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        Preoperative Embolization of Cerebral Arteriovenous Malformations with Silk Suture and Particles: Technical Considerations and Outcomes

        Jordan R. Conger,Avery J. Evans,Dale Ding,Daniel M. Raper,Robert M. Starke,Christopher R. Durst,Kenneth C. Liu,Mary E. Jensen 대한뇌혈관외과학회 2016 Journal of Cerebrovascular and Endovascular Neuros Vol.18 No.2

        Objective:Embolization of cerebral arteriovenous malformations (AVMs) is commonly performed prior to surgical resection in order to reduce intraoperative bleeding and improve the safety of resection. Although most modern embolization procedures utilize permanent embolic agents, silk suture and polyvinyl alcohol (PVA) particles may offer unique advantages for preoperative devascularization. The aims of this retrospective cohort study are to describe the technical considerations and determine the outcomes for preoperative silk suture and PVA particle embolization (SPE) of AVMs. Materials and Methods:We performed a retrospective review of our AVM embolization database. AVM patients who underwent preoperative SPE and subsequent surgical resection were included for analysis. Baseline patient demographics, AVM characteristics, embolization and operative records, and post-treatment outcomes were reviewed. Results:A total of 11 patients who underwent 12 preoperative SPE procedures were included for analysis. Five AVMs were ruptured (45%), and the median nidus volume was 3.0 cm3 (range: 1.3-42.9 cm3). The Spetzler-Martin grade was I-II in seven patients (64%) and III-IV in four patients (36%). The degree of nidal obliteration was less than 25% in two procedures (17%), 25-50% in one procedure (8%), 50-75% in eight procedures (67%), and greater than 75% in one procedure (8%). The rates of post-embolization AVM hemorrhage and mortality were 8% and 0%, respectively. The postoperative angiographic obliteration rate was 100%, and the modified Rankin Scale score improved or stable in 91% of patients (median follow-up duration 2 months). Conclusion:Preoperative AVM SPE affords a reasonable risk to benefit profile for appropriately selected patients.

      • KCI등재후보

        Balloon Anchor Technique for Pipeline Embolization Device Deployment Across the Neck of a Giant Intracranial Aneurysm

        Dale Ding,Robert M. Starke,Avery J. Evans,Mary E. Jensen,Kenneth C. Liu 대한뇌혈관외과학회 2014 Journal of Cerebrovascular and Endovascular Neuros Vol.16 No.2

        Treatment of giant intracranial aneurysms, via either surgical or endovascularapproaches, is associated with a high level of technical difficulty aswell as a high rate of treatment-related morbidity and mortality. Flow-divertingstents, such as the Pipeline embolization device (PED), have drasticallyaltered the therapeutic strategies for the treatment of giant aneurysms. Gaining endovascular access using a microcatheter to the portion of theparent artery distal to the aneurysm neck is requisite for safe and effectivestent deployment. Giant aneurysms are often associated with vasculartortuosity, which necessitates significant catheter support systems to enablemaneuvering of PEDs across the aneurysm neck. This is also requiredin order to reduce the probability of stent herniation within giantaneurysms. We report on a case of a giant supraclinoid internal carotidartery (ICA) aneurysm which was treated successfully with a PED utilizinga balloon anchor technique to facilitate direct microcatheter access acrossthe aneurysm neck.

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