons of the GPNs are localised in the petrous ganglion (PG). Transection of the taste sensitive GPN fibres causes taste bud and PG degeneration and spontaneous hypertension. In this study, the role of chemical stimulation of the taste buds of the GPN by nifedipine and its role in treatment of hypertension were investigated in rabbits. Nifedipine was dropped sublingually (20 mg) for 4 days in the study group, followed by measuring blood pressures again. Then, the lingual branches of GPNs were cut. One month later, blood pressures were measured for 4 days. All animals were sacrificed humanely at the end of the experiment, and normal and degenerated neuron densities in the petrosal ganglions were enumerated stereologically. The antihypertensive effect of nifedipine decreased after GPNs denervation, in accordance with the increase of degenerated neurons in the PG. The chemical stimulation of taste buds of the GPNs by nifedipine may be an important effect of nifedipine application in addition to its calcium channel blocking effect. The rapid decrease in blood pressure following sublingual use of nifedipine may also result from the direct stimulation of taste buds innervated by the GPNs. Nifedipine is a therapeutic drug in acute attacks of hypertension because of its rapid absorption from oral mucosa. Taste receptors are innervated by glossopharyngeal nerves (GPN) as well as by facial and vagal nerves. Sensory neurons of the GPNs are localised in the petrous ganglion (PG). Transection of the taste sensitive GPN fibres causes taste bud and PG degeneration and spontaneous hypertension. In this study, the role of chemical stimulation of the taste buds of the GPN by nifedipine and its role in treatment of hypertension were investigated in rabbits. Nifedipine was dropped sublingually (20 mg) for 4 days in the study group, followed by measuring blood pressures again. Then, the lingual branches of GPNs were cut. One month later, blood pressures were measured for 4 days. All animals were sacrificed humanely at the end of the experiment, and normal and degenerated neuron densities in the petrosal ganglions were enumerated stereologically. The antihypertensive effect of nifedipine decreased after GPNs denervation, in accordance with the increase of degenerated neurons in the PG. The chemical stimulation of taste buds of the GPNs by nifedipine may be an important effect of nifedipine application in addition to its calcium channel blocking effect. The rapid decrease in blood pressure following sublingual use of nifedipine may also result from the direct stimulation of taste buds innervated by the GPNs.

        • KCI등재

          Simulation of Soil Hydrological Components in Chuncheon over 30 years Using E-DiGOR Model

          Aydin,,Mehmet,Jung,,Yeong-Sang,Yang,,Jae-E.,Lee,,Hyun-Il,Kim,,Kyung-Dae Korean Society of Soil Science and Fertilizer 2012 한국토양비료학회지 Vol.45 No.4

          The hydrological components of a sandy loam soil of nearly level in Chuncheon over 30 years were computed using the E-DiGOR model. Daily simulations were carried out for each year during the period of 1980 to 2009 using standard climate data. Reference evapotranspiration and potential soil evaporation based on Penman-Montheith model were higher during May to August because of the higher atmospheric evaporative demand. Actual soil evaporation was mainly found to be a function of the amount and timing of rainfall, and presumably soil wetness in addition to atmospheric demand. Drainage was affected by rainfall and increased with a higher amount of precipitation and soil water content. Excess drainage occurred throughout rainy months (from July to September), with a peak in July. Therefore, leaching may be a serious problem in the soils all through these months. The 30-year average annual reference evapotranspiration and potential soil evaporation were 951.5 mm and 714.2 mm, respectively. The actual evaporation from bare soil varied between 396.9-528.4 mm and showed comparatively lesser inter-annual variations than drainage. Annual drainage rates below 120 cm soil depth ranged from 477.8 to 1565.9 mm. The long-term mean annual drainage-loss was approximately two times higher than actual soil evaporation.

        • KCI등재SCIESCOPUS

          Numerical determination of crack width for reinforced concrete deep beams

          Aydin,Demir,Naci,Caglar 사단법인 한국계산역학회 2020 Computers and Concrete, An International Journal Vol.25 No.3

          In the study, a new, simple and alternative formula is proposed to calculate numerically crack widths of concrete on a finite element (FE) model. By considering more general tension softening behavior of concrete, the proposed expression is derived irrespective of any tension softening model given in the literature or design codes. The test results of six reinforced concrete (RC) deep beams having different geometrical and material properties selected from a recent existing experimental study of the authors are used to verify the accuracy and reliability of the proposed formula and the created numerical FE models of the specimens. Moreover, the crack width results obtained from the FE models are compared with the test results to see the performance of the proposed formula. The results of the study demonstrate that the proposed formula gives very accurate results in a comparison with the test results. The ratios of errors on the results stay commonly at an acceptable level as well. Consequently, the proposed formula is quite simple, unique, and robust to determine crack widths of RC deep beams on an FE model.

        • KCI등재

          SOME RESULTS ON GENERALIZED LIE IDEALS WITH DERIVATION

          Aydin,,Neset,Kaya,,Kazim,Golbasi,,Oznur The Youngnam Mathematical Society Korea 2001 East Asian mathematical journal Vol.17 No.2

          Let R be a prime ring with characteristic not two. U a (${\sigma},{\tau}$)-left Lie ideal of R and d : R$\rightarrow$R a non-zero derivation. The purpose of this paper is to invesitigate identities satisfied on prime rings. We prove the following results: (1) [d(R),a]=0$\Leftrightarrow$d([R,a])=0. (2) if $(R,a)_{{\sigma},{\tau}}$=0 then $a{\in}Z$. (3) if $(R,a)_{{\sigma},{\tau}}{\subset}C_{{\sigma},{\tau}}$ then $a{\in}Z$. (4) if $(U,a){\subset}Z$ then $a^2{\in}Z\;or\;{\sigma}(u)+{\tau}(u){\in}Z$, for all $u{\in}U$. (5) if $(U,R)_{{\sigma},{\tau}}{\subset}C_{{\sigma},{\tau}}$ then $U{\subset}Z$.

        • KCI등재SCOPUS

          CONSTANT CURVATURE FACTORABLE SURFACES IN 3-DIMENSIONAL ISOTROPIC SPACE

          Aydin,,Muhittin,Evren Korean Mathematical Society 2018 대한수학회지 Vol.55 No.1

          In the present paper, we study and classify factorable surfaces in a 3-dimensional isotropic space with constant isotropic Gaussian (K) and mean curvature (H). We provide a non-existence result relating to such surfaces satisfying ${\frac{H}{K}}=const$. Several examples are also illustrated.

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